ChromosOmics - Database

Icon by Leon Liehr                   

                                                  EKF-CELL-BANK -                                                 
START

Between 2010 and 2013 the Else Kröner-Fresenius foundation sponsored the establishment of a cellbank for sSMC
(applicants: Dr. Thomas Liehr, Jena and Dr. Marianne Volleth, Magdeburg, Germany).


All up to now established and in Jena collected cell lines are included on this page (see below).

For research purposes these cell lines are available on reqeust for free (Thomas.Liehr@med.uni-jena.de).
We only ask for the covering the costs the thawing, cell culture and mailing of the lines.
At least citation of this cell bank and acknowledgment for providing the cell lines is expected in any published paper using any of these lines.

In ref {188} the following cell lines were used under following designations: 13L0092 = EKF-Y-q11.21/1-i as A3; 14L0224 = EKF-#22-q11.1/3-m as M1;


sSMC- cell line
BY CHROMOSOME
sSMC
1
sSMC
2
sSMC
3
sSMC
4
sSMC
5
sSMC
(1)/5/19
sSMC
6
sSMC
7
sSMC
8
sSMC
9
sSMC
10
sSMC
11
sSMC
12
sSMC
13
sSMC
13/21
sSMC
14
sSMC
14/22

sSMC
16
sSMC
17
sSMC
18
sSMC
19
sSMC
20
sSMC
21
sSMC
22
sSMC
X
sSMC
Y



sSMC
acro
sSMC
non-acro
sSMC
multiple



DISCLAIMER


The nomenclature for cell lines is complex and explained here
Else Kröner-Fresenius cellbank


EKF-cell line
case no.

GTG-banding result/
grade of mosaicism
final result for the sSMC
clinical symptoms/
reference

cell line of parents
identifier
(internal use)

EKF-
#1-p13.2/
1-r
in cell line:
47,XY,+mar[0]/
46,XY[50]
r(1)(::p13.2→q12::)
(115.2MB-cen) [hg19]
see 01-O-p13.2/2-1 EKF-#1-p13.2/
1-r-
mother
EKF-#1-p13.2/
1-r
-father
14L0150
14L0146
14L0148
EKF-
#1-p11.1/
1-r
in cell line:
47,XY,+r[3]/
46,XY[47]
interphase: 16 of 200 cells
r(1)(::p11.1q22::)
array-CGH: 105.98-188.41MB
r(1)(::p21.1
q31.1::)
see 01-W-p11.1/3-1 n.a. 05P0749
EKF-
#1-p11.1/
1-m
in cell line:
47,XY,+mar[25]/

46,XY[25]
min(1)(:p11.1q11:) see 01-CW-5 EKF-#1-p11.1/1-m-mother
EKF-#1-p11.1/1-m-father
EKF-#1-p11.1/1-m-brother
12L0128
13L0176
13L0267
13L0268
EKF-
#1-p11.1/
2-m
in cell line:
47,XX,+mar[31]/
46,XX[21]
min(1)(:p11.1q12:) see 01-O-p11.1/3-1 n.a. 12L0231
EKF-
#1-p11.1/
3-m
in cell line:
47,XX,+mar[59]/
46,XX[41]
min(1)(:p11.1q12:) see 01-O-p11.1/3-6 n.a. 12L0084
EKF-
#1/5/19/
1-m
in cell line:
47,XX,+mar[70%]/
46,XX[30%]
min(1)(:p11q11:) or min(5)(:p11q11.1:) or min(19)(:p11q11)
see 05/19-W-2 n.a. GGB02438F, 2197 provided by Teleton foundation, Italy
EKF-
#2-N/
1-r
in cell line:
47,XX,del(2)(q22q32.2),

+r(2)(q22q32.2)[0]/
46,XX,del(2)(q22q32.2)[50]
r(2)(q22q32.2) see McCl-02-N-q35/1-1 EKF-#2-N/1-r-mother;
EKF-#2-N/1-r-father
05PO417
05PO418
05PO419
EKF-
#2-p11.2/
1-m
in cell line:
47,XY,+mar[1]/
46,XY[60]
interphase: 3 of 200 cells
min(2)(:p11.2q11.1:)
FISH-data: RP11-303I4 (80.7MB); RP11-316G9 (89.7MB); RP11-271A22 = AC128677.4 (91.5MB) on sSMC
see 02-W-p11.2/1-2 n.a. 2010B113
EKF-
#2-p11.2/
2-m
in cell line:
48,XY,+mar1,+mar2[1]/
47,XY,+mar[1]/
46,XY[64]
mar1: min(2)(:p11.2→q11.2:),
mar2: min(2)(:p11.1→q11.2:)
see 02-O-p11.2/2-2 n.a. 14L0264
EKF-
#2-p11.2/
2-m/r
in cell line:
47,XY,+mar[6]/
46,XY[44]
interphase: 22 of 189 cells
r(2)(::p11.1q12.1::)
91.01-101.58 MB
array: r(2)(::p11.2
q12.1::)
see 02-O-p11.2/1-1 n.a. 06P0793
EKF-
#2-p11.1/
1-m
in cell line:
47,XX,+mar[2]/
46,XX[98]
min(2)(:p11.1→q11.2:)
FISH-data: RP11-708D7: 95.0 MB
aCGH: 91.27-99.97
see 02-O-p11.1/5-1 EKF-#2-p11.1/1-m-father 12L0052
13L0077
EKF-
#2-p11.1/
2-m
in cell line:
47,XX,+mar[20]/
46,XX[80]
min or r(2)(:p11.1→q11.2:)
FISH-data: RP11-708D7: 95.0 MB
see 02-O-p11.1/5-2 EKF-#2-p11.1/2-m-mother
EKF-#2-p11.1/2-m-father
12L0107
13L0259
13L0260
EKF-
#3-p12.1/
1-m/r
in cell line:
47,XX,+mar[39]/

46,XX[57]
interphase: 127 of 500 cells
r(3)(::p12.1q11.1::)[14]/ min(3)(:p12.1q11.1:)[5]/ min(3)(:p12.1q11.1:
:q11.1
p12.1:)[2]
FISH-data: RP11-91A15 (89.6 MB) on sSMC
see 03-O-p12.1/2-2 n.a. 07PO736
EKF-
#4-p11/
1-m
in cell line:
47,XY,+mar[3]/

46,XY[56]
min(4)(:p11q12:)[9]/
min(4)(:q12
p11::p11q12:)[1]
see 04-W-p11/2-1 n.a. 12L0247
EKF-
#4-p11/
2-m
in cell line:
48,XY,+marx2[1]/
47,XY,+mar[11]/

46,XY[25]
min(4)(:p11q12:) see 04-O-p11.1/1-1 n.a. 13L0227
EKF-
#5-p13.2/
1-m
in cell line:
47,XY,+mar[1]/
46,XY[99]
min(5)(::p13.2q11.1::)
FISH-data: break in p-arm between: 37.00-37.18 MB
see 05-W-p13.2/2-1 n.a. 12L0054
EKF-
#5-p13.2/
1-r
in cell line:
47,XY,+mar[16]/

46,XY[63]
r(5)(::p13.2q11.1::)[9]/
r(5;5)(::p13.2
q11.1:
:p13.2
q11.1::)[1]
see 05-W-p13.2/1-1 n.a. 12L0135
EKF-
#5-p13.1/
1-mar
in cell line:
47,XY,+mar[1]/
46,XY[44]
mar(5)(:p13.1q11.2:) see 05-W-p13.1/2-1 n.a.  GGB03237M, 2318 provided by Teleton foundation, Italy
EKF-
#5-p12/
1-m
in cell line:
47,XX,+mar[54]/

46,XX[46]
min(5)(:p12q11.1:)
FISH-data:
RP11-19F12 (41.24MB) on sSMC
see 05-O-p12/1-1 n.a. 12L0077
EKF-
#6-p11.1/
1-m
in cell line:
48,XY,+marx2[0]/

47,XY,+mar[25]
46,XY[125]
min(6)(:p11.1q12:) see 06-W-p11.1/1-1 n.a. 05P0223
EKF-
#6-p11.1/
2-i
in cell line:
47,XY,+mar[1]/
46,XY[129]
interphase: 21 of 180 cells
dic(6;6)(:p11q11::p11q11:) see 06-O-p11.1/2-1 n.a. 11L013
EKF-
#7-p12/
1-m
in cell line:
47,XY,+mar[0]/
46,XY[50]
min(7)(:p12p11.1:)
maternal (iso-)disomy UPD 7
aCGH: 44,864,487 Mb-57,562,142 MB
see 07-U-13 n.a. 12L0211
EKF-
#7-p11.2/
1-m
in cell line:
47,XX,+r[53]/
46,XX[47]
min(7)(:p11.2q11.1:)
FISH-data: RP11-10F11 (56.45 MB) on sSMC
aCGH: 45.07-64.85
CR-FISH: break in p between 55.47 and 56,46
maternal (iso-)disomy UPD 7

seq[GRCh37] +der(7)(:q11.21q11.21::p11.2->q11.21:)
chr7:g.[63674966~_63681708:
:ATTTGTAAAAAAACTTT:
:62394403_63674966inv:
:57645143_cen_62050000]add
see 07-U-14 EKF-#7-p11.2/1-m-father 12L0080
13L0113
EKF-
#7-p11.2/
2-m
in cell line:
47,XX,+mar[25]/
46,XX[22]
in cell line (mother):
4
7,XX,+mar[25]/
46,XX[20]
min(7)(:p11.2q11.1:)
FISH-data: RP11-10F11 (56.45 MB)
see 07-O-p11.2/2-1 EKF-#7-p11.2/2-m-mother 13L0178
12L0130 and
13L0177
EKF-
#7-p11.2/
1-m/r
in cell line:
47,XX,+mar[25]/
46,XX[75]
min(7)(:p12.2q11.21:)[5]/
r(7)(::p12.2
q11.21::)[2]/
r(7;7)(::p12.2
q11.21::p12.2q11.21::)[1]
55.42-63.45 MB
see 07-W-p11.2/1-2 EKF-#7-p11.2/1-m-
mother;
EKF-#7-p11.2/1-m-
father
05P0529
05P0530
05P0531
EKF-
#7-p11.1/
1-r
in cell line:
47,XX,+mar[42]/

46,XX[58]
r(7)(:p11.1q11.21:)[15]/
r(7;7)(:p11.1
q11.21::p11.1q11.21:)[4]/
r(7;7;7;7)
(:p11.1
q11.21::p11.1q11.21:
:p11.1
q11.21::p11.1q11.21:)[1]
FISH-data: RP11-3N2 (63.22 MB) on sSMC
aCGH: 7p11.2-7q11.23 (56,115,171-74,208,699 MB), 2 copies
see 07-W-p11.1/2-1 n.a. 12L0102
EKF-
#7-p11.1/
1-m
in cell line: 47,XX,+mar[15]/
46,XX[81]
interphase: 49 of 500 cells
min(7)(:p11.1q11.1:) see 07-W-p11.1/1-1 n.a. 06PO708
EKF-
#7-p11.1/
2-m
in cell line:
47,XY,+mar[35]/
46,XY[9]
min(7)(:p11.1q11.21:)[10]/
r(7)(::p11.1
q11.21::)[1]/
min(7)(:q11.21-p11.1::p11.1
q11.21:)[9]
see +21 U-28 n.a. 13L0266
EKF-
#7-p11.1/
3-m
in cell line:
47,XY,+mar[5]/
46,XY[43]
min(7)(:q11.1→p11.1:
:p11.1→q11.21:)
mat UPD 7 of normal chrs. 7
see 07-U-21 EKF-#7-p11.1/
3-m-mother
EKF-#7-p11.1/
3-m-father
13L0251
13L0252
13L0253
EKF-
#8-p11.22/
1-m
in cell line:
47,XX,+mar[50]/
46,XX[50]
min(8)(:p11.22→p11.21:
:p11.21→p11.21:
:p11.21→q11.1:
:q11.1→q11.21 or q11.23:)
see 08-W-p11.22/4-1 n.a. 16L0001
EKF-
#8-p11.21~
11.22/
1-r
in cell line:
47,XY,+mar[79]/
46,XY[21]
r(8)(::p11.21~11.22q11.1::)
FISH-data:
42.5-49.5 MB
see 08-W-p11.21~
11.22/1-1
EKF-#8-p11.21~
11.22/1-r-mother;
EKF-#8-p11.21~
11.22/1-r-father
2008B113
2008B112
2008B111
EKF-
#8-p11.21/
1-m/r
in cell line:
47,XX,+mar[17]/

46,XX[34]
min(8)(:p11.21q11.21:)[8]/
min(8)(:p11.21
q11.1:)[3]/
min(8)(:p11.21
q11.1::q11.1p11.21:)[1]/
r(8)(:p11.21
q11.1::q11.1p11.21::q11.21::)[2]
see 08-U-6 n.a. 12L0184
EKF-
#8-p11/
1-m
in cell line:
47,XX,+mar[7]/
46,XX[43]
min(8)(:p11q11:) see 08-O-p11/1-2 n.a. 12L0230
EKF-
#8-p11.1/
1-m
in cell line:
47,XY,+mar[1]/

46,XY[45]
min(8)(:p11.1q11.23:)
FISH-data:
RP13-116A4
at 48.3MB on sSMC
Array: 43.19-54.86 MB
see 08-W-p11/2-1
EKF-#8-p11.1/
1-m-mother
07PO597
07PO596
EKF-
#8-p10/
1-r
in cell line:
47,XY,+r[8]/
46,XY[43]
r(8)(::p10q23.3::) see 08-W-p10/1-1 EKF-#8-p10/
1-r-mother
12L0256
13L0257
EKF-
#9-pter/
1-m
in cell line:
47,XX,+mar[22]/
46,XX[32]
del(9)(q11) see 09-O-p13.1/2-1 n.a. 14L0087
EKF-
#9-p12/
1-m/r
in cell line:
47,XY,+mar[44]/

46,XY[8]

r(9)(::p12q12::)[8]/
min(9)(:p12
q12:)[5]/
r(9;9)(::p12
q12::p12q12::)[2]

see 09-O-p12/3-2
n.a. 2009B022
EKF-
#9-p12/
2-m/r
in cell line:
47,XX,+mar1 or mar2 or mar3[11]/

46,XX[30]
mar1 = min(9)(:p12q10:)
mar2 = min(9)(:p11.1
q12:)
mar3 = r(9)(::p11.1
q12::)
see 09-O-p12/6-1 EKF-#9-p12/
2-m/r-mother

EKF-#9-p12/
2-m/r-father
12L0146
13L0158
13L0159
EKF-
#9-p12/
3-m/r
in cell line:
47,XY,+r[25]/
46,XY[25]
r(9)(::p12q12::)[6]/
min(9)(:p12
q12:)[4]
see 09-O-p12/4-2
n.a.
12L0225
EKF-
#9-p12/
1-r
in cell line:
47,XY,+r[5]/
46,XY[95]
r(9)(::p12q12::) see 09-O-p12/4-1 n.a. 12L0117
EKF-
#9-p11.1/
1-m
in cell line:
47,XX,+mar[1]/
46,XX[49]
min(9)(:p11.1q12:)
see 09-W-p11.1/1-1 n.a. 12L0174
EKF-
#9-p10/
1-m
in cell line:
47,+mar[0]/
46[50]
min(9)(:p10q13:) see 09-O-p10/1-1 n.a. 12L0196
EKF-
#12-p11.1/
1-m
in cell line:
47,XY,+r[7]/
46,XY[43]
min(12)(:p11.1q12:) see 12-W-p11.1/1-1 EKF-#12-p11.22/
1-m-mother
12L0200
13L0087
EKF-
#12-p11.2/
1-m
in cell line:
47,XY,+mar[1]/
46,XY[59]
min(12)(:p11.2→q11:) see 12-O-p11.2/2-1 n.a. 13L0164
EKF-
#12-p11.22/
1-m

in cell line:
47,XX,+mar[26]/
46,XX[24]
min(12)(:p11.22q11:) see 12-O-p11.22/1-1 EKF-#12-p11.22/
1-m-mother
EKF-#12-p11.22/
1-m-father

12L0161
13L0087
13L0237
EKF-
#13/21-q10/
1-i
in cell line:
48,XY,+21,+mar pat[100%]
inv dup(13or21)(q10) see +21-U-38 EKF-#13/21-q11/
1-i-father
2010B211
2010B212
EKF-
#13/21-q10/
2-i

in cell line:
47,XX,+mar pat[32]/

46,XX[11]
in cell line of father: 47,XY,+mar[42]/
46,XY[8]
in cell line of brother:
47,XY,+mar[10]/
46,XY[0]
inv dup(13or21)(q10) see 13/21-O-q10/1-16 EKF-#13/21-q11/
2-i-father;
EKF-#13/21-q11/
2-i-brother
12L0113
12L0114
13L0180
EKF-
#13/21-q10/
3-i
in cell line:
47,XX,+mar mat[26]/
46,XX[4]
inv dup(13or21)(q10)
see13/21-O-q10/1-14 n.a.
12L0162
EKF-
#13/21-q10/
4-i

in cell line:
47,XY,+mar[58]/
46,XY[1]
inv dup(13or21)(q10)
see 13/21-O-q10/1-21 n.a. 13L0246
EKF-
#13/21-q10/
5-i
in cell line:
47,XX,+mar mat[39]/

46,XX[11]
in cell line of mother:
 47,XX,+mar[20]/
46,XX[25]
inv dup(13or21)(q10) see 13/21-O-q10/1-17 EKF-
#13/21-q11/
5-i-mother
12L0170
12L0171
EKF-
#13/21-q11/
1-i
in cell line:
47,XX,+mar[0]/
46,XX[50]
inv dup(13)(q11) or
inv dup (21)(q11.1)
see 13/21-O-q11/2-14
n.a. 12L0126
EKF-
#13/21-q11/
2-i
in cell line:
47,XX,+mar[35]
inv dup(13)(q11) or
inv dup (21)(q11.1)
see 13/21-O-q11/2-19 n.a. 15L0003
EKF-
#13/21-q11/
1-m
in cell line:
47,XX,+mar[36]/
46,XX[11]
min13 (pter→q11:) or min21(pter→q11.1:) see 13/21-O-q11/1-4 n.a. 14L0243
EKF-
#14-q11/
1-i
in cell line:
47,XX,+mar[14]/
46,XX[26]
inv dup(14)(q11) see 14-O-q11/1-2 EKF-#14-q11/
1-i-mother
EKF-#14-q11/
1-i-father
12L0147
13L0219
13L0220
EKF-
#14-q11.1/
1-i
in cell line:
47,XX,+mar[23]/
46,XX[19]
inv dup(14)(q11.1) see 14-O-q11.1/1-10 n.a. 06P0430
EKF-
#14-q11.1/
2-i
in cell line:
47,XX,+mar[100%]

inv dup(14)(q11.1)
see 14-O-q11.1/1-14 n.a. 07PO567
EKF-
#14-q11.1/
3-i
in cell line:
47,XY,+mar[44]/
46,XY[6]
inv dup(14)(q11.1) see 14-O-q11.1/1-29 n.a. 11L004
EKF-
#14-q11.1/
4-i
in cell line:
47,XX,+mar[11]/
46,XX[34]
inv dup(14)(q11.1) see 14-O-q11.1/1-31 n.a. 12L0086
EKF-
#14-q11.1/
5-i

in cell line:
47,XY,+mar[48]
inv dup(14)(q11.1) see 14-O-q11.1/1-11 n.a. 12L0134
EKF-
#14-q11.1/
6-i

in cell line:
47,XX,+mar mat[48]
inv dup(14)(q11.1) see 14-O-q11.1/1-30
n.a. 12L0222
EKF-
#14-q11.1/
7-i
in cell line:
47,XY,+mar[57]

inv dup(14)(q11.1) see  14-O-q11.1/1-38 n.a. 14L0044
EKF-
#14-q11.1/
8-i
in cell line:
47,XX,+mar[100%]
inv dup(14)(q11.1)
see  14-O-q11.1/1-44 n.a. 15L0166
EKF-
#14-q11.1/
9-i
in cell line:
47,XY,+mar[100%]
inv dup(14)(q11.1) see 14-O-q11.1/1-48
n.a. 16L0123
EKF-
#14-q11.1/
10-i
in cell line:
47,XY,+mar[100%]
inv dup(14)(q11.1) see 14-O-q11.1/1-50 n.a. 18L0005
EKF-
#14-q11.1/
11-i
in cell line:
47,XX,+mar[99]/
46,XX[1]
inv dup(14)(q11.1) see 14-O-q11.1/1-51 n.a. 18L0007
EKF-
#15-N/
1-i
in cell line:
47,XX,+mar[1]/

46,XX[51]
inv dup(15)(qterq24.1:
:q24.1
qter)
see 15-N-qt23/1-2 n.a. 05P0753
EKF-
#15-q10/
1-i
in cell line:
47,XY,+mar[90]/
46,XY[10]
inv dup(15)(q10) see 15-O-q10/1-7 n.a. 12L0090
EKF-
#15-q11/
1-m
in cell line:
47,XX,+mar[58]/

46,XX[42]
min(15)(:p11q11:) see 15-O-q11/4-2 n.a. 12L0087
EKF-
#15-q11/
1-i
in cell line:
47,XY,+mar[9]/
46,XY[91]
inv dup(15)(q11) see 15-O-q11/1-1 n.a. 12L0105
EKF-
#15-q11/
2-i
in cell line:
47,XY,+mar[62]/
46,XY[2]

inv dup(15)(q11)
see 15-O-q11/1-43 n.a. 13L0103
EKF-
#15-q11.1/
1-r
in cell line:
 47,XX,+mar[26]/

46,XX[74]
r(15)(::p11.1q11.1::) see 15-W-q11.1/1-1
n.a.
12L0094
EKF-
#15-q11.1/
1-m
in cell line:
47,XX,+mar[0]/
46,XX[50]
min(15)(:p11.1q11.1:) see 15-U-24
n.a. 12L0123
EKF-
#15-q11.1/
1-i
in cell line:
47,XX,+mar[19]/

46,XX[81]
inv dup(15)(q11.1)
see 15-O-q11.1/1-22
n.a. 07PO019
EKF-
#15-q11.1/
2-i
in cell line:
47,XX,+mar[28]/

46,XX[72]
inv dup(15)(q11.1)

see 15-O-q11.1/1-10
n.a. 12L0091
EKF-
#15-q11.1/
3-i
in cell line:
47,XX,+mar[99]/

46,XX[1]
inv dup(15)(q11.1)
see 15-O-q11.1/1-21 n.a.
12L0112
EKF-
#15-q11.1/
4-i
in cell line:
47,XY,+mar[51]

inv dup(15)(q11.1) see 15-O-q11.1/1-62 n.a. 12L0183
EKF-
#15-q11.1/
5-i

in cell line:
47,XY,+mar[41]/
46,XY[6]
inv dup(15)(q11.1) see 15-O-q11.1/1-49 n.a. 12L0169
EKF-
#15-q11.1/
6-i
in cell line:
47,XX,+mar mat[7]/
46,XX[46]
inv dup(15)(q11.1) see mother of
15-O-q11.1/1-11
n.a. 12L0148
EKF-
#15-q11.1/
7-i
in cell line:
47,XY,+mar[28]/
46,XY[21]
inv dup(15)(q11.1) see 15-W-q11.1/3-2 n.a. 12L0133
EKF-
#15-q11.1/
8-i

in cell line:
47,XX,+mar[48]/
46,XX[0]
also in son and daughter cell lines 100% sSMC

inv dup(15)(q11.1)
see 15-O-q11.1/1-16
mother of two normal children with same sSMC
EKF-#15-q11.1/8-i-son
EKF-#15-q11.1/
8-i-daugther
12L0212
12L0213
12L0214
EKF-
#15-q11.1/
9-i

in cell line:
47,XX,+mar[50/
46,XX[0]
inv dup(15)(q11.1) see 15-O-q11.1/1-77 n.a. 12L0142
EKF-
#15-q11.1/
10-i
in cell line:
47,XX,+mar[50]
inv dup(15)(q1?1.1) see 15-O-q11.1/1-80 n.a. 12L0143
EKF-
#15-q11.1/
11-i
in cell line:
47,XY,+mar[57]/
46,XY[1]
inv dup(15)(q11.1)
see 15-O-q11.1/1-85
n.a. 12L0221
EKF-
#15-q11.1/
12-i
in cell line:
47,XX,+mar[46]
inv dup(15)(q11.1) see 15-O-q11.1/1-81 n.a. 12L0305
EKF-
#15-q11.1/
13-i
in cell line:
47,XX,+mar[43]/
46,XX[10]
inv dup(15)(q11.1) see 15-O-q11.1/1-84 n.a. 13L0258
EKF-
#15-q11.1/
14-i
in cell line:
47,XY,+mar[63]/
46,XY[1]
inv dup(15)(q11.1) see 15-O-q11.1/1-98 n.a. 13L0187
EKF-
#15-q11.1/
15-i
in cell line:
47,XX,+mar[3]/
46,XX[43]
inv dup(15)(q11.1) see 15-O-q11.1/1-99 n.a. 13L0245
EKF-
#15-q11.1/
16-i
in cell line:
47,XX,+mar[100%]
in father: sSMC in 96%
inv dup(15)(q11.1) see 15-O-q11.1/1-101 EKF-#15-q11.1/
16-i-father
14L0134
14L0143
EKF-
#15-q11.1/
17-i
in cell line:
47,XX,+mar[31]/
46,XX[19]
inv dup(15)(q11.1) see 15-O-q11.1/1-65 n.a. 12L0124
EKF-
#15-q11.1/
18-i

in cell line:
47,XX,+mar[2]/
46,XX[23]

inv dup(15)(q11.1)
see 15-O-q11.1/1-107 n.a.
16L0169
EKF-
#15-q11.1/
19-i

in cell line:
47,XX,+mar[25]
inv dup(15)(q11.1)
see
15-O-q11.1/1-114
n.a. 17L0188
EKF-
#15-q11.1/
20-i

in cell line:
47,XY,+mar[99]/
46,XY[1]
inv dup(15)(q11.1)
see 15-O-q11.1/1-115 n.a. 18L0006
EKF-
#15-q11.1/
21-i

47,XY,+mar[100%]
inv dup(15)(q11.1)
see 15-O-q11.1/1-127 n.a. 18L0141
EKF-
#15-q11.1-q13/
1-i

in cell line:
47,XX,+mar[1]/
46,XX[42]
der(15)(:q14q13::q14p11.1:
:p11.1
q14::q13q14:)
FISH-data: UBE3A at 23.2MB on sSMC
see 15-W-q14/4-1 EKF-#15-q11.1-
q13/1-i-mother;
EKF-#15-q11.1-
q13/1-i-father
2009B052
2009B050
2009B051
EKF-
#15-q11.2/
1-i
in cell line:
47,XY,+mar[15]/
46,XY[85]
inv dup(15)(q11.2) see 15-O-q11.2/1-6 n.a. 2008B026
EKF-
#15-q11.2/
2-i
in cell line:
47,XY,+mar[97]/
46,XY[3]
inv dup(15)(q11.2)
FISH-data: RP11-307C10 at 20.6MB on sSMC; RP11-131I21 at 22.73Mb not on sSMC
see 15-O-q11.2/1-13 n.a. 12L0101
EKF-
#15-q11.2/
3-i
in cell line:
47,XX,+mar[55]
inv dup(15)(q11.2) see 15-O-q11.2/1-19 n.a. 15L0055
EKF-
#15-q11.2/
4-i
in cell line:
47,XY,+mar[100%]

inv dup(15)(q11.2) see 15-O-q11.2/1-23 n.a. 16L0199
EKF-
#15-q11.2~12/
1-i
in cell line:
47,XX,+mar[96]/
46,XX[4]
inv dup(15)(q11.2~q12)
see 15-O-q11.2~12/1-2 n.a. 06P0226
EKF-
#15-q11.2~12/
2-i
in cell line:
47,XY,+mar[10]/
46,XY[45]
inv dup(15)(q11.2~q12) see 15-O-q11.2~12/1-3 n.a. 13L0138
EKF-
#15-q12/
1-i
in cell line:
47,XY,+mar[100]
inv dup(15)(q12)
FISH-data: RP11-171C8 at 23.0MB on sSMC
see 15-W-q12/1-1 n.a. 12L0141
EKF-
#15-q12~13/
1-i
in cell line:
47,XY,+mar[49]/
46,XX[1]
inv dup(15)(q12~13)
see 15-CWw-148 n.a. 12L0258
EKF-
#15-q13/
1-i
in cell line:
47,XX,+mar[19]/
46,XX[32]
inv dup(15)(q13)
FISH-data: SNRPN at 22.8MB on sSMC
see 15-W-q13/1-11 n.a. 12L0265
EKF-
#15-q13.1/
1-r
in cell line:
47,XX,+mar[30]/
46,XX[19]
r(15)(::p11.2q13.1::)
FISH-data: SNRPN at 22.8MB on sSMC
see 15-O-q13.1/1-1 n.a. 12L0269
EKF-
#15-q14/
1-i
in cell line:
47,XX,+mar[49]/
46,XX[1]
inv dup(15)(q14) see 15-Caw-55
n.a. 12L0131
EKF-
#15-q14
q13.2q13.3/
1-i
in cell line:
48,XY,+marx2[50]
der(15)(pterq13.1~13.2: :q13.3q14::q14q13.3: :q13.1~13.2pter) see 15-W-q13.3+ q13.2+q14/1-1 EKF-#15-q14
q13.2q13.3/
1-i-mother;
EKF-#15-q14
q13.2q13.3/
1-i-father
11L369
11L370
11L371
EKF-
#15compl#13/
1-m
in cell line:
46,XY,t(13;15)(p11.2;q13.2)
see 15-U-215 n.a. 12L0190
EKF-
#16-p11.2/
1-r
in cell line:
47,XY,+mar[0]/

46,XY[56]
r(16)(::p11.2q12.1::)
aCGH: 9,875,000-35,005,000 MB
see 16-W-p11.2/3-3 EKF-#16-p11.2/
1-r-mother
EKF-#16-p11.2/
1-r-father
12L0138
13L0248
13L0247
EKF-
#16-p11.2/
1-m
in cell line:
47,XX,+mar[25]/
46,XX[25]
min(16)(:p11.2→q11.1:) see 16-O-p11.2/1-2 n.a. 14L0117
EKF-
#16-p11.1/
1-m

in cell line:
47,XY,+mar[8]/
46,XY[92]
min(16)(:p11.1q12.1:) see 16-O-p11.1/4-2 n.a.
06PO100
2005B290
EKF-
#16-p11.1/
2-m
in cell line:
47,XX,+mar[50%]/
46,XX[50%]
min(16)(:p11.1→q11.1:) see 16-O-p11.1/5-4 n.a. 14L0168
EKF-
#16-p11.1/
3-m
in cell line:
47,XY,+mar[2]/
46,XY[31]
min(16)(:p11.1→q11.1~11.2:) see 16-O-p11.1/7-1 n.a. 15L0135
EKF-
#17-p11.1/
1-i
in cell line:
47,XY,+mar[55]/
46,XX[5]

dic(17)(:p11.1→q11.1::q11.1→q11.2:)
see 17-U-4 n.a.
12L0186
EKF-
#18-pter/
1-i

in cell line:
47,XX,+mar[99]
/
46,XX[1]
i(18p)
pter-0.36MB of q-arm
see 18-Wi-139
n.a. 12L0053
EKF-
#18-pter/
2-i

47,XX,+mar[100%] i(18p)
see 18-Wi-360
n.a. J19-38616-
SU135
EKF-
#18-p11.21/
1-m
in cell line:
47,XY,+mar[93]/

46,XY[57]
FISH: min(18)(:p11.21q11.1:)
array + FISH:
min(18)(:p11.22p11.21:)
FISH-data: RP11-151D11(13.08MB) on sSMC
array: 13.99MB - centromere
see 18-O-p11.21/1-2 n.a. 05P0294
EKF-
#18-p11.21/
2-m

in cell line:
47,XX,+mar[16]/

46,XX[22]
FISH: min(18)(:p11.21q11.1:)
breakpoint in 18p between clone RP11-794M8 (13.03MB) and RP11-411B10 (13.99MB)
see 18-O-p11.21/1-3 n.a. 12L0132
EKF-
#18-p11.1/
1-m
in cell line:
47,XX,+mar[24]/
46,XX[33]

min(18)(:p11.1→q11.1~11.2:)
RP11-10G8 present on sSMC
see 18-O-p11.1/2-1 n.a. 16L0205
EKF-
#18compl#8/
1-m
in cell line:
47,XY,+mar[100]
der(18)t(8;18)(p23.2~23.1;q11.1) see 18-U10 n.a. 06P0222
EKF-
#18-q11.1/
1-i

in cell line:
47,XY,+mar[55]
i(18)(p10) see 18-Wi-143 EKF-#18-q11.1/
1-i-mother;
EKF-#18-
q11.1/
1-i-
father
2007B279
2007B277
2007B278
EKF-
#19-p13.1/
1-m

in cell line:
47,XY,+mar[9]/
46,XY[47]
min(19)(:p13.11~13.12q12:) see 19-W-p13.1/3-1 n.a.
12L0085
EKF-
#19-p13.11/
1-m
in cell line:
47,XX,+mar[0]/
46,XX[31]

min(19)(:p13.11q12:) 
FISH-data:
26.7-at least to 33.3MB
see 19-U-7 n.a. 05P0067
EKF-
#19-p13.11/
2-m
in cell line:
47,XX,+mar[21]/
46,XX[34]
min(19)(:p13.11→q11~12:)
FISH-data: RP11-22G10 (22.98MB) on sSMC

see 19-O-p13.11/1-1 n.a. 12L0140
EKF-
#19-p13.11/
2-r
in cell line:
47,XX,+mar[0]/
46,XX[50]
min(19)(:p13.11q11:)[3]/
r(19)(::p13.11
q11::)[9]/
r(19)(::p13.11
q11::p13.11q11::)[2]
FISH-data: RP11-22G10 (22.98MB) on sSMC
aCGH: 17.50-33.59
see 19-O-p13.11/3-1 n.a. 2008B073
EKF-
#19-p12/
1a-m

in cell line:
47,XY,+mar[11]/
46,XY[50]
min(19)(:p12q12:)
size in p 2.59MB (= position 25.91 MB) , in q 2.3 MB (= position 32.4MB)
see 19-W-p12/2-1 EKF-#19-p12/
1-m-mother
EKF-#19-
p12/
1-m-
father

12L0089
13L0298
13L0134
EKF-
#19-p12/
1b-m

in cell line:
47,XY,+mar[5]/
46,XY[50]
min(19)(:p12q12:) see 19-U-20 n.a. GGB0358M, 2236
EKF-
#19-p12/
2-m

in cell line:
47,XY,+mar[4]/
46,XY[48]
min(19)(:p12q13.11~13.12:)
size in p: RP11-22G10 in subcenM present on sSMC (22.98 MB - no signal in p on array), in q according to array: sSMC goes to 36.3 MB
see 19-W-p12/5-1 n.a. 12L0127
EKF-
#19-p12/
3-m

in cell line:
47,XY,+mar[9]/
46,XY[51]
min(19)(:p12q13.1?1:) see 19-W-p12/5-2 n.a. 12L0253
EKF-
#19-p11.1/
1-m

in cell line:
47,XX,+mar[0]/
46,XX[50]
min(19)(:p11.1q13.1:)
FISH-data: RP11-14D17 (36.90MB) on sSMC
see 19-O-p11/1-1 n.a. 05P0277
EKF-
#20-p11.22
~11.21/1-m

in cell line:
47,XX,+mar[7]/

46,XX[45]
min(20)(:p11.23→q11.22:) see 20-W-p11.22/1-2 n.a. 12L0164
EKF-
#20-p11.1/
1-m/r
in cell line:
47,XX,+mar[1]/
46,XX[55]
47,XX,+min(20)(:p11.1q11.23:)[18]/47,XX,+min(20)(:q11.23p11.1::p11.1q11.23:)[7]/
47,XX,+r(20)(::p11.1
q11.23::p11.1q11.23::)[3]/46,XX[2]
see 20-W-p11.1/1-1 n.a.
12L0257
EKF-
#21-q11.2/
1-m
in cell line:
47,XX,+mar[5]/
46,XX[20]

min(21)(pterq11.2:)
see 21-O-q11.2/1-3 n.a. GGB04574F, 798
EKF-
#21-q11.2/
1-i
in cell line:
47,XY,+mar[149]
/
46,XY[1]
inv dup(21)(q11.2)
FISH-data: RP11-89H21 (14.85MB) on sSMC

see 21-O-q11.2/2-1
n.a. 12L0092
EKF-
#21-q11.2~
21.1/
1-m
in cell line:
47,XY,+mar[0]/
46,XY[92]
min(21)(pterq11.2~21.1:) see 21- W-q11.2~
21.1/ 1-2
EKF-#21-q11.2~21.1/
1-m-mother;

EKF-#21-q11.2~21.1/
1-m-father
06P0503 06P0503-A
07P0285
07P0284
EKF-
#22-q11.1/
1-m
in cell line:
47,XX,+mar[8]/
46,XX[44]
min(22)(:p11.1q11:)
maternal UPD 22
see 22-O-q11/2-1 EKF-#22-q11.1/
1-m-mother;
EKF-#22-q11.1/
1-m-father
12L0093
13L0215
13L0214
EKF-
#22-q11.1/
2-m
in cell line:
47,XX,+mar[11]/
46,XX[38]
min(22)(:p13q11.1:) see 22-O-q11.1/2-1 n.a. 13L0163
EKF-
#22-q11.1/
3-m
in cell line:
47,XX,+mar[74]/
46,XX[26]
min(22)(:p12→q11.1:) see 22-O-q11.1/2-3 EKF-#22-q11.1/
3-m-mother;
EKF-#22-q11.1/
3-m-father
14L0224
14L0225
14L0226
EKF-
#22-q11.1/
1-i
in cell line:
47,XX,+mar[44 or 9]/
46,XX[4 or 21]
inv dup(22)(q11.1) see 22-O-q11.1/1-11 n.a. 2007B188
07PO490
EKF-
#22-q11.1/
2-i
in cell line:
47,XY,+mar pat[40]/
46,XY[11]
inv dup(22)(q11.1) see 22-O-q11.1/1-14 n.a. 2008B140
EKF-
#22-q11.1/
3-i
in cell line:
47,XY,+mar[46]/
46,XY[4]
inv dup(22)(q11.1) see 22-O-q11.1/1-13 n.a. 2008B136
EKF-
#22-q11.1/
4-i
in cell line:
47,XX,+mar[51]
inv dup(22)(q11.1) see 22-O-q11.1/1-21 n.a. 2008B246
EKF-
#22-q11.1/
6-i
in cell line:
47,XX,+mar mat[50]
in cell line of mother:
47,XX,+mar[50]
inv dup(22)(q11.1) see 22-O-q11.1/1-22 EKF-#22-q11.1/
6-i-mother;
12L0104
12L0103
EKF-
#22-q11.1/
7-i
in cell line:
47,XY,+mar[100%]
inv dup(22)(q11.1) see 22-O-q11.1/1-38
n.a. 11L351
EKF-
#22-q11.1/
8-i
in cell line:
47,XY,+mar mat[50]
in cell line of mother:
47,XX,+mar[47]/
46,XX[2]
inv dup(22)(q11.1) see 22-O-q11.1/1-23 EKF-#22-q11.1/
8-i-mother;
12L0108
12L0109
EKF-
#22-q11.1/
9-i
in cell line:
47,XY,+mar mat[25]/
46,XY[24]
in cell line of mother:
47,XX,+mar[43]/
46,XX[7]
inv dup(22)(q11.1)
see 22-O-q11.1/1-33
EKF-#22-q11.1/
9-i-mother;
12L0115
12L0116
EKF-
#22-q11.1/
10-i
in cell line:
47,XX,+mar[100%]
inv dup(22)(q11.1) see 22-W-q11.1/1-5 n.a. 12L0118
EKF-
#22-q11.1/
11-i
in cell line:
47,XX,+mar[53]
inv dup(22)(q11.1) see 22-O-q11.1/1-31 n.a. 12L0121
EKF-
#22-q11.1/
12-i

in cell line:
48,XX,+marx2[1]/
47,XX,+mar[25]/
46,XX[20]
inv dup(22)(q11.1) see 22-O-q11.1/1-58 n.a. 13L0261
EKF-
#22-q11.1/
13-i
in cell line:
47,XY,+mar[33]/
46,XY[17]
inv dup(22)(q11.1) see 22-O-q11.1/1-62 n.a. 14L0108
EKF-
#22-q11.21/
1-i
in cell line:
47,XX,+mar[48]
/
46,XX[2]
inv dup(22)(q11.21) see 22-Wces-5-93 n.a. 05PO209
EKF-
#22-q11.21/
2-i
in cell line:
47,XY,+mar[26]/
46,XY[28]
inv dup(22)(q11.21) see 22-O-q11.21/2-1 n.a. 12L0088
EKF-
#22-q11.21/
3-i
in cell line:
47,XY,+mar[1]/
46,XY[99]
inv dup(22)(q11.21)
see 22-Wces-5-208 n.a. 16L0114
EKF-
#22-q11.21/
4-i
in cell line:
47,XY,+mar[100%]
inv dup(22)(q11.21)
see 22-Wces-7-1 n.a. 18L0035
EKF-
#22-q11.21/
1-m
in cell line:
47,XX,+mar[20%]/
46,XX[80%]
min(22)(:p11.2→q11.21:)
aCGH: arr[hg19]: break in 18,848,020

see 22-O-q11.21/4-5 n.a. 16L0181
EKF-
#22-q12.1/
1-m
in cell line:
47,XY,+mar[41]/
46,XY[9]
min(22)(pterq12.1:)
FISH-data:
pter to 24.6MB
see 22-W-q12.1/1-1 n.a. 06P0775
EKF-
#22compl#11/
1-m
in cell line:
47,XX,+mar[100]
der(22)t(11;22)
(q23;q11.2)
see 22-Wder-143 EKF-#22compl#11
/1-m-mother;
EKF-#22compl#11/1-m-father;
12L0098
12L0099
12L0100
EKF-
X-p11.3/
1-m/r
in cell line:
45,X[54]
/
46,X,+marx2[1]

r(X)(::p11.3q21.1::)[2]/
min(X)(:p11.3
q21.1:)[3]/
min(X)(:p11.21
q11.2:)[2]
see minX-p11.3/3-1
n.a. 12L0139
EKF-
Y-p11.2/
1-m
in cell line:
45,X[41]/
46,X,mar[4]
r(Y) = min(Y)(:p11.2q11.1:) see m-minY-p11.2/1-1 n.a. 12L0264
EKF-
Y-q11.21/
1-i
in cell line:
45,X[13]/
46,X,der(Y)[43]
idic(Y)(q11.221)[103]/
del(Y)(q11.21~q11.221)[3]/
der(Y)(pter→q11.21~q11.221:
:q11.221→q11.221:)
see f-iY-q11.21/1-1 n.a. 13L0092
EKF-
Y-q11.22/
1-i
in cell line:
45,X[19]/
46,X,der(Y)[45]
inv dup(Y)(q11.221)[89]/
inv dup(Y)(q11.221)x2[8]/
der(Y)(pter→q11.21::q11.21→q11.21:
:q11.221→q11.222::q11.222→q11.221:
:q11.21→q11.21::q11.21→pter)x2[24]
see m-iY-q11.22/1-3 n.a. 12L0110
EKF-
Y-q11.2/
1-r
in cell line:
45,X[5]/
46,XY[10]/

46,X,der(Y)[34]
inv dup(Y)(q11.223)[10]/
r(Y)(::p11.32→p11.2:
:p11.2→p11.2::p11.2→p11.2:
:p11.1→q11.223::p11.31→p11.31::),
r(Y)(::p11.32→p11.2::p11.2→p11.2:
:p11.2→p11.2::p11.1→q11.21:
:q11.21→q11.21::q11.221→?q11.223:
:p11.31→p11.31::)
see m-rY-p11.32/5-1 n.a. 13L0223
EKF-
mult#4-#18/
1-i/m
in cell line:
48,XX,+mar1,+mar2[3]/

47,XX,+mar1 or 2[19]/
46,XX[32]
min(4)(:p12q12:); r(18)(::p11.21q11.2:
:p11.21
q11.2::)[2]/
inv dup(18)(:p11.1
q11.1::q11.1p11.1:)[4]/
min(18)(:p11.21
q11.1::q11.1p11.1:)[4]
chr 4: 48.34-59.71
chr. 18: 13.17-18.73
see mult 2-18 n.a. 05P0163
EKF-
mult#5-#6/
1-m/r
in cell line:
47,XX,+mar[27]/

46,XX[27]
r(5)(::p11q11.1::q1213.1~3::)
40.66MB to 47.10MB
min(6)(:p11.1
q11.2:);
57.10MB to 64.87MB
see mult 2-19 n.a. 2010B194
EKF-
mult#8-#21/
1-m/r
in cell line:
49,XY,mar2x2[0]/

48,XY,mar1,mar2[12]/
47,XY,mar1[33]/
46,XY[106]
r(8)(:p12q11.1::q11.1p21.1:),
min(8)(:p11.22
q11.21::q11.21p21.1::p21.1
p11.22:) [70%],
min(21)(:p11.1
q21.3:) [30%]
chr 8: 28.63-48.74 MB
chr 21: 13.30-28.90 MB
see mult 2-21 n.a. 05P0208
EKF-
mult#4-#8-#11/
1-r
in cell line:
48,XY,+2mar[1]/
47,XY,+mar[41]/
46,XY[9]
r(4)(::p12q12::)[?]
min(8)(:p11.21→q11.21::)[6]
min(8)(:p21.1→p12: :p11.21→q11.21:)[14]
40.08-53.56 MB (hg19)
r(11)(::p11.12
q11.1::)[?]
acc. to NGS sSMC(8) is a
mar(8)(:p11.21→q11.23:
:q12.1q12::q12q12:) spanning
chr8:g[:53561524::GCCCTAAGGAATCTCC:
:60002688_60002774::TGG:
:55759348_55759565:
:TGATGTGTCACCTTGCTTTTAGATCTGAAGGTGA:
:40082798:]

 see mult 3-5 EKF-mult#4-
#8-#11/1-r-
mother; EKF-mult#4-
#8-#11/1-r-father
2010B110
1010B108
2010B109
EKF-
N-acro/
1-i
47,XY,+mar[100%] inv dup (acro)(p10) see acro-O-10 n.a. 18L0210
EKF-
N/
1-i
in cell line:
47,XY,+mar[100%]
mar stains only with a reverse painting probe of itself see u-W-1 n.a. (provided by Dr. Caroline Mackie Ogilvie, UK)
EKF-
N/
1-mar
in cell line:
47,XY,+mar[90]/
46,XY[10]
der(?)
contains material from 8q22.3-8q23.1, 9q33.3-9q34.11, 2 regions from 14q21.1, 15q21.2 and 21q21.1
see u-Uc-2 n.a. 18L0070


Nomenclature of the cell lines in the Else Kröner-Fresenius cellbank


Explanation using following example: EKF-#1-p11.1/1-r

EKF Else Kröner-Fresenius-foundation
#1 to #22, X, Y chromosome sSMC is derived from
p11.1 distal chromosomal breakpoint
/1- number of case(es) with identical breakpoints
i/m/r/mar shape of sSMC as inverted duplicated, centric minute, ring or marker = undefined
 

other abbreviations used:

compl
complex (rearranged) sSMC
mult multiple sSMC
N neocentric