clinical symptoms

In general 70% of sSMC carriers are clinically normal. The figures listed above
are based on the bias, that mainly clinically aberrant cases are studied and reported in literature!

UPD (uniparental disomy) cases:

UPD(4)mat

UPD(4)pat

UPD(4)mat or pat

the probably non-dosage sensitive pericentric region of chromosome 4
schematic cytogenetic depiction	short (= p-) arm het long (= q-) arm p15 p14 p13 cen q12 q13 q21 no clinical signs clinical signs
schematic molecular- cytogenetic depiction	Data is converted between genome versions by UCSC browser! Note the changes defined there for centromere-sizes; due to that and due to 'new insertions and deletions', positions are not always seeming logical comparing different versions listed  genomic version critical region p-arm uncritical region p-arm centromere uncritical region q-arm critical region q-arm NCBI 36/ hg18 39.80 44.03 48.70 - 52.40 63.50 unknown GRCh 37/ hg19 40.12 44.33 48.20 - 52.70 63.82 unknown GRCh 38/ hg38 40.12 44.33 48.20 - 51.80 62.95 unknown   Positions given in megabasepair (Mbp) acc. to cases marked as ***