ChromosOmics - Database
tl_files/tiny_templates/Bilder
                        TL/hetmorh-book.jpg

                                                     - CHROMOSOME  10  -                                                   


Heterochromatic

- centromeric
- other heterochromatic variants
Euchromatic

- euchromatic deletions
- euchromatic duplications
References


Heterochromatic - (peri)centromeric variants

case no.
(molecular) cytogenetic result
clinical symptoms
reference
10-
cen+/

1-1 to few
10cen+
D10Z1

none
{1 pages 68-69}
10-
cen-/
1-1 to few

10cen-
D10Z1

none
{1 pages 68-69}
10-
inv/
1-1 to few

inv(10)(p11.2q21.2)
none
{1 pages 68-69}

Heterochromatic - other heterochromatic variants

case no.
(molecular) cytogenetic result
clinical symptoms
reference
10-
HHM-
acro/

1-1
der(10)t(10;acro)(q26.3;p11.2)
none
{1; 26}

Euchromatic deletions

case no.
(molecular) cytogenetic result
clinical symptoms
reference
10-
EHM-del
q11.2q11.23/

1-1
del(10)(q11.2q11.23)
none
{1}
10-
EHM-del
q11.2q21.2/
1-1

del(10)(q11.2q21.2)
none
{1}
10-
EHM-del
q22.3q23.31/
1-1

del(10)(q22.3q23.31)
mild to moderate
{1}
10-
EHM-del
q26.13qter/
1-1 to 1-2

del(10)(q26.13)
none
mild to moderate

{1; 68; 77}
10-
EHM-del
q26.13qter/
2-1 to few

del(10)(q26.13)
reduction of signal size

none
{77}

Euchromatic duplications

case no.
(molecular) cytogenetic result
clinical symptoms
reference
10-
EHM-dup
p15p14/
1-1

dup(10)(p15p14)
mild to moderate
{1}
10-
EHM-dup
p15p13/
1-1

dup(10)(p15p13)
mild to moderate
{1}
10-
EHM-dup
p14p13/
1-1

dup(10)(p14p13)
none
{1}
10-
EHM-dup
p11.23p11.21/
1-1

dup(10)(p11.23p11.21)
aCGH: 30.345109-42.826062 Mb

none
{112}
10-
EHM-dup
p11.22q11.22/
1-1 to few

sSMC(10)
none
{sSMC
page}

10-
EHM-dup
q26.3qter/
1-1

dup(10)(q26.3qter)
none in father of affectced child
{68}