ChromosOmics - Database


Icon by Leon Liehr              



                                                     >3950 breakpoints from ~1900 cases included                                                  
  COUNTER

How to cite this database:
-
Liehr T. 2024. Constitutional chromosomal breakpoints.
https://cs-tl.de/DB/CA/BPs/0-Start.html [accessed on ...]



Visitors

in 2023: 330
in 2022: ~300
in 2021: 367

last update: 10. Jan. 2024

[VG-Wort ()]

Created by Dr. Thomas Liehr (PhD)
professional affiliation: Institute of Human Genetics, 07740 Jena, Germany;
e-mail: Thomas.Liehr@med.uni-jena.de or: LiehrT@web.de


            

AIM OF THIS PAGE Number of characterized breakpoints (bps) by chromosome How to use this page
  BREAKPOINTS BY CHROMOSOME
chr. 1
p3
p2
p1
q1
q2
q3
q4

 recurrent
chr. 2
p2
p1
q1
q2
q3



 recurrent  		 chr. 3
p2
p1
q1
q2




 recurrent  		chr. 4
p1
q1
q2
q3




recurrent
chr. 5
p1
q1
q2
q3




recurrent  		chr. 6
p2
p1
q1
q2




recurrent  		chr. 7
p2
p1
q1
q2
q3



 recurrent  		chr. 8
p2
p1
q1
q2




recurrent
chr. 9
p2
p1
q1
q2
q3

recurrent 		chr. 10
p1
q1
q2
recurrent 		chr. 11
p1
q1
q2
recurrent 		chr. 12
p1
q1
q2



 recurrent 		chr. 13
p1
q1
q2
q3
recurrent 		chr. 14
p1
q1
q2
q3
recurrent 		chr. 15
p1
q1
q2
recurrent 		chr. 16
p1
q1
q2
recurrent
chr. 17
p1
q1
q2
recurrent 		chr. 18
p1
q1
q2
recurrent		 chr. 19
p13
p12~q12
q13


recurrent		 chr. 20
p1
q1
recurrent 		chr. 21
p1
q1
q2


recurrent 		chr. 22
p1
q1
recurrent 		X-chr.
p2
p1
q1
q2

recurrent 		Y-chr.
p1
q1
recurrent
DISCLAIMER
link helpful for diagnostics

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References
Aim of this page

1. collect all cases of constitutional breakpoints in infertile and mentally retarded from Jena lab since 1998.
2. find out about repeatedly showing up breakpoints and iknclude in a seperate webpage.
3. provide data to find clusters of breakpoints in the human genome.

For inversions see also Human Polymorphic Inversion DataBase
How to use this page?

This page is organized like the 'sister-page' on small supernumerary marker chromosomes (sSMC)
- the structure is explained here.

 Also take care that the nomenclature here may not always be done exactly acc. to ISCN !!
Genomic size of human chromosomes (GRCh37/hg19)

chromosome size in Mb
1 249,250621
2 243,199373
3 198,02243
4 191,154276
5 180,91526
6 171,115067
7 159,138663
8 146,364022
9 141,213431
10 135,534747
11 135,006516
12 133,851895
13 115,169878
14 107,34954
15 102,531392
16 90,354753
17 81,195210
18 78,077248
19 59,128983
20 63,02552
21 48,129895
22 51,304566
X 155,27056
Y 59,373566
overall 3095,67741
    
Number of breakpoints per chromosomes included in this page 

chr. breaks
cases
1 265 190
2 268
 168
3 214
 128
4
 253
 141
5
 214
 121
6
 173
 83
7
 199 98
8
 184 76
9
 210 96
10 184 79
11 213 92
12 149
 62
13 197 73
14 132
 54
15 109
 43
16 103
 35
17 68 21
18 167 62
19 57 21
20 88 27
21 101
 31
22 83
 18
X 210
 119
Y 120
 40
SUMMARY 3961 1878


An Excel-file with more data on included cases (country where sample was derived from, gender, age, reason for studying) can be downloaded here.

set up using free programm https://seamonkey.at//start