clinical symptoms

In general 70% of sSMC carriers are clinically normal. The figures listed above
are based on the bias, that mainly clinically aberrant cases are studied and reported in literature!

UPD (uniparental disomy) cases:

UPD(11)mat

UPD(11)pat

UPD(11)mat or pat

the probably non-dosage sensitive pericentric region of chromosome 11
schematic cytogenetic depiction	short (= p-) arm het long (= q-) arm p14 p13 p12 p11 cen q12 q13 no clinical signs clinical signs
schematic molecular- cytogenetic depiction	Data is converted between genome versions by UCSC browser! Note the changes defined there for centromere-sizes; due to that and due to 'new insertions and deletions', positions are not always seeming logical comparing different versions listed  genomic version critical region p-arm uncritical region p-arm centromere uncritical region q-arm critical region q-arm NCBI 36/ hg18 42.88 48.26 51.40 - 56.40 60.23 78.05 GRCh 37/ hg19 42.92 48.30 51.60 - 55.70 60.47 79.07 GRCh 38/ hg38 42.90 48.28 51.00 - 53.40 60.71 79.36   Positions given in megabasepair (Mbp) acc. to cases marked as *** Acc. to {47} triplosensitive regions start between postions (hg19) of 45,048,321 to 47,675,469 and 60,516,539 to 61,479,322, respectively