TL

ChromosOmics - Database

- CHROMOSOME 11 -
- paternal UPD -

UPD MATERNAL CHR . 11	UPD unclear if maternal or paternal CHR . 11
UPD-cases without clinical findings + normal karyotype	UPD-cases with or unclear clinical correlation + normal karyotype
UPD-cases without clinical findings + balanced karyotype	UPD-cases with or unclear clinical correlation + balanced karyotype
UPD-cases without clinical findings + sSMC	UPD-cases with or unclear clinical correlation + sSMC
segmental UPD-cases without clinical findings	segmental UPD-cases with or unclear clinical correlation
UPD-cases without clinical findings + other imbalances	UPD-cases with or unclear clinical correlation + other imbalances
References

pat UPD-cases without clinical findings + normal karyotype

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-N/ 1-1	-	-	-	-	-	-

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-N/ mos/ 1-1	-	-	-	-	-	-

pat UPD-cases without clinical findings + balanced karyotype

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-bal/ 1-1	-	-	-	-	-	-

pat UPD-cases without clinical findings + sSMC

case no.	case no. in sSMC database	gender/ age at diagnosis	studied material	GTG-banding result	final FISH result of the sSMC	FISH methods	clinical symptoms	reference
11- OpU-sSMC/ 1-1	-	-	-	-	-	-	-	-

segmental pat UPD-cases without clinical findings

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-seg/ p15.4/ 1-1 to 1-2	female	32 to 35 y	PBL	n.a. --- pat UPD 11 in 11p15.4 (gene TH01)	normal females but infertile due to partial or complete hydatic mole	{1145}
11- OpU-seg/ p15.4/ 1-3	female	~32 y	PBL	n.a. --- pat UPD 11 in 11p15.4 (gene TH01)	normal female with gestational trophoblastic neoplasia but infertile due to partial or complete hydatic mole	{1145}

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-seg/ / mos/ 1-3	-	-	-	-	-	-

pat UPD-cases without clinical findings + other imbalances

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-imb/ 1-1	-	-	-	-	-	-

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- OpU-imb/ mos/ 1-1	-	-	-	-	-	-

pat UPD-cases with or unclear clinical correlation + normal karyotype

review on BWS see {835}; in BWS due to UPD(11)pat developing hyperinsulinaemic hypoglycaemia
require near-total pancreatectomy - maybe sirolimus treatment may help as well {939}
Also enhanced cancer risk in BWS-patients in general and specifically in such with UPD(11)pat {1233}
Acc. to {1279} all BWS cases diseased due to UPD are mosaics.
For general review on BWS see also {1382 and 1383}.
Acc. to {1594} BWS patients with UPD(11)pat having narrower mouths while imprinting center loss lads to wider tongues and mouths.
{1600} state that BWS patient with UPD(11)pat have higher reoperation rates of macroglossia than others.

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-N/ 1-1 to 1-14	n.a.	postnatal	PBL	n.a.	Beckwith-Wiedemann-syndrome (BWS)	{129}
11- WpU-N/ 1-15 to 1-18	n.a.	postnatal	PBL	n.a.	BWS	{139} cases 49-52 {140}
11- WpU-N/ 1-19	n.a.	postnatal	PBL	n.a.	BWS	{285}
11- WpU-N/ 1-20	n.a.	postnatal	PBL	n.a.	BWS	{610} 1 case
11- WpU-N/ 1-21	male	postnatal	PBL	n.a.	BWS (and hepatoblastoma)	{616}
11- WpU-N/ 1-22 to 1-23	n.a.	postnatal	PBL	n.a.	BWS	{638}
11- WpU-N/ 1-24 to 1-119	n.a.	postnatal	PBL	n.a.	BWS	{640} 96 cases; in {679} 41 of those cases
11- WpU-N/ 1-120 to 1-131	n.a.	postnatal	PBL	n.a.	BWS	{654; 672} 11 cases
11- WpU-N/ 1-132 to 185	n.a.	postnatal	PBL	n.a.	BWS	{672; 674} 54 cases
11- WpU-N/ 1-186 to 1-188	n.a.	postnatal	PBL	n.a.	BWS	{766} cases 2 to 4
11- WpU-N/ 1-189 to 1-269	n.a.	postnatal	PBL	n.a. unclear if segmental!!	BWS	{780} 81 cases
11- WpU-N/ 1-270	n.a.	postnatal	PBL	n.a.	BWS	{804} 1 case
11- WpU-N/ 1-271	n.a.	postnatal	PBL	n.a.	BWS	{808}
11- WpU-N/ 1-272 to 1-406	n.a.	postnatal	PBL	n.a.	BWS	{835} 135 cases
11- WpU-N/ 1-407	n.a.	postnatal	PBL	n.a.	BWS	{843} 1 case
11- WpU-N/ 1-408 to 1-430	n.a.	postnatal	PBL	n.a.	BWS	{654; 672; 674; 871;943} 22 cases
11- WpU-N/ 1-431 to 1-442	n.a.	postnatal	PBL	n.a.	BWS	{881} 12 cases
11- WpU-N/ 1-443	n.a.	postnatal	PBL	n.a.	BWS	{889} 1 case
11- WpU-N/ 1-444 to 1-452	n.a.	postnatal	PBL	n.a.	BWS	{969} 9 cases
11- WpU-N/ 1-453 to 1-454	n.a.	postnatal	PBL	n.a.	BWS	{985} 2 cases
11- WpU-N/ 1-455 to 1-456	n.a.	prenatal	AF	n.a.	BWS	{1098} 2 cases
11- WpU-N/ 1-457	n.a.	newborn	PBL	n.a.	BWS	{1123}
11- WpU-N/ 1-458	n.a.	child	PBL	n.a.	BWS	{1205} 1 case
11- WpU-N/ 1-459	n.a.	child	PBL	n.a.	BWS	{1250} 1 case
11- WpU-N/ 1-460 to 1-497	n.a.	postnatal	PBL	n.a.	BWS	{1270; 1271} overall 38 cases
11- WpU-N/ 1-498 to 1-505	n.a.	postnatal	PBL	n.a.	BWS	{1292} 8 cases
11- WpU-N/ 1-506 to 1-507	n.a.	postnatal	PBL	n.a.	BWS	{1353} cases 1 to 2
11- WpU-N/ 1-508 to 1-517	n.a.	postnatal	PBL	n.a.	BWS	{1355} 10 cases
11- WpU-N/ 1-518 to 1-529	n.a.	postnatal	PBL	n.a.	BWS	{1360} 12 cases
11- WpU-N/ 1-530	female	postnatal	PBL	n.a.	BWS	{1388}, case 1
11- WpU-N/ 1-531 to 1-541	n.a.	postnatal	PBL	n.a.	BWS	{1413} 11 cases
11- WpU-N/ 1-542	female	4m	PBL	n.a.	BWS	{1430}
11- WpU-N/ 1-543	male	1y	PBL	n.a.	BWS and Wilms tumor	{1467}
11- WpU-N/ 1-544	n.a.	postnatal	PBL	n.a.	BWS and Wilms tumor	{1475}
11- WpU-N/ 1-545 to 1-558	10 male 3 female	postnatal	PBL	n.a.	BWS	{1527} 13 cases
11- WpU-N/ 1-559	female	prenatal	AF	46,XY	BWS; TOP	{1528} case 25
11- WpU-N/ 1-560 to 1-562	n.a.	postnatal	PBL	n.a.	BWS	{1580} 3 cases
11- WpU-N/ 1-563 to 1-577	n.a.	postnatal	PBL	n.a.	BWS	{1594} 15 cases
11- WpU-N/ 1-578 to 1-581	n.a.	postnatal	PBL	n.a.	BWS	{1600} 4 cases
11- WpU-N/ 1-582 to 1-617	n.a.	postnatal	PBL	n.a.	BWS	{1605} 36 cases
11- WpU-N/ 2-1	male	postnatal	PBL	n.a.	focal BWS and ß-thalassemia (gene HBB in 11p15.4)	{84}
11- WpU-N/ 3-1 to 3-4	n.a.	postnatal	PBL	46,XN UPD only proven for band 11p15	focal form of neonatal hyperinsulinism (gene ABCC8 in 11p15.1)	{146} 4 cases
11- WpU-N/ 4-1 to 5-2	n.a.	postnatal	PBL, tongue	n.a. UPD11 only in tongue not in blood detected	BWS	{794} 2 cases
11- WpU-N/ 5-1 to 5-4	n.a.	postnatal	PBL	n.a.	BWS	{947} cases 17, 128, 220, 227b}
11- WpU-N/ 6-2 to 6-3	n.a.	newborn	PBL	46,XN UPD only proven for band 11p15 and mosaic	BWS and congenital hyperinsulinism and hemihypertrophy (gene KCNJ11 in 11p15.1)	{1386} cases 8 and 9
11- WpU-N/ 7-1 to 7-4	n.a.	postnatal, children	PBL	n.a.	no BWS but Cushing syndrome in one of 4 and all with adrenocortical tumors	{1353} cases 3-6

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-N/ mos/ 1-1 to 1-2	n.a.	postnatal	PBL	n.a. UPD in mosaic - not specified	BWS	{1304} 2 cases
11- WpU-N/ mos/ 1-3	female	postnatal	PBL	46,XX acc to mol. genet. result mosaic of cells with and without pat UPD	BWS	{157} case 3
11- WpU-N/ mos/ 1-4	female	postnatal	PBL; different tissues	n.a. acc to mol. genet. result mosaic of cells with and without pat UPD	BWS	{224}
11- WpU-N/ mos/ 1-5 to 1-6	n.a.	postnatal	PBL	n.a. 10-20% only with UPD	BWS	{713} cases KvDMR and H19DMR
11- WpU-N/ mos/ 1-7	female	postnatal	PBL	n.a. 90% only with UPD	BWS	{935} case 21-006
11- WpU-N/ mos/ 1-8 to 1-13	n.a.	postnatal	PBL	n.a. mosaic of UPD	BWS	{955} cases 10-14; 25
11- WpU-N/ mos/ 1-14	female	5m	PBL	n.a. mosaic of UPD 11 only 11p15.5 region tested	BWS	{1117}
11- WpU-N/ mos/ 1-15	n.a.	newborn	PBL	n.a. mosaic of UPD 11 only 11p15.5 region tested	BWS	{1150}
11- WpU-N/ mos/ 1-16	n.a.	newborn	PBL	n.a. mosaic of UPD 11 only 11p15.5 region tested	BWS	{1339} 1 case
11- WpU-N/ mos/ 1-17 to 1-28	n.a.	postnatal after IVF	PBL	n.a. mosaic of UPD 11 unclear which region tested	BWS	{1406} 12 cases
11- WpU-N/ mos/ 1-29 to 1-33	n.a.	postnatal	PBL	n.a. mosaic of UPD 11 unclear which region tested	BWS	{1440} 5 cases
11- WpU-N/ mos/ 1-34	female	2m	PBL	n.a. mosaic of UPD 11 unclear which region tested	BWS	{1491}
11- WpU-N/ 2-1 to 2-5	n.a.	postnatal	PBL	46,XN UPD only proven for band 11p15 and mosaic	focal form of neonatal hyperinsulinism (gene ABCC8 in 11p15.1)	{1386} cases 1-5
11- WpU-N/ 3-1 to 3-2	n.a.	newborn	PBL	46,XN UPD only proven for band 11p15 and mosaic	BWS and congenital hyperinsulinism and hemihypertrophy (gene KCNJ11 in 11p15.1)	{1386} cases 8 and 9

pat UPD-cases with or unclear clinical correlation+ balanced karyotype

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-bal/ 1-1	-	-	-	-	-	-

pat UPD-cases with or unclear clinical findings + sSMC

case no.	case no. in sSMC database	gender/ age at diagnosis	studied material	GTG-banding result	final FISH result of the sSMC	FISH methods	clinical symptoms	reference
11- WpU-sSMC/ 1-1	-	-	-	-	-	-	-	-

segmental pat UPD-cases with or unclear clinical correlation

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-seg/ 1-1 to 10	n.a.	postnatal	PBL	n.a. --- pat UPD 11 in LIT tested	BWS	{579} 6 cases from 'validation group' and 4 from 'practice group'
11- WpU-seg/ 1-11 to 1-18	n.a.	postnatal	PBL	n.a. --- pat UPD 11 (at least in 11p15)	BWS	{798} 8 cases
11- WpU-seg/ 1-19	female	1m	PBL	n.a. --- pat UPD 11 (at least in 11p15)	BWS	{939}
11- WpU-seg/ pter/ 1-1 to 1-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.5	BWS	{139} cases 1-2 {140}
11- WpU- seg-pter/ 1-3 to 1-4	n.a.	postnatal	PBL	46,XN --- 11pter to 11p15.5	BWS	{609} cases 6-7
11- WpU-seg/ pter/ 1-5	female	16y	PBL and fibroa-denoma	n.a. --- 11pter to 11p15.5	BWS	{861}
11- WpU-seg/ pter/ 1-6 to 1-7	n.a.	postnatal	n.a.	n.a. --- 11pter to 11p15.5	BWS after ART	{1012} 2 cases
11- WpU-seg/ pter/ 1-8	n.a.	postnatal	PBL; hepato-blastoma	n.a. --- 11pter to 11p15.5	BWS	{1030}
11- WpU-seg/ pter/ 2-1 to 1-12	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.4	BWS	{139} cases 3-14 {140}
11- WpU-seg/ pter/ 3-1 to 3-5	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.1	BWS	{139} cases 15-19 {140}
11- WpU-seg/ pter/ 4-1 to 4-2	2 female	prenatal	AF	46,XX --- 11pter to 11p15	BWS; omphalocoele, TOP	{195} 2 cases
11- WpU-seg/ pter/ 5-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14.3	ß-thalassemia major evolution from ß-thalassemia minor (gene HBB in 11p15.4)	{498}
11- WpU-seg/ pter/ 6-1 to 6-8	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14	BWS	{139} cases 20-27 {140}
11- WpU-seg/ pter/ 6-9 to 6-12	n.a.	postnatal	PBL	46 --- 11pter to 11p14	BWS, Wilmstumor	{208} 4 cases {209} 2 cases
11- WpU-seg/ pter/ 6-13	male	postnatal	PBL	46,XY --- 11pter to 11p14	BWS; permanent neonatal diabetes, hemihypertrophy (gene ABCC8 in 15p15.1)	{325}
11- WpU-seg/ pter/ 6-14	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14	BWS	{348} family 5 {351; 349}
11- WpU-seg/ pter/ 6-15	n.a.	postnatal	PBL	46,XN --- 11pter to 11p14	BWS	{609} case 8
11- WpU-seg/ pter/ 6-16	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14	BWS	{619} case 37
11- WpU-seg/ pter/ 7-1	male	newborn	PBL	46,XY --- 11pter to 11p14~13	BWS	{106}
11- WpU-seg/ pter/ 8-1 to 8-8	n.a.	postnatal	PBL	n.a. --- 11pter to 11p13	BWS	{139} cases 28-35 {140}
11- WpU-seg/ pter/ 8-9 to 8-14	3 male, 3 female	postnatal	PBL	46,XX or 46,XY --- 11pter to 11p13	BWS	{157} cases 1-2 and 4-7
11- WpU-seg/ pter/ 8-15	n.a.	postnatal	PBL	46,XN --- 11pter to 11p13	BWS	{609} case 5
11- WpU-seg/ pter/ 9-1	n.a.	postnatal	PBL	46,XN --- 11pter to 11p12	BWS	{609} case 3
11- WpU-seg/ pter/ 10-1	n.a.	newborn	PBL	n.a. --- 11pter to 11p11	BWS, Wilmstumor	{397}
11- WpU-seg/ pter/ 11-1 to 11-13	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11	BWS	{139} cases 36-48 {140}
11- WpU-seg/ pter/ 12-1 to 12-4	n.a.	postnatal	PBL	46,XN --- 11pter to 11p11.2	BWS	{609} cases 1, 2, 4, 9
11- WpU-seg/ pter/ 2-1	male	5m	PBL	n.a. --- 11pter to 11p11.1	no BWS but Cushing syndrome	{1317}
11- WpU-seg/ p15/ 3-1 to 3-2	n.a.	postnatal	PBL	n.a. --- 11p15	ß-thalassemia major evolution from ß-thalassemia minor (gene HBB in 11p15.4)	{549; 716} two families
11- WpU-seg/ p15/ 4-1	n.a.	postnatal	PBL	n.a. --- 11p15-11p15	BWS	{766} case 1

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-seg/ mos/ 1-1 to 1-10	n.a.	postnatal	PBL	n.a. --- pat UPD 11 in LIT tested in mosaic	BWS	{579} 10 cases from 'practice group'
11- WpU-seg/ mos/ 1-11 to 1-38	17 female 11 male	postnatal	PBL	n.a. --- seg. pat UPD 11 in mosaic	BWS	{935} 28 cases
11- WpU-seg/ mos/ 1-39 to 1-70	17 female 11 male	postnatal	PBL	n.a. --- seg. pat UPD 11 in mosaic	BWS	{1363} 32 cases
11- WpU-seg/ pter/ mos/ 1-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.5 mosaic 50%	BWS	{782} case 4
11- WpU-seg/ pter/ mos/ 1-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.5 mosaic 16%	BWS	{782} case 7
11- WpU-seg/ pter/ mos/ 2-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.4 mosaic 24%	BWS	{782} case 12
11- WpU-seg/ pter/ mos/ 2-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.4 mosaic 25%	BWS	{782} case 14
11- WpU-seg/ pter/ mos/ 2-3	n.a.	postnatal	PBL tongue	n.a. --- 11pter to 11p15.4 mosaic 47% and 27%	BWS	{782} case 16
11- WpU-seg/ pter/ mos/ 2-4	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.4 mosaic	BWS	{903} 1 case
11- WpU-seg/ pter/ mos/ 2-5 to 2-7	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.4 mosaic	BWS	{955} cases 15, 21, 22
11- WpU-seg/ pter/ mos/ 3-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.3 mosaic	BWS	{955} case 16
11- WpU-seg/ pter/ mos/ 4-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.2 in mosaic 39%	BWS	{782} case 8
11- WpU-seg/ pter/ mos/ 4-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.2 in mosaic ?%	BWS	{828; 1170} 1 case
11- WpU-seg/ pter/ mos/ 4-3 to 4-4	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.2 in mosaic 50%	BWS	{955} cases 1, 17
11- WpU-seg/ pter/ mos/ 5-1	female	postnatal	PBL	n.a. --- 11pter to 11p15.1 in mosaic	BWS (less expressed)	{221; 555}
11- WpU-seg/ pter/ mos/ 5-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.1 in mosaic	focal form of neonatal hyperinsulinism (gene ABCC8 in 11p15.1)	{726}
11- WpU-seg/ pter/ mos/ 5-3	n.a.	postnatal	PBL	n.a. --- 11pter to 11p15.1 in mosaic	focal form of hyperinsulinism restricted to pancreas (gene ABCC8 in 11p15.1)	{1236}
11- WpU-seg/ pter/ mos/ 6-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14.3 mosaic 96%	BWS	{782} case 11
11- WpU-seg/ pter/ mos/ 7-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14.2 mosaic 65%	BWS	{782} case 6
11- WpU-seg/ pter/ mos/ 8-1	n.a.	postnatal	PBL	46 --- 11pter to 11p14 somatic mosaicism	BWS, Wilmstumor	{208} 1 case
11- WpU-seg/ pter/ mos/ 8-2 to 8-10	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14 all cases also somatic mosaicism	BWS	{330} 9 cases
11- WpU-seg/ pter/ mos/ 8-11	n.a.	postnatal	PBL	n.a. --- 11pter to 11p14 mosaic 20-50%	BWS	{955} case 2
11- WpU-seg/ pter/ mos/ 9-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p13 mosaic 21%	BWS	{782} case 9
11- WpU-seg/ pter/ mos/ 10-1 to 10-5	n.a.	postnatal	PBL	n.a. --- 11pter to 11p12 mosaic cases	BWS	{955} cases 3-5; 18-19
11- WpU-seg/ pter/ mos/ 11-1 to 11-2	n.a.	newborn	PBL	n.a. --- 11pter to 11p11 in mosaic	BWS	{513} 2 cases
11- WpU-seg/ pter/ mos/ 12-1	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11.2 mosaic 12%	BWS	{782} case 5
11- WpU- seg-pter/ mos/ 12-2	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11.2 mosaic 18%	BWS	{782} case 10
11- WpU-seg/ pter/ mos/ 12-3	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11.2 mosaic 58%	BWS	{782} case 13
11- WpU-seg/ pter/ mos/ 12-4	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11.2 mosaic 85%	BWS	{782} case 15
11- WpU-seg/ pter/ mos/ 12-5	male	newborn	PBL	n.a. --- 11pter to 11p11.2 mosaic 10-15%	BWS	{818} case 2
11- WpU-seg/ pter/ mos/ 13-1 to 13-5	n.a.	postnatal	PBL	n.a. --- 11pter to 11p11.1~11.2 mosaic	BWS	{955} cases 6-9, 24
11- WpU-seg-/ pter/ mos/ 14-1	male	newborn	PBL	n.a. --- 11pter to 11p11.1 mosaic 7-8%	BWS	{818} case 1
11- WpU-seg/ p15.5/ mos/ 1-1	n.a.	newborn	PBL	n.a. --- 11p15.5 to 11p14~13 in mosaic	BWS	{507}
11- WpU-seg/ p14.2/ mos/ 1-1	male	14y	PBL	n.a. --- 11p14.2-11p13 in mosaic	Sickle cell anemia (gene HBB in 11p15.4)	{563}

pat UPD-cases with or unclear clinical correlation + other imbalances

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-imb/ 1-1	male	prenatal	AF, placenta	AF: 47,XY,+11/46,XY placenta: 47,XY,+11	IUGR, TOP	{374}
11- WpU-imb/ 1-2	n.a.	prenatal	PBL	46,XN,+11 acc. to NIPT	TOP	{1389} case 121
11- WpU-imb/ 2-1	male	newborn	PBL	46,XY,der(11)(pter→q13.4:: q13.4→q14.3: :q14.3→q13.4: :q13.4→qter) UPD(11)seg 11q14.3 to 11qter	DD, growth retardation; DYS	{900}
11- WpU-imb/ 3-1	n.a.	prenatal	AF	46,XN,+3,+7,+8	hydatiform mole	{958}
11- WpU-imb/ 4-1	male	newborn	PBL	46,XY,trp(11)(q13.4q14.3) UPD only in triplicated region	dwarphism, DD, DYS	{1301}

mosaic cases

case no.	gender	age at diagnosis	studied material	GTG-banding result	clinical symptoms	reference
11- WpU-imb/ mos/ 1-1	-	-	-	-	-	-