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ChromosOmics - Database
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- mFISH - whole chromosome paints (wcps)
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OTHER
APPLICATIONS
mFISH with whole chromosome paints as probes is also
used with some modifications and tricks in research.
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Mutagenesis
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- Abo-Zeid MA, Liehr T,
El-Daly SM, Gamal-Eldeen AM, Glei M, Shabaka A,
Bhatt S, Hamid A (2013) Molecular cytogenetic
evaluation of the efficacy of photodynamic therapy
by Indocyanine Green in breast adenocarcinoma MCF-7
cells. Photodiagn Photodynam Therapy 10:194-202.
- Guda K, Upender MB,
Belinsky G, Flynn C, Nakanishi M, Marino JN, Ried T,
Rosenberg DW (2004) Carcinogen-induced colon tumors
in mice are chromosomally stable and are
characterized by low-level microsatellite
instability. Oncogene 23:3813-3821
- Kim YM, Yang S, Xu W, Li S,
Yang X (2008) Continuous in vitro exposure to
low-dose genistein induces genomic instability in
breast epithelial cells. Cancer Genet Cytogenet
186:78-84.
- Knutsen T, Rao VK, Ried T,
Mickley L, Schneider E, Miyake K, Ghadimi BM,
Padilla-Nash H, Pack S, Greenberger L, Cowan K, Dean
M, Fojo T, Bates S (2000) Amplification of 4q21-q22
and the MXR gene in independently derived
mitoxantrone-resistant cell lines. Genes Chromosomes
Cancer 27: 110-116.
- Komae N, Hibino Y, Sugano N
(1999) Analysis of micronuclei induced under
hyperthermic conditions in human lymphocyte culture
by fluorescence in situ hybridization (FISH) and
spectral karyotyping (SKY) methods. Yakugaku Zasshi
119: 763-772.
- Lacoste S, Wiechec E, Dos
Santos Silva AG, Guffei A, Williams G, Lowbeer M,
Benedek K, Henriksson M, Klein G, Mai S (2010)
Chromosomal rearrangements after ex vivo
Epstein-Barr virus (EBV) infection of human B cells.
Oncogene 29: 503-515.
- Loucas BD, Eberle RL,
Durante M, Cornforth MN (2004) Complex
chromatid-isochromatid exchanges following
irradiation with heavy ions? Cytogenet Genome Res
104: 206-210.
- Loucas BD, Eberle R, Bailey
SM, Cornforth MN (2004) Influence of dose rate on
the induction of simple and complex chromosome
exchanges by gamma rays. Radiat Res 162:339-349.
- McCormack SJ, Weaver Z,
Deming S, Natarajan G, Torri J, Johnson MD, Liyanage
M, Ried T, Dickson RB (1998) Myc/p53 interactions in
transgenic mouse mammary development, tumorigenesis
and chromosomal instability. Oncogene 16:2755-2766.
- Melcher R, von Golitschek
R, Steinlein C, Schindler D, Neitzel H, Kainer K,
Schmid M, Hoehn H (2000) Spectral karyotyping of
Werner syndrome fibroblast cultures. Cytogenet Cell
Genet 91: 180-185.
- Santiago F, Lima S,
Pinheiro T, Silvestre RT, Otero UB, Tabalipa MM,
Kosyakova N, Ornellas MH, Liehr T, Alves G. Benzene
poisoning, clinical and blood abnormalities in two
Brazilian female gas station attendants: two case
reports. BMC Res Notes. 2017,10:52.
- Samarth RM, Gandhi P,
Maudar KK (2013) A retrospective review of
cytogenetic studies on methyl isocyanate with
special reference to the Bhopal gas tragedy: is the
next generation also at risk? Int J Occup Med
Environ Health 26:324-336.
- Shen SX, Weaver Z, Xu X, Li
C, Weinstein M, Chen L, Guan XY, Ried T, Deng CX
(1998) A targeted disruption of the murine Brca1
gene causes gamma-irradiation hypersensitivity and
genetic instability. Oncogene 17: 3115-3124.
- Sumption ND, Goodhead DT,
Anderson RM (2006) No increase in radiation-induced
chromosome aberration complexity detected by m-FISH
after culture in the presence of
5'-bromodeoxyuridine. Mutat Res 594:30-38
- Wu H, Durante M, Furusawa
Y, George K, Kawata T, Cucinotta FA (2003) M-FISH
analysis of chromosome aberrations in human
fibroblasts exposed to energetic iron ions in vitro.
Adv Space Res 31:1537-1542
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Radiobiology |
- Anderson RM, Stevens DL,
Goodhead DT (2002) M-FISH analysis shows that
complex chromosome aberrations induced by
{alpha}-particle tracks are cumulative products of
localized rearrangements. Proc Natl Acad Sci U S A,
99: 12167-12172.
- Anderson RM, Sumption ND,
Papworth DG, Goodhead DT (2006) Chromosome
breakpoint distribution of damage induced in
peripheral blood lymphocytes by densely ionizing
radiation. Int J Radiat Biol 82:49-58
- Anderson RM, Papworth DG,
Stevens DL, Sumption ND, Goodhead DT (2006)
Increased complexity of radiation-induced chromosome
aberrations consistent with a mechanism of
sequential formation. Cytogenet Genome Res 112:
35-44.
- Balajee AS, Bertucci A,
Taveras M, Brenner DJ (2014) Multicolour FISH
analysis of ionising radiation induced micronucleus
formation in human lymphocytes. Mutagenesis 29:
447-455.
- Berardinelli F, De Vitis M,
Nieri D, Cherubini R, De Nadal V, Gerardi S,
Tanzarella C, Sgura A, Antoccia A (2015) mBAND and
mFISH analysis of chromosomal aberrations and
breakpoint distribution in chromosome 1 of AG01522
human fibroblasts that were exposed to radiation of
different qualities. Mutat Res Genet Toxicol Environ
Mutagen 793: 55-63.
- Braselmann H, Kulka U,
Baumgartner A, Eder C, Müller I, Figel M,
Zitzelsberger H (2005) SKY and FISH analysis of
radiation-induced chromosome aberrations: a
comparison of whole and partial genome analysis.
Mutat Res 578:124-133
- Desmaze C, Pirzio LM,
Blaise R, Mondello C, Giulotto E, Murnane JP,
Sabatier L (2004) Interstitial telomeric repeats are
not preferentially involved in radiation-induced
chromosome aberrations in human cells. Cytogenet
Genome Res 104:123-130.
- Eĭdel'man IuA, Slanina SV,
Sal'nikov IV, Andreev SG (2012) [Mechanistic
modelling allows to assess pathways of DNA lesion
interactions underlying chromosome aberration
formation]. Genetika 48:1427-1436. Russian
- Grandy I, Hardt T, Schmid
M, Haaf T (2002) Effects of higher-order nuclear
structure and Rad51 overexpression on
radiation-induced chromosome rearrangements.
Cytogenet Genome Res. 98: 265-269.
- Greulich KM, Kreja L,
Heinze B, Rhein AP, Weier HG, Bruckner M, Fuchs P,
Molls M (2000) Rapid detection of radiation-induced
chromosomal aberrations in lymphocytes and
hematopoietic progenitor cells by mFISH. Mutat Res
452: 73-81.
- Greulich-Bode KM,
Zimmermann F, Müller WU, Pakisch B, Molls M,
Würschmidt F (2012) Clinical, molecular- and
cytogenetic analysis of a case of severe
radio-sensitivity. Curr Genomics 13: 426-432.
- Hartel C, Nasonova E, Fuss
MC, Nikoghosyan AV, Debus J, Ritter S (2018)
Persistence of radiation-induced aberrations in
patients after radiotherapy with C-ions and IMRT.
Clin Transl Radiat Oncol 13:57-63.
- Hamasaki K, Kusunoki Y,
Nakashima E, Takahashi N, Nakachi K, Nakamura N,
Kodama Y (2009) Clonally expanded T lymphocytes from
atomic bomb survivors in vitro show no evidence of
cytogenetic instability. Radiat Res 172:234-243.
- Hande MP, Azizova TV, Burak
LE, Khokhryakov VF, Geard CR, Brenner DJ (2005)
Complex chromosome aberrations persist in
individuals many years after occupational exposure
to densely ionizing radiation: an mFISH study. Genes
Chromosomes Cancer 44: 1-9.
- Hieber L, Huber R, Bauer V,
Schäffner Q, Braselmann H, Thomas G, Bogdanova T,
Zitzelsberger H (2011) Chromosomal rearrangements in
post-Chernobyl papillary thyroid carcinomas:
evaluation by spectral karyotyping and automated
interphase FISH. J Biomed Biotechnol 2011:693691.
- Hu B, Zhu J, Zhou H, Hei TK
(2013) No significant level of inheritable
interchromosomal aberrations in the progeny of
bystander primary human fibroblast after alpha
particle irradiation. Adv Space Res 51:450-457.
- Kuechler A, Neubauer S,
Grabenbauer GG, Claussen U, Liehr T, Sauer R, Wendt
TG (2002) Is 24-color FISH detection of in-vitro
radiation-induced chromosomal aberrations suited to
determine individual intrinsic radiosensitivity?
Strahlenther Onkol 178: 209-215.
- Livingston GK, Escalona M,
Foster A, Balajee AS (2018) Persistent in vivo
cytogenetic effects of radioiodine therapy: a
21-year follow-up study using multicolor FISH. J
Radiat Res 21: 1-8.
- Loucas BD, Durante M,
Bailey SM, Cornforth MN (2013) Chromosome damage in
human cells by γ rays, α particles and heavy ions:
track interactions in basic dose-response
relationships. Radiat Res 179:9-20.
- Loucas BD (2019)
Analysis of radiation-induced chromosome exchanges
using combinatorial chromosome painting. Methods Mol
Biol 1984:123-135.
- Loucas BD, Cornforth MN
(2013) The LET dependence of unrepaired chromosome
damage in human cells: a break too far? Radiat Res
179:393-405.
- Martín M, Terradas M,
Hernández L, Genescà A (2014) γH2AX foci on
apparently intact mitotic chromosomes: not
signatures of misrejoining events but signals of
unresolved DNA damage. Cell Cycle 13: 3026-3036.
- Nieri D, Berardinelli F,
Sgura A, Cherubini R, De Nadal V, Gerardi S,
Tanzarella C, Antoccia A (2013) Cyogenetics effects
in AG01522 human primary fibroblasts exposed to low
doses of radiations with different quality. Int J
Radiat Biol 89:698-707.
- Nieri D, Berardinelli F,
Antoccia A, Tanzarella C, Sgura A (2013) Comparison
between two FISH techniques in the in vitro study of
cytogenetic markers for low-dose X-ray exposure in
human primary fibroblasts. Front Genet 4:141.
- Polityko A, Khurs O,
Rumyantseva N, Naumchik I, Kosyakova N, Tönnies H,
Sperling K, Neitzel H, Weise A, Liehr T (2010) Two
siblings with immunodeficiency, facial abnormalities
and chromosomal instability without mutation in
DNMT3B gene but liability towards malignancy; a new
chromatin disorder delineation? Mol Cytogenet 3:5
- Ponnaiya B, Suzuki M,
Tsuruoka C, Uchihori Y, Wei Y, Hei TK (2011)
Detection of chromosomal instability in bystander
cells after Si490-ion irradiation. Radiat Res
176:280-290.
- Pouzoulet F, Roch-Lefèvre
S, Giraudet AL, Vaurijoux A, Voisin P, Buard V,
Delbos M, Bourhis J, Voisin P, Roy L (2007)
Monitoring translocations by M-FISH and three-color
FISH painting techniques: a study of two
radiotherapy patients. J Radiat Res (Tokyo)
48:425-434
- Rithidech KN, Honikel LM,
Reungpatthanaphong P, Tungjai M, Golightly M,
Whorton EB (2013) Effects of 100MeV protons
delivered at 0.5 or 1cGy/min on the in vivo
induction of early and delayed chromosomal damage.
Mutat Res 756:127-140.
- Schmitz S, Pinkawa M, Eble
MJ, Kriehuber R (2013) Persisting ring chromosomes
detected by mFISH in lymphocytes of a cancer
patient-a case report. Mutat Res 756:158-164.
- Shim G, Normil MD, Testard
I, Hempel WM, Ricoul M, Sabatier L (2016) Comparison
of individual radiosensitivity to γ-rays and carbon
ions. Front Oncol 6: 137.
- Szeles A, Joussineau S,
Lewensohn R, Lagercrantz S, Larsson C (2006)
Evaluation of spectral karyotyping (SKY) in
biodosimetry for the triage situation following
gamma irradiation. Int J Radiat Biol 82:87-96
- Zitzelsberger H, Lehmann L,
Hieber L, Weier HU, Janish C, Fung J, Negele T,
Spelsberg F, Lengfelder E, Demidchik EP, Salassidis
K, Kellerer AM, Werner M, Bauchinger M (1999)
Cytogenetic changes in radiation-induced tumors of
the thyroid. Cancer Res 59: 135-140.
- Zitzelsberger H, Fung J,
Janish C, McNamara G, Bryant PE, Riches AC, Weier
HUG (1999) Spectral karyotyping (SKY) analysis of
heritable effects of radiation-induced malignant
transformation. SPIE Proc. 3605: 325-331.
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linkage/mapping
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- Brink AA, Wiegant JC,
Szuhai K, Tanke HJ, Kenter GG, Fleuren GJ, Schuuring
E, Raap AK (2002) Simultaneous mapping of human
papillomavirus integration sites and molecular
karyotyping in short-term cultures of cervical
carcinomas by using 49-color combined binary ratio
labeling fluorescence in situ hybridization.Cancer
Genet Cytogenet 134: 145-150.
- Dunham I, Braden VV,
Hilgenfeld E, Schuler G, Lash AE, Shen GL, Martelli
M, Kuehl WM, Klausner RD, Ried T (2000) A
systematic, high-resolution linkage of the
cytogenetic and physical maps of the human genome.
Nat Genet 24: 339-340.
- Ye CJ, Lu W, Liu G, Bremer
SW, Wang YA, Moens P, Hughes M, Krawetz SA, Heng HHQ
(2001) The combination of SKY and specific loci
detection with FISH or immunostaining. Cytogenet
Cell Genet 93: 195-202.
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Interphase archtiecture
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- Cornforth MN, Greulich-Bode
KM, Loucas BD, Arsuaga J, Vazquez M, Sachs RK,
Bruckner M, Molls M, Hahnfeldt P, Hlatky L, Brenner DJ
(2002) Chromosomes are predominantly located randomly
with respect to each other in interphase human cells.
J Cell Biol 159: 237-244.
- Cremer T, Cremer C (2001)
Chromosome territories, nuclear architecture and gene
regulation in mammalian cells. Nat Rev Genet 2:
292-301.
- Cremer M, Müller S, Solovei
I, Cremer T (2008) 3D-fluorescent in situ
hybridization and nuclear architecture. Medgen 20:
379-385 (German)
- Cremer M, Grasser F, Lanctôt
C, Müller S, Neusser M, Zinner R, Solovei I, Cremer T
(2008) Multicolor 3D fluorescence in situ
hybridization for imaging interphase chromosomes.
Methods Mol Biol 463:205-239.
- Dietzel S, Eils R, Satzler K,
Bornfleth H, Jauch A, Cremer C, Cremer T (1998)
Evidence against a looped structure of the inactive
human X-chromosome territory. Exp Cell Res 240:
187-196.
- Geigl JB, Uhrig S, Speicher
MR (2006) Multiplex-fluorescence in situ hybridization
for chromosome karyotyping. Nat Protoc 1:1172-1184.
- Hovhannisyan G, Aroutiounian
R, Babayan N, Harutyunyan T, Liehr T (2016)
Comparative analysis of individual chromosome
involvement in micronuclei induced by mitomycin C and
bleomycin in human leukocytes. Mol Cytogenet 9: 49.
- Su JH, Zheng P, Kinrot SS,
Bintu B, Zhuang X (2020) Genome-Scale imaging of the
3D organization and transcriptional activity of chromatin.
Cell 182:1641-1659.e26.
- Walter J, Joffe B, Bolzer A,
Albiez H, Benedetti PA, Muller S, Speicher MR, Cremer
T, Cremer M, Solovei I (2006) Towards many colors in
FISH on 3D-preserved interphase nuclei. Cytogenet
Genome Res 114:367-378.
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mFISH and immunohistochemistry
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- Horsley SW, Colman S,
McKinley M, Bateman CM, Jenney M, Chaplin T, Young
BD, Greaves M, Kearney L (2008) Genetic lesions in a
preleukemic aplasia phase in a child with acute
lymphoblastic leukemia. Genes Chromosomes Cancer
47:333-340.
- Ye CJ, Lu W, Liu G, Bremer
SW, Wang YA, Moens P, Hughes M, Krawetz SA, Heng HHQ
(2001) The combination of SKY and specific loci
detection with FISh or immunostaining. Cytogenet
Cell Genet 93: 195-202.
- Ye CJ, Stevens JB, Liu G,
Ye KJ, Yang F, Bremer SW, Heng HH (2006) Combined
multicolor-FISH and immunostaining. Cytogenet Genome
Res 114:227-234.
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Zoo-FISH |
- Best RG, Diamond D,
Crawford E, Grass FS, Janish C, Lear TL, Soenksen D,
Szalay AA, Moore CM (1998) Baboon/human homologies
examined by spectral karyotyping (SKY): a visual
comparison. Cytogenet Cell Genet 82: 83-87.
- Xiaobo F, Pinthong K,
Mkrtchyan H, Siripiyasing P, Kosyakova N, Supiwong
W, Tanomtong A, Chaveerach A, Liehr T, de Bello
Cioffi M, Weise A (2013) First detailed
reconstruction of the karyotype of Trachypithecus
cristatus (Mammalia: Cercopithecidae). Mol Cytogenet
6:58.
- Fatyol K, Illes K, Diamond
DC, Janish C, Szalay AA (2000) Mer22-related
sequence elements form pericentric repetitive DNA
families in primates. Mol Gen Genet 262: 931-939.
- de Oliveira EH, Neusser M,
Pieczarka JC, Nagamachi C, Sbalqueiro IJ, Muller S
(2005) Phylogenetic inferences of Atelinae
(Platyrrhini) based on multi-directional chromosome
painting in Brachyteles arachnoides, Ateles paniscus
paniscus and Ateles b. marginatus. Cytogenet Genome
Res 108: 183-190.
- Moore CM, Janish C, Eddy
CA, Hubbard GB, Leland MM, Rogers J (1999)
Cytogenetic and fertility studies of a rheboon,
rhesus macaque (Macaca mulatta) x baboon (Papio
hamadryas) cross: further support for a single
karyotype nomenclature. Am J Phys Anthropol 110:
119-127.
- Mrasek K, Heller A, Rubtsov
N, Trifonov V, Starke H, Rocchi M, Claussen U, Liehr
T (2001) Reconstruction of the female Gorilla
gorilla karyotype by Zoo-FISH using 25-color FISH
and multicolor banding (MCB). Cytogenet Cell Genet
93: 242-248.
- Mrasek K, Heller A, Rubtsov
N, Trifonov V, Starke H, Claussen U, Liehr T (2003)
Detailed Hylobates lar karyotype defined by 25-color
FISH and multicolor banding. Int J Mol Med 12:
139-146.
- Neusser M, Stanyon R,
Bigoni F, Wienberg J, Müller S (2001) Molecular
cytotaxonomy of New World monkeys (Platyrrhini) --
comparative analysis of five species by multi-color
chromosome painting gives evidence for a
classification of Callimico goeldii within the
family of Callitrichidae. Cytogenet Cell Genet 94:
206-215.
- Neusser M, Munch M,
Anzenberger G, Muller S (2005) Investigation of
marmoset hybrids (Cebuella pygmaea x Callithrix
jacchus) and related Callitrichinae (Platyrrhini) by
cross-species chromosome painting and comparative
genomic hybridization. Cytogenet Genome Res 108:
191-196.
- Nie W, Rens W, Wang J, Yang
F (2001) Conserved chromosome segments in Hylobates
hoolock revealed by human and H. leucogenys paint
probes.Cytogenet Cell Genet 92: 248-253.
- Rens W, Yang F, O'Brien PC,
Solanky N, Ferguson-Smith MA (2001) A classification
efficiency test of spectral karyotyping and
multiplex fluorescence in situ hybridization:
Identification of chromosome homologies between Homo
sapiens and Hylobates leucogenys. Genes Chr Cancer
31: 65-74.
- Sangpakdee W, Tanomtong A,
Fan X, Pinthong K, Weise A, Liehr T (2016)
Application of multicolor banding combined with
heterochromatic and locus-specific probes identify
evolutionary conserved breakpoints in Hylobates
pileatus. Mol Cytogenet 9: 17.
- Sangpakdee W, Tanomtong A,
Chaveerach A, Pinthong K, Trifonov V, Loth K, Hensel
C, Liehr T, Weise A, Fan X (2018) Molecular
cytogenetic analysis of one African and five Asian
macaque species reveals identical karyotypes as in
mandrill. Curr Genomics 19:207-215.
- Sangpakdee W, Phimphan S,
Liehr T, Fan X, Pinthong K, Patawang I, Tanomtong A
(2016) Characterization of chromosomal
rearrangements in pileated gibbon (Hylobates
pileatus) using multiplex-FISH technique. The
Nucleus 59: 131-135.
- Schröck E, du Manoir S,
Veldman T, Schoell B, Wienberg J, Ferguson-Smith MA,
Ning Y, Ledbetter DH, Bar-Am I, Soenksen D, Garini
Y, Ried T (1996) Multicolor spectral karyotyping of
human chromosomes. Science, 273:494-497.
- Schröck E, Zschieschang P,
O'Brien P, Helmrich A, Hardt T, Matthaei A,
Stout-Weider K (2006) Spectral karyotyping of human,
mouse, rat and ape chromosomes--applications for
genetic diagnostics and research. Cytogenet Genome
Res 114:199-221.
- Stanyon R, Bruening R,
Stone G, Shearin A, Bigoni F (2005) Reciprocal
painting between humans, De Brazza's and patas
monkeys reveals a major bifurcation in the
Cercopithecini phylogenetic tree. Cytogenet Genome
Res 108: 175-182.
- Weise A, Kosyakova N, Voigt
M, Aust N, Mrasek K, Löhmer S, Rubtsov N,
Karamysheva T, Trifonov V, Hardekopf D, Jancuková ,
Pekova S, Wilhelm K, Liehr T, Fan X (2015)
Comprehensive analyses of white handed gibbon
chromosomes enables access to 92 evolutionary
conserved breakpoints compared to the human genome.
Cytogenet Genome Res 145:42-49.
- Wienberg J, Stanyon R
(1997) Comparative painting of mammalian
chromosomes. Curr Opin Genet Dev 7: 784-791.
- Wienberg J (2005)
Fluorescence in situ hybridization to chromosomes as
a tool to understand human and primate genome
evolution. Cytogenet Genome Res 108:139-160.
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FISH-midi or FISH-MD
(microdissection)
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- Roberts I, Foster N,
Nacheva E, Coleman N (2004) Paint-assisted
microdissection-FISH: Rapid and simple mapping of
translocation breakpoints in the embryonal
rhabdomyosarcoma cell line RD. Cytometry A
58:177-184
- Weimer J, Kiechle M, Arnold
N (2000) FISH-microdissection (FISH-MD) analysis of
complex chromosome rearrangements. Cytogenet Cell
Genet 88: 114-118.
- Weimer J, Koehler MR,
Wiedemann U, Attermeyer P, Jacobsen A, Karow D,
Kiechl M, Jonat W, Arnold N (2001) Highly
comprehensive karyotype analysis by a combination of
spectral karyotyping (SKY), microdissection, and
reverse painting (SKY-MD). Chromosome Res 9:
395-402.
- Weimer J, Cohen M,
Wiedemann U, Heinrich U, Jonat W, Arnold N (2006)
Proof of partial imbalances 6q and 11q due to
maternal complex balanced translocation analyzed by
microdissection of multicolor labeled chromosomes
(FISH-MD) in a patient with Dandy-Walker variant.
Cytogenet Genome Res 114: 235-239.
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Alternatives to mFISH with
human wcps
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- Ji Z, Zhang L (2012)
Chromosomics: detection of numerical and structural
alterations in all 24 human chromosomes
simultaneously using a novel OctoChrome FISH assay.
J Vis Exp. 2012 Feb 6;(60).
- Joyce CA, Ross FM, Dennis
NR, Wyre ND, Barber JC (1999) Multipaint FISH: a
rapid and reliable way to define cryptic and complex
abnormalities. Clin Genet 56: 192-199.
- Ogilvie CM, Shemilt S,
Davies AF, Weber-Hall S, Chuang C, Sundaresan V
(2000) Characterization of a chromosomally complex
lung cancer cell line using multiwell fluorescence
in situ hybridization. Cancer Genet Cytogenet 117:
149-152.
- Roberts I, Wienberg J,
Nacheva E, Grace C, Griffin D, Coleman N (1999)
Novel method for the production of multiple colour
chromosome paints for use in karyotyping by
fluorescence in situ hybridisation. Genes Chr Cancer
25: 241-250.
- Zhang L, Lan Q, Guo W,
Hubbard AE, Li G, Rappaport SM, McHale CM, Shen M,
Ji Z, Vermeulen R, Yin S, Rothman N, Smith MT (2011)
Chromosome-wide aneuploidy study (CWAS) in workers
exposed to an established leukemogen, benzene.
Carcinogenesis 32:605-612.
- Zhang L, Lan Q, Guo W, Li
G, Yang W, Hubbard AE, Vermeulen R, Rappaport SM,
Yin S, Rothman N, Smith MT (2005) Use of OctoChrome
fluorescence in situ hybridization to detect
specific aneuploidy among all 24 chromosomes in
benzene-exposed workers. Chem Biol Interact
153-154:117-122.
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