Thomas Liehr (2019)
web-presence: https://cs-tl.de/Start.html
Created by Dr. Thomas Liehr (PhD),
affiliation: Institute of Human Genetics, 07740 Jena, Germany;
e-mail: Thomas.Liehr@med.uni-jena.de or LiehrT@web.de
Book Chapters
| 2024 | ||
| 120 |
 |
T Liehr. Challenges and ethical issues surrounding noninvasive prenatal screening (NIPS). In: Non-invasive prenatal screening (NIPS) in clinical practice. RA Rather, SC Saha (eds.) Springer pp 241-257. 2024 ISBN 978-9819764013 |
| 119 |
A Weise, T
Liehr. Advanced genomic approaches in noninvasive prenatal screening: The road from conventional karyotyping to next-generation sequencing. In: see above pp 97-104. |
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| 118 |
 |
T Liehr. FISH-Banding for Characterization of Simple and Complex Chromosomal Rearrangements in Cancer. In: JC Ye, H Heng (eds.) Cancer Cytogenetics and Cytogenomics Springer pp 205-211. 2024 ISBN 978-1071639450 |
| 117 |
 |
T Liehr, C
Andersen, S Wynn, A
Pelling.
Ring chromosomes from patients’ perspective. In: P Li, T Liehr (ed.) Human ring chromosomes. A practical guide for clinicians and families. Springer pp 363-401. 2024 ISBN 978-3031475290 |
| 116 |
T Liehr. Small supernumerary ring chromosomes. In: see above pp 353-362. |
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| 115 |
T Liehr. Ring chromosome 7. In: see above pp 139-150. |
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| 114 |
Genetic databases and online ring chromosome registry. In: see above pp 31-42. |
|
113 |
Historical perspective of human ring chromosomes. In: see above pp 3-16. |
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| 2023 | ||
112 |
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FISH—and CRISPR/CAS9. In: T Liehr (Ed.) Cytogenetics and Molecular Cytogenetics. 1st Edition Taylor and Francis pp 353-356. |
111 |
FISH—On fibers pp 207-210 |
|
110 |
FISH—in three dimensions—3D-FISH pp 201-206 |
|
109 |
FISH—Detection of individual radio sensitivity pp 163-170 |
|
108 |
FISH—Centromere- and heterochromatin-specific multicolor probe sets pp 157-162 |
|
107 |
Multicolor-FISH—Methods and applications pp 151-156 |
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106 |
pp 121-150 |
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105 |
FISH—in spontaneously aborted products of conceptions. pp 117-120 |
|
104 |
pp 111-116 |
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103 |
FISH—in tissues. pp 105-110 |
|
102 |
FISH—An overview. pp 35-42 |
|
101 |
pp 1-6 |
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| 2022 | ||
100 |
 |
A
Weise, T
Liehr Cytogenetics. In: Reference
Collection in Life Science.
Elsevier,ISBN 9780128096338, https://doi.org/10.1016/B978-0-12-822563-9.00054-8. 2022 |
99 |
|
Predictive genetic testing in early human reproduction. In: Predictive Medicine Evolution. Ed. V.S. Baranov Eco Vector St. Petersburg pp 286-296 2022 ISBN 9785907201675 |
98 |
 |
Measuring telomere length: A timeline review on the state-of art techniques. In: N Rezaei (ed.) Encyclopedia of Infection and Immunity (4) pp 259-275 2022 ISBN 9780128187319 |
| 2021 | ||
97 |
|
ПРОГНОСТИЧЕСКОЕ ГЕНЕТИЧЕСКОЕ ТЕСТИРОВАНИЕ НА РАННИХ СТАДИЯХ РЕПРОДУКЦИИ (Predictive genetic tests in early stades of reproduction). In: V.S. Baranvov. ЭВОЛЮЦИЯ ПРЕДИКТИВНОЙ МЕДИЦИНЫ (Evolution of Predictive Medicine). ZKO-VECTOR St. Petersburg 2021 |
96 |
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T Liehr Repetitive elements, heteromorphisms and copy number variants. In: T Liehr. Cytogenomics. pp 373-388 Academic Press 2021 ISBN: 9780128235799 |
95 |
Interchromosomal interactions with meaning for disease. pp 349-356 |
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94 |
Nuclear architecture. pp 297-305 |
|
93 |
Molecular karyotyping. pp 72-85 |
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92 |
Molecular cytogenetics. pp 35-45 |
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91 |
Cytogenetics. pp 25-34 |
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90 |
pp 11-24 |
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89 |
A Definition for Cytogenomics – also may be called Chromosomics. pp 1-7 |
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| 2020 | ||
88 |
 |
T
Liehr Chromosome architecture studied by high-resolution FISH banding in three-dimensionally preserved human interphase nuclei. In: Human Interphase Chromosomes Biomedical Aspects. Eds: I Iourov, S Vorsanova, Y Yurov pp 147-155 Springer 2020 ISBN 9781461465577 |
| 2019 | ||
87 |
 |
A
Weise, T Liehr Rapid Prenatal Aneuploidy Screening by Fluorescence In Situ Hybridization (FISH). In: Methods Mol Biol. Series on Prenatal Diagnosis 1885:129-137 Springer 2019 ISBN: 978-1493988877 |
| 2018 | ||
86 |
 |
T Liehr, M Ziegler, S Löhmer, A Weise Assessing skewed X-chromosome inactivation. In: Current protocols of Human Genetics 98: e66 Wiley 2018 |
85 |
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Leihmutterschaft und Genetik. In: Leihmutterschaft und Familie; Impulse aus Recht, Theologie und Medizin. Ed: E Schramm, M Wermke. pp 183-190 Springer 2018 ISBN 978-3662562512 |
| 84 |  |
T
Liehr Chromothripsis detectable in small supernumerary marker chromosomes (sSMC) using fluorescence in situ hybridization (FISH). In: Chromothripsis; series Methods in Molecular Biology pp 79-84 Springer 2018 ISBN: 978-1493977796 |
83 |
 |
a T Liehr Characterization of RB1 deletions in interphase and metaphase by molecular cytogenetics exemplified in chronic lymphatic leukemia. In: The Retinoblastoma Protein; series Methods in Molecular Biology pp 1-6 Springer 2018 ISBN: 978-1493975655 |
| 2017 | ||
82 |
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A Weise, T Liehr Background. In: Fluorescence in situ Hybridization (FISH) – Application Guide, 2nd Ed. Springer pp 1-14 Ed.: T Liehr 2017 ISBN: 978-3662529577 |
| 81 | T Liehr Classification of FISH probes. In: see above pp 43-47 |
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| 80 | T Liehr Commercial FISH probes. In: see above pp 49-61 |
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| 79 | N Kosyakova, T Liehr,
AB Hamid Al-Rikabi FISH-microdissection. In: see above pp 81-99 |
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| 78 | T Liehr Homemade locus-specific FISH probes: bacterial artificial chromosomes. In: see above pp 101-106 |
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| 77 | T Liehr, K
Kreskowski, M Ziegler, K Piaszinski, K Rittscher The standard FISH procedure. In: see above pp 109-118 |
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| 76 | A Weise, T Liehr Microwave treatment for better FISH results in a shorter time. In: see above pp 119-122 |
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| 75 | G Joksic, I Joksic, J
Filipović, T Liehr Telomere length measurement by FISH. In: see above pp 147-152 |
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| 74 | A Weise, T Liehr Pre- and postnatal diagnostics and research on peripheral blood, bone marrow chorion, amniocytes, and fibroblasts. In: see above pp 171-180 |
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| 73 | T Liehr, M
Ziegler Application of FISH to previously GTG-banded and/or embedded cytogenetic slides. In: see above pp 181-184 |
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| 72 | A Weise, M Ziegler, T
Liehr FISH in uncultivated amniocytes. In: see above pp 185-188 |
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| 71 | E Alhourani, MAK Othman, SS
Hussein Azawi, T Liehr Tumorcytogenetic diagnostics and research on blood and bone marrow smears or effusions. In: see above pp 189-194 |
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| 70 | T Liehr, N
Kosyakova Characterization of mosaicism in different easy-to-acquire body tissues such as buccal smears, skin abrasions, hair root cells or urine. In: see above pp 195-200 |
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| 69 | T Liehr Characterization of archived formalin-fixed/paraffin-embedded or cryofixed tissue, including nucleus extraction. In: see above pp 201-208 |
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| 68 | T Liehr Two- to three-color FISH. In: see above pp 227-232 |
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| 67 | T Liehr, N
Kosyakova Multiplex FISH and spectral karyotyping. In: see above pp 233-239 |
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| 66 | T Liehr FISH banding techniques. In: see above pp 241-247 |
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| 65 | T Liehr, A Weise,
N Kosyakova. cenM-FISH approaches. In: see above pp 249-255 |
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| 64 | T Liehr, N
Kosyakova, A Weise, AB Hamid Al-Rikabi Heterochromatin directed M-FISH (HCM-FISH). In: see above pp 257-259 |
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| 63 | A Weise, T Liehr Subtelomeric and/or subcentromeric probe sets. In: see above pp 261-269 |
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| 62 | T Liehr Bar-coding is back. In: see above pp 271-274 |
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| 61 | A Weise, T Liehr Parental origin determination FISH: pod-FISH. In: see above pp 295-300 |
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| 60 | E Klein, T Liehr CENP-antibodies used additionally to FISH. In: see above pp 347-351 |
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| 59 | T Liehr, S Hauke Interphase FISH in diagnostics. In: see above pp 355-359 |
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| 58 | G Hovhannisyan, T Harutyunyan,
T Liehr Micronucleus FISH. In: see above pp 379-383 |
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| 57 | T Liehr, N
Kosyakova Three-dimensional interphase analysis enabled by suspension FISH. In: see above pp 385-392 |
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| 56 | T Liehr FISH on insect cells transfected with heterologous DNA. In: see above pp 473-476 |
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| 55 | T Liehr Comparative genomic hybridization (CGH) and microdissection-based CGH (micro-CGH). In: see above pp 561-565 |
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54 |
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T Liehr, MAK Othman, K Rittscher Multi-color karyotyping and FISH-banding (MCB/mBAND). In: Cancer Cytogenetics: Methods and Protocols pp 181-187 Springer 2017 ISBN: 978-1493982783 |
| 2015 | ||
53 |
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F Santiago, T Liehr Genetics monitoring of gas stations workers. In: The health and environmental threats related to gas stations. GA Brown (Ed.) pp 69-77 Lambert Academic Publishing 2015 ISBN: 978-3659814457 |
52 |
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IE Gomaa, S Bhatt, T
Liehr, M Bakr, TA El-Tayeb A study on biological applicaton of CO/Ag nanoparticles cytotoxicity and genotoxicity. In: Nanomaterials and Nanotechnology for Composites Design, Simulation and Applications. Eds: A. K. Haghi, S Thomas, A Pourhashemi, A Hamrang, E Klodzinska pp 139–153 Apple Academic Press 2015 ISBN: 978-1-77188-065-7 |
51 |
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IE Gomaa, S Bhatt, T
Liehr, M Bakr, TA El-Tayeb AG and CO/AG nanoparticles cytotoxicity and genotoxicity study on HEP-2 and blood lymphocyte cells. In: Chemical Technology, Key Developments in Applied Chemistry, Biochemistry and Materials Science Eds: N Guarrotxena, GE Zaikov, AK Haghi pp 13-30 Apple Academic Press 2015 ISBN: 978-1-77188-051-0 |
50 |
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A Weise, MA Othman, S Bhatt, S Löhmer, T Liehr 2015 Application of BAC-Probes to visualize copy number variants (CNVs). Ed. K Narayanan In: Bacterial Artificial Chromosomes, 2. Ed. Methods Mol Biol 1227:299-307 Springer 2015 ISBN: 978-1493954308 |
| 49 | K
Mrasek, K Wilhelm, LG Quintana, L Theuss, T
Liehr, A Leskovac, J
Filipovic, G Joksic, I Joksic, A Weise. BAC-probes applied for characterization of fragile sites (FS). In: see above 289-298 |
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| 48 | AB
Hamid, X Fan, N Kosyakova, G Radhakrishnan, T
Liehr, T Karamysheva New BAC probe set to narrow down chromosomal breakpoints in small and large derivative chromosomes, especially suited for mosaic conditions. In: see above 279-287 |
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| 2014 | ||
47 |
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T Liehr Fluorescence in situ Hybridization (FISH): When and how to do? How to interpret? How to counsel? In: Genetics in Clinical Practice: Symptoms, Diagnosis and Therapy. Eds.: J. Sheth and F. Sheth. pp 73-92 Jaypee Brothers Medical Publishers 2014 ISBN 978-9351521532. |
| 2013 | ||
46 |
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IY Iourov, T Liehr, SG Vorsanova, YB Yurov Interphase chromosome-specific multicolor banding. In: Human Interphase Chromosomes - Biomedical Aspects. Ed: YB Yurov, SG Vorsanova, IY Iourov pp 161-169 Springer 2013 ISBN: 978-1489985392 |
| 45 | T Liehr,
H Mkrtchyan, M Manvelyan, T Karamysheva, E Klein,
S Bhatt Chromosome architecture studied by high-resolution FISH-banding in three dimensionally preserved human interphase nuclei. In: see above pp 171-178 |
|
| 2010 | ||
44 |
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T Liehr, A Weise, S Hinreiner, H Mkrtchyan, K Mrasek, N Kosyakova Characterization of chromosomal rearrangements using multicolor-banding (MCB/m-band). In Fluorescence in situ Hybridization (FISH): Protocols and Applications (Methods in Molecular Biology) Ed JM Bridger and EV Volpi 659:231-238 Springer 2010 ISBN: 978-1607617884 |
| 43 | A
Weise, M Gross, S Hinreiner, V Witthuhn, H
Mkrtchyan, T Liehr POD-FISH, a new technique for parental origin determination based on copy number variation polymorphism. In: see above 659:291-298 |
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42 |
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T Liehr Fluorescence in situ hybridization (FISH) - quality issues in molecular cytogenetics. In: Quality Issues in Clinical Genetic Services. U Kristoffersson, J Schmidtke, JJ Cassiman (Eds.), pp 315-320 Springer 2010 ISBN 9-78-90-481-3918-7 |
| 2009 | ||
41 |
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T Liehr F Pellestor Molecular cytogenetics: The standard FISH and PRINS procedure. In: Fluorescence in situ Hybridization (FISH) – Application Guide, 2nd Ed. pp 23-34 Springer, Berlin 2009 ISBN: 978-3540705802 |
| 40 |
A Weise, K Mrasek, N
Kosyakova, H Mkrtchyan, M Gross, V Klaschka, T
Liehr. ISH probes derived from BACs, including microwave treatment for better FISH-results. In: see above pp 53-60 |
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| 39 |
A Weise, T Liehr Pre- and postnatal diagnostics and research on peripheral blood, chorion, amniocytes, and fibroblasts. In: see above pp 113-122 |
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| 38 |
A Heller, M Gross, V Witthuhn,
K Behr, S Hinreiner, H Mkrtchyan, T Liehr Tumorcytogenetic diagnostics and research on uncultured blood or bone marrow and smears. In: see above pp 131-136 |
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| 37 |
T Liehr, E
Gebhart Application of FISH on archival cytogenetic slides. In: see above pp 137-140 |
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| 36 |
K Mrasek, A Weise, M Gross, H
Mkrtchyan, T Liehr Characterization of mosaicism in various easy-to acquire body tissues such as buccal smears, hair root cells or urine. In: see above pp 141-146 |
|
| 35 |
T Liehr, M
Manvelyan Characterization of archived formalin-fixed/paraffin-embedded or cryofixed tissue, including nucleus extraction. In: see above pp 147-156 |
|
| 34 |
T Liehr, K
Mrasek, N Kosyakova, H Mkrtchyan, J Melo, A
Polityko, L Brecevic Multiplex FISH and spectral karyotyping. In: see above pp 175-182 |
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| 33 |
T Liehr, K
Mrasek, N Kosyakova, H Nelle, V Trifonov, M
Manvelyan, A Weise FISH-banding techniques. In: see above pp 243-250 |
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| 32 | N Kosyakova, A Weise, K Mrasek,
H Mkrtchyan, V Klaschka, E Ewers, D Reich, N
Rüdiger, T Liehr cenM-FISH approaches. In: see above pp 251-260 |
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| 31 |
A Weise, K Mrasek, M Gross, V
Klaschka, T Liehr Subtelomeric and/or subcentromeric probe sets. In: see above pp 261-168 |
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| 30 |
A Weise, K Mrasek, H Mkrtchyan,
M Gross, S Hinreiner, T Liehr Parental origin determination FISH: pod-FISH. In: see above pp 293-300 |
|
| 29 | F Hunstig, M Manvelyan, S
Bhatt, U Steinhaeuser, T Liehr Three-dimensional interphase analysis enabled by suspension FISH. In: see above pp 313-322 |
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| 28 | T Liehr FISH on insect cells transfected with heterologous DNA: a single-cell-directed approach. In: see above pp 361-364 |
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| 27 | A Heller, T Liehr Micro CGH: Microdissection-based comparative genomic hybridization. In: see above pp 411-420 |
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| 26 | T Liehr, A Weise FISH and chips on the internet. In: see above pp 441-44 |
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| 2008 | ||
25 |
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T Liehr Characterization of prenatally assessed de novo small supernumerary marker chromosomes (sSMC) by molecular cytogenetics. In: Methods Mol Biol. series on Prenatal Diagnosis; Vol 444 pp 27-38 Humana Press 2008 ISBN: 978-1-58829-803-4 |
| 24 | A
Weise, T Liehr Rapid Prenatal Aneuploidy Screening by Fluorescence In Situ Hybridization (FISH). In: see above pp 39-48 |
|
| 2007 | ||
23 |
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A Weise, T Liehr Untersuchungen zur Karyotypevolution der großen Menschenaffen. In: Beiträge zur Archäozoologie und prähistorischen Anthropologie, Band VI. Ed: N. Benecke pp 232-236 2007 ISBN 978-3-937517-81-0 |
| 2006 | ||
22 |
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T Liehr Application of YACs in fluorescence in situ hybridization (FISH). In: Methods in Molecular Biology YAC protocols,m 2. ed Ed A MacKenzie, pp 175-186 Humana Pres 2006 ISBN 1-588296121 |
| 2004 | ||
21
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T Liehr FISH-Banding Methods and their Clinical Applications. In: Encyclopedia of Diagnostic Genomics and Proteomics Eds: J Fuchs; M Podda pp 457-460 Taylor & Francis Inc 2004 ISBN: 0824747941 and 0824755642 |
20 |
T Liehr FISH - Centromere specific multicolor FISH (CenM-FISH) – a versatile tool for characterization of small supernumerary marker chromosomes. In: see above pp 468-470 |
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| 19 | A Kuechler, T
Liehr FISH - Detection of individual radiosensitivity. In: see above pp 474-477 |
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| 2002 | ||
18 |
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T Liehr,
A Nietzel, M Rocchi, A Heller, H Starke, U
Claussen, F v Eggeling Centromere-specific multicolor-FISH (cenM-FISH) followed by analysis for uniparental disomy - a useful tool in prenatal diagnosis. In: Early prenatal diagnosis, fetal cells and DNA in the mother - present state and perpectives. Eds: M Macek, DW Bianchi, H Chuckle pp 293-300 The Karolinum Press 2002 ISBN: 80-24603977 |
17 |
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T Liehr, B Rautenstrauss FISH analysis of interphase nuclei extracted from paraffin-embedded tissue. In: The Ultimate FISHing Guide -sample preparation and application protocols. European Edition pp 15-16 Q-Biogene 2002 ISBN: n.a. |
16 |
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T Liehr, U Claussen FISH on chromosome preparations of peripheral blood. In: T Liehr, B Rautenstrauss FISH-Technology, Springer-labmanual pp 73-81 Springer, Berlin 2002 ISBN: 3-54067276118. |
| 15 | T Liehr FISH on uncultured blood or bone marrow. In: see above pp 82-89 |
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| 14 | T Liehr FISH on blood or bone marrow smears. In: see above pp 90-96 |
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| 13 | T Liehr FISH on hair root cells. In: see above pp 109-114 |
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| 12 | T Liehr Nucleus extraction from formalinfixed/paraffin embedded tissue. In: see above pp 162-170 |
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| 11 | B Rautenstrauss, T Liehr Nucleus extraction from cryofixed tissue. In: see above pp 176-184 |
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| 10 | T Liehr FISH on insect cells transfected with heterologous DNA. In: see above pp 323-328 |
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| 9 | A Nietzel, A Heller, H Starke,
T Liehr Centromere-specific multicolor-FISH (cenM-FISH). In: see above pp 425-431 |
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| 8 | T Liehr Internet sites related to cytogenetics and molecular cytogenetics. In: see above pp 485-486 |
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| 2000 | ||
7 |
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T Liehr Cytogenetics of ovarian cancer: Technical overview. In: Methods in Molecular Medicine: Ovarian Cancer – Methods and Protocols, Ed.: J.M.S. Bartlett pp 207-213 Humana Press 2000 ISBN: 0-896035832 |
| 6 | T
Liehr Interphase cytogenetics in frozen ovarian tumor tissue. In: see above pp 215-221 |
|
5 |
S Neubauer, T Liehr Interphase cytogenetics in paraffin embedded ovarian tissue. In: see above pp 223-228 |
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| 1997 | ||
4 |
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S Neubauer, S Birkenhake, I Schneider, T Liehr, E Gebhart, R Fietkau, R Sauer DNA-Reparatur an Tumor- und Normalgewebe - Erste Ergebnisse der Bestimmung mit Hilfe des Comet-Assays. In: Experimentelle Strahlentherapie und klinische Strahlenbiologie, Band 6 pp 175-179 Ed.: Beck-Bornholdt H-P, Baumann M 1997 ISBN: n.a. |
| 1996 | ||
3 |
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KD Bathke, T Liehr, AB Ekici, H Grehl, D Heuss, B Rautenstrauss, B Neundörfer Das klinische Bild einer hereditären motosensorischen Neuropathie Typ I (CMT1) bei Patienten mit einer HNPP-Deletion auf Chromosom 17p11.2 und einer PMP22-Punktmutation. In: Jahrbuch der neuromuskulären Erkrankungen Acris 1996 ISBN: 3-89075-112-1 |
2 |
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T Liehr, B Rautenstrauss FISH analysis of interphase nuclei extracted from paraffin-embedded tissue. In: The Ultimate FISHing Guide - sample preparation and application protocols. pp E4-E6 ONCOR 1996 ISBN n.a. |
| 1994 | ||
1 |
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H Grehl, B Rautenstrauss, T Liehr, A Ekici, H Finder, K D Bathke, B Neundörfer Nachweis der chromosomalen 17p11.2 Duplikation bei HMSN 1A (Hereditäre motorische sensible Neuropathie) und der korrespondierenden Deletion bei HNPP (tomakolöse Neuropathie) durch Southern-Hybridisierung und Fluoreszenz-in-situ-Hybridisierung. In: Verhandlungen der deutschen Gesellschaft für Neurologie Bd. 8 pp 441-443 Springer 1994 ISBN n.a. |
