ChromosOmics - About the Author

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Thomas Liehr (2023)
web-presence: https://cs-tl.de/Start.html


Created by Dr. Thomas Liehr (PhD),
affiliation: Institute of Human Genetics, 07740 Jena, Germany;
e-mail: Thomas.Liehr@med.uni-jena.de or LiehrT@web.de
Publications of Thomas Liehr
Articles
List of journals already published in - HERE.
List of species studies with colleagues - HERE.


Abbreviations for Research Topics

CG = Clinical genetics; EVO = evolution; HET = heterochromatin; INT = interphase and chromosome structure; M = method / probeset development; PRE = prenatal; sSMC = small supernumerary marker chromosomes; TCG = tumorcytogenetics; UPD = uniparental disomy

2026

Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
941 N dos Santos, FdMC Sassi, RZ dos Santos, CAG Goes, RLR de Moraes, F Porto-Foresti, T Liehr, MdB Cioffi, R Utsunomia.
Molecular divergence and genomic composition of B chromosomes in the fish Cyphocharax modestus (Characiformes, Curimatidae).
Sci Rep 2026, 16:28198. 		4.900 EVO
940 T Liehr, Fuchs S.
Unanswered questions when human karyotyping shows a supernumerary chromosome.
Heredity (Edinb): 2026, 135:633-637. 		2.600 sSMC; CG
939 M Bisba, E Louizou, K Tzanakis, T Liehr, S Vittas.
Prenatal diagnosis of a low-level mosaic small supernumerary marker chromosome (sSMC): Early postnatal clinical follow-up.
OBM Genetics 2026, 10: 353. 		n.a. sSMC
938 GA Toma, EHC de Oliveira, KD Maurício, LA Carneiro, T Liehr, MdB Cioffi.
The role of satellite DNAs in repeatome organization and sex chromosome evolution in the owl monkey Aotus infulatus and congeneric species.
Biol Direct 2026, 21:156. 		5.500 EVO
937 T Liehr.
Cancer type specific copy number variants are identical over species borders.
Reports of NAS Ra 2026; 126:4. 		n.a. TCG
936 PG Setti, A Moura de Oliveira, S Ferguson Motheo, OG Gonçalves de Almeida, T Liehr, M de Bello Cioffi.
 Concanavalin A protocol for felid lymphocyte culture and chromosome preparation.
Int J Mol Sci 2026, 27:6662. 		5.600 M
935 A Cornejo Müller, T Liehr, P Balakrishnan, DT Keller, KS Hardt, SK Schröder-Lange, S Kankel, EM Buhl, C Liedtke, R Weiskirchen.
Establishment and characterization of the murine liver tumor cell line ∆CN60 with conditional caspase-8 and IKKγ/NEMO inactivation and a hepatocyte-biliary, progenitor-like phenotype.
Cells 2026, 15, 1325. 		5.900 TCG
934 T Liehr, M Rinčić.
ChromoSomics: A new home for chromosomic-related research.
ChrSomics 2026, 1:1. 		n.a. other
933 T Liehr.
Inclusion of human centromeres in genomic browsers – will it finally come?
J Transl Genet Genom 2026; 10:156-159. 		1.500 HET
932 F Sheth J Shah, M Muranjan, T Liehr, N Padutsch, S Mane, SME Ng, P Li, M Desai, H Kansara, JJ Sheth, H Sheth.
Genotype-phenotype correlation through breakpoint characterization of a genomically balanced complex chromosomal rearrangement using long read sequencing.
Am J Med Genet 2026; 200:1673-1681. 		1.700 CG
931 H Bouchahta, N Benyahya, Z EL Amrani, F Ouboukss, T Liehr, SC Elalaoui, IM Carreira, Y Doubaj, A Natiq, L Sbabou.
Clinical and molecular cytogenetic characterization of a de novo 3q26.33-q28 duplication: Case report and literature review.
OBM Genetics 2026, 10:341. 		n.a. CG
930 S Pires, I França, P Oliveira, P Jorge, T Liehr, N Oliva-Teles.
The role of satellite DNA-enriched heterochromatic variants in reproductive disorders: Insights from standardized cytogenetic analysis.
Chromosome Res 2026, 34:9. 		1.950 HET
929 ML Chong, B Burssed, Z Chen, J Wen, E Ng, B Szewczyk, G Wang, KP Chua, T Liehr, Y Zou, JB Murry, F Sheth, P Li, MI Melaragno.
Unravelling ring chromosome structures and formation mechanisms by short read and long-read genomic sequencing.
 Genet Med Open 2026, 4:103475. 		6.200 CG
928 F Kavaja, T Liehr, G Temaj.
Medical genetic architecture of obesity and advances in precision pharmacotherapy: A comprehensive review.
Acta Biochim Pol 2026, 73:15484. 		2.200 CG
927 E Arlt, N Bley, A Rausch, S Hauser, J Pietzsch, D Misiak, T Liehr, S Kankel, T Dautz, L Dreher, X Kǒng, H Kielstein, I Bazwinsky-Wutschke.
Sex determines the natural killer cell-mediated immunity against pancreatic cancer.
Oncoimmunology 2026, 15: 2645298. 		6.200 TCG
926 T Liehr.
Challenges and ethical issues related to non-invasive prenatal testing (NIPT).
OBM Genetics 2026, 10:2601332. 		n.a. CG
925 DY Asar, S Kankel, DT Keller, KS Hardt, EM Buhl, T Liehr, R Weiskirchen.
Comprehensive cytogenetic and genomic profiling of the murine AML12 (Alpha Mouse Liver 12) hepatocyte cell line.
Cells 2026, 15:390. 		5.900 TCG
924 M Rincic, J Kopic, V Klein, Z Krsnik, T Liehr, S Giesselmann, I Kurth, F Kraft.
Structural variations in evolutionary novel genomic regions: New insights into neurodevelopmental disorders by long-read DNA sequencing.
Mol Med 2026, 32:17. 		8.300 CG, EVO
923 A Batalli, T Liehr, G Temaj.
Behçet's disease: A comprehensive overview of symptoms, pathology, genetics, and treatment.
J Mother Child 2026, 30:1-10. 		1.100 CG

2025

Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
922 Y Bahap, MA Ergun, E Tug, T Liehr, M Yirmibes Karaoguz.
Fluorescence in situ hybridization analysis can reveal subtle chromosomal rearrangements in pericentromeric regions of acrocentric chromosomes in patients with reproductive failure.
Cytogenet Genome Res 2025, 165:307-315. 		2.000 CG
921 JAD Vidal, D Charlesworth, WJ Ma, Q Zhou, R Utsunomia, AJB Gomes, AB da Silva, F Porto-Foresti, T Liehr, MB Cioffi.
Investigating the evolution of large meiotic rings of multiple X and Y sex chromosomes in two Leptodactylus frog species (Anura, Leptodactylidae).
Commun Biol 2025, 8:1636. 		5.300 EVO
920 DD Luis, T Liehr, S Kankel, A Weise, C Pentzold, EM Buhl, KS Hardt, DT Keller, SK Schröder-Lange, R Weiskirchen.
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Front Cell Dev Biol 2025, 13:1648639. 		5.300
 TCG
919 GA Deon, T Ezaz, AJ Baia Gomes, JH Forte Stornioli, PG Setti, F Porto-Foresti, R Utsunomia, T Liehr, RZ dos Santos, EHC de Oliveira, MdB Cioffi.
Repetitive DNAs and karyotype evolution in Phyllostomid bats (Chiroptera: Phyllostomidae).
Biomolecules 2025, 15:1248. 		5.600 EVO
918 T Liehr.
Incomplete trisomic rescue by chromothripsis leads to small supernumerary marker chromosomes. Methods Mol Biol 2025, 2968:457-463. 		0.423 sSMC
917 LF Buitkamp, T Liehr, S Kankel, EM Buhl, KS Hardt, DT Keller, SK Schröder-Lange, R Weiskirchen.
Comprehensive genetic and molecular characterization confirms hepatic stellate cell origin of the immortal Col-GFP HSC line.
Int J Mol Sci 2025, 26:7764. 		5.600 TCG
916 M Hospodářská, P Mora, AC Voleníková, A Al-Rikabi, M Altmanová, SA Simanovsky, N Tolar, T Pavlica, K Janečková, J Štundlová, K Bobryshava, M Jankásek, M Hiřman, T Liehr, M Reichard, EY Krysanov, P Ráb, C Englert, P Nguyen, A Sember.
Multiple origins of sex chromosomes in Nothobranchius killifishes.
Mol Ecol 2025, 34:e70029. 		3.700 EVO
915 M Rincic, L Brecevic, T Liehr, K Gotovac Jercic, I Doder, F Borovecki.
Customized chromosomal microarrays for neurodevelopmental disorders.
Genes 2025, 16:868. 		3.100 sSMC/ CG
914 MN Correia, S Kankel, IM Carreira, JB Melo, T Liehr.
New insights into chromosomal regions 15p11.2 to 15q11.2 by studying submicroscopic variations using molecular cytogenetics.
Cytogenet Genome Res 2025, 165:57–69. 		2.000 sSMC/ CG
913 S Kaewdaungdee, ZW Sham HX Ho, SY Lee, T Tanee, YD Benoit, T Liehr, S Daduang, R Sudmoon, A Chaveerach.
Barleria extracts containing barlerin and verbascoside boost immunity and regulate CYP450 gene in prostate cancer.
Sci Rep 2025, 15: 21942. 		4.900 other
912 T Liehr, S Singer, U Mau-Holzmann, E Daumiller, U Kornak.
Results of chromosomal microarray need to always be checked by (molecular) cytogenetics
—even if they seem to be simple deletions.
Genes 2025, 16:714.
 		3.100 CG
911 T Liehr, P Li.
A new database on constitutional human ring chromosomes.
OBM Genetics. 2025, 9:298. 		n.a. CG
910 Liehr, E Cross, S Kankel.
Directional genomic hybridization (dGH™) identifies small, inverted duplications in situ.
Front Genet 2025, 16:1604822. 		3.000 CG
909 MPB de Oliveira, GA Deon, FdMC Sassi, FH Santos de Souza, CA Gomes Goes, R Utsunomia, F Porto-Foresti, JA Dziechciarz Vidal, AB da Silva, T Ezaz, T Liehr, MdBCioffi.
Repeatome dynamics and sex chromosome differentiation in the XY and XY1Y2 systems of the fish Hoplias malabaricus (Teleostei; Characiformes).
Int J Mol Sci 2025, 26:6039. 		5.600 EVO
908 T Liehr, N Padutsch, S Kankel.
Hapten-labeled DNA probes can be stored and used in fluorescence in situ hybridization for decades. Front Genet 2025, 16:1569308. 		3.000 M
907 Y Wang, T Liehr.
The need for a concert of cytogenomic methods in chromosomic research and diagnostics.
Genes 2025, 16:533. 		3.100 M
906 PG Setti, T Ezaz, GA Deon, R Utsunomia, A Tanomtong, S Ditcharoen, N Donbundit, M Sumontha, K Seetapan, P Buasriyot, K Pinthong, W Thongnetr, N dos Santos, F Porto-Foresti, T Liehr, MdB Cioffi.
Evolution of ZW sex chromosomes in ptyas snakes (Reptilia, Colubridae): New insights from a molecular cytogenetic perspective.
IJMS 2025; 26:4540. 		5.600 EVO
905 A Weise, AA Ornellas, G Alves, C Pentzold, J Holler, M Wolter, E Jamali, B Theis, T Liehr.
Satellite-DNA amplification in advanced prostate cancer is largely independent from euchromatic and oncogene amplicons.
J Histochem Cytochem 2025, 73:109-113. 		1.500 TCG
904 P Buasriyot, W Supiwong, N Muanglen, N Donbundit, S Ditcharoen, P Chumpol, P Saenjundaeng, S Tongnunui, S Arunsang, W Thongnetr, S Juntharat, K Seetapan, T Liehr, MB Cioffi, P Rab, A Tanomtong.
 Microsatellite repeat mapping shows inner chromosomal diversification in highly conserved karyotypes of Asian cyprinid fishes.
Comp Cytogenet 2025, 19:29-50. 		0.900 EVO
903 FMC Sassi, RZ dos Santos, T Ezaz, MA Garrido-Ramos, R Utsunomia, GA Deon, F Porto-Foresti, T Liehr, MB Cioffi.
Independent evolution of satellite DNA sequences in homologous sex chromosomes of Neotropical armored catfish (Harttia).
Communic Biol 2025, 8:524. 		5.900 EVO
902 T Liehr, S Kankel, KS Hardt, EM Buhl, H Noels, DT Keller, SK Schröder-Lange, Ralf Weiskirchen.
Genetic and molecular characterization of H9c2 rat myoblast cell line.
Cells 2025, 14:502. 		5.900 TCG
901 AM de Oliveira, GA Deon, A Sember, CA Gomes Goes, W Supiwong, A Tanomtong, F Porto-Foresti, R Utsunomia, T Liehr, MdB Cioffi.
Repetitive DNAs and differentiation of the ZZ/ZW sex chromosome system in the combtail fish Belontia hasselti (Perciformes: Osphronemidae).
BMC Ecol Evol 2025, 25:25. 		2.700 EVO
900 GM Souza, JAD Vidal, R Utsunomia, GA Deon, EHC de Oliveira, RT Franca, F Porto-Foresti, T Liehr, FHS de Souza, R Kretschmer, MB Cioffi.
Cytogenomic analysis in Seriemas (Cariamidae): Insights into an atypical avian karyotype.
J Hered 2025, 116:441-452. 		2.200 EVO
899 JAD Vidal, D Charlesworth, R Utsunomia, MA Garrido-Ramos, RZ Dos Santos, F Porto-Foresti, RF Artoni, T Liehr, MC de Almeida, M de Bello Cioffi.
Unraveling the role of satellite DNAs in the evolution of the giant XY sex chromosomes of the flea beetle Omophoita octoguttata (Coleoptera, Chrysomelidae).
BMC Biol 2025, 23:53. 		5.400 EVO
898 R Sudmoon, T Tanee, W Wonok, U Ameamsri, T Liehr, S Daduang, P Siripiyasing, A Chaveerach.
Discovery of rhynchophylline and mitraphylline in two Thai Mitragyna species and the investigation of their biological activity via opioid gene expression analysis.
Sci Rep 2025, 15:5865. 		4.900 other
897 F Sheth, J Shah, T Liehr, M Desai, H Patel, J Sheth, H Sheth.
Complex chromosomal rearrangements in female carriers experiencing recurrent pregnancy loss or poor obstetric history and literature review.
J Assist Reprod Genet 2025, 42:39-62. 		2.800 CG
896 T Liehr, M Rincic.
Cytogenomic characterization of murine cell line Sarcoma 180 = S-180.
IJMS 2025, 26:1127. 		5.600 TCG
895 H Bouchahta, Z El Amrani, SC Elalaoui, F Ouboukss, A Sbiti, L Sbabou, T Liehr, A Sefiani, A Natiq.
Maternally derived complex small supernumerary marker chromosome 22 associated with cat-eye syndrome like features.
OBM Genetics 2025, 9: doi:10.21926/obm.genet.2501282. 		n.a. sSMC
894 T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2025, 55:22. 		n.a. sSMC
893 BM Hussen, SR Abdullah, RM Jaafar, MF Rasul, R Aroutiounian, T Harutyunyan, T Liehr, M Samsami, M Taheri.
Circular RNAs as key regulators in cancer hallmarks: New progress and therapeutic opportunities. Crit Rev Oncol Hematol 2025, 2:104612. 		6.200 TCG
55% of publications of Institute of Human Genetics Jena in the actual year

2024
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
892
T Liehr, S Kankel, EM Buhl, SK Schröder-Lange, R Weiskirchen.
Genetic characteristics of the rat fibroblast cell line Rat-1
Cells 2024, 14:21.
 5.200 TCG
891
T Liehr.
Kleine überzählige Markerchromosomen
Leaflet published 2017, rev. in 2018 and 2024 by UNIQUE, Rare Chromosome Disorder Support Group
n.a. sSMC
890
J Butt. translated to German by V Mulhall and T Liehr.
Nach der Diagnose: Was nun? (Ausgabe für Menschen außerhalb Großbritanniens)
Leaflet published originally in 20 24 by UNIQUE, Rare Chromosome Disorder Support Group
n.a. CG
889
M Silva JP Castro, AI Makunin, FF Barby, EHC de Oliveira, T Liehr, MB Cioffi, F Porto-Foresti, F Foresti, RF Artoni.
Investigation of Astyanax mexicanus (Characiformes, Characidae) chromosome 1 structure reveals unmapped sequences and suggests conserved evolution.
PLoS One 2024, 19:e0313896.
 2.600 EVO
888
L Hergenhahn, N Padutsch, S Azawi, R Weiskirchen, T Liehr, Martina Rinčic.
Cytogenomic characterization of murine neuroblastoma cell line Neuro-2a and its two derivatives Neuro-2a TR-alpha and Neuro-2a TR-beta.
Cells 2024, 13:1889.
 5.200 TCG
887
J Moch, M Radtke, T Liehr, T Eggermann, C Gilissen, R Pfundt, G Astuti, J Hentschel, I Schumann.
Automatized detection of uniparental disomies in a large cohort.
Hum Genet 2024, 142: 955-964.
 3.600 CG
886 15.700 INT
885
T Liehr.
Noninvasive prenatal testing (NIPT) results are less accurate the later applied during pregnancy.
Taiw J Obstet Gynecol 2024, 63:892-895.
 2.200 CG
884
S Pires, P Jorge, T Liehr, N Oliva-Teles.
The challenge of classifying human chromosomal heteromorphisms by banding cytogenetics: from the controversial guidelines to the need of a universal scoring system.
Hum Genome Var 2024, 11:38.
 1300 CG
883
M Bertrand, G Shah, BS Pedersen, A Schulz, A Weise, T Liehr, P Huppke, S DiTroia, AR Quinlan, TB Haack, RA Husain.
De novo AHDC1 deletions identified by genome sequencing in two individuals with Xia-Gibbs syndrome.
Mol Syndromol 2024, 15:389-397.
 0.900 CG
882
J Seixas, N Padutsch, S Kankel, T Liehr, A Sy.
Molecular cytogenetic characterization of rare, but repeatedly observed inversions in German population.
Cytogenet Genome Res 2024, 164:78-84.
 1.300 CG
881
A Llamos-Paneque, I Echevarria-Frutos, A León-Siosa, T Herrmann, T Liehr.
Becker phenotype muscular dystrophy in a man with Klinefelter syndrome: a rare association.
OBM-Genetics 2024, 8: 262.
 n.a. CG
880
T Harutyunyan, A Sargsyan, L Kalashyan, N Stepanyan, R Aroutiounian, T Liehr, G Hovhannisyan.
DNA damage in moderate and severe COVID-19 cases: Relation to demographic, clinical, and laboratory parameters.
IJMS 2024, 25:10293.
 4.900 CG
879
A Makowska, U Kontny, T Liehr, R Weiskirchen.
The struggle continues: Cell misidentification.
Lab Investig 2024, 104:102124.
 4.200 TCG
878
GM Souza, R Kretschmer, GA Toma, AM de Oliveira, GA Deon, PG Setti, R Zeni Dos Santos, CAG Goes, A Del Valle Garnero, RJ Gunski, EHC de Oliveira, F Porto-Foresti, T Liehr, R Utsunomia, M de Bello Cioffi.
Satellitome analysis on the pale-breasted thrush Turdus leucomelas (Passeriformes; Turdidae) uncovers the putative co-evolution of sex chromosomes and satellite DNAs.
Sci Rep 2024, 14:20656.
 3.900 EVO
877
GA Toma, A Sember, CAG Goes, R Kretschmer, F Porto‑Foresti, LAC Bertollo, T Liehr, R Utsunomia, MdB Cioffi.
Satellite DNAs and the evolution of the multiple X1X2Y sex chromosomes in the wolf fish Hoplias malabaricus (Teleostei; Characiformes).
Sci Rep 2024; 14:20402.
 3.900 EVO
876
L Afif, Z El Amrani, A Sbiti, I Ratbi, IC Jaouad, Y El Kadiri, T Liehr, A Sefiani, A Natiq.
First female patient with de novo 6q22.31q27 duplication and Xq28 deletion: case report and brief literature review.
OBM Genetics 2024, 8:259.
 n.a. CG
875
P Buasriyot, FMC Sassi, N Donbundit, W Supiwong, S Kaewsri, S Jumrusthanasan, C Suwannapoom, K Pinthong, A Tanomtong, K Yanukun, N Tantisuwichwong, N Muanglen, T Liehr, MB Cioffi.
Comparative karyotypic study of fifteen cyprinids (Cyprinidae, Cyprininae) species. An insight into the chromosomal evolution of the tribe Systomini.
PLoS One 2024, 19:e0305828
2.600 EVO
874 T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2024, 54:15.
 n.a. sSMC
873
T Harutyunyan, A Sargsyan, L Kalashyan, H Igityan, B Grigoryan, H Davtyan, R Aroutiounian, T Liehr, G Hovhannisyan.
Changes in telomere length in leukocytes and leukemic cells after ultrashort electron beam radiation. IJMS 2024, 25:6709.
4.900 TCG
872
V Graiqevci-Uka, E Behluli, R Hadziselimovic, T Liehr, G Temaj.
Implementation of pharmacogenetics for treatment of patients with acute lymphoblastic leukemia.
 Res Results Pharmacol 2024, 10:27-39
n.a. TCG
871
ALT Fontes, N Padutsch, S Kankel, T Liehr.
Molecular cytogenetic characterization of rare, but repeatedly observed translocations.
OBM Genetics 2024, 8:240.
n.a. CG
870
R Weiskirchen, S Kankel, T Liehr.
Short tandem repeat profile for authentication of immortal murine cancer cell line MH-22A.
Cell Tissue Biol, 2024, 18:273-279.
n.a. TCG
869
PA Nikitin, S Sidorov, T Liehr, K Klimina, A Al-Rikabi, V Korchagin, O Kolomiets, M Arakelyan, V Spangenberg.
Variants of a major DNA satellite discriminate parental subgenomes in a hybrid parthenogenetic lizard Darevskia unisexualis (Darevsky, 1966).
J Exp Zool B Mol Dev Evol 2024, 342:368-379.
1.700 EVO
868
C Keramida, I Papoulidis, E Pappa, T Liehr, K Kalmantis, A Gerede, E Pavlidou, MB Petersen, E Manolakis.
An asymptomatic male individual carrying a 5.72 Mb de novo deletion in 8p23.2‑p23.3: A case report.
 Exp Therap Med 2024, 27:241.
2.400 CG
867
Z el Amrani, A Natiq, A Sbiti, I Ratbi, T Liehr, A Sefiani, M Sahli.
Currarino syndrome in two Moroccan siblings with inherited 7q36 deletion due to maternal t(7;21)(q36;p11)mat: a case report.
Mol Syndromol 2024, 15:125-129.
0.900 CG
866 2.600 EVO
865
T Liehr.
Editorial: Co-occurrence of numerical and structural aberration—small supernumerary marker chromosomes and B-chromosomes.
Front Genet 2024, 14:1408674.
2.800 sSMC
864
P Hyckel, T Liehr.
Thoughts on the etiology of cherubism.
J Clin Med 2024, 13:2082.
2.900 CG
863 n.a. EVO
862
NA Ariffen, AA Ornellas, G Alves, AM Shana'ah, S Sharma, S Kankel, E Jamali, B Theis, T Liehr.
Amplification of different satellite-DNAs in prostate cancer.
Pathol Res Pract 2024, 256:155269.
3.200 TCG
861
D Montjean, M Beaumont, A Natiq, N Louanjli, A Hazout, P Miron, T Liehr, R Cabry, I Ratbi, M Benkhalifa.
Genome and epigenome disorders and male infertility: Feedback from 15 years of clinical and research experience.
Genes 2024, 15:377.
2.800 CG
860
WF Molina, S Khensuwan, RLR de Moraes, FdMC Sassi, GWWF da Costa, DZ Miguel, W Supiwong, S Jantarat, K Phintong, K Seetapan, S Ditcharoen, A Tanomtong, T Liehr, MdB Cioffi.
Karyotypic stasis and its implications for extensive hybridization events in corallivores species of butterflyfishes (Chaetodontidae).
Heliyon 2024, 10:e27435.
3.600 EVO
859
G Jedraszak, F Jobic, A Receveur, F Bilan, B Gilbert-Dussardier, B Tiffany, C Missirian, M Willems, S Odent, J Lucas, C Dubourg, E Schaefer, S Scheidecker, J Lespinasse, A Goldenberg, A Guerrot,  G Joly-Helas, P Chambon, C Le Caignec, A David, C Coutton, V Satre, G Vieville, F Amblard, R Harbuz, D Sanlaville, M Till, C Vincent-Delorme, C Colson, J Andrieux, S Naudion, J Toutain, C Rooryck, B de Fréminville, F Prieur, V Cormier Daire, D Amram, P Kleinfinger, MB Schulze, G Raabe-Meyer, C Courage, J Lemke, EG Stefanou, T Loretta, M Emmanouil, S Kitsiou Tzeli, H Sodowska, J Anderson, A Nandini, H Copin, L Garçon, T Liehr, G Morin.
Cat eye syndrome: Clinical, cytogenetics and familial findingsin a large cohort of 43 patients highlighting the importance of congenital heart disease and inherited cases.
Am J Med Genet A 2024, 194:e63476.
1.700 sSMC
858
VC Sales‑Oliveira, RZ dos Santos, CAG Goes, RM Calegari, MA Garrido‑Ramos, M Altmanová, T Ezaz, T Liehr, F Porto‑Foresti, R Utsunomia, MB Cioffi.
Evolution of ancient satellite DNAs in extantalligators and caimans (Crocodylia, Reptilia).
BMC Biology 2024, 22:47.
4.500 EVO
877 T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2024, 53:12-13.
 n.a. sSMC
856
F Ouboukss, Z El Amrani, H Bouchahta, I Ratbi, A Sbiti, T Liehr, A Sefiani, A Natiq.
A maternally derived complex small supernumerary marker chromosome involving chromosomes 8 and 14: case report and review of the literature.
Front Genet 2024, 15:1331676.
2.800 sSMC
855
R Kretschmer, GA Toma, GA Deon, N dos Santos, RZ dos Santos, R Utsunomia, F Porto-Foresti, RJ Gunski, A Del Valle Garnero, T Liehr, EHC de Oliveira, TR Ochotorena de Freitas, M de Bello Cioffi.
Satellitome analysis in the southern lapwing (Vanellus chilensis) genome: Implications for SatDNA evolution in charadriiform birds.
Genes 2024, 15:258.
2.800 EVO
854 15.700 CG
853
S Khensuwan, F de Menezes Cavalcante Sassi, RLR de Moraes, P Rab, T Liehr, W Supiwong, K Seetapan, A Tanomtong, N Tantisuwichwong, S Arunsang, P Buasriyot, S Tongnunui, MB Cioffi.
Chromosomes of Asian cyprinid fishes: Novel insight into the chromosomal evolution of Labeoninae (Teleostei, Cyprinidae).
PLoS One 2024, 19:e0292689.
2.600 EVO
852
J Gharesouran, H Hosseinzadeh, R Ghergherechi, S Shiva, M Taheri, T Liehr, M Rezazadeh.
Loss of helicase C-terminal domain of SMARCAL1 protein associated with severe Schimke immuno-osseous dysplasia.
Pathol Res Pract 2024, 254:155092.
3.200 CG
46% of publications of Institute of Human Genetics Jena in the actual year

2023
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
851
V Sales‑Oliveira, M Altmanova, V Gvozdik, R Kretschmer, T Ezaz, T Liehr, N Padutsch, G Badjedjea, R Utsunomia, A Tanomtong, M Cioffi.
Cross-species chromosome painting and repetitive DNA mapping illuminate the karyotype evolution in true crocodiles (Crocodylidae).
Chromosoma 2023, 132:289-303.
2.500 EVO
850
D Dedukh, A Maslova, A Al-Rikabi, N Padutsch, T Liehr, A Krasikova.
Karyotypes of water frogs from the Pelophylax esculentus complex: results of cross-species chromosomal painting.
Chromosoma 2023, 132:329-342.
2.500 EVO
849
T Liehr, M Ziegler, L Person, S Kankel, N Padutsch, A Weise, JP Weimer, H Williams, S Ferreira, JB Melo, IM Carreira.
Small supernumerary marker chromosomes derived from human chromosome 11.
Front Genet 2023, 14:1293652.
2.800 sSMC
848
E Angelopoulou, A Theodosiou, I Papaevripidou, A Alexandrou, T Liehr, Y Gyftodimou, EG Stefanou, C Sismani.
CHD2 pathogenic nonsense variant in a three-generation family with variable phenotype and a paracentric inversion 16: Case report.
Heliyon 2023, 9:e22987.
3.400 CG
847
T Liehr.
Perspective: Is there any reason to stay in human genetic societies as cytogeneticists?
Qeios 2023, VY79EZ.
n.a. other
846
F dMC Sassi, A Sember, GA Deon, T Liehr, N Padutsch, OT Oyakawa, MR Vicari, LAC Bertollo, O Moreira‑Filho, MdB Cioffi.
Homeology of sex chromosomes in Amazonian Harttia armored catfishes supports the X‑fission hypothesis for the X1X2Y sex chromosome system origin.
Sci Reports 2023, 13:15756.
 4.600 EVO
845
T Liehr.
Any reason to stay in human genetic societies as cytogeneticists?
LinkedIn
 n.a. other
844
E Behluli, T Liehr, R Hadziselimovic, G Temaj.
Epigenetics and treatment of systemic lupus erythematosus.
Pharmacia 2023, 70:1005-1013.
 1.100 CG
843
RLR de Moraes, FdMC Sassi, JAD Vidal ,CAG Goes, RZ dos Santos, JHF Stornioli, F Porto-Foresti, T Liehr, R Utsunomia, MdB Cioffi.
Chromosomal rearrangements and satellite DNAs: Extensive chromosome reshuffling and the evolution of neo-sex chromosomes in the genus Pyrrhulina (Teleostei; Characiformes).
Int J Mol Sci 2023, 24:13654.
 4.900 EVO
842
G Hovhannisyan, T Harutyunyan, R Aroutiounian, T Liehr.
The diagnostic, prognostic and therapeutic potential of cell-free DNA with a special focus on COVID-19 and other viral infections.
Int J Mol Sci 2023, 24:14163.
 4.900 CG
841
 S Khensuwan, W Supiwong, C Suwannapoom, P Buasriyot, S Jantarat, W Thongnetr, N Muanglen, P Kaewmad, P Saenjundaeng, K Seetapan, T Liehr, A Tanomtong.
A comparative cytogenetic study of Hypsibarbus malcolmi and H. wetmorei (Cyprinidae: Tribe Poropuntiini).
Comp Cytogenet 2023, 17:181-194.
 1.000 EVO
840
PS Ambulkar, T Liehr, M Jain, J Waghmare, N Gangane, P Narang, AK Pal.
Molecular characterization of de novo ring chromosome 21 in a child with seizures, growth retardation, and multiple congenital anomalies.
J Genet 2023, 102:44.
 1.400 CG
839
MP Barcellos de Oliveira, R Kretschmer, GA Deon, GA Toma, T Ezaz, CA Gomes Goes, F Porto-Foresti, T Liehr, R Utsunomia, MdB Cioffi.
 Following the pathway of W chromosome differentiation in Triportheus (Teleostei: Characiformes).
Biology 2023, 12:1114.
 3.600 EVO
838
FdMC Sassi, GA Deon, A Sember, T Liehr, OT Oyakawa, O Moreira-Filho, LAC Bertollo, MR Vicari, MdB Cioffi.
Turnover of multiple sex chromosomes in Harttia catfish (Siluriformes, Loricariidae): a glimpse from whole chromosome painting.
Front Genet 2023, 14:1226222.
 2.800 EVO
837
E Jamali, A Safarzadeh, BM Hussen, T Liehr, S Ghafouri-Fard, M Taheri.
Single cell RNA-seq analysis with a systems biology approach to recognize important differentially expressed genes in pancreatic ductal adenocarcinoma compared to adjacent non-cancerous samples by targeting pancreatic endothelial cells.
Pathol Res Pract 2023, 248:154614.
 2.900 TCG
836
L Spahiu, JA Sayera, E Behluli, T Liehr, G Temaj.
Identification of likely recurrent CEP290 mutation in a child with Joubert syndrome and cerebello-retinal-renal features.
F1000Res 2023, 11:388.
 n.a. CG
835
GA Toma, N Dos Santos, RZ Dos Santos, P Rab, R Kretschmer, T Ezaz, LAC Bertollo, T Liehr, F Porto-Foresti, T Hatanaka, A Tanomtong, R Utsunomia, MB Cioffi.
Cytogenetics meets genomics: Cytotaxonomy and genomic relationships among color variants of the Asian arowana Scleropages formosus.
Int J Mol Sci 2023, 24:9005.
 4.900 EVO
834
EH Steffensen, A Skakkebæk, K Gadsbøll, OB Petersen, T Westover, H Strange, The NIPT-SCA-map Study Group (including among many other T Liehr), I Vogel.
Inclusion of sex chromosomes in noninvasive prenatal testing in Asia, Australia, Europe and the USA: A survey study.
Prenat Diagn 2023, 43:144-155.
 2.700 CG
833
JAD Vidal, FdeMC Sassi, RLR de Moraes, RF Artoni, T Liehr, MB Cioffi, MC de Almeida.
Giant sex chromosomes in omophoita species (Coleoptera, Chrysomelidae): Structural and evolutionary relationships revealed by Zoo-FISH and comparative genomic hybridization (CGH).
Insects 2023, 14:440.
2.700 EVO
832
S Khensuwan, FdMC Sassi, RLR Moraes, S Jantarat, K Seetapan, K Phintong, W Thongnetr, S Kaewsri, S Jumrusthanasan , W Supiwong, P Rab, A Tanomtong, T Liehr, MB Cioffi.
Chromosomes of Asian cyprinid fishes: Genomic differences in conserved karyotypes of ‘Poropuntiinae’ (Teleostei, Cyprinidae).
Animals 2023, 13:1415.
2.700 EVO
831
B Mingkwan, FdMC Sassi, N Muanglenm, S Pinmongkhonkul, K Pinthong, S Tongnunui, P Yeesin, A Tanomtong, T Liehr, MdB Cioffi, W Supiwong.
Evolutionary tracks of chromosomal diversification in Trichopsis (Anabantiformes, Osphronemidae) fishes: New insights from a molecular cytogenetic perspective.
Biodiversitas 2023, 24:1551-1559.
n.a. EVO
830
D Heydeck, C Ufer, KR Kakularam, M Rothe, T Liehr, P Poulain, H Kuhn.
Functional characterization of transgenic mice overexpressing human 15-lipoxygenase-1 (ALOX15) under the control of the aP2 promoter.
Int J Mol Sci 2023, 24:4815.
4.900 CG
829
V Graiqevci-Uka, E Behluli, L Spahiu, T Liehr, G Temaj.
A new case of childhood acute lymphoblastic B-cell leukemia from Pristina.
Acta Med Bulg 2023, 50:59-62.
n.a. TCG
828
L Spahiu, E Behluli, V Graiqevci-Uka, T Liehr, G Temaj.
Joubert syndrome: molecular basis and treatment.
J Mother Child / Medycyna Wieku Rozwojowego 2023, 26:118-123.
n.a. CG
827
L Spahiu, E Behluli, R Hadziselimovic, T Liehr, G Temaj.
Mucopolysaccharidosis type III (subtype IIIB) diagnosis as a spectrum disorder: A case report from Kosovo.
Fol Med 2023, 65:161-165.
n.a. CG
826
V Graiqevci-Uka, E Behluli, L Spahiu, T Liehr, G Temaj.
Targeted treatment and immunotherapy in high-risk and relapsed/ refractory pediatric acute lymphoblastic leukemia.
Curr Ped Rev 2023, 19:150-156.
1.300 TCG
25% of publications of Institute of Human Genetics Jena in the actual year
 

 2022
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
825
S Azawi, F Kramer, T Liehr, M Rincic.
First cytogenomic characterization of murine cutaneous sarcoma cell line TSC2ang1.
Science Technology and Engineering Journal (STEJ) 2022, 8:1-16.
n.a. TCG
824
G Loof, D Szabo, V Garg, A Kukalev, LZ Redondo, R Kempfer, TM Sparks, Y Zhang, CJ Thieme, S Carvalho, A Weise, M Balachandran, T Liehr, LR Welch, A-K Hadjantonakis, A Pombo.
3D genome topologies distinguish pluripotent epiblast and primitive endoderm cells in the blastocyst.
bioRxiv 2022, 10.19.512781.
n.a. INT
823
E Behluli, N Nuhii, T Liehr, G Temaj.
Suspicions regarding the genetic inheritance of acute lymphoblastic leukemia in patients with Down syndrome.
J Mother Child / Medycyna Wieku Rozwojowego 2022, 26:104-110
n.a. TCG
822
S Azawi, S Kankel, T Liehr, M Rincic.
First cytogenomic characterization of murine testis tumor cell line MLTC-1.
MEBM 2022, 4:10-14.
n.a. TCG
821
T Liehr, T Harutyunyan, H Williams, A Weise.
Restrictions and advantages of non-invasive prenatal testing (NIPT).
Encylopedia, 2022, 38834.
 n.a. CG
820
Y Khalifa, HY Hassan, A Weise, T Liehr, H Alkhayyat.
Molecular cytogenetic and phenotypic characterization of Phelan McDermid and 22q13 duplication syndrome: a case report.
Mol Cytogenet 2022, 15:52.
1.300 CG
819
LA Méndez-Rosado, N de León-Ojeda, A García, F Sheth, A Gaadi, AA Bousfiha, M Lehlimi, A Natiq, OS Kurinnaia, SG Vorsanova, I Iourov, D Huhle, T Liehr.
Clinical characterization of 72 patients with del(22)(q11.2q11.2) from different ethnic background.
Egypt J Med Hum Genet 2022, 23:158.
1.300 CG
818
T Liehr.
Was man zu Grenzen und Möglichkeiten des Noninvasive prenatal testing (NIPT) unbedingt wissen sollte.
pädiatrische praxis 2022, 99:7-14.
n.a. CG
817
L Spahiu, E Behluli, R Hadziselimovic, T Liehr, G Temaj.
Pathogenesis and therapy in polycystic kidney disease.
Acta Medica Mediter 2022, 38:3001-3009.
0.300
 		CG
816
V Graiqevci-Uka, E Behluli, LSpahiu, T Liehr, G Temaj.
Targeted treatment and immunotherapy in high-risk and relapsed/ refractory pediatric acute lymphoblastic leukemia.
Curr Ped Rev 2023, 19:150-156.
n.a.
 		TCG
815
Y Wang, KR Kumar, T Liehr.
Molecular combing and its application in clinical settings.
Mol Cytogenet 2022, 15:50.
1.300
 		CG
814
T Liehr, T Harutyunyan, H Williams, A Weise.
Non-invasive prenatal testing in Germany.
Diagnostics 2022, 12:2816.
3.600
 		CG
813
P Mohanty, D Shetty, T Liehr, K Mrasek, N Khattry.
Intrachromosomal amplification of BCR expressed as homogenously staining region (hsr) in a case of acute myeloid leukemia with myelodysplasia-related changes.
Int J Lab Hematol 2022, 44:993-994.
3.000
 		TCG
812
G Alves, MH Ornellas, T Liehr.
The role of Calmodulin Binding Transcription Activator 1 (CAMTA1) gene and its putative genetic partners in the human nervous system.
Psychogeriatrics 2022, 22:869-878.
2.000
 		CG
811
S Classen, E Rahlf, J Jungwirth, N Albers, LP Hebestreit, A Zielinski, L Poole, M Groth, P Koch,
T Liehr, S Kankel, N Cordes, C Petersen, K Rothkamm, H Pospiech, K Borgmann.
Partial reduction in BRCA1 gene dose modulates DNA replication stress level and thereby contributes to sensitivity or resistance.
Int J Mol Sci 2022, 23:13363.
5.600
 		TCG
810
T Liehr.
Chromosomal heteromorphisms and cancer susceptibility revisited.
Cells 2022, 11:3239.
6.000
 		TCG
809
Z El Amrani, SC Elalaoui, W Jdioui, A Sbiti, I Ratbi, T Liehr, A Sefiani, A Natiq.
Complex translocation leading to13q interstitial deletion in a Moroccan child with retinoblastoma and intellectual disability.
Ophthalmic Genetics 2022; 43:689-692.
1.200
 		CG
TCG
808
P Li, B Dupont, Q Hu, M Crimi, Y Shen, I Lebedev, T Liehr.
The past, present, and future for constitutional ring chromosomes: A report of the International Consortium for Human Ring Chromosomes (ICHRC).
HGG Adv 2022, 3:100139.
4.400
 		CG
807
V Nilius-Eliliwi, M Tembrink, WM Gerding, KP Lubieniecki, JM Lubieniecka, S Kankel, T Liehr, T Mika, F Dimopoulos, K Döhner, R Schroers, HHP Nguyen, DB Vangala.
Broad genomic workup including optical genome mapping uncovers a DDX3X::MLLT10 gene fusion in acute myeloid leukemia.
Front Oncol 2022, 12:959243
4.700
 		TCG
806 5.200
 		CG
805
T Liehr.
False-positives and false-negatives in non-invasive prenatal testing (NIPT): what can we learn from a meta-analyses on > 750,000 tests?
Mol Cytogenet 2022, 15:36.
1.300
 		CG
804
TD de Oliveira, NA Bertocchi, R Kretschmer, EHC de Oliveira, MB de Cioffi, T Liehr, TR Ochotorena de Freitas.
Genomic organization of microsatellites and LINE-1-like  etrotransposons: evolutionary implications for Ctenomys minutus (Rodentia: Ctenomyidae) cytotypes.
Animals 2022, 12:2091.
3.000
 		EVO
803
T Harutyunyan, T Liehr.
Can age related mosaic loss of Y chromosome really cause cardiac damage in men?
eletter (1) for Sano, et al.
Science 2022, 377:292-297.
n.a.
(as just a comment)
 		CG
802
V Barbaro, A Orvieto, G Alvisi, M Bertolin, F Bonelli, T Liehr, T Harutyunyan, S Kankel, G Joksic, S Ferrari, E Daniele, D Ponzin, D Bettio, L Salviati, E Di Iorio.
Analysis and pharmacological modulation of senescence in human epithelial stem cells.
J Cell Mol Med 2022, 26:3977-3994.
5.300 CG
801
S Azawi, L-M Barf, T Liehr, S Kankel, M Rincic.
First cytogenomic characterization of murine testicular tumor cell line I-10.
OBM Genetics 2022, 6:159.
 n.a. TCG
800
M Paneque, T Liehr, C Serra-Juhe, U Moog, B Melegh, I Carreira.
The need for recognition of core professional groups in genetics healthcare services in Europe.
Europ J Hum Genet 2022; 30:639-640.
5.200 other
799
GA Deon, L Glugoski, T Hatanaka, FdMC Sassi, V Nogaroto, LAC Bertollo, T Liehr, A Al-Rikabi, O Moreira-Filho, MdB Cioffi, MR Vicari.
Evolutionary breakpoint regions and chromosomal remodeling in Harttia (Siluriformes: Loricariidae) species diversification.
Genet Mol Biol 2022, 45:e20210170.
 2.100 EVO
798
T Liehr.
Was man zu Grenzen und Möglichkeiten des Noninvasive prenatal testing (NIPT) unbedingt wissen sollte.
gynäkologische praxis 2022, 49:425-432.
n.a. CG
797
N Baba, A Lengyel, E Pinti, E Yapici, I Schreyer, T Liehr, G Fekete, T Eggermann.
Microdeletions in 1q21 and 8q12.1 depict two additional molecular subgroups of Silver-Russell syndrome like phenotypes.
Mol Cytogenet 2022, 15:19.
1.300 UPD
796
A Weber, T Liehr, A Al-Rikabi, S Bilgen, U Heinrich, J Schiller, M Stumm.
The first neocentric, discontinous, and complex small supernumerary marker chromosome composed of 7 euchromatic blocks derived from 5 different chromosomes.
Biomedicines 2022, 10:1102.
4.700 sSMC
795
M Paneque, C Serra Juhé, B Melegh, I Carreira, U Moog, T Liehr.
Über die Notwendigkeit der Anerkennung von sog. Kernberufsgruppen innerhalb der genetischen Gesundheitsversorgung in Europa.
Med Gen 2022, 34:81-83, correction under 34:189-191.
1.100 other
794
PHN Ferreira, FHS de Souza, RLR de Moraes, M Perez, F de MC Sassi, PF Viana, E Feldberg, T Ezaz, T Liehr, LAC Bertollo, M de B Cioffi.
The genetic differentiation of Pyrrhulina (Teleostei, Characiformes) species is likely influenced by both geographical distribution and chromosomal rearrangements.
Front Genet 2022, 13:869073.
3.700 EVO
793
W Kasiroek, S Phimphan, K Pinthong, C Suwannapoom, S Aiumsumang, T Liehr, W Supiwong, A Tanomtong.
Comparative cytogenomic analysis of cardinalfishes (Perciformes, Apogonidae) from Thailand.
The Nucleus 2022, 65:57-66.
4.700 EVO
792
RRC de Matos, GM Ferreira, C Meyer, R Marschalek, P Larghero, RC Ribeiro, T Liehr, M Othman, MTdeSM Bizarro, E Sobral da Costa, MGP Land, E Abdelhay, R Binato, MLM Silva.
KMT2A-MLLT1 and the novel SEC16A-KMT2A in a cryptic three-way translocation t(9;11;19) present in an infant with acute lymphoblastic leukemia.
J Pediatr Hematol Oncol 2022, 44:e719.
1.200 TCG
791
GA Deon, L Glugoski, FdMC Sassi, T Hatanaka, V Nogaroto, LAC Bertollo, T Liehr, A Al-Rikabi, OdB Moreira-Filho, MdB Cioffi, MR Vicari.
Chromosomal rearrangements and origin of the multiple XX/XY1Y2 sex chromosome system in Harttia species (Siluriformes: Loricariidae).
Front Genet 2022, 13:877522.
3.700 EVO
790
X Fan, K Pinthong, EHC de Oliveira, A Tanomtong, H Chen, A Weise, T Liehr.
First comprehensive characterization of Phayre’s leaf-monkey (Trachypithecus phayrei) karyotype.
Front Genet 2022, 13:841681.
 3.700 EVO
789
T Liehr, A Weise, L Person, N Padutsch, S Kankel.
How to obtain high quality metaphase spreads for molecular cytogenetics.
Current Protocols 2022, 2:e392.
n.a. M
788
T Liehr.
Uniparental disomy is a chromosomic disorder in the first place.
Mol Cytogenet 2022, 15:5. 
1.300 UPD
787
FHS de Souza, FdMC Sassi, PHN Ferreira, LAC Bertollo, T Ezaz, T Liehr, MF Perez, MB Cioffi.
Integrating cytogenetics and population genomics: Allopatry and neo-sex chromosomes shaped the genetic divergence in the Erythrinus erythrinus species complex (Teleostei, Characiformes).
Biology 2022, 11:315.
 4.200 EVO
786
A Wafa, B Ali, F Moassass, M Kheder, A Aljapawe, B AL-Halabi, K Mrasek, T Liehr, W Al-Achkar.
Acute myeloid leukemia due to germline CEBPA mutation in a Syrian family.
Mol Genet Genomic Med 2022, 10:e1854.
 2.000 TCG
785
S Eck, B Fritz, C Haferlach, J Kunz, T Liehr, S Matos-Meder, H Rieder, D Schäfer, I Schanze.
Web-based external quality assessment (EQA) for genetic diagnostics provided by the German Association of Professionals for Human Genetics (BVDH).
ECA newsletter 2022, 49:2-4.
 n.a. other
784
T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2022, 49:22.
n.a. sSMC
783
S Azawi, M Balachandran, F Kramer, S Kankel, M Rincic, T Liehr.
Molecular cytogenetic characterization of urethane induced murine lung cell line LA-4 as model for human squamous cell lung cancer.
Mol Clin Oncol 2022, 16:9.
1.200 TCG
782
RR Capela de Matos, M Othman, GM Ferreira, K Monteso, MT de Souza, M Rouxinol, JB Melo, IM Carreira, E Abdelhay, T Liehr, RC Ribeiro, M Silva.
Somatic homozygous loss of SH2B3, and a non-Robertsonian translocation t(15;21)(q25.3;q22.1) with NTRK3 rearrangement, in an adolescent with progenitor B-cell acute lymphoblastic leukemia with the iAMP21.
Cancer Genet 2022, 262-263:16-22.
1.900 TCG
29% of publications of Institute of Human Genetics Jena in the actual year

2021
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
781
CF Yano, A Sember, R Kretschmer, LAC Bertollo, T Ezaz, T Hatanaka, T Liehr, P Ráb, A Al-Rikabi, P Ferreira Viana, E Feldberg, EA de Oliveira, GA Toma, MdB Cioffi.
Against the mainstream: exceptional evolutionary stability of l ZW sex chromosomes across fish families Triportheidae and Gasteropelecidae (Teleostei: Characiformes).
Chromosome Res 2021, 29:391-416.
4.620 EVO
780
M Volleth, S Müller, K-G Heller, V Trifonovo, T Liehr, H-S Yong, RJ Baker, FA Aanwarali Khan, CG Sotero-Caio.
Cytogenetic analyses detect cryptic diversity in Megaderma spasma from Malaysia.
Acta Chiropt 2021, 23:271-284.
1.145 EVO
779 4.757 TCG
778 10.900 EVO
777
L Spahiu, E Behluli, R Hadziselimovic, T Liehr, G Temaj.
Mucopolysaccharidosis III: Molecular basis and treatment.
Pediatr Endocrinol Diab Metabol 2021, 27:201-208.
n.a. CG
776
T Liehr.
Molecular cytogenetics in the era of chromosomics and cytogenomic approaches.
Front Genet 2021, 12:720507
4.772 M
775
RLR de Moraes, F de MC Sassi, LAC Bertollo, MM Koh, PF Viana, E Feldberg, VCS Oliveira, GA Deon, ABH Al-Rikabi, T Liehr, M de Bello Cioffi.
Tracking the evolutionary trends among small-sized fishes of the genus Pyrrhulina (Characiformes, Lebiasinidae): New insights from a molecular cytogenetic perspective.
Front Genet 2021, 12:769984.
4.772 EVO
774
O Kadioglu, MEM Saeed, N Mahmoud, S Azawi, K Mrasek, T Liehr, T Efferth.
Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR.
Life Sciences 2021, 284:119601.
6.780 TCG
773
F Santiago, R Tavares Silvestre, U Barros Otero, M Medeiros Tabalipa, M de Moura Ribeiro-Carvalho, L Rios Scherrer, ABH Al-Rikabi, T Liehr, G Alves, MH Ornellas.
The association of three DNA repair genes polymorphisms on the frequency of chromosomal alterations detected by fluorescence in situ hybridization.
Int Arch Occup Environ Health 2021, 94:1567-1577.
2.851 TCG
772
F de MC Sassi, O Moreira-Filho, GA Deon, A Sember, LAC Bertollo, T Liehr, VCS Oliveira, PF Viana, E Feldberg, MR Vicari, M de B Cioffi.
Adding new pieces to the puzzle of karyotype evolution in Harttia (Siluriformes, Loricariidae): Investigation of Amazonian species.
Biology 2021, 10:922.
5.168 EVO
771
M Abdulazeez, S Kankel, T Liehr.
About the origin of the acrocentric part of non-acrocentric satellited chromosomes in humans.
Research Results Biomedicine 2021, 7:215-219.
n.a. HET
770
T Liehr.
International System for Human Cytogenetic or Cytogenomic Nomenclature (ISCN) – some thoughts.
Cytogenet Genome Res 2021, 161:223-224.
1.941 other
769
T Liehr, N Fleischer, A Al-Rikabi.
 Next-generation phenotyping in cat- eye syndrome based on computer-aided facial dysmorphology analysis of normal photographs.
Mol Genet Genomic Med. 2021; 9:e1785.
2.473. sSMC
768
S Tsan, S Kankel, N Padutsch, L Person, M Ziegler, A Al-Rikabi, A Weise, K Mrasek, T Liehr.
About cryptic acrocentric pericentromeric abnormalities in infertile.
OBM Genetics 2021, 5:11.
n.a. CG
766
S Azawi, T Liehr, M Rincic.
First molecular cytogenetic characterisation of tracheal squamous cell carcinoma cell line KLN 205.
J Cancer Metast Treatm 2021, 7:38.
n.a. TCG
765
S Fuchs, J Lisfeld, S Kankel, L Person, T Liehr.
The acrocentric part of der(Y)t(Y;acro)(q12;p1?2) contains D15Z1 sequences in the majority of cases.
Hum Genome Var 2021, 8:32.
n.a. HET
764
       M Volleth, FAA Khan, S Müller, RJ Baker, D Arenas-Viveros, RD Stevens, V Trifonov, T Liehr, K-G Heller, CG Sotero-Caio.
Cytogenetic investigations in Bornean rhinolophoidea revealed cryptic diversity in Rhinolophus sedulus entailing classification of peninsular Malaysia specimens as a new species.
Acta Chiropt 2021, 23:1-20.
1.145 EVO
763
T Liehr, I M Carreira.
PWG: Marker chromosomes.
ECA newsletter 2021, 48:95. 
n.a. sSMC
762
 T Liehr.
Noninvasive prenatal testing (NIPT), what patients do not learn, may be due to lack of specialist genetic training by gynecologists and obstetricians?
Front Genet 2021, 12:682980.
4.772 CG
761
VCS Oliveira, M Altmanová, PF Viana, T Ezaz, LAC Bertollo, P Ráb, T Liehr, A Al-Rikabi, E Fedberg, T Hatanaka, S Scholz, A Meurer, M Cioffi.
Revisiting the karyotypes of alligators and caimans (Crocodylia, Alligatoridae) after a half-century delay: Bridging the gap in chromosomal evolution of reptiles.
Cells 2021, 10:1397.
7.294 EVO
760
 K Piaszinski, M Rincic, T Liehr, S Azawi.
Molecular cytogenetic characterization of the murine melanoma cell lines S91 clone M3 and B16-F1 with variant B16-4A5.
Cytogenet Genome Res 2021, 161:82-92.
1.941 TCG
759
VA Trifonov, MB Cioffi, T Liehr.
Preface.
Cytogenet Genome Res 2021, 161:5.
1.941 other
758
S Ditcharoen, S Khensuwan, K Seetapan, P Soonthornvipat, C Suwannapoom, K Pinthong, S Tongnunui, MdB Cioffi, T Liehr, A Tanomtong, W Supiwong.
First classical and molecular cytogenetic analyses of Sperata acicularis (Siluriformes, Bagridae).
Taiwania 2021, 66:203-213.
0.816 EVO
757
P Yeesin, P Buasriyot, S Ditcharoen, P Chaiyasan, C Suwannapoom, S Juntaree, S Jantarat, S Talumphai, MdB Cioffi, T Liehr, A Tanomtong, W Supiwong.
Comparative study of four Mystus species (Bagridae, Siluriformes) from Thailand: insights into their karyotypic diversity.
Comp Cytogenet 2021, 15:119-136.
1.182 EVO
756
ÁS Roco, T Liehr, A Ruiz-García, K Guzmán, M Bullejos.
Comparative distribution of repetitive sequences in the karyotypes of Xenopus tropicalis and Xenopus laevis (Anura, Pipidae).
Genes 2021, 12:617.
4.141 EVO
755
R Hochstenbach, T Liehr, RJ Hastings.
Chromosomes in the genomic age. Preserving cytogenomic competence of diagnostic genome laboratories.
Europ J Hum Genet 2021, 29:541-552.
5.351 CG
754
KCDA Monteso , MAK Othman, RR Capela de Matos, DR Ney Garcia,  MM da Rocha, MT de Souza, LF Albagli, T Liehr, MGP Land, MLM Silva, ES Costa.
An original complex rearrangement involving chromosomes 9, 11, and 14, harboring a complex KMT2A gene rearrangement in an infant with mixed-phenotype acute leukemia.
J Pediatr Hematol Oncol 2021, 43:e371-e374.
n.a. TCG
753
A Grigoryan, J Pospiech, S Krämer, D Lipka, T Liehr, H Geiger, H Kimura, MA Mulaw, MC  Florian.
Attrition of X chromosome inactivation in aged hematopoietic stem cells.
Stem Cell Reports. 2021, 16:708-716.
7.294 TCG
752
 S Azawi , L-M Barf , T Liehr.
First molecular cytogenetic characterization of the MMT 060562 murine breast cancer cell line.
Research Results Biomedicine 2021, 7:4-14.
n.a. TCG
751
EG Coci, U Koehler, T Liehr, A Stelzner, C Fink, H Langen, J Riedel.
Correction to: CANPMR syndrome and chromosome 1p32-p31 deletion syndrome coexist in two related individuals affected by simultaneous haplo-insufficiency of CAMTA1 and NFIA genes.
Mol Cytogenet 2021;14:17. Erratum for: Mol Cytogenet 2016; 9:10.
1.904 CG
750
T Liehr.
About classical molecular genetics, cytogenetic and molecular cytogenetic data not considered by Genome Reference Consortium and thus not included in genome browsers like UCSC, Ensembl or NCBI
Mol Cytogenet 2021, 14:20.
1.904 CG
749
I Miura, F Shams, S-M Lin, M de Bello Cioffi, T Liehr, A Al-Rikabi, C Kuwana, K Srikulnath, Y Higaki, T Ezaz.
Evolution of a multiple sex-chromosome system by three-sided translocations among potential sex-chromosomes in the Taiwanese frog, Odorrana swinhoana.
Cells 2021, 10:661.
7.666 EVO
748
T Liehr.
Repetitive elements in human.
https://encyclopedia.pub
n.a. HET
747
V Spangenberg, M Arakelyan, E Galoyan, I Martirosyan, A Bogomazova, E Martynova, M de Bello Cioffi, T Liehr, A Al-Rikabi, F Osipov, V Petrosyan, O Kolomiets.
Meiotic synapsis of homeologous chromosomes and mismatch repair protein detection in the parthenogenetic rock lizard Darevskia unisexualis.
Mol Reprod Dev 2021;88:119-127.
2.812 EVO
746
P Chaiyasan, B Mingkwan, S Jantarat, C Suwannapoom, MdB Cioffi, T Liehr, S Talumphai, A Tanomtong, W Supiwong.
Classical and molecular cytogenetics of Belontia hasselti (Perciformes: Osphronemidae): Insights into the ZZ/ZW sex chromosome system.
Biodiversitas 2021, 22:546-554.
n.a. EVO
745
T Liehr, HE Williams, M Ziegler, S Kankel, N Padutsch, Ahmed Al-Rikabi.
Small supernumerary marker chromosomes derived from chromosome 14 and/or 22.
Mol Cytogenet 2021, 14:13.
1.904 sSMC
744
O Kadioglu, M Saeed, N Mahmoud, S Azawi, K Mrasek, T Liehr, T Efferth.
Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion.
Arch Toxicol 2021, 95:959-974.
6.168 TCG
743 19.160 HET
742
T Liehr.
Repetitive elements in human.
Int J Mol Sci 2021, 22:2072.
5.923 HET
741
F Sassi, M Perez, V Oliveira, GA Deon, F Souza, P Ferreira, E Oliveira, T Hatanaka, T Liehr, LAC Bertollo, M de Bello Cioffi.
High genetic diversity despite conserved karyotype organization in the giant trahiras from genus Hoplias (Characiformes, Erythrinidae).
Genes 2021; 12:252.
4.141 EVO
740
ME Rodríguez, I Cross, A Arias-Pérez, S Portela-Bens, MA Merlo, T Liehr, L Rebordinos.
Cytogenomics unveil the transposable elements driving rearrangements in chromosomes 2 and 4 of Solea senegalensis.
Int J Mol Sci 2021, 22:1614.
6.261 EVO
739
M Rincic, M Rados, J Kopic, Z Krsnik, T Liehr.
7p21.3 together with a 12p13.32 deletion in a patient with microcephaly - does 12p13.32 locus possible comprises a candidate gene region for microcephaly?
Front Mol Neuroscience 2021, 4:613091
6.261 CG
738
S Azawi, M Rincic, T Liehr.
Cytogenomic characteristics of murine breast cancer cell line JC.
Mol Cytogenet 2021, 14:7.
1.904 TCG
737
S Azawi, K Piaszinski, M Balachandran, T Liehr, M Rincic.
Molecular cytogenomic characterization of two murine liver cancer cell lines: MH-22A and Hepa 1-6.
J Genet Genomes 2021, 5:1
n.a. TCG
736
IF Alarbeed, A Wafa, F Moassass, B Al-Halabi, W Al-Achkar, T Liehr, I Aboukhamis.
De novo adult acute myeloid leukemia with two new mutations in juxtatransmembrane domain of the FLT3 gene: a case report.
J Med Case Reports 2021, 15:22.
n.a. TCG
735
T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2021, 47:32.
n.a. sSMC
734
O Kadioglua, MEM Saeed, N Mahmoud, SSH Azawi, M Rincic, T Liehr, T Efferth.
Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma.
Life Sciences 2021, 267:11892
6.780 TCG
733
M Weber, A Weise, F Vasheghani, C Göhner, JS Fitzgerald, T Liehr, UR Markert.
Cytogenomics of six human trophoblastic cell lines.
Placenta 2021, 103:72-75.
3.287 TCG
75% of publications of Institute of Human Genetics Jena in the actual year

2020
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
732
V Velissariou, F Sachinidi, S Christopoulou, L Florentin, T Liehr, A Efthymiadou, E Angelopoulou, D Chrysis, EG Stefanou.
Low-level trisomy 14 mosaicism: A carrier of an isochromosome 14 and a supernumerary marker chromosome 14.
Cytogenet Genome Res 2020, 160:664-670.
1.636 sSMC
731
M Manferrari, M Rincic, T Liehr, S Azawi.
Cytogenomics of murine melanoma cell lines C57/B1 and B16-F0.
Mol Exp Biol Med 2020, 3:39-44.
n.a. TCG
730
GA Deon, L Glugoski, MR Vicari, V Nogaroto, F de Menezes C Sassi, M de Bello Cioffi, T Liehr, LAC Bertollo, OM Filho.
Highly rearranged karyotypes and multiple sex chromosome systems in armored catfishes from the genus Harttia (Teleostei, Siluriformes).
Genes 2020, 11:1366.
4.096 EVO
729
V Spangenberg, O Kolomiets, I Stepanyan, E Galoyan, MdB Cioffi, E Martynova, I Martirosyan, T Grishaeva, F Danielyan, A Al-Rikabi, T Liehr, M Arakelyan.
Evolution of the parthenogenetic rock lizard hybrid karyotype: Robertsonian translocation between two maternal chromosomes in Darevskia rostombekowi.
Chromosoma 2020, 129:275-283.
4.316 EVO
728
M Chaplin, JJ Kirkham, K Dwan, DJ Sloan, G Davies, AL Jorgensen (T Liehr was Delphi participant)
STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline.
PLoS Med 2020, 17:e1003344.
n.a. other
727
S Ditcharoen, FMC Sassi, LAC Bertollo, WF Molina, T Liehr, P Saenjundaeng, A Tanomtong, W Supiwong, C Suwannapoom, MB Cioffi.
Comparative chromosomal mapping of microsatellite repeats reveals divergent patterns of accumulation in 12 Siluridae (Teleostei: Siluriformes) species.
Genet Mol Biol 2020, 43:e20200091.
1.771 EVO
726
T Harutyunyan, A Al-Rikabi, A Sargsyan, G Hovhannisyan, R Aroutiounian, T Liehr.
Doxorubicin-induced translocation of mtDNA into the nuclear genome of human lymphocytes detected using a molecular-cytogenetic approach.
Int J Mol Sci 2020; 21:7690. 
5.923 TCG
725
I Joksic, T Liehr, M Toljic, N Karadzov-Orlic, Z Milovanovic, Z Mikovic, A Egic.
Prenatal ultrasonographic manifestations of partial trisomy 12q (12q24.2→qter) and partial monosomy 2q (2q37.3→2qter).
Vojnosanit Pregl 2020, 77:754-757.
  0.430 CG
724
FdMC Sassi, GA Deon, O Moreira-Filho, MR Vicari, LAC Bertollo, T Liehr, EAd Oliveira, MB Cioffi.
Multiple sex chromosomes and evolutionary relationships in amazonian catfishes: The outstanding model of the genus harttia (Siluriformes: Loricariidae).
Genes 2020, 11:1179.476.
4.096 EVO
723
PF Viana, T Ezaz, MdB Cioffi, T Liehr, A Al‐Rikabi, R Tavares‐Pinheiro, LAC Bertollo, E Feldberg.
Revisiting the karyotype evolution of neotropical boid snakes: A puzzle mediated by chromosomal fissions.
Cells 2020, 9:2268.
6.600 EVO
722
N Ziller, R Kotolloshi, M Esmaeili, M Liebisch, R Mrowka, A Baniahmad, T Liehr, G Wolf, I Loeffler.
Sex differences in diabetes- and TGF-β1-induced renal damage.
Cells 2020, 9:2236.
6.600 CG
721
H Sheth, S Trivedi, T Liehr, K Patel, D Jain, J Sheth, F Sheth.
Mosaic chromosome 18 anomaly delineated in a child with dysmorphism using a three-pronged cytogenetic techniques approach: a case report.
BMC Medical Genomics 2020, 13:141.
 3.063 CG
720
VI Romero, JC Pozo, S Saenz, A Llamos-Paneque, T Liehr, K Hosomichi, A Tajima.
A toddler with phylloid-type pigmentary mosaicism and ambiguous genitalia resulting from trisomy 14 induced by a der(Y)t(Y;14).
Hum Genome Var 2020, 7:28.
 n.a. CG
719
A Wafa, RA Jarjour, D Alolabi, T Liehr, O Hamdan, JB Melo, IM Carreira, MAK Othman, W Al‑Achkar.
A new childhood ALL case with an extremely complex karyotype and acute spontaneous tumor lysis syndrome.
Mol Cytogenet 2020, 13:44
2.009 TCG
718
E Wahlbul, T Liehr, M Rincic, S Azawi.
Cytogenomic characterization of three murine malignant mesothelioma tumor cell lines.
Mol Cytogenet 2020, 13:43.
2.009 TCG
717
 PF Viana, E Feldberg, MB Cioffi , VT de Carvalho, S Menezes, RC Vogt, T Liehr, T Ezaz.
The amazonian red side-necked turtle Rhinemys rufipes (Spix, 1824) (Testudines, Chelidae) has a GSD sex-determining mechanism with an ancient XY sex microchromosome system.
Cells 2020, 9:2088.
 6.600 EVO
716
M Pissaparn, S Phimphan, P Chaiyasan, A Tanoamting, T Liehr, C Suwannapoom, M Reungsing, W Supiwong.
First chromosome analysis of Thai pufferfish Pao cochinchinensis (Steindachner, 1866).
Biodiversitas 2020, 21:4309-4316.
n.a. EVO
715
A Al-Rikabi, L-B Liehr, T Liehr.
Glass-needle based chromosome microdissection – how to set up probes for molecular cytogenetics?
Video J Clin Res 2020, 2:100004VAM08AR2020.
 n.a. M
714
T Liehr.
Is molecular cytogenetic diagnostics of rare diseases in Europe close to extinction.
J Genet Genom 2020, 4:2.
 n.a. other
713
C Sismani, S-M Rapti, P Iliopoulou, A Spring, R Neroutsou, M Lagou, M Robola, E Tsitsopoulos, L Kousoulidou, A Alexandrou, I Papaevripidou, A Theodosiou, M Syrrou, S Fuchs, M Hempel, D Huhle, T Liehr, M Ziegler, M Duesberg, V Velissariou.
Novel pericentric inversion inv(9)(p23q22.3) in unrelated individualswith fertility problems in the Southeast European population.
J Hum Genet 2020, 65:783-795.
 3.172 CG
712
W Slimani, A Jelloul, A Al-Rikabi, A Sallem, Y Hasni, S Chachia, A Ernez, A Chaieb, M Bibi, T Liehr, A Saad, S Mougou-Zerelli.
Small supernumerary marker chromosomes (sSMC) and male infertility: characterization of five new cases, review of the literature, and perspectives.
J Assist Reprod Genet 2020, 37:1729-1736.
 3.412 sSMC
711
M Zamariolli, A Di-Battista, M Moyses-Oliveira, CB de Mello, MA Ramos, T Liehr, MI Melaragno.
Disruption of PCDH10 and TNRC18 genes due to a balanced translocation.
Cytogenet Genome Res 2020, 160:321-328.
 1.636 CG
710
H Hamdaoui, A Natiq, O Benlarroubia, T Liehr, H Dehbi, L Loukhmas, F Chegdani.
Near tetrapoloid karyotype with translocation t(11;14) in a Moroccan patient with amyloid light-chain amyloidosis and multiple myeloma.
Leuk Res Rep 2020, 14:100217.
 n.a. TCG
709
P Viana, T Ezaz, M Cioffi, T Liehr, A Al-Rikabi, L Goll, A Rocha, E Feldberg.
Landscape of snake’ sex chromosomes evolution spanning 85MYR: Ancestry or co-opted sequences acquisition along their evolution?
Scient Rep 2020, 10:12499.
 4.379 EVO
708
A Wafa, F Moassass, S Almedani, T Liehr, K Wilhelm, M As'sad, S Knippenberg, R Glaubitz, RA Jarjour, W Al Achkar.
A novel heterozygous variant in exon 32 of the CHD7 gene (c.6923C>T) in a Syrian family with Kallmann syndrome.
Res Results Biomed 2020, 6:154-159.
 n.a. CG
707
A Wafa, RA Jarjour, A Aljapawe, S ALmedania, T Liehr, JB Melo, IM Carreira, MAK Othman, W Al-Achkar.
An acquired stable variant of a dicentric dic(9;20) and complex karyotype in a Syrian childhood B-acute lymphoblastic leukemia case.
Mol Cytogenet 2020, 13:29.
 2.009 TCG
706
A Garcia-Angulo, MA Merlo, R Itiga, ME Rodriguez, S Portella-Bens, A Al-Rikabi, T Liehr, L. Rebordinos.
Gene clusters related to metamorphosis in Solea senegalensis are highly conserved.
Comp Biochem Physiol D 2020, 35:100706.
2.674 EVO
705
A Azawi, T Liehr, M Rincic, M Manferrari.
Molecular cytogenomic characterization of the murine breast cancer cell lines C-127I, EMT6/P and TA3 Hauschka.
Int J Mol Sci 2020, 21:4716.
 5.923 TCG
704
 AF de Figueiredo, MGP Land, GM Ferreira, A Mencalha, R Binato, RR Capela de Matos, T Liehr, MLM Silva, E Abdelhay.
Clinical and biological correlates of the expression of select Polycomb complex genes in Brazilian children with acute promyelocytic leukaemia.
Br J Haematol 2020, 189:e222-e265. 		5.923 TCG
703
 K Gadsbøll, OB Petersen, V Gatinois, H Strange, B Jacobsson, R Wapner, JR Vermeesch; NIPT-map Study Group (including T Liehr), I Vogel.
Current use of noninvasive prenatal testing in Europe, Australia and the USA: A graphical presentation.
Acta Obstet Gynecol Scand 2020, 99:722-730. 		3.636 CG
702
 BP Potlapalli, V Schubert, J Metje-Sprink, T Liehr, A Houben.
Application of Tris-HCl allows the specific labelling of regularly prepared chromosomes by CRISPR-FISH.
Cytogenet Genome Res 2020, 160:156-165.   		1.636 M
701
  V Spangenberg, M Arakelyan, M Cioffi, T Liehr, A Al-Rikabi, E Martynova, I Stepanyan, F Danielyan, E Galoyan, O Kolomiets.
Cytogenetic mechanisms of unisexuality in rock lizards.
Scient Rep 2020, 10:8697. 		4.379 EVO
700
 M Volleth, M Zenker, I Joksic, T Liehr.
Long-term culture of EBV-induced human lymphoblastoid cell lines reveals chromosomal instability.
J Histochem Cytochem 2020, 68:239-251. 		2.479 CG
M
699
 RA Pilz, K Schwefel, A Weise, T Liehr, P Demmer, A Spuler, S Spiegler, E Gilberg, CA Hübner, U Felbor, M Rath.
First interchromosomal insertion in a patient with cerebral and spinal cavernous malformations.
Sci Rep 2020, 10:6306.  		4.379 CG
698
 WF Molina, GWWF Costa, IMC Cunha, LAC Bertollo, T Ezaz,  T Liehr, MB Cioffi.
Molecular cytogenetic analysis in freshwater prawns of the genus Macrobrachium (Crustacea: Decapoda: Palaemonidae).
Int J Mol Sci 2020, 21:E2599. 		5.923 EVO
697
 FMC Sassi, T Hatanaka, RLR Moraes, GA Toma, EA Oliveira, T Liehr, P Rab, LAC Bertollo, PF Viana, E Feldberg, M Nirchio, MMF Marinho, JFSE Souza, MB Cioffi.
An insight into the chromosomal evolution of Lebiasinidae (Teleostei, Characiformes).
Genes (Basel) 2020, 11:E365. 		4.096 EVO
696
 MAK Othman, M Đurišić, G Samardzija, D Vujić, N Lakic, Z Zecevic, F Al-Shaheri, R Aroutiounian, JB Melo, IM Carreira, B Meyer, T Liehr.
Complex karyotype with cryptic FUS gene rearrangement and deletion of NR3C1 and VPREB1 genes in childhood B-cell acute lymphoblastic leukemia: A case report.
Oncol Lett 2020, 19:2957-2962 . 		2.967 TCG
695
 A Zlotina, A Maslova, O Pavlova, N Kosyakova, A Al-Rikabi, T Liehr, A Krasikova.
New insights into chromomere organization provided by lampbrush chromosome microdissection and high-throughput sequencing.
Frontiers in Genetics 2020, 11:57. 		4.599 EVO
INT
694
 RT Silvestre, M Bravo, F Santiago, L Delmonico, L Scherrer, U Barros Otero, T Liehr, G Alves, M Chantre-Justino, MH Ornellas.
Hypermethylation in gene promoters are induced by chronic exposure to benzene, toluene, ethylbenzene and xylenes.
Pak J Biol Sci 2020, 23:518-525. 		n.a. TCG
693
 LA Mendez Rosado, D García, O Molina, A García, N de León, A Lantigua-Cruz, T Liehr.
Diagnostico citogenetico molecular en pacientes con trastornos del neurodesarrollo.
Arch Argentin Pediat 2020, 118:52-55. 		0.635 CG
692
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2020, 45:6-7.
 		n.a. sSMC
691
 		IP Ribeiro, IM Carreira, L Esteves, F Caramelo, T Liehr, JB Melo.
Chromosomal breakpoints in a cohort of head and neck squamous cell carcinoma patients.
Genomics 2020, 112:297-303.
 		5.736 TCG
690
 		J Thielker, A Weise, MAK Othman, IM Carreria, JB Melo, F von Eggeling, O Guntinas-Lichius, M Ziegler, T Liehr.
Molecular cytogenetic pilot study on pleomorphic adenoma of salivary gland.
Oncol Lett 2020, 19:1125-1130.
 		2.967 TCG
63% of publications of Institute of Human Genetics Jena in the actual year


2019
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
689
 		P Brown, RELISH Consortium (including T Liehr), Y Zhou.
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Database 2019, 1:2019:baz08. 		2.593 M
688
 		GA Toma, RLR de Moraes, FMC Sassi, LAC Bertollo, EA de Oliveira, P Rab, A Sember, T Liehr, T Hatanaka, PF Viana, MMF Marinho, E Feldberg, MB Cioffi.
Cytogenetics of the small-sized fish, Copeina guttata (Characiformes, Lebiasinidae): Novel insights into the karyotype differentiation of the family.
PLoS One 2019, 14:e0226746.
2.740
 		EVO
687
 		A Al-Rikabi, MdB Cioffi, T Liehr.
Chromosome microdissection on semi-archived material.
Cytometry A 2019, 95:1285-1288.		 3.124 M
EVO
686
J Mol Genet Med 2019, 13:1000439.
 n.a. sSMC
685
 		T Liehr, A Weise, K Mrasek, M Ziegler, N Padutsch, K Wilhelm, A Al-Rikabi.
Recombinant chromosomes resulting from parental pericentric inversions - Two new cases and a review of the literature.
Front Genet 2019, 10:1165.		 3.258 CG
684
 		T Liehr, A Al-Rikabi.
Mosaicism: Reason for normal phenotypes in carriers of small supernumerary marker chromosomes with known adverse outcome. A Systematic Review.
Front Genet 2019, 10:1131.		 3.258
 		sSMC
683
 		E García, I Cross, S Portela-Bens, ME Rodríguez, A García-Angulo, B Molina, A Cuadrado, T Liehr, L Rebordinos.
Integrative genetic map of repetitive DNA in the sole Solea senegalensis genome shows a Rex transposon located in a proto-sex chromosome.
Sci Rep 2019, 9:17146.		 3.998
 		EVO
682
 		VE Gokhman, MB Cioffi, C König, M Pollmann, C Gantert, L Krogmann, JML Steidle, N Kosyakova, T Liehr, A Al-Rikabi.
Microdissection and whole chromosome painting confirm karyotype transformation in cryptic species of the Lariophagus distinguendus (Förster, 1841) complex (Hymenoptera: Pteromalidae).
 PLoS One 2019, 14:e0225257.		 2.740
 		EVO
681
 		T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2019, 43:14-15.		 n.a.
 		sSMC
680
 		T Liehr.
Report from the European Board of Medical Genetics.
ESHG Newsletter 2019, 34:11-12.		 n.a. other
679
 		T Liehr.
Non-invasive prenatal testing – safer or simply more profitable?
https://atlasofscience.org/non-invasive-prenatal-testing-safer-or-simply-more-profitable/		 n.a. PRE
M
678
 		ME Rodríguez, B Molina, MA Merlo, A Arias-Pérez, S Portela-Bens, A García-Angulo, I Cross, T Liehr, L Rebordinos.
Evolution of the proto sex-chromosome in Solea senegalensis.
Int J Mol Sci 2019, 20:5011.		 4.556
EVO
677
 		IP Ribeiro, JM Rodrigues, A Mascarenhas, V Marques, F Caramelo, MJ Julião, T Liehr, JB Melo, IM Carreira.
 (Cyto)genomic and epigenetic characterization of BICR 10 cell line and three new established primary human head and neck squamous cell carcinoma cultures.
Genes Genomics 2019, 41:1207-1221.
 		1.188 TCG
676
 		A Zlotina, A Maslova, N Kosyakova, AB Hamid Al-Rikabi, T Liehr, A Krasikova.
Heterochromatic regions in Japanese quail chromosomes: comprehensive molecular-cytogenetic characterization and 3D mapping in interphase nucleus.
Chromosome Res 2019, 27:253-270.
 		3.413 EVO
INT
675
 		IY Iourov, T Liehr, SG Vorsanova, LA Mendez-Rosado, YB Yurov.
The applicability of interphase chromosome-specific multicolor banding (ICS-MCB) for studying neurodevelopmental and neurodegenerative disorders.
Res Results Biomed 2019, 5:4-9.
n.a. INT
674
 		G Hovhannisyan, T Harutyunyan, R Aroutiounian, T Liehr.
DNA copy number variations as markers of mutagenic impact.
Int J Mol Sci 2019, 20:4723.		 4.556 TCG
673
 		FHS Souza, MF Perez, LAC Bertollo, EA Oliveira, S Lavoué, C Gestich, P Ráb, T Ezaz, T Liehr, PF Viana, E Feldberg, MB Cioffi.
Interspecific genetic differences and historical demography in South American arowanas (Osteoglossiformes, Osteoglossidae, Osteoglossum).
Genes 2019, 10:693.
 		3.759 EVO
672
 		MdB Cioffi, P Ráb, T Ezaz, LAC Bertollo, S Lavoué, EA de Oliveira, A Sember, WF Molina, FHS de Souza, Z Majtánová, T Liehr, ABH Al-Rikabi, CF Yano, P Viana, E Feldberg, P Unmack, T Hatanaka, A Tanomtong, MF Perez.
Deciphering the evolutionary history of Arowana fishes (Teleostei, Osteoglossiformes, Osteoglossidae): Insight from comparative cytogenomics.
Int J Mol Sci 2019, 20:4296.
 		4.556 EVO
671
 		GWWF da Costa, MdB Cioffi, T Liehr, E Feldberg, LAC Bertollo, WF Molina.
Extensive chromosomal reorganization in Apistogramma fishes (Cichlidae, Cichlinae) fits the complex evolutionary diversification of the genus.
Int J Mol Sci 2019, 20:4077.
 		4.556 EVO
670
 		RLR de Moraes, A Sember, LAC Bertollo, EA De Oliveira, P Rab, T Hatanaka, MMF Marinho, T Liehr, ABH Al-Rikabi, E Feldberg, PF Viana, M De Bello Cioffi.
Comparative cytogenetics and neo-Y formation in small-sized fish species of the genus Pyrrhulina (Characiformes, Lebiasinidae).
Front Genet 2019, 10:67. 		3.258 EVO
696
 		H Merhni, M Zerkaoui, A Natiq, A Sbiti, T Liehr, A Sefiani.
Constitutional partial proximal trisomy 14q11.2 to 14q21: two new Moroccan cases and review of the literature.
OBM Genetics 2019, 3:1903085.
 		n.a. CG
695
 		D Xu, A Sember, Q Zhu, EA de Oliveira, T Liehr, ABH Al-Rikabi, Z Xiao, H Song, M Cioffi.
Deciphering the origin and evolution of a unique X1X2Y system in two closely related Oplegnathus species (Oplegnathidae, Centrarchiformes).
Int J Mol Sci 2019, 20:3570.
 		4.556 EVO
694
 		S Ditcharoen, LAC Bertollo, P Rab, E Hnátková, WF Molina, T Liehr, A Tanomtong, C Triantaphyllidis, C Ozouf-Costaz, S Tongnunui, P Pengseng, W Supiwong, R Aroutiounian, M Cioffi.
Genomic organization of repetitive DNA elements and extensive karyotype diversity of Silurid catfishes (Teleostei: Siluriformes): A comparative cytogenetic approach.
Int J Mol Sci 2019, 20:3545.		 4.556 EVO
693
 		T Liehr, IM Carreira, Z Balogh, ED Garrido, I Verdorfer, DA Coviello, L Florentin, H Scheffer, M Rincic, HE Williams.
Regarding the rights and duties of Clinical Laboratory Geneticists in genetic healthcare systems; results of a survey in over 50 countries.
Eur J Hum Genet 2019, 27:1168-1174.
 		3.657 other
692
 		R De Matos, D Ney Garcia, M Othman, G Ferreira, J Melo, I Carreira, C Meyer, R Marschalek, E Costa, M Land, T Liehr, R Ribeiro, M Macedo Silva.
A new complex karyotype involving a KMT2A-r variant three-way translocation, in a rare clinical presentation of a pediatric patient with acute myeloid. leukemia.
Cytogenet Genome Res 2019, 157:213-219
 		1.114 TCG
691
 		A Garcia-Angulo, MA Merlo, ME Rodriguez, S Portela-Bens, T Liehr, L Rebordinos.
Genome and phylogenetic analysis of genes involved in the immune system of Solea senegalensis - potential applications in aquaculture.
Front Genet 2019, 10:529.
 		3.258 EVO
690
 		T Liehr, LB Liehr.
An update on small supernumerary marker chromosomes (sSMC).
Res Results Biomed 2019, 5:4-6.  		n.a. sSMC
689
 		W Al-Achkar, M As’sad, T Liehr, A Ikhtiar, A Wafa.
A de novo childhood case of T-cell lymphoblastic leukemia with high hyperdiploid karyotype carrying an unreported balanced translocation t(X;5)(q26;q31.3~32) in a male patient.
OBM Genetics 2019, 3:1902081.
 		n.a. CG
688
 		FMC Sassi, EA de Oliveira, LAC Bertollo, M Nirchio, T Hatanaka, MMF Marinho, O Moreira-Filho, R Aroutiounian, T Liehr, ABH Al-Rikabi, MB Cioffi.
Chromosomal evolution and evolutionary relationships of Lebiasina species (Characiformes, Lebiasinidae).
Int J Mol Sci 2019, 20:E2944.		 4.556 EVO
687
 		IA Pessôa, CK Amorim, WAS Ferreira, F Sagica, JR Brito, M Othman, B Meyer, T Liehr, EHC de Oliveira.
Detection and correlation of single and concomitant TP53, PTEN and CDKN2A alterations in gliomas.
Int J Mol Sci 2019, 20:2658.		 4.556 TCG
686
 		T Harutyunyan, G Hovhannisyan, A Sargsyan, B Grigoryan, AH Al-Rikabi, A Weise, T Liehr, R Aroutiounian.
Analysis of copy number variations induced by ultrashort electron beam radiation in human leukocytes in vitro.
Mol Cytogenet 2019, 12:18.
 		1.233 TCG
685
 		M Moysés-Oliveira, A Di-Battista, M Zamariolli, VA Meloni, S Bragagnolo, DM Christofolini, CE Steiner, N Kosyakova, T Liehr, A Reymond, MI Melaragno.
Breakpoint mapping at nucleotide resolution in X-autosome balanced translocations associated with clinical phenotypes.
Eur J Hum Genet 2019, 27:760-771.
 		3.657 CG
684
 		N Padutsch, T Liehr.
First report on a 20qh+ heteromorphism characterized by molecular cytogenetics as amplification of D20Z1 sequences.
Res Results Biomed 2019, 5:22-24.
 		n.a. HET
683
 		R Steinacker, T Liehr, N Kosyakova, M Rincic, SS Hussein Azawi.
Molecular cytogenetic characterization of two murine cancer cell lines derived from salivary gland.
Biol Commun 2019, 63:243-255.		 n.a. TCG
682
 		EA de Oliveira, LAC Bertollo, P Rab, T Ezaz, CF Yano, T Hatanaka, OI Jegede, A Tanomtong, T Liehr, A Sember, SR Maruyama, E Feldberg, PF Viana.
Cytogenetics, genomics and biodiversity of the South American and African Arapaimidae fish family (Teleostei, Osteoglossiformes).
PLoS One 2019, 14:e0214225.		 2.740 EVO
681
 		W Supiwong, K Pinthong, K Seetapan, P Sanjundaeng, LAC Bertollo, E Aguiar de Oliveira, CF Yano, T Liehr, S Phimphan, A Tanomtong, M de Bello Cioffi.
Karyotype diversity and evolutionary trends in the Asian swamp eel Monopterus albus (Synbranchiformes, Synbranchidae). A case of chromosomal speciation?
BMC Evolutionary Biology 2019, 19:73.
 		3.058 EVO
680
 		JP Chaudhuri, S Karamanov, L Scott, T Liehr, JU Walther.
Leukocyte nucleus reveals a linear order of chromosomes separated in two parental genomes that favors the process of gene activation.
J Histochem Cytochem 2019, 67:151-158.
 		2.187 INT
679
 		NE Kurtas, L Xumerle, U Giussani, A Pansa, L Cardarelli, V Bertini, A Valetto, T Liehr, C Bonaglia, E Errichiello, M Delledonne, O Zuffardi.
Insertional translocation involving an additional non-chromothriptic chromosome in constitutional chromothripsis: rule or exception?
Mol Genet Genomic Med 2019, 7:e496.
 		1.995 CG
INT
678
 		MLRDR Borges, EM Soares-Ventura, T Liehr, TJ Marques-Salles.
Minimally differentiated acute myeloid leukemia wth ring/marker derived chromosome 7 in a child with Down syndrome.
Hematol Transfus Cell Ther 2019, 41:84-88.
 		n.a. TCG
677
 		A Weise, K Mrasek, C Pentzold, T Liehr.
Chromosomes in the DNA era: Perspectives in diagnostics and research.
Med Genetik 2019, 31:8-19.		 0.964 M
676
 		T Liehr.
From human cytogenetics to human chromosomics.
Int J Mol Sci 2019, 20:826.
 		4.556 M
675
 		FF Barby, LAC Bertollo, EA de Oliveira, CF Yano, T Hatanaka, P Ráb, A Sember, T Ezaz, R Ferreira Artoni, T Liehr, ABH Al-Rikabi, V Trifonov, EHC de Oliveira, WF Molina, OI Jegede, A Tanomtong, M de Bello Cioffi.
Emerging patterns of genome organization in Notopteridae species (Teleostei, Osteoglossiformes) as revealed by Zoo-FISH and Comparative Genomic Hybridization (CGH).
Scient Rep 2019, 9:1112.
 		3.998 EVO
674
 		A Krumbholz, J Roempke, T Liehr, M Groth, A Meerbach, M Schacke, G Maschkowitz, H Fickenscher, W Klapper, A Sauerbrei, P Wutzler, R Zell.
Macaca arctoides gammaherpesvirus 1 (strain herpesvirus Macaca arctoides): virus sequence, phylogeny and characterisation of virus-transformed macaque and rabbit cell lines.
Medic Microbiol Immunol 2019, 208:109-129.
 		1.961 TCG
673
 		NE Kurtas, L Xumerle, L Leonardelli, M Delledonne, A Brusco, K Chrzanowska, A Schinzel, D Larizza, S Guerneri, F Natacci, MC Bonaglia, P Reho, E Manolakos, T Mattina, F Soli, A Provenzano, AH Al-Rikabi, E Errichiello, L Nazaryan-Petersen, S Giglio, N Tommerup, T Liehr, O Zuffardi.
Small supernumerary marker chromosomes: a legacy of trisomy rescue.
Hum Mutat 2019, 40:193-200.		 4.124 sSMC
80% of publications of Institute of Human Genetics Jena in the actual year

2018
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
672
 		T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2018, 41:17.		 n.a.
 		sSMC
671
 		Deutsche Gesellschaft für Humangenetik e.V. (GfH), Berufsverband Deutscher Humangenetiker e.V (T Liehr and A Weise included in commission).
S2k-Leitlinie Humangenetische Diagnostik und Genetische Beratung.
Med Genetik 2018, 30:469-522.		 0.104 other
670
 		L Castiglia, R Husain, I Marquardt, C Fink, T Liehr, D Serino, Melia, E Coci.
7q11.23 micro-duplication syndrome: neuro-physiological and neuro-radiological insights into a rare chromosomal disorder.
J Intellect Disab Res 2018, 62:359-370.
 		1.941 CG
669
 		MH Ornellas, MC Maioli, S Lucena, E Bastos, TS Chaves, K Vieira de Melo, M Carvalho, T Liehr. Complex karyotype including ring 11 chromosome in woman with acute myeloid leukemia.
São Paulo Medical Journal 2018, 136:361-367.
 		1.423 TCG
668
 		V Čulić, R Lasan-Trcić, T Liehr, IN Lebedev, M Pivić, J Pavelic, R Vulić.
A familial small supernumerary marker chromosome 15 associated with cryptic mosaicism with two different additional marker chromosomes derived de novo from chromosome 9: Detailed case study and implications for recurrent pregnancy loss.
Cytogenet Genome Res 2018, 156:179-184.		 1.423 sSMC
667
 		T Araújo, A Khayat, L Quintana, D Calcagno, R Mourão, A Modesto, J Paiva, A Lima, F Moreira, E Oliveira, M Souza, M Othman, T Liehr, E Abdelhay, R Gomes, S Santos, P Assumpção.
Piwi like RNA-mediated gene silencing 1 gene as a possible major player in gastric cancer.
World J Gastroenterol 2018, 24:5338-5350.
 		3.411 TCG
666
 		T Liehr.
Importance of databases for human genetic diagnostics.
J Genet Genom 2018, 2:e105.
4.650 CG
665
 		T Liehr, I Schreyer, K Mrasek, A Weise.
Neue Entwicklungen in der humangenetischen pränatalen Diagnostik.
Ärzteblatt Thüringen 2018, 12:689-691.
 		n.a. CG
PRE
664
 		T Liehr, AB Hamid Al-Rikabi.
Impaired spermatogenesis due to small supernumerary marker chromosomes: The reason for infertility is only reliably ascertainable by cytogenetics.
Sex Dev 2018, 12:281-287.		 2.250 sSMC
663
 		I Cross, S Portela-Bens, A García-Angulo, MA Merlo, ME Rodríguez, T Liehr, L Rebordinos.
A preliminary integrated genetic map distinguishes every chromosome pair and locates essential genes related to abiotic adaptation of Crassostrea angulata/gigas.
BMC Genet 2018, 19:104.
 		2.547 EVO
662
 		A García-Angulo, MA Merlo, S Portela-Bens, ME Rodríguez, E García, A Al-Rikabi, T Liehr, L Rebordinos.
Evidence for a Robertsonian fusion in Solea senegalensis (Kaup, 1858) revealed by zoo-FISH and comparative genome analysis.
BMC Genomics 2018, 19:818.
 		3.501 EVO
661
 		A Grigoryan, N Guidi, K Senger, T Liehr, K Soller, G Marka, A Vollmer, Y Markaki, H Leonhardt, C Buske, D Lipka, C Plass, Y Zheng, MA Mulaw, H Geiger, MC Florian.
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells.
Genome Biology 2018, 19:18. 		14.028 INT
TCG
660
 		A Arias-Pérez, D Ramírez-Torres, ME Rodríguez, S Portela-Bens, E García-Suarez, MA Merlo, A García-Angulo, I Cross, T Liehr, L Rebordinos.
In silico detection and FISH location of miRNAs in Solea senegalensis chromosomes using BACs.
OBM Genet 2018, 2:1804044. 
n.a. EVO
659
 		F Sheth, T Liehr, V Shah, H Sheth, S Tewari, D Solanki, S Trivedi, J Sheth.
A child with intellectual disability and dysmorphism due to complex ring chromosome 6: Identification of molecular mechanism with review of literature.
Ital J Pediatr 2018, 44:114.
1.726 CG
658
 		MAK Othman, B Grygalewicz, A Kołkowska-Leśniak, JB Melo, IM Carreira, T Liehr.
Cryptic NUP214-ABL1 fusion with complex karyotype, episomes and intra-tumor genetic heterogeneity in a T-cell lymphoblastic lymphoma.
 J Cancer Metastasis Treat 2018, 4:50.
 		n.a. TCG
657
 		H Rhode, T Liehr, N Kosyakova, M Rinčic, SSH Azawi.
Molecular cytogenetic characterization of two murine colorectal cancer cell lines.
OBM Genetics 2018, 2:1803037.
 		n.a. TCG
656
 		A Wafa, S ALmedania, A Aljapawe, T Liehr, SE Soulaiman, R Mouna, MAK Othman, W ALachkar.
A new adult AML case with an extremely complex karyotype, remission and relapse combined with high hyperdiploidy of a normal chromosome set in secondary AML.
BMC Hematology 2018, 18:21.		 n.a. TCG
655
 		P Saenjundaeng, M de Bello Cioffi, E Aguiar de Oliveira, A Tanomtong, W Supiwong, S Phimphan, MJ Collares-Pereira, A Sember, LAC Bertollo, T Liehr, CF Yano, T Hatanaka, P Rab.
Chromosomes of Asian cyprinid fishes: Cytogenetic analysis of two representatives of small paleotetraploid tribe Probarbini.
Mol Cytogenet 2018, 11:51.
 		1.331 EVO
654
 		F Sheth, T Liehr, K Mrasek, J Andrieux, S Tewari, N Lubna, J Sheth.
sSMC characterization in a male with Turner syndrome stigmata.
OBM Genetics 2018, 2:1803033.
 		n.a. sSMC
653
 		T Hatanaka, EA de Oliveira, P Ráb, CF Yano, LAC Bertollo, T Ezaz, OOI Jegede, T Liehr, VF Olaleye, M de Bello Cioffi.
First chromosomal analysis in Gymnarchus niloticus (Gymnarchidae, Osteoglossiformes): Insights into the karyotype evolution of this ancient fish order.
Biol J Linn Soc 2018, 125:83-92.
 		2.203 EVO
652
 		PG Maass, A Weise, K Rittscher, J Lichtenwald, AR Barutcu, T Liehr, A Aydin, Y Wefeld‐Neuenfeld, L Pölsler, S Tinschert, JL Rinn, FC Luft, S Bähring.
 Reorganization of inter‐chromosomal interactions in the 2q37‐deletion syndrome.
EMBO J 2018, 37:e96257 .
 		11.227 INT
CG
651
 		FF Barby, P Ráb, S Lavoué, T Ezaz, LAC Bertollo, A Kilian, SR Maruyama, EA de Oliveira, RF Artoni, MH Santos, OI Jegede, T Hatanaka, A Tanomtong, T Liehr, M de Bello Cioffi.
From chromosomes to genome: Insights into the evolutionary relationships and biogeography of old world knifefishes (Notopteridae; Osteoglossiformes).
Genes 2018, 9:306 .
 		3.331 EVO
650
 		S Akbaroghli, SH Tonekaboni, R Kariminejad, T Liehr, EG Coci.
De novo interstitial 2.33 Mb deletion in 8q24.3: New insights on a very rare partial monosomy syndrome.
Clin Dysmorphol 2018, 27:97-100.
 		0.760 CG
649
 		PK Priya, VV Mishra , T Liehr, M Ziegler, S Tiwari, A Patel, SS Chettiar, H Patel.
Characterization of a complex chromosomal rearrangement involving chromosomes 1, 3 and 4 in a slightly affected male partner with unsuccessful obstetric history.
J Assist Reprod Genet 2018, 35:721-725.
 		2.820 CG
648
 		T Liehr, ABH Al-Rikabi, N Kosyakova, M Ziegler.
User-friendly approach to gain isolation of interphase cells for fluorescence in situ hybridization.
OBM Genetics 2018, 2:021.
 		n.a. M
647
 		MB Cioffi, A Sánchez, JA Marchal, N Kosyakova, T Liehr, V Trifonov, LAC Bertollo.
Correction to: Whole chromosome painting reveals independent origin of sex chromosomes in closely related forms of a fish species.
Genetica 2018, 146:123.
 		1.229 EVO
646
 		IP Ribeiro, JM Rodrigues, A Mascarenhas, N Kosyakova, F Caramelo, T Liehr, JB Melo, IM Carreira.
Cytogenetic, genomic, and epigenetic characterization of the HSC-3 tongue cell line with lymph node metastasis.
J Oral Sci 2018, 60:70-81.
 		1.104 TCG
645
 		E Aguiar de Oliveira, A Sember, LAC Bertollo, CF Yano, T Ezaz, O Moreira-Filho, T Hatanaka, V Trifonov, T Liehr, AB Hamid Al-Rikabi, P Ráb, H Pains, M de Bello Cioffi.
Tracking the evolutionary pathway of sex chromosomes among fishes: characterizing the unique XX/XY1Y2 system in Hoplias malabaricus (Teleostei, Characiformes).
Chromosoma 2018, 127:115-128.  		3.530 EVO
644
 		F Moassass, A Wafa, T Liehr, A Al-Ablog, W Al-Achkar.
Down syndrome associated childhood myeloid leukemia with yet unreported acquired chromosomal abnormalities and a new potential adverse marker: dup(1)(q25q44).
Mol Cytogenet 2018, 11:22. 		1.331 TCG
643
 		T Liehr, I Schreyer, A Kuechler, E Manolakos, S Singer, A Dufke, K Wilhelm, T Jančušková, R Čmejla, MAK Othman, AH Al-Rikabi, K Mrasek, M Ziegler, S Kankel, K Kreskowski, A Weise.
Parental origin of deletions and duplications – about the necessity to check for cryptic inversions.
Mol Cytogenet 2018, 11:20.
 		1.331 CG
642
 		I Papoulidis, A Vetro, V Paspaliaris, M Ziegler, K Kreskowski, G Daskalakis, V Papadopoulos, T Dagklis, T Liehr, L Thomaidis, E Manolakos.
A girl with 10 Mb distal Xp deletion arising from maternal pericentric inversion: Clinical data and molecular characterization.
Curr Genomics 2018, 19:240-246.  		2.174 CG
641
 		W Sangpakdee, A Tanomtong, A Chaveerach, K Pinthong, V Trifonov, K Loth, C Hensel, T Liehr, A Weise, X Fan.
Molecular cytogenetic analysis of one African and five Asian macaque species reveals identical karyotypes as in mandrill.
Curr Genomics 2018, 19:207-215.
 		2.174 EVO
640
 		ABH Al-Rikabi, S Pekova, X Fan, T Jančušková, T Liehr.
Small supernumerary marker chromosome may provide information on dosage-insensitive pericentric regions in human.
Curr Genomics 2018, 19:192-199. 		2.174 sSMC
639
 		T Liehr, N Acquarola, K Pyle, S St-Pierre, M Rinholm, O Bar, K Wilhelm, I Schreyer.
Next generation phenotyping in Emanuel and Pallister Killian Syndrome using computer-aided facial dysmorphology analysis of 2D photos.
Clin Genet 2018, 93:378-381.		 4.104 sSMC
638
 		M Moysés-Oliveira, G Giannuzzi, RJ Fish, JA Rosenfeld, F Petit, M de Fatima Soares, L Domenici Kulikowski, A Di Battista, M Zamariolli, F Xia, T Liehr, N Kosyakova, G Carvalheira, M Parker, EG Seaby, S Ennis, RD Gilbert, T Hagelstrom, DG Basel, J Andrieux, T Stumpp, F Antunes, GJ Pereira, M Neerman-Arbez, VA Meloni, M Drummond-Borg, MI Melaragno, A Reymond.
Inactivation of AMMECR1 is associated with growth, bone and heart alterations.
Hum Mut 2018, 39:281-291.
 		4.453 CG
637
 		RR Capela de Matos, MAK Othman, GM Ferreira, ES Costa, JB Melo, IM Carreira, MT de Souza, BA Lopes, M Emerenciano, MGP Land, T Liehr, RC Ribeiro, MLM Silva.
Molecular approaches identify a cryptic MECOM rearrangement in a child with a rapidly progressive myeloid neoplasm.
Cancer Genet 2018, 221:25-30. 		2.183 TCG
636
 		A Wafa, B Ali, A Aljapawe, T Liehr, S ALmedani, W Al Achkar.
Unreported combination of rearrangements in a childhood B-cell acute lymphoblastic leukemia case: Coexistence of translocation t(8;14) and monoallelic loss of tumor suppressor gene TP53.
Gene Reports 2018, 10:66-70.  		n.a. TCG
635
 		MT De Souza, G Vera-Lozada, M Othman, TJ Marques-Salles, LW Pinto, MM da Rocha, S Rouxinol, T Liehr, RC Ribeiro, R Hassan, MLM Silva.
Molecular and cytogenetic studies in a child with Burkitt lymphoma and ataxia-telangiectasia syndrome harboring MYC overexpression and partial trisomy 8.
Ann Lab Med 2018, 38:63-66. 		2.635 TCG
70% of publications of Institute of Human Genetics Jena in the actual year


2017
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
634
 		T Liehr.
What about the real costs of next generation sequencing (NGS) in human genetic diagnostics? http://atlasofscience.org/what-about-the-real-costs-of-next-generation-sequencing-ngs-in-human-genetic-diagnostics/ 		n.a.
 		M
633
 		T Liehr, IM Carreira.
PWG: Marker chromosomes.
 ECA newsletter 2017, 40:9.		 n.a. sSMC
632
 		T Liehr.
What about noninvasive prenatal testing (NIPT) from ‘cell-free fetal DNA’ (cffDNA)?
http://atlasofscience.org/what-about-noninvasive-prenatal-testing-nipt-from-cell-free-fetal-dna-cffdna/		 n.a. PRE
M
631
 		T Liehr.
Human cells can count their chromosomes – but how do they do?
http://atlasofscience.org/human-cells-can-count-their-chromosomes-but-how-do-they-do/#more-19201		 n.a. INT
630
 		T Liehr, IM Carreira.
PWG: Marker chromosomes.
ECA newsletter 2017, 39:27.		 n.a. sSMC
629
 		T Liehr.
How to characterize best the genetic content of small supernumerary marker chromosomes.
http://atlasofscience.org/how-to-characterize-best-the-genetic-content-of-small-supernumerary-marker-chromosomes/		 n.a. sSMC
628
 		T Liehr.
Chronic lymphocytic leukemia (CLL) diagnostics better to do in cultivated than native cells.
http://atlasofscience.org/chronic-lymphocytic-leukemia-cll-diagnostics-better-to-do-in-cultivated-than-native-cells/		 n.a. TCG
627
 		A Wafa, S ALmedani, T Liehr, F Moassass, W Al-Achkar.
Successful management of three pregnancies under Imatinib treatment in a chronic myeloid leukemia patient: a case report and review of the literature.
J Genetics Genomes 2017, 1:111.		 n.a. TCG
626
 		IR Tkach, NL Huleyuk, DV Zastavna, A Weise, T Liehr, E Ciszkowicz, M Tyrka.
Chromosomal aberrations in spontaneously aborted products of conception from Ukraine.
Biopolymers Cell 2017, 33:424-433.		 n.a. PRE
CG
625
 		T Liehr.
Expert knowledge on human genetic counselling and chromosomics are necessary for sound genetic laboratory diagnostics.
Mol Exp Biol Med 2017, 1:1-3.
n.a. M
624
 		A Kurtovic-Kozaric, L Mehinovic, H Komic, M Kozaric, A Husic-Selimovic, M Ziegler, T Liehr.
Human cytogenetics case report: Yet unreported heteromorphic variant in chromosome 17.
 J Genetics Genomes 2017, 1:101.
 		4.066 HET
623
 		T Liehr, K Mrasek, E Klein, A Weise.
Modern high throughput approaches are not meant to replace ‘old fashioned’ but robust techniques.
J Genetics Genomes 2017, 1:e101.
 		4.066 M
622
 		H Sheth, S Tewari, K Shah, T Liehr, J Trivedi, M Pandya, JJ Sheth, F Sheth.
Prenatal detection of cryptic genomic rearrangement: role of detailed family history, pedigree analysis and advanced genomic technologies.
Int J Preg Child Birth 2017, 3:00071.		 n.a. CG
621
 		DR Ney Garcia, MT de Souza, AF de Figueiredo, MGP Land, MAK Othman, K Rittscher, E Abdelhay, RR Capela de Matos, C Meyer, R Marschalek, T Liehr, RC Ribeiro, MLM Silva.
Molecular characterization of KMT2A-fusion partner genes in 13 cases of pediatric leukemia with a complex or cryptic karyotype.
Hem Oncol 2017, 35:760-768
3.193 TCG
620
 		Z Papadopoulou, I Papoulidis, S Sifaki, G Markopoulos, A Vetro, A-M Vlaikou, M Ziegler, T Liehr, L Thomaidis, O Zuffardi, M Syrrou, K George, E Manolakos.
Partial monosomy 8p and trisomy 16q in two children with developmental delay detected with aCGH.
Mol Med Rep 2017, 16:8808-8818.
1.922 CG
619
 		PC Carvalho, E Aguiar de Oliveira, LAC Bertollo, CF Yano, C Oliveira, E Decru, OI Jegede, T Hatanaka, T Liehr, ABH Al-Rikabi, M de Bello Cioffi.
Insights into relationship between African and Neotropical fish groups: First chromosomal analysis in Hepsetidae (Actinopterygii, Characiformes).
Frontiers in Genetics, section Evolutionary and Population Genetics 2017, 8:203.
 		4.151 EVO
618
 		T Liehr, O Buleu, T Karamysheva, A Bugrov, N Rubtsov.
New insights into Phasmatodea chromosomes.
Genes (Basel) 2017, 8:E327.		 3.191 EVO
617
 		K Guja, T Liehr, M Rincic, N Kosyakova, SS Hussein Azawi.
Molecular cytogenetic characterization identified the murine B-Cell lymphoma cell line A-20 as a model for sporadic Burkitt's lymphoma.
J Histochem Cytochem 2017, 65:669-677.
 		2.816 TCG
616
 		T Liehr.
The first internet page on chromosomal heteromorphisms (HMs).
ECA newsletter 2017, 40:32-33.
n.a. HET
615
 		TV Karamysheva, AA Torgasheva, YR Yefremov, AG Bogomolov, T Liehr, PM Borodin, NB Rubtsov.
Spatial organization of fibroblast and spermatocyte nuclei with different B chromosome content in Korean field mouse Apodemus peninsulae (Rodentia, Muridae).
Genome 2017, 60:815-824.
 		1.892 EVO
614
 		J Karimzad Hagh, T Liehr, H Ghaedi, MM Mossalaeie, S Alimohammadi , F Inanloo Hajiloo , Z Moeini , S Sarabi , D Zare-Abdollahi.
Prenatal diagnosis of mosaic tetrasomy 18p in a case without sonographic abnormalities.
Int J Mol Cell Med (IJMCM) 2017, 6:61-65.
 		n.a. sSMC
613
 		M Donat, A Louis, K Kreskowski, M Ziegler, A Weise, I Schreyer, T Liehr.
X-autosome and X-Y translocations in female carriers: X-chromosome inactivation easily detectable by 5-ethynyl-2-deoxyuridine (EdU).
Balk J Med Genet 2017, 20:87-90.
 		0.306 M
612
 		DC de Souza, AF de Figueiredo, DR Ney Garcia, ES da Costa, MAK Othman, T Liehr, E Abdelhay, MLM Silva, T de Souza Fernandez.
A unique set of complex chromosomal abnormalities in an infant with myeloid leukemia associated with Down syndrome.
Mol Cytogenet 2017, 10:35.
 		1.167 TCG
611
 		R Capela de Matos, D Ney Garcia, E Batista, M Othman, M de Souza, E Carboni, G Ferreira, T Liehr, R Ribeiro, MLM Silva.
GAS6 oncogene and reverse MLLT3-KMT2A duplications in an infant with acute myeloid leukemia and a novel complex hyperdiploid karyotype: detailed high-resolution molecular cytogenetic studies.
Cytogenet Genome Res 2017, 152:33-37.
 		1.587 TCG
610
 		LA Mendez-Rosado, A Lantigua, J Galarza, ABH Al-Rikabi, M Ziegler, T Liehr.
Unusual de novo partial trisomy 17p12p11.2 due to unbalanced insertion into 5p13.1 in a severely affected boy.
J Pediatr Genet 2017, 6:165-168.
 		n.a. CG
609
 		EG Coci, A Auhuber, A Langenbach, K Mrasek, J Riedel, A Leenen, T Lücke, T Liehr.
Novel unbalanced translocations affecting the long arms of chromosome 10 and 22 causes complex syndromes with very severe neuro-developmental delay, speech impairment, autistic behavior and epilepsy.
Cytogenet Genome Res 2017, 151:171-178.
 		1.587 CG
608
 		T Liehr.
Thorough discussion of cancer research – thoughts against the main stream.
Europ J Hum Genet 2017, 25:902-903.
3.636 TCG
607
 		A Wafa, S Almedani, T Liehr, M Ziegler, A Aljapawe, W Al Achkar.
Complex karyotype involving six chromosomes, with one dicentric and three yet unreported acquired chromosomal aberrations in a case of splenic marginal zone lymphoma.
Gene Rep 2017, 8:79-83.
n.a. TCG
606
 		T Liehr, A Weise, I Schreyer.
Humangenetische Diagnostik – muss es immer NGS sein?
BIOspektrum 2017, 03/17:350-351.
 		n.a. M
605
 		MA Merlo, R Iziga, S Portela, I Cross, N Kosyakova, T Liehr, M Manchado, L Rebordinos.
Analysis of the histone cluster in Senegalese sole (Solea senegalensis): evidence for a divergent evolution of two canonical histone clusters.
Genome 2017, 60:441-453.
1.892 EVO
604
 		W Al-Achkar, F Moassass, R Aroutiounian, T Harutyunyan, T Liehr, A Wafa.
Effect of Glutathione S-transferase mu 1 (GSTM1) gene polymorphism on chronic myeloid leukemia risk and Imatinib treatment response.
Metagene 2017, 12:113-117.
n.a. TCG
603
 		CF Yano, LA Bertollo, L Rebordinos, MA Merlo, T Liehr, S Portela-Bens, MB Cioffi.
Evolutionary dynamics of rDNAs and U2 small nuclear DNAs in Triportheus (Characiformes, Triportheidae): High variability and particular syntenic organization.
Zebrafish 2017, 14:146-154.
 		1.733 EVO
602
 		T Liehr, IM Carreira, D Aktas, E Bakker, M Rodríguez de Alba, DA Coviello, L Florentin, H Scheffer, M Rincic; the Clinical Laboratory Geneticists Professional Branch Board, European Board of Medical Genetics, Vienna, Austria.
European registration process for Clinical Laboratory Geneticists in genetic healthcare.
Europ J Hum Genet 2017, 25:515-519.
 		3.636 other
601
 		A Wafa, M As’sad, T Liehr, A Aljapawe, W Al-Achkar.
Childhood pre-B-acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6 and 13.
J Med Case Rep 2017, 11:94.
 		n.a. TCG
600
 		S Portela-Bens, MA Merlo, ME Rodríguez, I Cross, M Manchado, N Kosyakova, T Liehr, L Rebordinos.
Integrated gene mapping and synteny studies give insights into the evolution of a sex proto-chromosome in Solea senegalensis.
Chromosoma 2017; 126:261-277.		 4.021 EVO
599
 		M Volleth, N Truong Son, Y Wu, Y Li, W Yu, L-K Lin, S Arai, V Trifonov, T Liehr, M Harada.
Comparative chromosomal studies in Rhinolophus formosae and R. luctus from China and Vietnam: elevation of R. l. lanosus to species rank.
Acta Chiropt 2017, 19:41-50.
 		1.097 EVO
598
 		T Liehr, A Lauten, U Schneider, E Schleussner, A Weise.
Noninvasive prenatal testing (NIPT) – when is it advantageous to apply?
Biomed Hub 2017, 2:458432.
 		n.a. M
PRE
597
 		T Thooptianrat, A Chaveerach, R Sudmoon, T Tanee, T Liehr, N Babayan.
Screening of phytochemicals and toxicity of medicinal plants, Dillenia species, reveals potential natural product resources.
J Food Biochem 2017, 41:e12363.
 		1.552 EVO
596
 		ML Borges, RR Capela de Matos, BD Amaral, EM Soares-Ventura, EP Leite, MO Silva, MT Cornélio, ML Silva, T Liehr, T Marques-Salles.
Molecular cytogenetic approach to characterize novel and cryptic chromosome abnormalities in childhood myeloid malignances of Fanconi anemia.
J Ped Hematol Oncol 2017, 39:e85-e91.		 1.060 TCG
595
 		T Liehr.
“Classical cytogenetics” is not equal to “banding cytogenetics”.
Mol Cytogenet 2017, 10:3.
 		1.167 M
594
 		R Hochstenbach, M Poot, T Liehr.
Mechanisms of origin and clinical effects of multiple small supernumerary marker chromosomes, each derived from a different chromosome.
OBM Genetics 2017, 1:002.
 		n.a. sSMC
593
 		CF Yano, LAC Bertollo, T Ezaz, V Trifonov, A Sember, T Liehr, MB Cioffi.
Highly conserved Z and molecularly diverged W chromosomes in the fish genus Triportheus (Characiformes, Triportheidae).
Heredity 2017, 118:276-283.
3.872 EVO
592
 		M Fischer, N Kosyakova, T Liehr, P Dobrowolski.
Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice.
Mamm Genome 2017, 28: 31-37 .
 		2.687 EVO
591
 		F Santiago, S Lima, T Pinheiro, RT Silvestre, UB Otero, MM Tabalipa, N Kosyakova, MH Ornellas, T Liehr, G Alves.
Benzene poisoning, clinical and blood abnormalities in two Brazilian female gas station attendants: two case reports.
BMC Res Notes 2017, 10:52.		 n.a. TCG
590
 		E Kubicova, V Trifonov, F Borovecki, T Liehr, M Rincic, N Kosyakova, SS Hussein.
First molecular cytogenetic characterization of murine malignant mesothelioma cell line AE17 and in silico translation to the human genome.
Curr Bioinform 2017, 12:11-18.		 0.540 TCG
63% of publications of Institute of Human Genetics Jena in the actual year

2016
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
589
 		AC Malinverni, ME Colovati, AB Perez, TP Caneloi, HR Oliveira Jr, N Kosyakova, T Liehr, AB Hamid, MI Melaragno.
Unusual duplication in the pericentric region of chromosome 9 in a patient with phenotypic alterations.
Cytogenet Genome Res 2016, 150:100-105.
 		1.354 CG
HET
588
 		A Wafa, F Moassass, T Liehr, S Bhatt, A Aljapawe, W Al Achkar.
A high complex karyotype involving eleven chromosomes including three novel chromosomal aberrations and monoallelic loss of TP53 in case of follicular lymphoma transformed into B-cell lymphoblastic leukemia.
Mol Cytogenet 2016, 9:91. 		1.455 TCG
587
 		FJ Sheth, L Naznin, T Liehr, JJ Sheth.
FISH – The best technique in characterization of prenatally detected small supernumerary marker chromosomes (sSMC).
Int J Pregn & Chi Birth 2016, 1:00005.		 n.a. sSMC
586
 		A Wafa, F Moassass, T Liehr, A Aljapawe, W Al Achkar.
Partial trisomy 1q21-qter and partial monosomy 7q21-qter due to a derivative chromosome 7 in myelodysplastic syndrome associated with squamous cell carcinoma: Case report.
Case Rep Clin Med 2016, 5:518-527.		 n.a. TCG
585
 		O Kadioglu, J Cao, N Kosyakova, K Mrasek, T Liehr, T Efferth.
Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unraveling the full complexity of multifactorial multidrug resistance.
Sci Rep 2016, 6:36754. 		4.259 TCG
584
 		T Liehr.
Editorial: BIRC3 as a yet underestimated prognostic marker of malignancies?
Translat Cancer Res 2016, 5:3. doi: 10.21037/tcr.2016.09.29.
 		1.167 TCG
583
 		J Filipović, G Joksić, D Vujić, I Joksić, K Mrasek, A Weise, T Liehr.
First molecular-cytogenetic characterization of Fanconi anemia fragile sites in primary lymphocytes of FA-D2 patients in different stages of the disease.
Mol Cytogenet 2016, 9:70.
 		1.455 TCG
582
 		R Joshi, P Garg, N Zaitlen, T Lappalainen, CT Watson, N Azam, D Ho, SE Antonarakis, HG Brunner, K Buiting, SW Cheung, B Coffee, T Eggermann, D Francis, JP Geraedts, G Gimelli, SG Jacobson, C Le Caignec, N de Leeuw, T Liehr, DJ Mackay, SB Montgomery, AT Pagnamenta, P Papenhausen, DO Robinson, C Ruivenkamp, C Schwartz, B Steiner, DA Stevenson, U Surti, T Wassink, AJ Sharp.
DNA methylation profiling of uniparental disomy subjects provides a map of parental epigenetic bias in the human genome.
Am J Hum Genet 2016, 99:555-566.
9.025 UPD
581
 		V Bugarski Stanojević, G Stamenković, J Blagojević, T Liehr, N Kosyakova, M Rajičić, M Vujošević.
Exploring supernumeraries - a new marker for screening of B-chromosomes presence in the yellow necked mouse Apodemus flavicollis.
PLoS One 2016, 11:e0160946.
 		2.806 EVO
580
 		H Fryssira, E Tsoutsou, S Psoni, S Amenta, T Liehr, E Anastasakis, C Skentou, A Ntouflia, I Papoulidis, E Manolakos, N Chaliasos.
Partial monosomy14q involving FOXG1 and NOVA1 in an infant with microcephaly, seizures and severe developmental delay.
Mol Cytogenet 2016, 9:55.
1.455 CG
579
 		M Rinčić, IY Iourov, T Liehr.
Thoughts about SLC16A2, TSIX and XIST gene like sites in the human genome and a potential role in cellular chromosome counting.
Mol Cytogenet 2016, 9:56.
1.455 INT
578
 		W Sangpakdee, S Phimphan, T Liehr, X Fan, K Pinthong, I Patawang, A Tanomtong.
Characterization of chromosomal rearrangements in pileated gibbon (Hylobates pileatus) using multiplex-FISH technique.
The Nucleus 2016; 59:131-135.  		n.a. EVO
577
 		A Wafa, F Moassass, T Liehr, A Al-Ablog, W Al-Achkar.
Acute promyelocytic leukemia with the translocation t(15;17)(q22;q21) associated with t(1;2)(q42~43;q11.2~12): a case report.
J Med Case Rep 2016, 10:203.
n.a. TCG
576
 		MH Ornellas, MdF Silva, C Solza, SBSdL Goncalves, L Silva de Almeida, JdP Ayres-Silva, TL Seixa, EF Bastos, T Liehr, G Alves.
Myelodysplastic syndrome without ring sideroblasts and with Janus kinase 2 gene mutation: An unusual case report.
Mol Clin Oncol 2016, 5:227-230.
n.a. TCG
575
 		E Alhourani, R Aroutiounian, T Harutyunyan, A Glaser, C Schlie, B Pohle, T Liehr.
Interphase molecular cytogenetic detection rates of chronic lymphocytic leukemia specific aberrations are higher in cultivated cells than in blood or bone marrow smears.
J Histochem Cytochem 2016, 64:495-501.
2.511 TCG
574
 		A Wafa, M Assad, T Liehr, A Aljapawe, W Al Achkar.
A new complex karyotype in a unique de novo myelodysplastic syndrome case involving ten chromosomes and monoallelic loss of TP53.
Gene Rep 2016, 4:208-212.
n.a. TCG
573
 		G Hovhannisyan, R Aroutiounian, N Babayan, T Harutyunyan, T Liehr.
Comparative analysis of individual chromosome involvement in micronuclei induced by mitomycin C and bleomycin in human leukocytes.
Mol Cytogenet 2016, 9:49.
 		1.455 TCG
572
 		B Wannenmacher, D Mitter, F Kießling, T Liehr, A Weise, M Siekmeyer, W Kiess.
A 33-year-old male patient with paternal derived duplication of 14q11.2-14q22.1~22.3: clinical course, phenotypic and genotypic findings.
J Pediatr Endocrinol Metab 2016, 29:611-616.
1.233 CG
571
 		S Amasdl, A Natiq, SC Elalaoui, A Sbiti, T Liehr, A Sefiani.
Insulin-like growth factor type 1 deficiency in a Moroccan patient with de novo inverted duplication 9p24p12 and developmental delay: a case report.
J Med Case Rep 2016, 10:122.		 n.a. CG
570
 		CF Yano, LA Bertollo, T Liehr, WP Troy, MB Cioffi.
W chromosome dynamics in Triportheus species (Characiformes, Triportheidae) - an ongoing process narrated by repetitive sequences.
J Hered 2016, 2016:342-348.
2.432 EVO
569
 		T Liehr.
Benign and pathological gain or loss of genetic material - about microscopic and submicroscopic copy number variations (CNVs) in human genetics.
Tsitologiya 2016, 58:476-477.
n.a. HET
568
 		A Weise, S Bhatt, K Piaszinski, N Kosyakova, X Fan, A Altendorf-Hofmann, A Tanomtong, A Chaveerach, M Bello de Cioffi, E de Oliveira, J-U Walther, T Liehr, JP Chaudhuri.
Chromosomes in a genome-wise order: evidence for metaphase architecture.
Mol Cytogenet 2016, 9:36.		 1.455 INT
567
 		E Alhourani, MAK Othman, JB Melo, IM Carreira, B Grygalewicz, D Vujić, Z Zecević, G Joksić, A Glaser, B Pohle, C Schlie, S Hauke, T Liehr.
BIRC3 alterations in chronic and B-cell acute lymphocytic leukemia patients.
Oncol Lett 2016, 11:3240-3246.
1.390 TCG
566
 		M Rincic, M Rados, Z Krsnik, K Gotovac, F Borovecki, T Liehr, L Brecevic.
Complex intrachromosomal rearrangement in 1q leading to 1q32.2 microdeletion: a potential role of SRGAP2 in the gyrification of cerebral cortex.
Mol Cytogenet 2016, 9:19.
1.455 CG
565
 		A Zlotina, T Kulikova, N Kosyakova, T Liehr, A Krasikova.
Microdissection of lampbrush chromosomes as an approach for generation of locus-specific FISH-probes and samples for high-throughput sequencing.
BMC Genomics 2016, 17: 126.
3.729 INT
M
EVO
564
 		W Sangpakdee, A Tanomtong, X Fan, K Pinthong, A Weise, T Liehr.
Application of multicolor banding combined with heterochromatic and locus-specific probes identify evolutionary conserved breakpoints in Hylobates pileatus.
Mol Cytogenet 2016, 9:17.
1.455 EVO
563
 		MAK Othman, B Grygalewicz, B Pienkowska-Grela, J Rygier, A Ejduk, M Rincic, JB Melo, IM Carreira, B Meyer, T Liehr.
A new IGH@ gene rearrangement associated with CDKN2A/B deletion in a young adult B-cell acute lymphoblastic leukemia (B-ALL).
Oncol Lett 2016, 11:2117-2122.		 1.390 TCG
562
 		T Liehr, H Heng, Y Yurov, A Meloni-Ehrig, I Iourov.
Reviewer acknowledgement 2016.
Mol Cytogenet 2016, 9:24.
 		1.455 other
561
 		EG Coci, U Koehler, T Liehr, A Stelzner, C Fink, H Langen, J Riedel.
CANPMR syndrome and chromosome 1p32-p31 deletion syndrome coexist in two related individuals affected by simultaneous haplo-insufficiency of CAMTA1 and NIFA genes.
Mol Cytogenet 2016, 9:10.
 		1.455 CG
560
 		T Liehr.
Cytogenetically visible copy number variations (CG-CNVs) in banding and molecular cytogenetics of human; about heteromorphisms and euchromatic variants.
Mol Cytogenet 2016, 9:5.
1.455 HET
559
 		S Amasdl, A Natiq, A Sbiti, M Zerkaoui, J Lyahyai, T Liehr, S Amzazi, A Sefiani.
20p12.3 deletion is rare cause of syndromic cleft palate: case report and review of literature.
BMC Research Notes 2016, 9:5.
n.a. CG
58% of publications of Institute of Human Genetics Jena in the actual year


2015
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
558
 		T Liehr, IM Carreira.
PWG: Marker chromosomes.
 ECA newsletter 2015, 36:5-. 		n.a. sSMC
557
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2015, 35:31. 		n.a. sSMC
556
 		IE Gooma, S Bhatt, T Liehr, M Glei, TA El-Tayeb.
Comparative study of Ag and Co / Ag nanoparticles mediated by photothermal therapy of cancer.
Egypt J Zool 2015, 63:99-117.
 		n.a. TCG
555
 		M Kontodiou, G Daskalakis, A Vetro, V Paspaliaris, G Papaioannou, T Dagklis, I Tsakiridis, M Ziegler, T Liehr, L Thomaidis, I Papoulidis, E Manolakos.
Complex rearrangement involving three chromosomes, four breakpoints and a 2.7 Mb deletion on 18q segment observed in a girl with mild learning difficulties.
Cytogenet Genome Res 2015, 147:118-123. 		1.638 CG
554
 		AA Darouich, T Liehr, A Weise, D Schlembach, E Schleußner, M Kiehntopf, I Schreyer.
Alpha-fetoprotein and its value for predicting pregnancy outcomes – a re-evaluation.
J Prenat Med 2015, 9:18-23. 		n.a. PRE
553
 		R Hochstenbach, B Nowakowska, M Volleth, A Ummels, A Kutkowska-Kamierczak, E Obersztyn, K Ziemkiewicz, C Gerloff, D Schanze, M Zenker, P Muschke, I Schanze, M Poot, T Liehr.
Multiple small supernumerary marker chromosomes resulting from maternal meiosis I or II errors.
Mol Syndromol 2015, 6:210-221. 		n.a. sSMC
552
 		A Wafa, S Almedani, T Liehr, W Al-Achkar.
Masked inv dup(22)(q11.23), tetrasomy 8 and trisomy 19 in a blast crisis-chronic myeloid leukemia after interrupted Imatinib-treatment.
Mol Cytogenet 2015, 8:98. 		1.506 TCG
551
 		M Manvelyan, I Simonyan, G Hovhannisyan, R Aroutiounian, AB Hamid, T Liehr.
A new case of a complex small supernumerary marker chromosome, a der(9)t(7;9)(p22;q22) due to a maternal balanced rearrangement.
J Ped Genet 2015, 4:199-200.   		n.a.   sSMC
550
 		E Alhourani, M Rincic, JB Melo, IM Carreira, A Glaser, B Pohle, C Schlie, T Liehr.
Isochromosome 17q in chronic lymphocytic leukemia.
Leuk Res Treatment 2015, 2015:489592.  		n.a.   TCG
549
 		K Reichwald, A Petzold, P Koch, BR Downie, N Hartmann, S Pietsch, M Baumgart, D Chalopin, M Felder, M Bens, A Sahm, K Szafranski, S Taudien, M Groth, I Arisi, A Weise, SS Bhatt, V Sharma, JM Kraus, F Schmid, S Priebe, T Liehr, M Görlach, ME Than, M Hiller, HA Kestler, J-N Volff, M Schartl, A Cellerino, C Englert, M Platzer.
Insights into sex chromosome evolution and aging from the genome of a short-lived fish.
Cell 2015, 163:1527-1538.  		28.710 EVO
548
 		X Fan, W Supiwong, A Weise, K Mrasek, N Kosyakova, A Tanomtong, K Pinthong, VA Trifonov, M de Bello Cioffi, P Grothmann, T Liehr, EHC de Oliveira.
Comprehensive characterization of evolutionary conserved breakpoints in four New World Monkey karyotypes compared to Chlorocebus aethiops and Homo sapiens.
Helyion 2015, 1: e00042.
 n.a. EVO
547
 		M Moysés-Oliveira, RS Guilherme, VA Meloni, A Di Battista, CB de Mello, S Bragagnolo, D Moretti-Ferreira, N Kosyakova, T Liehr, GM Carvalheira, MI Melaragno MI.
X-linked intellectual disability related genes disrupted by balanced X-autosome translocations.
Am J Med Genet B Neuropsychiatr Genet 2015, 168:669-677. 		3.391 CG
546
 		M Rath, J Najm, H Sirb, K Kentouche, A Dufke, S Pauli, K Hackmann, T Liehr, CA Hübner, U Felbor, Kompetenznetzwerk Hämorrhagische Diathesen Ost (KHDO).
Large deletions play a minor but essential role in congenital coagulation factor VII and X deficiencies.
Hämostaseologie 2015, 35:S36-S42.
 		1.547 CG
545
 		MAM Abo-Zeid, T Liehr, M Glei, AM Gamal-Eldeen, M Zawrah, M Ali.
Detection of cyto- and genotoxicity of rod-shaped gold nanoparticles in human blood lymphocytes using comet-FISH.
Cytologia 2015, 80:173-181. 		0.227 TCG
544
 		N Armanet, L Tosca, S Brisset, T Liehr, G Tachdjian.
Small supernumerary marker chromosomes in human infertility.
Cytogenet Genome Res 2015, 146:100-108.
 		1.638 sSMC
543
 		S Winkler, M Hempel, S Brückner, F Mallek, A Weise, T Liehr, HM Tautenhahn, M Bartels, B Christ.
Mouse white adipose tissue-derived mesenchymal stem cells gain pericentral and periportal hepatocyte features after differentiation in vitro, which are preserved in vivo after hepatic transplantation.
Acta Physiol 2015, 215:89-104.  		4.066 CG
542
 		H Jafari-Ghahfarokhi, M Moradi-Chaleshtori, T Liehr, M Hashemzadeh-Chaleshtori, H Teimori, P Ghasemi-Dehkordi.
Small supernumerary marker chromosomes and their correlation with specific syndromes.
Adv Biomed Res 2015, 4:140. 		n.a. sSMC
541
 		AF de Figueiredo, RR Capela de Matos, MA Othman, T Liehr, ES da Costa, MG Land, RC Ribeiro, E Abdelhay, ML Silva.
Molecular cytogenetic studies characterizing a novel complex karyotype with an uncommon 5q22 deletion in childhood acute myeloid leukemia.
Mol Cytogenet 2015, 8:62. 		1.506 TCG
540
 		 A Wafa, M Asa‘ad, A Ikhtiar, T Liehr, W Al-Achkar.
Deletion 9p23 to 9p11.1 as sole additional abnormality in a Philadelphia positive chronic myeloid leukemia in blast crisis: a rare event.
Mol Cytogenet 2015, 8:59. 		1.506 TCG
539
 		E Aguiar de Oliveira, LAC Bertollo, CF Yano, T Liehr, M de Bello Cioffi.
Comparative cytogenetics in the genus Hoplias (Characiformes, Erythrinidae) highlights contrasting karyotype evolution among congeneric species.
Mol Cytogenet 2015, 8:56.  		1.506 EVO
538
 		F Sheth, T Liehr, K Shah, J Sheth.
Prader-Willi syndrome - type 1 deletion, a consequence of an unbalanced translocation of chromosomes 13 and 15, easily to be mixed up with a Robertsonian translocation.
Mol Cytogenet 2015, 8:52.  		1.506 CG
537
 		MAK Othman, JB Melo, IM Carreira, M Rincic, A Glaser, B Grygalewicz, B Gruhn, K Wilhelm, K Rittscher, B Meyer, MLM Silva, T de Jesus Marques Salles, T Liehr.
High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia.
Mol Cytogenet 2015, 8:45. 		1.506 TCG
536
 		RR Capela de Matos, AF De Figueiredo, T Liehr, E Alhourani, MT De Souza, E Abdelhay, RC Ribeiro, MLM Silva.
A novel three-way variant t(8;13;21)(q22;q33;q22) in a child with acute myeloid leukemia FAB AML-M2: contribution of molecular approaches to reveal t(8;21) variants.
Acta Hematol 2015, 134:243-245.  		1.506 TCG
535
 		MAM Abo-Zeid, T Liehr, AM Gamal-Eldeen, M Zawrah, M Ali, MAK Othman.
Potential of rod, sphere and semi-cube shaped gold nanoparticles to induce cytotoxicity and genotoxicity in human blood lymphocytes in vitro.
Eur J Nanomed 2015, 7:63-75 		n.a. TCG
534
 		A Weise, N Kosyakova, M Voigt, N Aust, K Mrasek, S Löhmer, N Rubtsov, T Karamysheva, V Trifonov, D Hardekopf, T Jancuková, S Pekova, K Wilhelm, T Liehr, X Fan.
Comprehensive analyses of white handed gibbon chromosomes enables access to 92 evolutionary conserved breakpoints compared to the human genome.
Cytogenet Genome Res 2015, 145:42-49
1.638 EVO
533
 		DR Ney Garcia, T Liehr, M Emerenciano, C Meyer, R Marschalek, M do Socorro Pombo de Oliveira, RC Ribeiro, MGP Land, ML Macedo Silva.
Molecular studies reveal MLL-MLLT3 gene fusion displaced in a case of childhood acute lymphoblastic leukemia with complex karyotype.
Cancer Genet 2015, 208:143-147 		2.333 TCG
532
 		PG Maass, A Aydin, FC Luft, C Schächterle, A Weise, S Stricker, C Lindschau, M Vaegler, F Qadri, HR Toka, H Schulz, PM Krawitz, J Hecht, I Hollfinger, Y Wefeld-Neuenfeld, E Bartels-Klein, A Mühl, M Kann, H Schuster, D Chitayat, MG Bialer, TF Wienker, J Ott, K Rittscher, T Liehr, J Jordan, G Plessis, J Tank, K Mai, R Naraghi, R Hodge, M Hopp, LO Hattenbach, A Busjahn, A Rauch, F Vandeput, M Gong, F Rüschendorf, N Hübner, H Haller, S Mundlos, N Bilginturan, MA Movsesian, E Klussmann, O Toka, S Bähring.
PDE3A mutations cause autosomal-dominant hypertension with brachydactyly.
Nat Genet 2015, 47:647-653.		 31.616 CG
531
 		SA Romanenko, PL Perelman, VA Trifonov, NA Serdyukova, T Li, B Fu, PC O'Brien, BL Ng, W Nie, T Liehr, R Stanyon, AS Graphodatsky, F Yang.
A first generation comparative chromosome map between guinea pig (Cavia porcellus) and humans.
PLoS One 2015, 10:e0127937.		 3.057 EVO
530
 		S Ledig, S Preisler-Adams, S Morlot, T Liehr, P Wieacker.
Premature ovarian failure caused by a heterozygous missense mutation in POF1B and a reciprocal translocation 46,X,t(X;3)(q21.1;q21.3).
Sex Dev 2015, 9:86-90. 		2.164 CG
529
 		G Kirkpatrick, H Ren, T Liehr, V Chow, S Ma.
Meiotic and sperm aneuploidy studies in three carriers of Robertsonian translocations and small supernumerary marker chromosomes.
Fertil Steril 2015, 103:1162-1169.e7. 		4.426 sSMC
528
 		M Moysés-Oliveira, RD Guilherme, AG Dantas, R Ueta, AB Perez, M Haidar, R Canonaco, VA Meloni, N Kosyakova, T Liehr, GM Carvalheira, MI Melaragno.
Genetic mechanisms leading to primary amenorrhea in balanced X-autosome translocations.
Fertil Steril 2015, 103:1289-1296.e2. 		4.426 CG
527
 		W Al-Achkar, F Moassass, A Al-Ablog, T Liehr, X Fan, A Wafa.
A Syrian couple with chromosomal aberration and MTHFR polymorphism leads to recurrent pregnancy loss and partial trisomy of 5p12-15.3 in the offspring: Case report and review to the literature.
Zhonghua Nan Ke Xue = Nat J Androl 2015, 21:219-224. 		n.a. CG
526
 		MAK Othman, B Grygalewicz, B Pienkowska-Grela, M Rincic, K Rittscher, JB Melo, IM Carreira, B Meyer, W Marzena, T Liehr.
Novel cryptic rearrangements in adult B cell precursor acute lymphoblastic leukemia involving MLL gene.
J Histochem Cytochem 2015, 63:384-390. 		1.953 TCG
525
 		F Sheth, M Rahman, T Liehr, M Desai, B Patel, C Modi, S Trivedi, J Sheth.
Prenatal screening of cytogenetic anomalies – a Western Indian experience.
BMC Preg Childbirth 2015, 15:90.
 		2.180 PRE
CG
524
 		T Harutyunyan, G Hovhannisyan, N Babayan, M Othman, T Liehr, R Aroutiounian.
Influence of aflatoxin B1 on copy number variants in human leukocytes in vitro.
Mol Cytogenet 2015, 8:25.
 		1.506 TCG
523
 		MAK Othman, D Vujić, Z Zecević, M Đurišić, B Slavković, B Meyer, T Liehr.
A cryptic three-way translocation t(10;19;11)(p12.31;q13.31;q23.3) with a derivative Y-chromosome in an infant with acute myeloblastic leukemia (M5b).
Gene 2015, 563:115-119. 		2.319 TCG
522
 		IR Tkach, KO Sosnina, NL Huleyuk, OI Terpylyak, DV Zastavna, A Weise, N Kosyakova, T Liehr.
Contribution of chromosomal abnormalities and genes of the major histocompatibility complex to early pregnancy losses.
Biopolymers and Cell 2015, 31:38-45. 		n.a. PRE
CG
521
 		T Liehr, MA Othman, K Rittscher, E Alhourani.
The current state of molecular cytogenetics in cancer diagnosis.
Expert Rev Mol Diagn 2015, 15: 517-526. 		3.333 TCG
520
 		T Liehr, H Heng, Y Yurov, A Meloni-Ehrig, I Iourov.
Reviewer acknowledgement 2015.
Mol Cytogenet 2015, 8:23. 		1.506 other
519
 		L Brečević, M Rinčić, Ž Krsnik, G Sedmak, AB Hamid, N Kosyakova, I Galić, T Liehr, F Borovečki.
Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma.
Translat Neuroscience 2015, 6:59-86. 		1.012 CG
518
 		IE Gomaa, SA Abdel Gaber, S Bhatt, T Liehr, M Glei, TA El-Tayeb, MH Abdel-Kader.
In vitro cytotoxicity and genotoxicity studies of gold nanoparticles-mediated photo-thermal therapy versus 5-fluorouracil.
J Nanopart Res 2015, 17:102. 		2.101 TCG
517
 		M Kehrer, T Liehr, T Benkert, S Singer, U Grasshoff, K Schaeferhoff, M Bonin, A Weichselbaum.
Interstitial duplication of chromosome region 1q25.1q25.3: Report of a patient with mild cognitive deficits, tall stature and facial dysmorphisms.
Am J Med Genet 2015, 167:653-656. 		2.082 CG
516
 		T Karamysheva, N Kosyakova, N Guediche, T Liehr.
Small supernumerary marker chromosomes and the nuclear architecture of sperm – a study in a fertile and an infertile brother.
Syst Biol Reprod Med 2015, 61:32-36. 		1.204 sSMC
INT
515
 		VS Baranov, TE Ivaschenko, T Liehr, MI Yarmolinskaya.
Systems genetics view of endometriosis – a common complex disorder.
Eur J Obstet Gynecol Reprod Biol 2015, 185:59-65. 		1.662 CG
TCG
514
 		MAK Othman, JB Melo, IM Carreira, M Rincic, E Alhourani, K Wilhelm, B Gruhn, A Glaser, T Liehr.
MLLT10 and IL3 rearrangement together with a complex four-way-translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia.
Oncol Rep 2015, 33:625-630.  		2.486 TCG
513
 		T Sahoo, J-C Wang, MM Elnaggar, P Sanchez-Lara, LP Ross, LW Mahon, K Hafezi, A Deming, L Hinman, Y Bruno, JA Bartley, T Liehr, A Anguiano, M Jones.
Concurrent triplication and uniparental isodisomy: evidence for microhomology-mediated break-induced replication model for genomic rearrangements.
Europ J Hum Genet 2015, 23:61-66. 		4.580 UPD
66% of publications of Institute of Human Genetics Jena in the actual year


2014
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
512
 		T Liehr.
Updates on „EBMG Professional Board for Clinical Laboratory Geneticists“ – Open for applications.
ESHG newsletter 2014, 25: 1-2. 		n.a.
 		other
511
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2014, 33:19. 		n.a. sSMC
510
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2014, 34:26. 		n.a. sSMC
509
 		A Sanubol, A Chaveerach, R Sudmoon, T Tanee, T Liehr.
Verification of selected piper species (Piperaceae) using morphological characters, molecular data, and chemical constituents.
Malay Nat J 2014, 66:60-81. 		n.a. EVO
508
 		X Fan, A Tanomtong, A Chaveerach, K Pinthong, S Pornnarong, W Supiwong, T Liehr, A Weise.
High resolution karyotype of Thai crab-eating macaque (Macaca fascicularis).
Genetika 2014, 46:877-882. 		0.347 EVO
507
 		W Al-Achkar, F Moassass, A Ikhtiar, T Liehr, MAK Othman, A Wafa.
Hyperdiploidy associated with T315I mutation in BCR-ABL kinase domain in an accelerated phase-chronic myeloid leukemia case.
Mol Cytogenet 2014, 7:89. 		2.140 TCG
506
 		A Weise, K Mrasek, T Liehr.
Zytogenetische und molekularzytogenetische Methoden in der Pränataldiagnostik.
Med Genetik 2014, 26:391-397. 		0.131 PRE
M
505
 		W Supiwong, T Liehr, MB Cioffi, A Chaveerach, N Kosyakova, X Fan, T Tanee, A Tanomtong.
Comparative cytogenetic mapping of rRNA genes among naked catfishes: Implications for genomic evolution in the Bagridae family.
Genet Mol Res 2014, 13:9533-9542. 		0.775 EVO
504
 		A Natiq, S Amsdel, T Liehr, K Kreskowski, B Meyer, I Ratbi, S Amzazi, A Sefiani.
11p13 deletion syndrome: first case in Morocco detected by FISH.
J Pediatr Neonatal Care 2014, 1:00048.  		n.a. CG
503
 		A Wafa, A Aljapawe, MAK Othman, T Liehr, E Alhourani, W Al Achkar.
Do novo del(9)(p13) in a childhood T-cell prolymphocytic leukemia as sole abnormality.
Exp Hematol Oncol 2014, 3:28.  		n.a. TCG
502
 		E Alhourani, M Rincic, MAK Othman, B Pohle, C Schlie, A Glaser, T Liehr.
Comprehensive chronic lymphocytic leukemia diagnostics by combined multiplex ligation dependent probe amplification (MLPA) and interphase fluorescence in situ hybridization (iFISH).
Mol Cytogenet 2014, 7:79.  		2.140 TCG
501
 		IY Iourov, SG Vorsanova, T Liehr, YB Yurov.
Mosaike im Gehirn des Menschen.
Med Genetik 2014, 26:242-345.  		0.131 INT
500
 		T Liehr.
Entstehungsmechanismen von Zellmosaiken in der genetischen Diagnostik.
Med Genetik 2014, 26:298-301.  		0.131 CG
499
 		T Liehr.
Bedeutung von Zellmosaiken in der genetischen Diagnostik.
Med Genetik 2014, 26:297.  		0.131 CG
498
 		T Liehr.
Small supernumerary marker chromosomes detected in connection with infertility.
Zhonghua Nan Ke Xue = Nat J Androl 2014, 20:771-780. 		n.a. sSMC
497
 		AV Bispo, P Burégio-Frota, L Oliveira dos Santos, GF Leal, AR Duarte, J Araújo, V Cavalcante da Silva, MT Cartaxo Muniz, T Liehr, N Santos.
Y-chromosome in Turner syndrome: detection of hidden mosaicism and the report of a rare X;Y translocation case.
Reprod Fert Develop 2014, 26:1176-1182. 		2.400 CG
496
 		MAK Othman, M Rincic, JB Melo, IM Carreira, E Alhourani, F Hunstig, A Glaser, T Liehr.
A novel cryptic three-way translocation t(2;9;18)(p23.2;p21.3;q21.33) with deletion of tumor suppressor genes in 9p21.3 and 13q14 in a T-cell acute lymphoblastic leukemia.
Leuk Res Treatment 2014, 2014:35712.3  		n.a. TCG
495
 		L Nazaryan, EG Stefanou, C Hansen, N Kosyakova, M Bak, FH Sharkey, T Mantziou, AD Papanastasiou, V Velissariou, T Liehr, M Syrrou, N Tommerup.
The strength of combined cytogenetic and mate-pair sequencing techniques illustrated by a germline chromothripsis rearrangement involving FOXP2.
Europ J Hum Genet 2014, 22:338-343.  		4.349 CG
494
 		SS Hussein, K Kreskowski, M Ziegler, E Klein, AB Hamid, N Kosyakova, M Volleth, T Liehr, X Fan, K Piaszinski.
Mitotic stability of small supernumerary marker chromosomes depends on their shape and telomeres - a long term in vitro study.
Gene 2014, 552:246-248.  		2.138 sSMC
493
 		W Al-Achkar, A Wafa, MAK Othman, F Moassass, A Aljapawe, T Liehr.
An adult B-cell precursor acute lymphoblastic leukemia with multiple secondary cytogenetic aberrations.
Mol Cytogenet 2014, 7:60.		 2.140 TCG
492
 		J Roediger, W Hessenkemper, S Bartsch, M Manvelyan, SS Huettner, T Liehr, M Esmaeili, S Foller, I Petersen, M-O Grimm, A Baniahmad.
Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway.
Mol Cancer 2014, 13:214.		 4.257 TCG
491
 		Y Sahin, PÖ Kiper, Y Alanay, T Liehr, GE Utine, K Boduroğlu.
Partial monosomy 3q26.33-q27.3 presenting with intellectual disability, facial dysmorphism, and diaphragm eventration: a case report.
Clin Dysmorphol 2014, 23:147-151.		 0.416 CG
490
 		SG Vorsanova, IY Iourov, IA Demidova, AD Kolotii, T Liehr, YB Yurov.
Microdeletion 1p36 syndrome: diagnostic problems and the use of molecular cytogenetics for the solution.
Yakut Medical Journal 2014, 2 47-48 (in Russian). 		n.a. CG
489
 		DC de Souza, AF de Figueiredo, H Mkrtchyan, MA Othman, T Liehr, J Dobbin, ML Silva, E Abdelhay, T de S Fernandez.
A yet unreported der(11)t(6;11)(p21;q21) included in a complex karyotype of a refractory anemia with ring sideroblasts and poor prognosis.
Blood Cells Mol Dis 2014, 53:91-93.
 		2.646 TCG
488
 		M de Souza, R Hassan, T Liehr, T Marques-Salles, AM Boulhosa, E Abdelhay, R Ribeiro, MLM Silva.
Conventional and molecular cytogenetic characterization of Burkitt lymphoma with bone marrow involvement in Brazilian children and adolescents.
Ped Blood Cancer 2014, 61:1422-1426. 		2.386 TCG
487
 		CF Yano, LAC Bertollo, WF Molina, T Liehr, M de Bello Cioffi.
Genomic organization of repetitive DNAs and its implications for male karyotype and the neo-Y chromosome differentiation in Erythrinus erythrinus (Characiformes, Erythrinidae).
Comp Cytogen 2014, 8:139-151.  		1.210 EVO
486
 		DR Ney Garcia, TP Vieira, T Liehr, E Abdelhay, R Binato, F Neves, MT de Souza, RC Ribeiro, MLM Silva.
Cryptic t(19;19)(p13.3;q13.2), involving the TCF3/E2A gene, detected and described by molecular cytogenetics in a patient with childhood B-cell progenitor acute lymphoblastic leukemia.
Atlas Genet Cytogenet Oncol Haematol 2014, 18:217-221. 		n.a. TCG
485
 		K Varvagiannis, I Papoulidis, T Koromila, K Kefalas, M Ziegler, T Liehr, MB Petersen, Y Gyftodimou, E Manolakos.
De novo 393kb microdeletion of 7p11.2 characterized by aCGH in a boy with psychomotor retardation and dysmorphic features.
Meta Gene 2014, 2:274-282.  		n.a. CG
484
 		AM Vlaikou, E Manolakos, D Noutsopoulos, G Markopoulos, T Liehr, A Vetro, M Ziegler, A Weise, K Kreskowski, I Papoulidis, L Thomaidis, M Syrrou.
An interstitial 4q31.21q31.22 microdeletion associated with developmental delay: Case report and literature review.
Cytogenet Genome Res 2014, 142:227-238.
1.561 CG
483
 		A Natiq, SC Elalauoi, T Liehr, S Amzazi, A Sefiani.
Characterization of a rare short arm heteromorphism of chromosome 22 in a girl with down-syndrome like facies.
Ind J Hum Genet 2014, 20:89-91.  		n.a. HET
482
 		S Sifakis, M Eleftheriades, D Kappou, R Murru, A Konstantinidou, S Orru, M Ziegler, T Liehr, E Manolakos, I Papoulidis.
Prenatal diagnosis of proximal partial trisomy 1q confirmed by comparative genomic hybridization array: molecular cytogenetic analysis, fetal pathology and review of the literature.
Birth Defects Research Part A: Clinical and Molecular Teratology 2014, 100:284-293.  		2.089 CG
481
 		H Spittel, F Kubek, K Kreskowski, M Ziegler, E Klein, AB Hamid, N Kosyakova, G Radhakrishnan, A Junge, P Kozlowski, B Schulze, T Martin, D Huhle, K Mehnert, L Rodríguez, MA Ergun, C Sarri, M Militaru, F Stipoljev, H Tittelbach, X Fan, F Vasheghani, SS Hussein, M Volleth, T Liehr.
Mitotic stability of small supernumerary marker chromosomes – a study based on 93 immortalized cell lines.
Cytogenet Genome Res 2014, 142:151-160. 		1.561 sSMC
480
 		W Supiwong, T Liehr, MB Cioffi, A Chaveerach, N Kosyakova, K Pinthong, T Tanee, A Tanomtong.
Chromosomal evolution in naked catfishes (Bagridae, Siluriformes): A comparative chromosome mapping study.
Zool Anzeiger 2014, 253:316-320.		 1.483 EVO
479
 		X Fan, W Sangpakdee, A Tanomtong, A Chaveerach, K Pinthong, S Pornnarong, W Supiwong, V Trifonov, G Hovhannisyan, K Loth, C Hensel, T Liehr, A Weise.
Comprehensive molecular cytogenetic analysis of Barbary macaque (Macaca sylvanus).
Biol J Arm 2014, 66:98-102. 		n.a. EVO
478
 		X Fan, W Sangpakdee, A Tanomtong, A Chaveerach, K Pinthong, S Pornnarong, W Supiwong, VA Trifonov, GG Hovhannisyan, RM Aroutouinian, T Liehr, A Weise.
Molecular cytogenetic analysis of Thai southern pig-tailed macaque (Macaca nemestrina) by multicolor banding.
Proceedings of Yerevan State University 2014, 2014:46-50. 		n.a. EVO
477
 		CF Yano, J Poltronieri, LAC Bertollo, R Ferreira Artoni, T Liehr, M de Bello Cioffi.
Chromosomal mapping of repetitive DNAs in Triportheus trifurcatus (Characidae, Characiformes): Insights into the differentiation of the Z and W chromosomes.
PLOS One 2014, 9:e90946. 		3.234 EVO
476
 		YB Yurov, SG Vorsanova, T Liehr, AD Kolotii, IY Iourov.
X chromosome aneuploidy in the Alzheimer's disease brain.
Mol Cytogenet 2014, 7:20.
 		2.140 INT
475
 		F Santiago, G Alves, UB Otero, MM Tabalipa, LR Scherrer, N Kosyakova, MH Ornellas, T Liehr.
Monitoring of gas station attendants exposure to benzene, toluene, xylene (BTX) using three-color chromosome painting.
Mol Cytogenet 2014, 7:15. 		2.140 TCG
474
 		E Manolakos, A Vetro, A Garas, L Thomaidis, K Kefalas, G Kitsos, M Ziegler, T Liehr, O Zuffardi, I Papoulidis.
A new case of proximal 10q duplication in a child with severe central hypotonia characterized by array CGH and review.
Exp Therap Med 2014, 7:953-957. 		1.269 CG
473
 		T Liehr, H Heng, Y Yurov.
Reviewer acknowledgement 2014.
Mol Cytogenet 7:11.  		2.140 other
472
 		SS Bhatt, M Manvelyan, K Moradkhani, F Hunstig, K Mrasek, J Puechberty, G Lefort, P Sarda, A Weise, T Liehr, F Pellestor.
Inverted segment size and the presence of recombination hot spot clusters matter in sperm segregation analysis.
Cytogenet Genome Res 2014, 142:145-149. 		1.561 CG
INT
471
 		I Pappoulidis, E Papageorgiou, E Siomou, E Oikonomidou, L Thomaidou, A Vetro, O Zuffardi, T Liehr, E Manolakos.
A patient with partial trisomy 21 and 7p deletion expresses mild Down syndrome phenotype.
Gene 2014, 536:441-443.  		2.138 CG
470
 		W Al Achkar A Aljapawe, T Liehr, A Wafa.
De novo acute myeloid leukemia subtype-M4 with initial trisomy 8 and later acquired t(3;12)(q26;p12) leading to ETV6/MDS1/EVI1 fusion transcript expression: A case report.
Onc Lett 2014, 7:787-790.		 0.987 TCG
469
 		I Iourov, Y Yurov, H Heng, T Liehr.
In memoriam of Anna D Polityko (17.12.1959 -  20.04.2013).
Mol Cytogenet 2014, 7:2. 		2.140 other
468
 		L Rodríguez, SS Bhatt, M García-Castro, A Plasencia, J Fernández-Toral, E Abarca, M de Bello Cioffi, T Liehr.
 A unique case of a discontinuous duplication 3q26.1-3q28 resulting from a segregation error of a maternal complex chromosomal rearrangement involving an insertion and an inversion.
Gene 2014, 535:165-169. 		2.138 CG
467
 		J Poltronieri, V Marquioni, LAC Bertollo, E Kejnovsky, WF Molina, T Liehr, MB Cioffi.
Comparative chromosomal mapping of microsatellites in Leporinus species (Characiformes, Anostomidae): Unequal accumulation on the W chromosomes.
Cytogenet Genome Res 2014, 142:40-45. 		1.561 EVO
466
 		T Schmidt, T Bierhals, F Kortüm, I Bartels, T Liehr, P Burfeind, M Shoukier, V Frank, C Bergmann, K Kutsche.
 Branchio-Otic syndrome caused by a genomic rearrangement: clinical findings and molecular cytogenetic studies in a patient with a pericentric inversion of chromosome 8.
Cytogenet Genome Res 2014, 142:1-6.		 1.561 CG
68% of publications of Institute of Human Genetics Jena in the actual year


2013
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
465
 		T Liehr.
Anna D. Polityko (1959-2013).
ECA newsletter 2013, 32:37.
 		n.a.
 		other
464
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2013, 32:6-7. 		n.a. sSMC
463
 		T Jančušková, R Plachý, J Štika, L Krutílková, DW Hardekopf, T Liehr, N Kosyakova, R Čmejla, L Žejšková, T Kozák, P Žák, M Karas, S Peková.
Identifikace novych molekularnich “marker pro sledovani minimalni rezidualni nemoci u akutnich leumkemii.
Transfuze a Hematologie Dnes 2013, 19:8-21. 		n.a. TCG
M
462
 		T Liehr.
Copy number variations - is there a biological difference between submicroscopic and microscopically visible ones?
OA Genetics 2013, 1:2. 		n.a. HET
461
 		W Al-Achkar, Wafa A, Al-Ablog A, Moassas F, T Liehr.
Molecular cytogenetic characterization on an inv(Y)(p11.2q11.221q11.222) in a Syrian family.
Balk J Med Genet 2013, 16:73-76.  		0.167 CG
460
 		FY AbdElmontalab, IE Fadl, HM Abushama, K Kreskowski, T Liehr.
Molecular cytogenetic study of the NF2 gene deletion in meningioma in Sudanese patients.
Balk J Med Genet 2013, 16:29-32.  		0.167 TCG
459
 		FJ Sheth, T Liehr, P Kumari, R Akinde, HJ Sheth, JJ Sheth.
Chromosomal abnormalities in couples with repeated fetal loss: an Indian retrospective study.
Indian J Hum Genet 2013, 19:415-422.  		n.a. CG
458
 		RS Guilherme, MC Cernach, TE Sfakianakis, SS Takeno, LM Nardozza, C Rossi, SS Bhatt, T Liehr, MI Melaragno.
A complex chromosome rearrangement involving four chromosomes, nine breakpoints and a cryptic 0.6-Mb deletion in a boy with cerebellar hypoplasia and defects in skull ossification.
Cytogenet Genome Res 2013, 141:317-323. 		1.905 CG
457
 		N Karadeniz, T Liehr, K Mrasek, I Aşık, Z Aşık, N Kosyakova, H Mkrtchyan.
C-type lectins and human epithelial membrane protein1: Are they new proteins in keratin disorders?
Open J Genet 2013, 3:262-269. 		n.a. CG
456
 		X Fan, K Pinthong, H Mkrtchyan, P Siripiyasing, N Kosyakova, W Supiwong, A Tanomtong, A Chaveerach, T Liehr, M de Bello Cioffi, A Weise.
First detailed reconstruction of the karyotype of Trachypithecus cristatus (Mammalia: Cercopithecidae).
Mol Cytogenet 2013, 6:58. 		2.660 EVO
455
 		W Al Achkar, A Wafa, A Aljapawe, MAK Othman, T Liehr.
A novel cytogenetic abnormality r(7)(::p11.2->q36.3::) in a Philadelphia-positive chronic myeloid leukemia case.
Case Rep Clin Med 2013, 2:517-520.   		n.a. TCG
454
 		W Supiwong, T Liehr, MB Cioffi, A Chaveerach, N Kosyakova, K Pinthong, T Tanee, A Tanomtong.
Karyotype and cytogenetic mapping of 9 classes of repetitive DNAs in the genome of the naked catfish Mystus bocourti (Siluriformes, Bagridae).
Mol Cytogenet 2013, 6:51.  		2.660 EVO
453
 		MB Cioffi, T Liehr, V Trifonov, WF Molina, LAC Bertollo.
Independent sex chromosome evolution in lower vertebrates: A molecular cytogenetic overview in the Erythrinidae fish family.
Cytogenet Genome Res 2013, 141:186-194. 		1.905 EVO
452
 		T Liehr, S Cirkovic, T Lalic, M Guc-Scekic, C de Almeida, J Weimer, I Iourov, MI Melaragno, RS Guilherme, E-GG Stefanou, D Aktas, K Kreskowski, E Klein, M Ziegler, N Kosyakova, M Volleth, AB Hamid.
Complex small supernumerary marker chromosomes – an update.
Mol Cytogenet 2013, 6:4. 		2.660 sSMC
451
 		AD Bhatt, T Liehr, SR Bakshi.
Phenotypic spectrum in uniparental disomy: low incidence or lack of study?
Indian J Hum Genet 2013, 19:311-314. 		n.a. UPD
450
 		N Aust, S Schüle, AK Altendorf-Hofmann, Y Chen, T Knösel, O Dirsch, U Settmacher, A Weise, K Mrasek, T Liehr.
Loss of chromosome 4 correlates with better long-term survival and lower relapse rate after R0-resection of colorectal liver metastases.
J Cancer Res Clin Oncol 2013, 139:1861-1867. 		3.009 TCG
449
 		A Vičić, D Zudenigo, P Korać, T Liehr, F Stipoljev.
Prenatally detected interstitial deletion 13q12.3-q22 in a fetus with a cystic hygroma.
Gene 2013, 531:90-91. 		2.082 CG
448
 		DS Vasconcelos, FPE da Silva, LG Quintana, NP Anselmo, MAK Othman, T Liehr, EHC de Oliveira.
Numerical aberrations of chromosome 17 and TP53 in brain metastases derived from breast cancer.
Genet Mol Res 2013, 12:2594-2600. 		0.850 TCG
447
 		W Al Achkar, F Moassass, A Ikhtiar, MAK Othman, T Liehr, A Wafa.
Cytogenetic evolution in a patient with chronic developing a secondary acute myelogenous leukemia subtype M5 resistant to Imatinib mesylate therapy.
J Leuk 2013, 1:118. 		n.a. TCG
446
 		T Jancuskova, R Plachy, J Stika, L Zemankova, DW Hardekopf, T Liehr, N Kosyakova, R Cmejla, L Zejskova, T Kozak, P Zak, A Zavrelova, P Havlikova, M Karas, A Junge, C Ramel, S Pekova.
A method to identify new molecular markers for assessing minimal residual disease in acute leukemia patients.
Leuk Res 2013, 37:1363-1373. 		2.692 TCG
M
445
 		RS Guilherme, E Klein, AB Hamid, S Bhatt, M Volleth, A Polityko, A Kulpanovich, A Dufke, B Albrecht, S Morlot, L Brecevic, MB Petersen, E Manolakos, N Kosyakova, T Liehr.
Human ring chromosomes – new insights for their clinical significance.
Balk J Med Genet 2013, 16:13-19. 		0.167 CG
444
 		W Al Achkar, A Wafa, A Aljapawe, T Liehr.
A de novo del(9)(p22.3) in a primary plasma cell leukemia case.
Mol Cytogenet 2013, 6:33. 		2.660 TCG
443
 		T Liehr, H Heng, Y Yurov, A Meloni-Ehrig, I Iourov.
Molecular Cytogenetics: the first impact factor (2.36).
Mol Cytogenet 2013, 6:28. 		2.660 other
442
 		MAM Abo-Zeid, T Liehr , SM El-Daly, AM Gamal-Eldeen, M Glei, A Shabaka, S Bhatt, A Hamid.
Molecular cytogenetic evaluation of the efficacy of photodynamic therapy by Indocyanine Green in breast adenocarcinoma MCF-7 cells.
Photodiagn Photodynam Therapy 2013, 10:194-202. 		2.524 TCG
441
 		RS Guilherme, ARN Dutra, ABA Perez, SS Takeno, MM Oliveira, LD Kulikowski, E Klein, AB Hamid, T Liehr, MI Melaragno.
First report of a small supernumerary der(8;14) marker chromosome.
Cytogenet Genome Res 2013, 139:284-288.		 1.905 sSMC
440
 		E Manolakos, A Vetro, E Papadopoulou, K Kefalas, M Lagou, L Thomaidis, P Peitsidis, S Sifakis, A Divane, M Ziegler, T Liehr, O Zuffardi, I Papoulidis.
Partial trisomy 2p and partial monosomy 2q arising from a paternal intrachromosomal 2q-into-2p between-arm insertion and paracentric inversion: molecular cytogenetic characterization of a four break rearrangement.
Cytogenet Genome Res 2013, 140:12-20. 		1.905 CG
439
 		T Liehr, E Klein, K Mrasek, N Kosyakova, RS Guilherme, N Aust, C Venner, A Weise, AB Hamid.
Clinical impact of somatic mosaicism in cases with small supernumerary marker chromosomes.
Cytogenet Genome Res 2013, 139:158-163.		 1.905 sSMC
438
 		T Liehr, H Heng, Y Yurov.
Reviewer acknowledgement 2013.
Mol Cytogenet 2013, 6:9.
 2.660 other
437
 		T Liehr, A Weise, AB Hamid, X Fan, E Klein, N Aust, MAK Othman, K Mrasek, N Kosyakova.
Multicolor FISH methods in current clinical diagnostics.
Exp Rev Mol Diag 2013, 13:251-255. 		4.270 M
436
 		W Al-Achkar, A Wafa, M Assaad, C Ehlers, T Liehr.
A unique case of female pseudohermaphroditism with 21-hydroxylase deficiency and small supernumerary marker chromosome 7.
Mol Med Rep 2013, 7:1545-1548. 		1.484 sSMC
435
 		W Al-Achkar, A Wafa, A Ikhtiar, T Liehr. T
Three-way Philadelphia translocation t(9;10;22)(q34;p11.2;q11.2) as a secondary abnormality in an imatinib mesylate-resistant chronic myeloid leukemia patient.
Oncol Lett 2013, 5:1656-1658. 		0.987 TCG
434
 		W Al-Achkar, A Wafa, F Moassass, E Klein, T Liehr.
Multiple copies of BCR-ABL fusion gene on two isodicentric Philadelphia chromosomes in an imatinib mesylate-resistant chronic myeloid leukemia patient.
Oncol Lett 2013, 5:1579-1582. 		0.987 TCG
433
 		N Kosyakova, A Grigorian, T Liehr, M Manvelyan, I Simonyan, H Mkrtchyan, R Aroutiounian, AD Polityko, AI Kulpanovich, T Egorova, E Jaroshevich, A Frolova, N Shorokh, IV Naumchik, M Volleth, I Schreyer, H Nelle, M Stumm, R-D Wegner, G Reising-Ackermann, M Merkas, L Brecevic, T Martin, L Rodríguez, S Bhatt, M Ziegler, K Kreskowski, A Weise, A Sazci, S Vorsanova, M de Bello Cioffi, E Ergul.
Heteromorphic variants of chromosome 9.
Mol Cytogenet 2013, 6:14.  		2.660 HET
432
 		T Liehr, N Kosyakova.
Small supernumerary marker chromosomes (sSMC) – what about the genotype-phenotype correlation?
Tsitologiya 2013, 55:165-166. 		n.a. sSMC
431
 		N Kosyakova, V Trifonov, S Romanenko, H Mkrtchyan, A Graphodatsky, T Liehr.
Murine multicolor banding.
Tsitologiya 2013, 55:259-260. 		n.a. M
430
 		C Leibiger, N Kosyakova, H Mkrtchyan, M Glei, V Trifonov, T Liehr.
First molecular cytogenetic high resolution characterization of the NIH 3T3 cell line by murine multicolor banding.
J Histochem Cytochem 2013, 61:306-312. 		2.403 TCG
429
 		RRC Matos, H Mkrchyan, BA Amaral, T Liehr, MT de Souza, DR Ney-Garcia, N Santos, TJ Marques-Salles, RC Ribeiro, AF Figueiredo, MLM Silva.
An unusual cytogenetic rearrangement originating from two different abnormalities in chromosome 6 in a child with acute promyelocytic leukemia.
Acta Hematologica 2013, 130:23-26. 		0.850 TCG
428
 		TV Karamysheva, МА Prokhorovich, MA Lagarkova, SL Kiselev, T Liehr, NB Rubtsov.
Chromosome rearrangements in sublines of human embryonic stem cell lines hESM01 and hESM03.
BioDiscovery 2013, 7:1.  		n.a. CG
427
 		B Cavdarli, G Ozgen, AO Kaymak, B Göker, T Liehr, MA Ergun, EF Percin.
A case with double translocation and Sjögren syndrome.
Turkiye J Med Sci 2013, 33:233-236.  		0.841 CG
426
 		JC Barber, V Hall, VK Maloney, S Huang, AM Roberts, AF Brady, N Foulds, B Bewes, M Volleth, T Liehr, K Mehnert, M Bateman, H White.
16p11.2-p12.2 duplication syndrome; a genomic condition differentiated from euchromatic variation of 16p11.2.
Eur J Hum Genet 2013, 21:182-189.  		4.225 CG
425
 		DR Ney-Garcia, TP Vieira, T Liehr, S Bhatt, MT de Souza, AF de Figueiredo, RC Ribeiro, MLM Silva.
A case of childhood T cell acute lymphoblastic leukemia with a complex t(9;9) and homozygous deletion of CDKN2A gene associated with a Philadelphia-positive minor subclone.
Blood Cells Mol Dis 2013, 50:131-133. 		2.331 TCG
424
 		T Schmidt, I Bartels, T Liehr, P Burfeind, B Zoll, M Shoukiera.
A family with an inverted tandem duplication 5q22.1q23.2.
Cytogenet Genome Res 2013,139:65-70. 		1.905 CG
423
 		J Ou, W Wang, T Liehr, E Klein, AB Hamid, F Wang, C Duan, H Li.
Characterization of three small supernumerary marker chromosomes (sSMC) in humans.
J Matern Fetal Neonatal Med 2013, 26:106-108. 		1.208 sSMC
422
 		W Al-Achkar, A Wafa, T Liehr.
A new t(9;11;20;22)(q34;p11.2;q11.21;q11) in a Philadelphia-positive chronic myeloid leukemia case.
Oncol Lett 2013, 5:605-608. 		0.987 TCG
421
 		W Al-Achkar, A Aljapawe, S Almedani, T Liehr, A Wafa.
A novel cytogenetic abnormality t(7;8)(p11.2;q11.2) and a four-way Philadelphia translocation in an imatinib mesylate-resistant chronic myeloid leukemia patient.
Oncol Lett 2013, 5:617-620. 		0.237 TCG
52% of publications of Institute of Human Genetics Jena in the actual year


2012
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
420
 		T Liehr.
PWG: Marker chromosomes
ECA newsletter 2012, 31:26. 		n.a.
 		sSMC
419
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2012, 30:23-24. 		n.a. sSMC
418
 		AB Hamid, A Weise, M Voigt, M Bucksch, N Kosyakova, T Liehr, E Klein.
Clinical impact of proximal autosomal imbalances.
Balk J Med Genet 2012, 15:15-21. 		0.077 sSMC
417
 		F Sheth, N Gohel, T Liehr, O Akinde, M Desai, O Adeteye, J Sheth.
Gain of chromosome 4qter and loss of 5pter – an unusual case with features of Cri du chat syndrome (CdCS).
Case Reports Genet 2012, 2012:153405.
 		n.a. CG
416
 		RS Guilherme, E Klein, C Venner, AB Hamid, S Bhatt, MI Melaragno, M Volleth, A Polityko, A Kulpanovich, N Kosyakova, T Liehr.
Human ring chromosomes and small supernumerary marker chromosomes – do they have telomeres?
Chromosome Res 2012; 20:825-835. 		2.847 sSMC
415
 		NLL Corrales, K Mrasek, M Voigt, T Liehr, N Kosyakova.
Comprehensive characterization of genomic instability in pluripotent stem cells and their derived neuroprogenitor cell lines.
Applied & Translational Genomics 2012, 1:21-24. 		n.a. CG
414
 		MAK Othman, A Lier, S Junker, P Kempf, F Dorka, E Gebhart, FJ Sheth, B Grygalewicz, S Bhatt, A Weise, K Mrasek, T Liehr, M Manvelyan.
Does positioning of chromosomes 8 and 21 in interphase drive t(8;21) in acute myelogenous leukemia?
BioDiscovery 2012, 4:4. 		n.a. INT
TCG
413
 		K Ma, L Qiu, K Mrasek, J Zhang, T Liehr, LG Quintana, Z Li.
Common fragile sites: genomic hotspots of DNA damage and carcinogenesis.
Int J Mol Sci 2012, 13:11974-11999. 		2.464 TCG
INT
412
 		A Serra, K Eirich, AK Winkler, K Mrasek, G Göhring, G Barbi, H Cario, B Schlegelberger, B Royer-Pokora, T Liehr, C Leriche, D Henne-Bruns, TF Barth, D Schindler.
Shared copy number variation in simultaneous nephroblastoma and neuroblastoma due to Fanconi anemia.
Mol Syndromol 2012, 3:120-130.		 n.a. TCG
411
 		NLL Corrales, K Mrasek, M Voigt, T Liehr, N Kosyakova.
Copy number variations (CNVs) in human pluripotent cell-derived neuroprogenitors.
Gene 2012, 506:377-379.		 2.196 CG
410
 		AB Hamid, K Kreskowski, A Weise, N Kosayakova, K Mrasek, M Voigt, RS Guilherme, R Wagner, D Hardekopf, S Pekova, T Karamysheva, T Liehr, E Klein.
How to narrow down chromosomal breakpoints in small and large derivative chromosomes – a new probe set.
J Appl Genet 2012, 53:259-269.		 1.847 M
sSMC
409
 		M Bucksch, M Ziegler, N Kosayakova, MV Mulhatino, JC Llerena Jr., S Morlot, W Fischer, AD Polityko, AI Kulpanovich, MB Petersen, B Belitz, V Trifonov, A Weise, T Liehr, AB Hamid.
A new multicolor-fluorescence in situ hybridization probe set directed against human heterochromatin: HCM-FISH.
J Histochem Cytochem 2012, 60:530-536.		 2.255 M
HET
408
 		MV Mulatinho, C Luiz de Carvalho Serao, F Scalco, D Hardekopf, S Pekova, K Mrasek, T Liehr, A Weise, N Rao, JC Llerena Jr.
Severe intellectual disability, omphalocele, hypospadia and high blood pressure associated to a deletion at 2q22.1q22.3: Case report.
Mol Cytogenet 2012, 5:30.		 2.360 CG
407
 		W Al-Achkar, A Wafa, T Liehr, E Klein, F Moassass.
Detailed analysis of an idic(Y)(q11.21) in a mosaic karyotype.
Mol Med Report 2012, 6:293-296.		 1.170 CG
406
 		W Al-Achkar, A Wafa, F Moassass, T Liehr.
A unique cytogenetic abnormality, t(2;7)(p13.1;p21.3), in a Philadelphia-positive chronic myeloid leukemia.
Onc Letters 2012, 4:209-212.		 0.237 TCG
405
 		I Papoulidis, E Manolakos, AB Hamid, E Klein, N Kosyakova, U Kordaß, J Kunz, E Siomou, M Kontodiou, M Tzimina, P Nicolaides, T Liehr, MB Petersen.
Tetrasomy 9p mosaicism associated with a normal phenotype in two cases.
Cytogenet Genome Res 2012, 136:237-241.		 1.839 sSMC
404
 		A Faria de Figueiredo, TP Vieira, T Liehr, S Bhatt, R Binato, T de Jesus Marques Salles, E Carboni, RC Ribeiro, ML Macedo Silva, E Abdelhay.
A rare cryptic and complex rearrangement leading to MLL-MLLT10 gene fusion masked by del(10)(p12) in a child with acute monoblastic leukemia (AML-M5).
Leuk Res 2012, 36:e74-e77.
 2.764 TCG
403
 		A Weise, K Mrasek, E Klein, M Mulatinho, JC Llerena Jr., D Hardekopf, S Pekova, S Bhatt, N Kosyakova, T Liehr.
Microdeletion and microduplication syndromes.
J Histochem Cytochem 2012, 60:346-358.
2.255
 		CG
402
 		E Klein, M Rocchi, A Ovens-Raeder, N Kosyakova, A Weise, M Ziegler, M Meins, S Morlot, W Fischer, M Volleth, A Polityko, C Mackie Ogilvie, C Kraus, T Liehr.
Five novel locations of neocentromeres in human: 18q22.1, Xq27.1~27.2, acro p13, acro p12, and heterochromatin of unknown origin.
Cytogenet Genome Res 2012, 136:163-166. 		1.839 CG
sSMC
401
 		MA Fonzar Hernandes, T de Jesus Marques-Salles, H Mkrtchyan, EM Soares-Ventura, E Pereira Leite, MT Cartaxo Muniz, MT Marquim Nogueira Cornélio, T Liehr, N Santos, ML Macedo Silva.
Extra copies of der(21)t(12;21) plus deletion of ETV6 gene due to dic(12;18) in B-cell precursor ALL with poor outcome.
Case Reports Genet 2012, 2012:186532. 		n.a. TCG
400
 		A Vetro, E Manolakos, MB Petersen, L Thomaidis, T Liehr G Croci, F Franchi, M Marinelli, E Meneghelli, B Dal Bello, S Cesari, A Iasci, G Arrigo, O Zuffardi.
Unexpected results in the constitution of small supernumerary marker chromosomes.
Europ J Med Genet 2012, 55:185–190. 		1.685 sSMC
399
 		G Hovhannisyan, R Aroutiounian, T Liehr.
Chromosomal composition of micronuclei in human leukocytes exposed to mitomycin C.
J Histochem Cytochem 2012, 60:316-322.		 2.255 TCG
398
 		E Klein, M Manvelyan, I Simonyan, AB Hamid, R Santos Guilherme, T Liehr, T Karamysheva.
Centromeric association of small supernumerary marker chromosomes with their sister-chromosomes detected by three dimensional molecular cytogenetics.
Mol Cytogenet 2012, 5:15.		 2.410 sSMC
INT
397
 		W Al-Achkar, A Wafa, F Moassass, T Liehr.
A chronic myeloid leukemia case with a unique variant Philadelphia translocation: t(9;22;21)(q34;q11;p12).
Oncol Lett 2012, 3:1027-1029.		 0.237 TCG
396
 		E Manolakos, S Sifakis, S Sotiriou, P Peitsidis, M Eleftheriades, V Mersinias, T Liehr, L Thomaidis, G Kitsos, I Papoulidis, MB Petersen, S Orru S.
Prenatal detection of an inverted duplication deletion in the long arm of chromosome 1 in a fetus with increased nuchal translucency. Molecular cytogenetic analysis and review of the literature.
Clin Dysmorphol 2012, 21:101-105.		 0.608 CG
395
 		DR Ney-Garcia, T Liehr, S Bhatt, MT de Souza, RR de Matos, G Pimenta, W Pulcheri, RC Ribeiro, E Abdelhay, MLM Silva.
Childhood B-cell progenitor acute lymphoblastic leukemia presenting a three-way t(11;12;21)(q14;p13;q22) with a RUNX1 gene signal on chromosome 11.
Int J Hematol 2012, 95:112-114.		 1.681 TCG
394
 		DR Ney-Garcia, T Liehr, S Bhatt, MT de Souza, RR Capela de Matos, R Binato, FC Jordy, E Abdelhay, RC Ribeiro, MLM Silva.
Molecular cytogenetic studies reveal an unexpected chromosomal inversion as a variant of t(12;21)(p13;q22) in a child with B-cell precursor acute lymphoblastic leukemia.
Leuk Lymphoma 2012, 53:342-344.		 2.301 TCG
393
 		C Eckmann-Scholz, H Tönnies, T Liehr, S Gesk, W Jonat, A Caliebe.
Normal prenatal ultrasound findings in a case with de novo mosaic small supernumerary marker chromosome 18 – how to counsel?
J Mat-Fet Neonat Med 2012, 25:200-202.  		1.518 sSMC
48% of publications of Institute of Human Genetics Jena in the actual year


2011
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
392
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2011, 27:6.		 n.a.
 		sSMC
391
 		C Backsch, B Pauly, M Liesenfeld, C Scheungraber, M Gajda, K Mrasek, T Liehr, A Clad, E Schröck, IB Runnebaum, M Dürst.
Two novel unbalanced whole arm translocations are frequently detected in cervical squamous cell carcinoma.
Cancer Genetics 2011, 204:646-653.		 n.a. TCG
390
 		C Woelfel, T Liehr, A Weise, J Langrehr, W Amin Kotb, M Pacyna-Gengelbach, D Katenkamp, I Petersen.
Molecular cytogenetic characterization of epithelioid hemangioendothelioma.
Cancer Genetics 2011, 204:671-676.		 n.a. TCG
389
 		T Milenkovic, M Guc-Scekic, D Zdravkovic, V Topic, T Liehr, G Joksic, D Radivojevic, N Lakic.
Molecular analysis of ring Y chromosome in a 10-year-old boy with mixed gonadal dysgenesis and growth hormone deficiency.
Balk J Med Genet 2011, 14:71-75.		 0.225 CG
388
 		T Liehr, N Kosayakova, J Schröder, M Ziegler, K Kreskowski, B Pohle, S Bhatt, L Theuss, K Wilhelm, A Weise, K Mrasek.
Evidence for correlation of fragile sites and chromosomal breakpoints in carriers of constitutional balanced chromosomal rearrangements.
Balk J Med Genet 2011, 14:13-16.		 0.225 CG
INT
387
 		V Westrich, T Liehr.
Molecular cytogenetic approaches and array-diagnostics in prenatal medicine.
Med Genetik 2011, 22:463-468.		 0.059 PRE
M
386
 		G Dobbernack, W Meinl, N Schade, S Florian, K Wend, I Voigt, H Himmelbauer, M Gross, T Liehr, H Glatt.
Altered tissue distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adducts in mice transgenic for human sulfotransferases 1A1 and 1A2.
Carcinogenesis 2011, 32:1734-1740.		 5.702 TCG
385
 		M de Bello Cioffi, A Sánchez, JA Marchal, N Kosyakova, T Liehr, V Trifonov, LA Bertollo.
Whole chromosome painting reveals independent origin of sex chromosomes in closely related forms of a fish species.
Genetica 2011, 139:1065-1072.		 2.148 EVO
384
 		F Braulke, J Schanz, R Steffens, T Liehr, M Manvelyan, I Chudoba, D Haase.
Two different del(5q) clones in a patient with myelodysplastic syndrome.
Leuk Lymph 2011, 52:1811-1844.		 2.580 TCG
383
 		O Villa, M Mallo, N Kosyakova, M Salido, T Liehr, L Martínez-Avilés, C Pedro, M García-Aragonés, B Espinet, L Florensa, L Arenillas, I Cuscó, LA Pérez Jurado, F Solé.
Deletion of TET2 gene in an acute myeloid leukemia case with a t(4;15)(q24;q26) characterized by glass needle based chromosome microdissection and oligonucleotide array.
Leuk Res 2011, 35: e161– e163.		 2.923 TCG
382
 		T Liehr, E Ewers, AB Hamid, N Kosyakova, M Voigt, A Weise, M Manvelyan.
Small supernumerary marker chromosomes and uniparental disomy have a story to tell.
J Histochem Cytochem 2011, 59:842-848.		 2.725 sSMC
UPD
381
 		L Kraoua, M Chaabouni, E Ewers, I Chelly, I Ouertani, LB Jemaa, F Maazoul, T Liehr, H Chaabouni.
Hexasomy of the Prader-Willi/Angelman critical region, including the OCA2 gene in a patient with pigmentary dysplasia: case report.
Europ J Med Genet 2011, 54:e446-450.		 2.178 CG
380
 		A Faria de Figueiredo, T Liehr, S Bhatt, R Binato, M Tavares de Souza, R Rodrigues Capela de Matos, T de Jesus Marques Salles, FC Jordy, RC Ribeiro, E Abdelhay, ML Macedo Silva.
A complex karyotype masked a cryptic variant t(8;21)(q22;q22) in a child with acute myeloid leukemia.
Leuk Lymph 2011, 52:1593-1596.  		2.580 TCG
379
 		MB Cioffi, A Sánchez, JA Marchal, N Kosyakova, T Liehr, V Trifonov, LAC Bertollo.
Cross-species chromosome painting tracks the independent origin of multiple sex chromosomes in two cofamiliar Erythrinidae fishes.
BMC Evolutionary Biology 2011, 11:186. 		3.521 EVO
378
 		M Stuhrmann-Spangenberg, H Engels, B Fritz, H Gabriel, D Gläser, W Henn, T Liehr, K Miller, H Rieder.
S2-Leitlinie Humangenetische Diagnostik.
Med Genetik 2011, 23:281-323. 		0.059 other
377
 		F Pellestor, T Anahory, G Lefort, J Puechberty, T Liehr, B Hédon, P Sarda.
Complex chromosomal rearrangements: origin and meiotic behavior.
Hum Reprod Update 2011, 17:476-494.  		9.234 CG
376
 		F Pellestor, J Puechberty, A Weise, G Lefort, T Anahory, T Liehr, P Sarda.
Meiotic segregation of complex reciprocal translocations: direct analysis of the spermatozoa of a t(5;13;14) carrier.
Fertil Steril 2011, 95:2433.e17-2433.e22. 		3.564 CG
375
 		E Manolakos, A Vetro, K Kefalas, L Thomaidis, G Aperis, S Sotiriou, G Kitsos, M Merkas, S Sifakis, I Papoulidis, T Liehr, O Zuffardi, MB Petersen.
Deletion 2q31.2-q31.3 in a 4-year-old girl with microcephaly and severe mental retardation.
Am J Med Genet A 2011, 155:1476-1482. 		2.391 CG
374
 		JB Melo, L Backx, JR Vermeesch, HG Santos, AC Duarte, N Kosyakova, A Weise, F von Eggeling, T Liehr, IM Carreira.
Chromosome 5 derived small supernumerary marker: towards a genotype/phenotype correlation of proximal chromosome 5 imbalances.
J Appl Genet 2011, 52:193-200. 		1.664 sSMC
373
 		FJ Sheth, J Andrieux, E Ewers, N Kosyakova, A Weise, H Sheth, S-P Romana, M LeLorc’h, B Deloben, O Theisen, T Liehr, S Numpoothiri, J Sheth.
Characterization of sSMC by FISH and molecular techniques.
Europ J Med Genet 2011, 54:247-255. 		2.178 sSMC
372
 		EM Soares-Ventura, H Mkrtchyan, T de Jesus Marques-Salles, M Silva, N Santos, B de Araujo Silva Amaral, T Liehr, E Abdelhay, ML Macedo Silva, MT Cartaxo Muniz.
Molecular cytogenetics reveals complex karyotype in apparent t(8;13) therapy-related acute myeloid leukemia M2 after fibrosarcoma.
Leuk Res 2011, 35:e27–e29. 		2.923 TCG
371
 		B Horsthemke, M Wawrzik, S Groß, C Lich, B Sauer, I Rost, E Krasemann, N Kosyakova, T Liehr, A Weise, JN Dybowski, D Hoffmann, D Wieczorek.
Parental origin and functional relevance of a de novo UBE3A variant.
Europ J Med Genet 2011, 54:19-24. 		2.178 UPD
CG
370
 		M Tavares de Souza, H Mkrtchyan, R Hassan, D Ribeiro Ney Garcia, AM Boulhosa de Azevedo, E Sobral da Costa, A Faria de Figueiredo, T Liehr, E Abdelhay, ML Macedo Silva.
Secondary abnormalities involving 1q or 13q and poor outcome in high stage Burkitt leukemia/lymphoma cases with 8q24 rearrangement at diagnosis.
Int J Hematol 2011, 93:232-236. 		1.268 TCG
369
 		W Al-Achkar, A Wafa, T Liehr.
Complex translocation involving four chromosomes in a novel Philadelphia-positive chronic myeloid leukemia case.
Onc Lett 2011, 2:273-276. 		0.108 TCG
368
 		T Liehr.
What is uniparental disomy (UPD)? [online] Oxford Gene Technology.
originally available at: http://www.ogt.co.uk/cytosure_whatisUPD.html   		n.a. UPD
367
 		M Manvelyan, FW Cremer, J Lancé, R Kläs, C Kelbova, C Ramel, H Reichenbach, C Schmidt, E Ewers, K Kreskowski, M Ziegler, N Kosyakova, T Liehr.
New cytogenetically visible copy number variant in region 8q21.2.
Mol Cytogenet 2011, 4:1.  		2.410 HET
366
 		T Liehr, I Bartels, B Zoll, E Ewers, K Mrasek, N Kosyakova, M Merkas, AB Hamid, F von Eggeling, N Posorski, A Weise.
Is there a yet unreported unbalanced chromosomal abnormalities without phenotypic consequences in proximal 4p?
Cytogenet Genome Res 2011, 132:121-123.  		1.533 HET
46% of publications of Institute of Human Genetics Jena in the actual year


2010
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
365
 		K Karaer, MA Ergun, A Weise, E Ewers, T Liehr, N Kosyakova, H Mkrtchyan.
The case of an infertile male with an uncommon reciprocal X-autosomal translocation: how does this affect male fertility?
Genet Couns 2010, 21:397-404. 		0.395 CG
364
 		O Egritas, B Cavdarli, B Dalgic, MA Ergun, F Percin, M Ziegler, B Pohle, T Liehr.
Duplication 4q associated with chronic cholestatic changes in liver biopsy.
Eur J Med Genet 2010, 53:411-414. 		2.335 CG
363
 		E Manolakos, A Vetro, K Kefalas, SM Rapti, E Louizou, A Garas, G Kitsos, L Vasileiadis, P Tsoplou, M Eleftheriades, P Peitsidis, S Orru, T Liehr, MB Petersen, L Thomaidis.
The use of array-CGH in a cohort of Greek children with developmental delay.
Mol Cytogenet 2010, 3:22. 		n.a. CG
362
 		W Al-Achkar, A Wafa, M Manvelyan, A Ikhtiar, T Liehr.
De novo translocation involving two chromosomes in adult prolymphocytic leukemia - A rare case.
Leuk Res 2010, 34:e345-347.  		2.555 TCG
361
 		W Al Achkar, A Wafa, F Moassass, T Liehr.
Partial trisomy 9p22 to 9p24.2 in combination with partial monosomy 9pter in a Syrian girl.
Mol Cytogenet 2010, 3:18.		 n.a. CG
360
 		K Gersak, K Writzl, A Veble, T Liehr.
Primary amenorrhoea in a patient with mosaicism for monosomy X and a derivative X-chromosome.
Genet Couns 2010, 21:335-342. 		0.395 CG
359
 		T Liehr, T Karamysheva, M Merkas, L Brecevic, AB Hamid, E Ewers, K Mrasek, N Kosyakova, A Weise.
Somatic mosaicism in cases with small supernumerary marker chromosomes.
Curr Genomics 2010, 11:432-439.  		2.487 sSMC
358
 		H Mkrtchyan, M Gross, S Hinreiner, A Polytiko, M Manvelyan, K Mrasek, N Kosyakova, E Ewers, H Nelle, T Liehr, S Bhatt, K Thoma, E Gebhart, S Wilhelm, R Fahsold, M Volleth, A Weise.
The human genome puzzle – the role of copy number variation in somatic mosaicism.
Curr Genomics 2010, 11:426-431. 		2.487 INT
HET
357
 		A Faria de Figueiredo, T Liehr, S Bhatt, R Binato, EM Soares Ventura, M Tavares de Souza, R Rodrigues Capela de Matos, R Correa Ribeiro, E Abdelhay, ML Macedo Silva.
A new cryptic ins(11;1)(q23;q21q31) detected in a t(1;8;11)(q21;p21;q23) in a baby with acute myeloid leukemia FAB AML-M5.
Blood Cells Mol Dis 2010, 45:197-198.  		2.716 TCG
356
 		E Manolakos, K Kefalas, R Neroutsou, M Lagou, N Kosyakova, E Ewers, M Ziegler, A Weise, P Tsoplou, S-M Rapti, I Papoulidis, E Anastasakis, A Garas, S Sotiriou, M Eleftheriades, P Peitsidis, D Μalathrakis, L Thomaidis, G Kitsos, S Orru, T Liehr, MB Petersen, S Kitsiou-Tzeli.
Characterization of 23 small supernumerary marker chromosomes detected at pre-natal diagnosis: The value of fluorescence in situ hybridization.
Mol Med Rep 2010, 3:1015-1022. 		0.307 sSMC
355
 		W Al-Achkar, T Liehr, A Wafa.
 Insertion of the 3' ABL region into the long arm of chromosome 1 in a Philadelphia chromosome-negativechronic myeloid leukemia case.
Oncol Lett 2010, 1:951-954.
 		n.a. TCG
354
 		M Santos, K Mrasek, I Madrigal, MR Martorell, A González-Meneses, G Rodríguez-Criado, M Milà, T Liehr, C Fuster.
Characterization of a complex cryptic mosaicism for an sSMC derived from the X chromosome present in a boy with congenital malformations.
Am J Med Genet 2010, 152A:2161-2163. 		2.505 sSMC
353
 		S Balci, B Yuksel Konuk, F Atik, AK Oguz, MA Ergun, V Baltaci, N Kosyakova, T Liehr.
Partial deletion of the long arm of chromosome 13 (q32q33.2) associated with mental retardation, choanal atresia and fish mouth.
Genet Couns 2010, 21:317-324. 		0.395 CG
352
 		J Fernández-Toral, L Rodríguez, A Plasencia, ML Martínez-Frías, E Ewers, AB Hamid, M Ziegler, T Liehr.
Four small supernumerary marker chromosomes derived from chromosomes 6, 8, 11 and 12 in a patient with minimal clinical abnormalities – a case report.
J Med Case Reports 2010, 4:239.  		n.a. sSMC
351
 		W Al Achkar, A Wafa, H Mkrtchyan, F Moassass, T Liehr.
A unique complex translocation involving six different chromosomes in a case of childhood acute lymphoblastic leukemia with the Philadelphia chromosome and adverse prognosis.
Oncol Lett 2010, 1:801-804. 		n.a. TCG
350
 		W Al Achkar, A Wafa, BY Ali, M Manvelyan, T Liehr.
A rare chronic myeloid leukemia case with Philadelphia chromosome, BCR-ABL e13a3 transcript and complex translocation involving four different chromosomes.
Oncol Lett 2010, 1:797-800.		 n.a. TCG
349
 		W Al Achkar, A Wafa, H Mkrtchyan, F Moassass, T Liehr.
A rare case of Philadelphia chromosome-positive chronic myelogenous leukemia with inversion in chromosome 9 and t(10;17).
Oncol Lett 2010, 1:793-795.  		n.a. TCG
348
 		T Liehr.
A new internet page on uniparental disomy.
ECA-newsletter 2010, 26:22-24.  		n.a. UPD
347
 		SI Ferreira, E Matoso, M Pinto, J Almeida, T Liehr, JB Melo, IM Carreira.
X-chromosome terminal deletion in a female with premature ovarian failure: Haploinsufficiency of X-linked genes as a possible explanation.
Mol Cytogenet 2010, 3:14. 		n.a. CG
346
 		E Ewers, K Yoda, AB Hamid, A Weise, M Manvelyan, T Liehr.
Centromere activity in dicentric small supernumerary marker chromosomes.
Chromosome Res 2010; 18:555-562. 		3.130 sSMC
345
 		SB Niksic, VI Deretic, GR Pilic, E Ewers, M Merkas, M Ziegler, T Liehr.
Trisomy 21 with a small supernumerary marker chromosome derived from chromosomes 13/21 and 18.
Balk J Med Genet 2010, 13:55-58.  		0.075 sSMC
344
 		T de Jesus Marques-Salles, H Mkrtchyan, E Pereira Leite, EM Soares-Ventura, MT Cartaxo-Muniz, E Ferreira, T Liehr, ML Macedo Silva, N Santos.
Complex karyotype defined by molecular cytogenetic FISH and M-FISH in an infant with acute megakaryoblastic leukemia and neurofibromatosis.
Cancer Genet Cytogenet 2010, 200:167-169.
 		1.551 TCG
343
 		T de Jesus Marques-Salles, JEX da Silva Barros, EM Soares-Ventura, MT Cartaxo-Muniz, N Santos, E Ferreira, ML Macedo Silva, T Liehr, H Mkrtchyan.
Unusual childhood biphenotypic acute leukemia with a yet unreported t(3;13)(p25.1;q13).
Leuk Res 2010, 34:e206-e207.		 2.555 TCG
342
 		H Nelle, I Schreyer, E Ewers, K Mrasek, N Kosyakova, M Merkas, AB Hamid, A Weise, T Liehr.
Presence of harmless small supernumerary marker chromosomes hampers molecular genetic diagnosis: a case report.
Mol Med Rep 2010, 3:571-574.
 		0.307 sSMC
341
 		D Aktas, EG Utine, K Mrasek, A Weise, F von Eggeling, K Yalaz, N Posorski, N Akarsu, M Alikasifoglu, T Liehr, E Tuncbilek.
Derivative chromosome 1 and GLUT1 deficiency syndrome in a sibling pair.
Mol Cytogenet 2010, 3:10. 		n.a. CG
340
 		I Papoulidis, E Manolakos, E Siomou, K Kefalas, L Thomaidis, T Liehr, A Vetro, A Athanasiadis, O Zuffardi, MB Petersen.
A fetus with ring chromosome 21 characterized by aCGH shows no clinical findings after birth.
Prenat Diag 2010, 30:586-588.
 		2.152 CG
339
 		B Auber, P Burfeind, C Thiels, EA Alsat, M Shoukier, T Liehr, H Nelle, I Bartels, G Salinas-Riester, F Laccone.
 An unbalanced translocation resulting in a duplication of Xq28 causes a Rett syndrome-like phenotype in a female patient.
Clin Genet 2010, 77:593-597. 		2.942 CG
338
 		E Ktistaki, A Garefalaki, A Williams, SR Andrews, DM Bell, KE Foster, CG Spilianakis, RA Flavell, N Kosyakova, V Trifonov, T Liehr, D Kioussis.
CD8 locus nuclear dynamics during thymocyte development.
J Immunol 2010, 184:5686-5695. 		5.745 CG
337
 		E Uz, Y Alanay, D Aktas, I Vargel, S Gucer, G Tuncbilek, F von Eggeling, E Yilmaz, O Deren, N Posorski, H Ozdag, T Liehr, S Balci, M Alikasifoglu, B Wollnik, NA Akarsu.
Disruption of ALX1 causes extreme microphthalmia and severe facial clefting: expanding the spectrum of autosomal-recessive ALX-related frontonasal dysplasia.
Am J Hum Genet 2010, 86:789-796. 		11.680 CG
336
 		T Liehr, R-D Wegner, M Stumm, T Martin, G Gillessen-Kaesbach, N Kosyakova, E Ewers, AB Hamid, F von Eggeling, J Hentschel, M Ziegler, A Weise.
Three new cases with small supernumerary marker chromosomes 1 and normal phenotype.
J Chin Med Assoc 2010, 73: 205-207. 		0.678 sSMC
335
 		Z Li, Q Zhang, J-H Mao, A Weise, K Mrasek, X Fan, X Zhang, T Liehr, KH Lu, A Balmain, W-W Cai.
A HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis.
Oncogene 2010, 29:2659-2671. 		7.414 TCG
334
 		T Liehr, N Kosyakova, A Weise, M Ziegler, G Raabe-Meyer.
First case of a neocentromere formation in an otherwise normal chromosome 7.
Cytogenet Genome Res 2010, 218:189-191. 		1.783 CG
333
 		P Burégio-Frota, L Valença, GF Leal, AR Duarte, AV Bispo-Brito, EM Soares-Ventura, TJ Marques-Salles, MT Nogueira, MT Muniz, ML Silva, F Hunstig, T Liehr, N Santos.
Identification of a de novo inv dup(X)(pter->q22) by multicolor banding in a girl with Turner syndrome.
Genet Mol Res 2010, 9:780-784. 		1.013 CG
332
 		E Manolakis, P Peitsidis, M Elefteriades, E Dedoulis, M Ziegler, S Orru, T Liehr, MB Petersen.
Prenatal detection of full monosomy 21 in a fetus with an increased nuchal translucency. Molecular cytogenetic analysis and review of the literature.
J Obstet Gynaecol Res 2010, 36:435–440. 		0.440 CG
331
 		T Liehr.
Cytogenetic contribution to uniparental disomy (UPD).
Mol Cytogenet 2010, 3:8. 		n.a. UPD
330
 		VA Trifonov, N Kosyakova, SA Romanenko, AS Graphodatsky, T Liehr.
New insights into the karyotypic evolution in muroid rodents revealed by multicolor banding applying murine probes.
Chr Res 2010, 18:265–275.  		3.130 EVO
329
 		A Weise, B Timmermann, M Grabherr, M Werber, P Heyn, N Kosyakova, T Liehr, H Neitzel, K Konrat, C Bommer, C Dietrich, A Rajab, R Reinhardt, S Mundlos, TH Lindner, K Hoffmann.
High-throughput sequencing of microdissected chromosomal regions.
Eur J Hum Genet 2010, 18:457–462.		 4.380 M
328
 		W Al Achkar, A Wafa, H Mkrtchyan, F Moassas, T Liehr.
A rare case of chronic myeloid leukemia with secondary chromosomal changes including partial trisomy 17q21 to 17qter and partial monosomy of 16p13.3.
Mol Cytogenet 2010, 3:6.  		4.380 TCG
327
 		H Mkrtchyan, M Gross, S Hinreiner, A Polytiko, M Manvelyan, K Mrasek, N Kosyakova, E Ewers, H Nelle, T Liehr, M Volleth, A Weise.
Early embryonic chromosome instability results in stable mosaic pattern in human tissues.
PLoS ONE 2010, 5:e9591. 		4.411 CG
326
 		A Polityko, O Khurs, N Rumyantseva, I Naumchik, N Kosyakova, H Tönnies, K Sperling, H Neitzel, A Weise, T Liehr.
Two siblings with immunodeficiency, facial abnormalities and chromosomal instability without mutation in DNMT3B gene but liability towards malignancy; a new chromatin disorder delineation?
Mol Cytogenet 2010, 3:5 .		 n.a. CG
325
 		K Mrasek, C Schoder, AC Teichmann, K Behr, B Franze, K Wilhelm, N Blaurock, U Claussen, T Liehr, A Weise.
Global screening and extended nomenclature for 230 aphidicolin-inducible fragile sites, including 61 yet unreported ones.
Int J Oncol 2010, 36:929-940. 		2.571 INT
CG
324
 		JC Barber, D Bunyan, M Curtis, D Robinson, S Morlot, A Dermitzel, T Liehr, C Alves, J Trindade, AI Paramos, C Cooper, K Ocraft, E Taylor, VK Maloney.
8p23.1 duplication syndrome differentiated from copy number variation of the defensin cluster at prenatal diagnosis in four new families.
Mol Cytogenet 2010, 3:3. 		n.a. CG
323
 		H Mkrtchyan, DR Garcia Ney, ES de Ventura, T Liehr, GR Felix, T de Jesus Marques-Salles, E Abdelhay, ML Macedo Silva.
Molecular cytogenetic studies characterize near-triploid complex karyotype in a child with acute lymphoblastic leukemia.
Cancer Genet Cytogenet 2010, 197:71-74.		 1.551 TCG
322
 		C Schoder, T Liehr, E Velleuer, K Wilhelm, N Blaurock, A Weise, K Mrasek.
New aspects on chromosomal instability: Chromosomal break-points in Fanconi anemia patients co-localize on the molecular level with fragile sites.
Int J Oncol 2010, 36:307-312. 		2.571 INT
321
 		FE da Silva, AB Cordeiro, CY Nagamachi, JC Pieczarka, W Rens, A Weise, T Liehr, H Mkrtchyan, NP Anselmo, EHC de Oliveira.
A case of aggressive medulloblastoma with multiple recurrent chromosomal alterations.
Cancer Genet Cytogenet 2010; 196:198-200.
 2.571 TCG
78% of publications of Institute of Human Genetics Jena in the actual year


2009
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
320
 		T Liehr.
PWG: Marker chromosomes.
ECA newsletter 2009, 25:23.		 n.a. sSMC
319
 		A Weise, T Liehr, B Fritz, K Schubert, S Neubauer.
Überarbeitung der Leitlinie Molekularzytogenetische Labordiagnostik.
Med Genetik 2009, 21:539-542. 		n.a. other
318
 		T Liehr.
PWG: Marker chromosomes; Permanent working groups (PWGs) report of ECA meeting 2009.
ECA newsletter 2009, 24:9-10.		 n.a. sSMC
317
 		J Barber, T Liehr.
Molecular Cytogenetics; a new open access journal.
ECA-Newsletter, 2009, 24:41.		 n.a. others
316
 		T Liehr.
In memoriam Prof. Dr. med. Uwe Claussen (* 30.04.1945 † 20.07.2008).
ECA-Newsletter 2009, 23:33. 		n.a. others
315
 		T Liehr, J Crolla.
Announcement of the permanent working group (PWG) Marker chromosomes meeting.
ECA-Newsletter 2009, 23:31.		 n.a. sSMC
314
 		H Mkrtchyan, S Scheler, I Klein, A Fahr, P-O Couraud, IA Romero, B Weksler, T Liehr.
Molecular cytogenetic characterization of the human cerebral microvessel endothelial cell line hCMEC/D3.
Cytogenet Genome Res 2009, 126:313-317.		 1.729 CG
313
 		A Polityko, O Khurs, T Liehr.
Human genomic disorders. Analysis of 22q11.
Proceedings of the Institute of Genetics and Cytology of National Academy of Sciences Belarus, Minsk, Special issue „Molecular and applied genetics“ 2009, 10:80-88 (in Russian).		 n.a. CG
312
 		Y Soysal, S Balci, K Hekimler, T Liehr, E Ewers, J Schoumans, TH Bui, FM Içduygu, N Kosyakova, N Imirzalıoğlu.
Characterization of double ring chromosome 4 mosaicism associated with bilateral hip dislocation, cortical dysgenesis, and epilepsy.
Am J Med Gen A 2009, 149A:2782-2787.		 2.404 CG
311
 		F Sheth, E Ewers, N Kosyakova, A Weise, J Sheth, M Desai, J Andrieux, J Vermeesch, AB Hamid, M Ziegler, T Liehr.
A small supernumerary marker chromosome present in a Turner syndrome patient not derived from X- or Y-chromosome.
Mol Cytogenet 2009, 2:22.		 n.a. sSMC
310
 		W Al Achkar, A Wafa, H Mkrtchyan, F Moassass, T Liehr.
Novel complex translocation involving 5 different chromosomes in a chronic myeloid leukemia with Philadelphia chromosome: a case report.
Mol Cytogenet 2009, 2:21.		 n.a. TCG
309
 		T Liehr.
Small supernumerary marker chromosomes (sSMC) – a spotlight on some nomenclature problems.
J Histochem Cytochem 2009, 57:991-993.		 2.372 sSMC
308
 		JB Melo, E Matoso, A Polityko, J Saraiva, L Backx, JR Vermeesch, N Kosyakova, E Ewers, T Liehr, IM Carreira.
Molecular cytogenetic characterization of two cases with a small supernumerary marker chromosome derived from chromosome 16: Towards a genotype/phenotype correlation.
Cytogenet Genome Res 2009, 125:109-114.		 1.729 sSMC
307
 		F Sheth, E Ewers, N Kosyakova, A Weise, J Sheth, S Patil, M Ziegler, T Liehr.
A neocentric isochromosome Yp present as additional small supernumerary marker chromosome – evidence against U-type exchange mechanism?
Cytogenet Genome Res 2009, 125:115-116.		 1.729 sSMC
306
 		E Manolakis, A Vetro, S Kitmirides, I Papoulidis, N Kosyakova, K Mrasek, A Weise, E Agapitos, S Orru, P Peitsidis, T Liehr, MB Petersen.
Prenatal diagnosis, of a fetus with ring chromosome 15 characterized by array-CGH.
Prenat Diag 2009, 29:884-888.		 1.707 CG
305
 		A Faria de Figueiredo, H Mkrtchyan, T Liehr, EM Soares Ventura, T de Jesus Marques-Salles, N Santos, R Corrêa Ribeiro, E Abdelhay, ML Macedo Silva.
A case of childhood acute myeloid leukemia AML (M5) with a neocentric chromosome neo(1)(qter->q23~24::q23~24->qter) and tetrasomy 8 and 21.
Cancer Genet Cytogenet 2009, 193:123-126. 		1.537 TCG
304
 		M Manvelyan, P Kempf, A Weise, K Mrasek, A Heller, A Lier, K Höffken, H-J Fricke, HG Sayer, T Liehr, H Mkrtchyan.
Preferred co-localization of chromosome 8 and 21 in myeloid bone marrow cells detected by three dimensional molecular cytogenetics.
Int J Mol Med 2009, 24:335-341. 		1.980 TCG
INT
303
 		AD Polityko, OM Khurs, AI Kulpanovich, KA Mosse, AV Solntsava, NV Rumyantseva, IV Naumchik, T Liehr, A Weise, H Mkrtchyan.
Paternally derived der(7)t(Y;7)(p11.1~11.2;p22.3)dn in a mosaic case with Turner syndrome.
Europ J Med Gen 2009, 52:207–210.		 1.568 CG
302
 		E Ergul, T Liehr, K Mrasek, A Sazci.
A de novo complex chromosome rearrangement involving three chromosomes (2, 13, and 18) in an oligospermic male.
Fertil Steril 2009, 92:391.e9-391.e12.		 3.970 CG
301
 		L Uroz, T Liehr, K Mrasek, C Templado.
Centromere-specific multicolour fluorescence in situ hybridization on human spermatocyte I and II metaphases.
Hum Reprod 2009, 24:2029-2033. 		3.859 CG
300
 		D Aktas, A Weise, E Utine, D Alehan, K Mrasek, F v Eggeling, H Thieme, E Tuncbilek, T Liehr.
Clinically abnormal case with paternally derived partial trisomy 8p23.3 to 8p12 including maternal isodisomy of 8p23.3: a case report.
Mol Cytogenet 2009, 2:14 . 		3.705 CG
UPD
299
 		A Weise, K Mrasek, E Ewers, H Mkrtchyan, N Kosyakova, T Liehr.
Diagnostic applications of fluorescence in situ hybridization.
Expert Opin Med Diagn 2009, 3:453-460.		 3.705 M
298
 		IY Iourov, SG Vorsanova, T Liehr, AD Kolotii, YB Yurov.
Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain.
Hum Mol Genet 2009, 18:2656-2669.		 7.386 INT
CG
297
 		A Tzschach, C Ramel, A Kron, B Seipel, C Wüster, U Cordes, T Liehr, M Hoeltzenbein, C Menzel, HH Ropers, R Ullmann, V Kalscheuer, J Decker, D Steinberger.
Hypergonadotropic hypogonadism in a patient with inv ins (2;4).
 Int J Androl 2009, 32:226-230. 		3.705 CG
296
 		J Erlecke, I Hartmann, M Hoffmann, T Kroll, H Starke, A Heller, A Gloria, HG Sayer, T Johannes, U Claussen, T Liehr, IF Loncarevic.
Automated detection of residual cells after sex-mismatched stem-cell transplantation - evidence for presence of disease-marker negative residual cells.
Mol Cytogenet 2009, 2:12. 		n.a. CG
M
295
 		T Liehr, E Ewers, N Kosyakova, V Klaschka, F Rietz, R Wagner, A Weise.
Handling small supernumerary marker chromosomes in prenatal diagnostics.
Expert Rev Mol Diagn 2009, 9:317-324.		 3.693 sSMC
294
 		IY Iourov, SG Vorsanova, T Liehr, YB Yurov.
Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: differential expression and pathological meaning.
Neurobiol Dis 2009, 34:212–220.		 4.518 CG
293
 		T Liehr, M Stumm, R-D Wegner, S Bhatt, P Hickmann, PC Patsalis, M Meins, S Morlot, V Klaschka, E Ewers, S Hinreiner, K Mrasek, N Kosyakova, WW Cai, SW Cheung, A Weise.
10p11.2 to 10q11.2 is a yet unreported region leading to unbalanced chromosomal abnormalities without phenotypic consequences.
Cytogenet Genome Res 2009, 24:102-105.		 1.729 HET
292
 		AP Cordeiro, FPE da Silva, JC Pieczarka, CY Nagamachi, NP Anselmo, JR Brito, DS Vasconcelos, T Liehr, A Weise, EHC de Oliveira.
Comparative analysis of proliferative and genetic alterations in a primary chordoid meningioma and its recurrent case using locus-specific probes and AgNOR.
Mol Med Rep 2009, 2:449-454.  		0.220 TCG
291
 		H Aurich, M Sgodda, P Kaltwaßer, M Vetter, A Weise, T Liehr, M Brulport, JG Hengstler, MM Dollinger, WE Fleig, B Christ.
Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo.
Gut 2009, 58:570-5811. 		9.357 CG
290
 		B Auber, V Bruemmer, B Zoll, P Burfeind, D Boehm, T Liehr, K Brockmann, E Willichowski, L Argyriou, I Bartels.
Identification of subtelomeric genomic imbalances and breakpoint mapping with quantitative PCR in 296 individuals with congenital defects and/or mental retardation.
Mol Cytogenet 2009, 2:10.		 n.a. CG
M
289
 		ML Macedo Silva, M do Socorro Pombo-de-Oliveira, SC Raimondi, T Liehr, E Abdelhay, A Faria de Figueiredo, M Tavares de Souza, D Ribeiro Ney Garcia, E Maria Soares de Ventura, A Martins de Sousa, H Mkrtchyan.
Unbalanced chromosome 1 abnormalities in four infants with Down syndrome and acute megakaryocytic leukemia.
Mol Cytogenet 2009, 2:7.		 n.a. TCG
288
 		T de Jesus Marques-Salles, T Liehr, H Mkrtchyan, SC Raimondi, M Tavares de Souza, A Faria de Figueiredo, S Rouxinol, FC Jordy Macedo, E Abdelhay, N Santos, ML Macedo Silva.
A new chromosomal three-way rearrangement involving MLL masked by a t(9;19)(p11;p13) in an infant with acute myeloid leukemia FAB-M5.
Cancer Genet Cytogenet 2009, 189:59-62. 		1.537 TCG
287
 		N Kosyakova, A Weise, K Mrasek, U Claussen, T Liehr, H Nelle.
The hierarchically organized splitting of chromosomal bands for all human chromosomes.
Mol Cytogenet 2009, 2:4.  		n.a. INT
286
 		M Gross, H Mkrtchyan, M Glaser, HJ Fricke, K Höffken, A Heller, A Weise, T Liehr.
Delineation of yet unknown cryptic subtelomere aberrations in 50% of acute myeloid leukemia with normal GTG-banding karyotype.
Int J Oncol 2009, 34:417-423.  		2.447 TCG
285
 		S Kitsiou-Tzeli, E Manolakos, M Lagou, K Anagnostopoulou, M Kontodiou, N Kosyakova, E Ewers, A Weise, A Garas, S Orru, T Liehr, A Metaxotou.
Characterization of a prenatally assessed de novo supernumerary minute ring chromosome 20 in a phenotypically normal male.
Mol Cytogenet 2009, 2:8.  		n.a. sSMC
284
 		T Liehr.
The internet page on small supernumerary marker chromosomes (sSMC).
ECA Newsletter 2009, 23:10-14. 		n.a. sSMC
283
 		S Bhatt, K Moradkhani, K Mrasek, J Puechberty, M Manvelyan, F Hunstig, G Lefort, A Weise, J Lespinasse, P Sarda, T Liehr, S Hamamah, F Pellestor.
Breakpoint mapping and complete analysis of meiotic segregation patterns in three men heterozygous for paracentric inversions.
Eur J Hum Genet 2009, 17:44–50.
 		3.564 CG
62% of publications of Institute of Human Genetics Jena in the actual year


2008  
Number
 		  Authors/ Title/ Where Contribution was Published
 		Impact Factor
Topic
282
 		T Liehr, F v Eggeling.
In memoriam Professor Dr. Uwe Claussen (*30.04.1945, † 20.07.2008).
Ärtzeblatt Thüringen 2008, 9:494-495.
 		n.a.
 		other
281
 		T Liehr, R-D Wegner, M Stumm, G Joksi, A Polityko, N Kosyakova, E Ewers, D Reich, R Wagner, A Weise.
Pallister-Killian syndrome. Rare phenotypic features and variable karyotypes.
Balk J Med Gen 2008, 11:65-67. 
n.a.
sSMC
280
 		GG Hovhannisyan, H Mkrtchyan, T Liehr, R Aroutiounian.
Distribution of the chromosomes X, 7 and 18 in mitomycin C induced micronuclei.
Balk J Med Gen 2008, 11:45-49. 
n.a.
CG
279
 		T Liehr.
Multicolor-fluorescence in situ hybridization - Molecular cytogenetics in nowadays diagnostics and research.
Med Gen 2008, 20:374-378 (German).
n.a.
M
278
 		M Manvelyan, F Hunstig, S Bhatt, K Mrasek, F Pellestor, A Weise, I Simonyan, R Aroutiounian, T Liehr.
Chromosome distribution in human sperm - a 3D multicolor banding-study.
Mol Cytogent 2008, 1:25.
n.a.
INT
277
 		E Manolakos, N Kosyakova, L Thomaidis, R Neroutsou, A Weise, M Mihalatos, S Orru, H Kokotas, G Kitsos, T Liehr, MB Petersen.
Complex chromosome rearrangement in a child with microcephaly, dysmorphic facial features and mosaicism for a terminal deletion del(18)(q21.32-qter) investigated by FISH and array-CGH: Case report.
Mol Cytogenet 2008, 1:24. 
n.a.
CG
276
 		T Liehr.
The multicolor fluorescence in situ hybridization (mFISH) homepage.
Balk J Med Gen 2008, 11:27-31. 
n.a.
M
275
 		K Mrasek, G Krüger, I Bauer, J Müller-Navia, T Liehr, A Weise.
A new unbalanced chromosomal abnormality in 1q31.1 to 1q32 without phenotypic consequences.
Cytogenet Genome Res 2008, 121:286-287.
 		1.965
HET
274
 		IY Iourov, SG Vorsanova, T Liehr, VV Monakhov, IV Soloviev, YB Yurov.
Dynamic mosaicism manifesting as loss, gain and rearrangement of an isodicentric Y chromosome in a male child with growth retardation and abnormal external genitalia.
Cytogenet Genome Res 2008, 121:302-306. 
1.965
CG
273
 		J Lian, Y Yin, M Oliver-Bonet, T Liehr, E Ko, P Turek, F Sun, R H Martin.
Variation in crossover interference levels on individual chromosomes from human males.
Hum Mol Gen 2008, 17:2583-2594. 
7.249
CG
272
 		AD Polityko, GI Lazjuk, T Liehr.
High resolution molecular cytogenetic approaches and study of marker chromsomes.
Medica Genetics 2008, 7:34-40. 
n.a.
sSMC
271
 		A Weise, T Liehr.
Fluorescence in situ hybridization for prenatal screening of chromosomal aneuploidies.
Expert Rev Mol Diagn 2008, 8:355-357. 
3.472
PRE
CG
270
 		SG Vorsanova, IY Iourov, VY Voinova-Ulas, A Weise, VV Monakhov, AD Kolotii, IV Soloviev, PV Novikov, T Liehr, YB Yurov.
Partial monosomy 7q34-qter and 21pter-q22.13 due to cryptic unbalanced translocation t(7;21) but not monosomy of the whole chromosome 21: a case report plus review of the literature.
Mol Cytogenet 2008, 1:13. 
n.a.
CG
269
 		T Pramparo, M de Gregori, S Gimelli, R Ciccone, D Frondizi, T Liehr, S Pellacani, G Masi, P Brovedani, O Zuffardi, R Guerrini.
A 7 Mb duplication at 22q13 in a girl with bipolar disorder and hippocampal malformation.
Am J Med Genet A. 2008, 146A:1754-1760. 
2.555
CG
268
 		H Mkrtchyan, S Ghazaryan, G Avetisyan, A Hovhannisyan, L Muradyan, S Daghbashyan, C Karst, M Gross, S Hinreiner, R Aroutiounian, T Liehr.
Novel complex t(V;9;22) rearrangements in three cases with chronic myeloid leukemia and a rare translocation in a case with classical Philadelphia chromosome.
Oncol Reports 2008, 20:99-104. 
1.524
TCG
267
 		T Liehr, K Mrasek, N Kosyakova, C Mackie Ogilvie, J Vermeesch, V Trifonov, N Rubtsov.
Small supernumerary marker chromosomes (sSMC) in humans. Are there B chromosomes hidden among them?
Mol Cytogenet 2008, 1:12. 
n.a.
sSMC
266
 		M Manvelyan, M Riegel, M Santos, C Fuster, F Pellestor, M-L Mazauric, B Schulze, A Polityko, H Tittelbach, G Reising-Ackermann, B Belitz, U Hehr, C Kelbova, M Volleth, E Gödde, J Anderson, P Küpferling, S Köhler, H-C Duba, A Dufke, D Aktas, T Martin, I Schreyer, E Ewers, D Reich, K Mrasek, A Weise, T Liehr.
32 new cases with small supernumerary marker chromosomes (sSMC) detected in connection with fertility problems – detailed molecular cytogenetic characterization and review of the literature.
Int J Mol Med 2008, 21:705-714. 
1.880
sSMC
265
 		M Manvelyan, F Hunstig, K Mrasek, S Bhatt, F Pellestor, A Weise, T Liehr.
Position of chromosomes 18, 19, 21 and 22 in 3D-preserved interphase nuclei of human and gorilla and white hand gibbon.
Mol Cytogenet 2008, 1:9. 
n.a.
EVO
264
 		A Koç, D Kan, K Karaer, MA Ergün, K Gücüyener, S Hinreiner, T Liehr, EF Perçin.
An unexpected finding in a child with neurological problems: Mosaic Ring Chromosome 18.
Europ J Pediatrics 2008, 167:655–659. 
1.416
CG
263
 		A Weise, K Mrasek, I Fickelscher, U Claussen, SW Cheung, WW Cai, T Liehr, N Kosyakova.
Molecular definition of high resolution multicolor banding (MCB) probes – first within the human DNA-sequence anchored FISH-banding probe set.
J Histochem Cytochem 2008, 56:487-493. 
2.823
M
262
 		V Trifonov, S Fluri, F Binkert, A Nandini, J Andersen, L Rodriguez, M Gross, N Kosyakova, H Mkrtchyan, E Ewers, D Reich, A Weise, T Liehr.
Three new cases of complex rearranged small supernumerary marker chromosomes. Evidence for an underestimated entity?
Mol Cytogenet 2008, 1:6.   
n.a.
sSMC
261
 		L Rodriguez, T Liehr, ML Martinez-Fernandez, A Lara, A Torres, ML Martinez-Frias.
A new small supernumerary marker chromosome, generating mosaic pure trisomy 16q11.1-q12.1 in a healthy man.
Mol Cytogenet 2008, 1:4. 
n.a.
sSMC
260
 		YB Yurov, T Liehr, LG Shaffer, IY Iourov, SG Vorsanova.
A new open access journal for a rapidly evolving biomedical field: introducing Molecular Cytogenetics.
Mol Cytogenet 2008, 1:1. 
n.a.
other
259
 		MLM Silva, SC Raimondi, E Abdelhay, M Gross, H Mkrtchyan, A F de Figueiredo, RC Ribeiro, TdJ Marques-Salles, ES Sobral, MPG Land, T Liehr.
Banding and molecular cytogenetic studies detected a CBFß-MYH11 fusion gene that appeared as abnormal chromosomes 1 and 16 in a baby with acute myeloid leukemia FAB M4-Eo.
Cancer Genet Cytogenet 2008, 182:56-60. 
1.482
TCG
258
 		A Weise, M Gross, K Mrasek, H Mkrtchyan, B Horsthemke, C Jonsrud, F von Eggeling, S Hinreiner, V Witthuhn, U Claussen, T Liehr.
Parental-origin-determination fluorescence in situ hybridization distinguishes homologous human chromosomes on a single-cell level.
Int J Mol Med 2008, 21:189-200. 
1.880
M
UPD
257
 		I Balikova, K Martens, C Melotte, M Amyere, S Van Vooren, Y Moreau, D Vetrie, H Fiegler, NP Carter, T Liehr, M Vikkula, G Matthijs, JP Fryns, I Casteels, K Devriendt, JR Vermeesch.
Autosomal-dominant microtia linked to five tandem copies of a copy-number-variable region at chromosome 4p16.
Am J Hum Genet 2008, 82:181-187.  
10.153
CG
256
 		YB Yurov, IY Iourov, SG Vorsanova, IA Demidova, VS Kravetz, AK Beresheva, AD Kolotii, VV Monakhov, NA Uranova, VM Vostrikov, IV Soloviev, T Liehr.
The schizophrenia brain exhibits low-level mosaic aneuploidy involving chromosome 1.
Schizophr Res 2008, 98:139-147. 
4.174
CG
INT
56% of publications of Institute of Human Genetics Jena in the actual year


2007
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
255
 		T Liehr, A Weise.
Neuer Ansatz zum Studium epigenetischer Veränderungen bei der akuten myeloischen Leukämie.
Leukämie Rundbrief 2007, 11:8-9. 		n.a. TCG
254
 		T Liehr.
PWG: Marker chromosomes; Permanent working groups (PWGs) report of ECA meeting 2007.
ECA newsletter 2007, 20:8-9. 		n.a. sSMC
253
 		T Liehr, H Tönnies, L Rodriguez, M Hulten.
Supernumerary Ring 1.
Leaflet published in 2007 by UNIQUE, Rare Chromosome Disorder Support Group 		n.a. sSMC
252
 		T Liehr.
Small supernumerary marker chromosomes.
Leaflet published in 2007 by UNIQUE, Rare Chromosome Disorder Support Group 		n.a. sSMC
251
 		T Liehr, J Crolla.
Announcement of the new permanent working group (PWG) Marker chromosomes.
ECA newsletter 2007, 19:31.		 n.a. sSMC
250
 		T Liehr, K Mrasek, S Hinreiner, D Reich, E Ewers, I Bartels, J Seidel, E Manolakos, M Petersen, A Polityko, A Dufke, I Iourov, V Trifonov, J Vermeesch, A Weise.
Small supernumerary marker chromosomes (sSMC) in patients with a karyotype 45,X/46,X,+mar – 17 new cases and a review of the literature.
Sex Dev 2007, 1:353-362.  		n.a. sSMC
249
 		F Sun, M Oliver-Bonet, T Liehr, H Starke, E Ko, A Rademaker, RH Martin.
Discontinuities and unsynapsed regions in meiotic chromosomes have a trans effect on meiotic recombination of some chromosomes in human males.
Cytogenet Genome Res 2007, 119:27-32.  		2.402 CG
248
 		T Felka, J Lemke, C Lemke, S Michel, T Liehr, U Claussen.
DNA degradation during maturation of erythrocytes—molecular cytogenetic characterization of Howell–Jolly bodies.
Cytogenet Genome Res 2007, 119:2-8.  		2.402 CG
247
 		NP Bochkov, ES Voronina, NV Kosyakova, T Liehr, AA Rzhaninova, LD Katosova, VI Platonova, DV Goldshtein.
Chromosome variability of human multipotent mesenchymal stromal cells.
Bull Exp Biol Med 2007, 143:122-126. – also in Kletochnye Tehnologii v Biologii i Medicine 2007, 1:11-15 (in Russian) . 		n.a. CG
246
 		M Santos, K Mrasek, MA Rigola, H Starke, T Liehr, C Fuster.
Identification of a “cryptic mosaicism” involving at least 4 different small supernumerary markers, derived from chromosome 9, in a woman without reproductive success.
Fertil Steril 2007, 88:969.e11-7. 		3.168 sSMC
245
 		I Carreira, A Mascarenhas, E Matoso, A Couceiro, L Ramos, A Dufke, M Mazauric, R Stressig, N Kosyakova, J Melo, T Liehr.
Three unusual but cytogenetically similar cases with up to five different cell lines involving structural and numerical abnormalities of chromosome 18.
J Histochem Cytochem 2007, 55:1123-1128.  		2.335 CG
244
 		L Rodríguez, T Liehr, K Mrasek, E Mansilla, ML Martínez-Fernández, G Ángel, ML Martínez-Frías.
First inherited small supernumerary chromosome marker generating complete trisomy 18p, characterized by molecular cytogenetic techniques and review.
Am J Med Gen A 2007, 143:2727-2732.  		2.440 sSMC
243
 		S Bhatt, K Moradkhani, K Mrasek, J Puechberty, G Lefort, J Lespinasse, P Sarda, T Liehr, S Hamamah, F Pellestor.
Breakpoint characterization: a new approach for segregation analysis of paracentric inversion in human sperm.
Mol Hum Reprod 2007, 13:751-756.  		2.871 CG
242
 		T Liehr, GE Utine, U Trautmann, A Rauch, A Kuechler, J Pietrzak, E Bocian, N Kosyakova, K Mrasek, K Boduroglu, A Weise, D Aktas.
Neocentric small supernumerary marker chromosomes (sSMC) - three more cases plus review of the literature.
Cytogenet Genome Res 2007, 118:31-37. 		2.402 sSMC
241
 		IY Iourov, T Liehr, SG Vorsanova, YB Yurov.
Interphase chromosome-specific multicolor banding (ICS-MCB): a new tool for analysis of interphase chromosomes in their integrity.
Biomolecul Engineer 2007, 24:415-417.  		4.246 INT
M
240
 		I Fickelscher, T Liehr, K Watts, V Bryant, JCK Barber, R Siebert, S Heidemann, JM Hertz, Z Tümer, NS Thomas.
The variant inv(2)(p11.2q13) is a genuinely recurrent rearrangement but displays some breakpoint heterogeneity.
Am J Hum Gen 2007, 81:847-856.  		11.092 HET
239
 		GE Utine, D Aktas, Y Alanay, S Gücer, E Tuncbilek, K Mrasek, T Liehr.
Distal partial trisomy 1q: report of two cases and a review of the literature.
Prenat Diagn 2007, 27:865-871 . 		1.319 CG
238
 		J Mattes, B Whitehead, T Liehr, I Wilkinson, J Bear, K Fagan, P Craven, B Bennett, M Edwards.
Paternal uniparental isodisomy for chromosome 14 with a mosaicism for a supernumerary marker chromosome 14.
Am J Med Gen A 2007, 143A:2165-2171.  		2.440 sSMC
237
 		I Fickelscher, H Starke, E Schulze, G Ernst, N Kosyakova, H Mkrtchyan, K MacDermont, N Sebire, T Liehr.
A further case with a small supernumerary marker chromosome (sSMC) derived from chromosome 1 – evidence for high variability in mosaicism in different tissues of sSMC-carriers.
Prenat Diagn 2007, 27:783-785.  		1.319 sSMC
236
 		T Liehr, V Trifonov, A Polityko, L Brecevic, K Mrasek, A Weise, E Ewers, D Reich, I Iourov, H Mkrtchyan, M Manvelyan, N Kosyakova.
Characterization of small supernumerary marker chromosomes (sSMC) by a simple molecular and molecular cytogenetics approach.
Balk J Med Gen 2007, 10:33-37. 		n.a. sSMC
235
 		A Serra, HK Schackert, B Mohr, A Weise, T Liehr, G Fitze.
t(11;19)(q21;p12 ~ p13.11) and MECT1-MAML2 fusion transcript expression as a prognostic marker in infantile lung mucoepidermoid carcinoma.
J Pediatr Surg 2007, 42:e23-29.  		1.227 TCG
234
 		YB Yurov, IY Iourov, SG Vorsanova, T Liehr, AD Kolotii, SI Kutsev, F Pellestor, AK Beresheva, IA Demidova, VS Kravets, VV Monakhov, IV Soloviev.
Aneuploidy and confined chromosomal mosaicism in the developing human brain.
PLoS ONE 2007, 2:e558.  		n.a. INT
233
 		J Rosenhahn, A Weise, S Michel, K Hennig, I Hartmann, J Schiefner, K Schubert, T Liehr, F v Eggeling, IF Loncarevic.
Cytogenetic characterisation and proteomic profiling of the Imatinib-resistant cell line KCL22-R.
Int J Onc 2007, 31:121-128.  		2.295 TCG
232
 		H Tönnies, J Pietrzak, E Bocian, K MacDermont, A Kuechler, B Belitz, U Trautmann, A Schmidt, B Schulze, L Rodríguez, F Binkert, C Yardin, N Kosyakova, M Volleth, H Mkrtchyan, I Schreyer, F von Eggeling, A Weise, K Mrasek, T Liehr.
16 new immortalized cell lines of patients with small supernumerary marker chromosome (sSMC) – towards the establishment of a cell bank.
J Histochem Cytochem 2007, 55:651-660. 		2.335 sSMC
231
 		J Pietrzak, K Mrasek, E Obersztyn, P Stankiewicz, N Kosyakova, A Weise, SW Cheung, WW Cai, F von Eggeling, T Mazurczak, E Bocian, T Liehr.
Molecular cytogenetic characterization of eight supernumerary marker chromosomes (sSMC) originating from chromosomes 2, 4, 8, 18, and 21 in three patients.
J Appl Genet 2007, 48:167-175.  		0.967 sSMC
230
 		M Manvelyan, I Schreyer, I Höls-Herpertz, S Köhler, R Niemann, U Hehr, B Belitz, I Bartels, J Götz, D Huhle, M Kossakiewicz, H Tittelbach, S Neubauer, A Polityko, M-L Mazauric, R Wegner, M Stumm, P Küpferling, F Süss, H Kunze, A Weise, T Liehr, K Mrasek.
48 new cases with infertility due to balanced chromosomal rearrangements  – detailed molecular cytogenetic analysis of the 90 involved breakpoints.
Int J Mol Med 2007, 19:855-864.   		1.847 CG
219
 		SM Sauter, D Böhm, I Bartels, P Burfeind, FA Laccone, J Neesen, B Wilken, T Liehr, B Zoll.
Partial trisomy of distal 19q detected by quantitative real-time PCR and FISH in a girl with mild facial dysmorphism, hypotonia and developmental delay.
Am J Med Genet A 2007, 143A:1091-1099.  		2.440 CG
218
 		B Zoll, D Böhm, SM Sauter, T Liehr, R Funke, B Auber, I Bartels, P Burfeind.
Subtelomere Rerrangements. Eine Ursache für geistige Behinderung?
Kinder und Jugendarzt 2007, 38:236-243. 		n.a. CG
217
 		T Liehr, A Weise.
Frequency of small supernumerary marker chromosomes in prenatal, newborn, developmentally retarded and infertility diagnostics.
Int J Mol Med 2007, 19:719-731. 		1.847 sSMC
216
 		I Bartels, H Starke, L Argyriou, SM Sauter, B Zoll, T Liehr.
An exceptional complex chromosomal rearrangement (CCR) with 8 breakpoints involving four chromosomes (1;3;9;14) in an azoospermic male with normal phenotype.
Europ J Med Gen 2007, 50:133-138.  		1.857 CG
215
 		M Glei, A Schaeferhenrich, U Claussen, A Kuechler, T Liehr, A Weise, B Marian, W Sendt, BL Pool-Zobel.
 Comet fluorescence in situ hybridization analysis for oxidative stress-induced DNA damage in colon cancer relevant genes.
Toxicol Sci 2007, 96:279-284.  		3.814 TCG
214
 		L Backx, H Van Esch, C Melotte, N Kosyakova, H Starke, JP Frijns, T Liehr, JR Vermeesch.
Array painting using microdissected chromosomes to map chromosomal breakpoints.
Cytogenet Genome Res 2007, 116:158-166.  		2.402 sSMC
M
213
 		S Balci, A Ünal, D Aktaş, Ö Engiz, T Liehr, M Gross, K Mrasek, S Saygi.
Bilateral periventricular nodular heterotopia (PNH), severe mental retardation and epilepsy in a male patient with 46,XY,der(19)t(X;19)(q11.1-11.2;p13.3) due to maternal balanced translocation.
Develop Med Child Neurol 2007, 49:219-224. 		2.433 CG
212
 		J Seidel, A Hübler, D Schlenvoigt, P Hilliges, M Harbich, A Küchler, T Liehr, U Claussen, E Kauf.
Schwere Wachstumsretardierung bei Deletion des IGF1-Rezeptor-Gens.
Praktische Pädiatrie 2007, 13:1-5.  		n.a. CG
211
 		A Weise, M Gross, S Schmidt, U Claussen, T Liehr.
New aspects of chromosomal evolution in gorilla and orangutan.
Int J Mol Med 2007, 19:437-443. 		1.847 EVO
41% of publications of Institute of Human Genetics Jena in the actual year


2006
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
210
 		J Seidel, H Hübler, A Küchler, M Harbich, P Hilliges, E Kauf, U Claussen, T Liehr.
Genetisch bedingte Wachstumsstörungen: Syndromatischer Kleinwuchs am Beispiel von Falldemonstrationen.
Medreport 2006, 4:9. 		n.a.
 		CG
209
 		E Papadopoulou, S Sifakis, C Sarri, J Gyftodimou, T Liehr, K Mrasek, M Kalmanti, MB Petersen.
A case report of pure 7p duplication syndrome and review of the literature.
Am J Med Gen A 2006, 140A:2802-2806.  		2.063 CG
208
 		F Sun, M Oliver-Bonet, T Liehr, H Starke, P Turek, E Ko, A Rademaker, RH Martin.
Analysis of non-crossover bivalents in pachytene cells from 10 normal male.
Hum Reprod 2006, 21:2335-2339.  		3.769 CG
207
 		D Mitter, K Buiting, F von Eggeling, A Kuechler, T Liehr, UA Mau-Holzmann, EC Prott, D Wieczorek, G Gillessen-Kaesbach.
Is there a higher incidence of maternal uniparental disomy 14 [upd(14)mat]? Detection of 10 new patients by methylation-specific PCR.
Am J Med Genet A 2006, 140A:2039-2049.  		2.063 CG
UPD
206
 		L Brecevic, S Michel, H Starke, K Müller, N Kosyakova, K Mrasek, A Weise, T Liehr.
Multicolor FISH used for the characterization of small supernumerary marker chromosomes (sSMC) in commercially available immortalized cell lines.
Cytogenet Genome Res 2006, 114:319-324.  		1.993 sSMC
205
 		H Mkrtchyan, M Glaser, M Gross, U Wedding, K Höffken, T Liehr, C Karst, R Aroutiounian.
Multicolor-FISH applied to resolve complex chromosomal changes in a case of T-ALL (FAB L2).
Cytogenet Genome Res 2006, 114:270-273. 		1.993 TCG
204
 		T Liehr, H Starke H, A Heller, N Kosyakova, K Mrasek, M Gross, C Karst, U Steinhaeuser, F Hunstig, I Fickelscher, A Kuechler, V Trifonov, SA Romanenko, A Weise.
Multicolor fluorescence in situ hybridization (FISH) applied for FISH-banding.
Cytogenet Genome Res 2006, 114:240-244.  		1.993 M
203
 		T Liehr.
Preface to the special issue Multicolor FISH in Human Cytogenetics.
Cytogenet Genome Res 2006, 114:187-188.  		1.993 M
202
 		T Liehr.
Familial small supernumerary marker chromosomes are predominantly inherited via the maternal line.
Genet Med 2006, 8:459-462.  		3.427 sSMC
201
 		F Sun, M Oliver-Bonet, T Liehr, H Starke, P Turek, E Ko, A Rademaker, RH Martin.
Variation in MLH1 distribution in recombination maps for individual chromosomes from human males.
Hum Mol Genet 2006, 15:2376-2391.  		8.099 CG
200
 		IY Iourov, T Liehr, SG Vorsanova, AD Kolotii, YB Yurov.
Visualization of interphase chromosomes in postmitotic cells of the human brain by multicolour banding (MCB).
Chromosome Res 2006, 14:223-229.   		3.057 CG
INT
199
 		C Karst, M Gross, D Haase, U Wedding, K Höffken, T Liehr, H Mkrtchyan.
Novel cryptic chromosomal rearrangements detected in acute lymphoblastic leukemia (ALL) detected by application of new multicolor fluorescent in situ hybridization approaches.
Int J Onc 2006, 28:891-897. 		2.556 TCG
198
 		C Rudolph, T Liehr, D Steinemann, M Emura, M Daibata, Y Matsuo, N Emi, M Abe, R Lai, K Mrasek, U Claussen, B Schlegelberger.
Different breakage-prone regions on chromosome 1 detected in t(11;14)-positive mantle cell lymphoma cell lines and multiple myeloma cell lines are associated with different tumor progression-related mechanisms.
Cytogenet Genome Res 2006, 112:213-221.  		1.993 TCG
197
 		S Balci, Ö Engiz, D Aktaş, I Vargel, MS Beksaç, K Mrasek, T Liehr.
Ring chromosome 4 and Wolf-Hirschhorn syndrome (WHS) in a child with multiple malformations.
Am J Med Gen 2006, 140A:628-632.  		2.063 CG
196
 		P Stankiewicz, A Kuechler, CD Eller, T Sahoo, C Baldermann, U Lieser, M Hesse, C Gläser, M Hagemann, SA Yatsenko, T Liehr, B Horsthemke, U Claussen, Y Marahrens, JR Lupski, I Hansmann.
Minimal phenotype in a girl with trisomy 15q due to t(X;15)(q22.3;q11.2) translocation - do LINE-1 elements facilitate spreading of X inactivation?
Am J Med Gen 2006, 140A:442-452.  		2.063 CG
195
 		C Karst, V Trifonov, SA Romanenko, U Claussen, K Mrasek, S Michel, P Avner, T Liehr
Molecular cytogenetic characterization of the mouse cell line WMP2 by spectral karyotyping (SKY) and multicolor banding (mcb) applying murine probes.
Int J Mol Med 2006, 17:209-213.  		1.854 TCG
194
 		T Liehr, M Gross, C Karst, M Glaser, H Mkrtchyan, K Mrasek, H Starke, A Kuechler, A Weise.
FISH-banding in tumor cytogenetics.
Cancer Genet Cytogenet 2006, 164:88-89.  		1.544 TCG
193
 		T Liehr, K Mrasek, A Weise, A Dufke, L Rodríguez, N Martínez Guardia, A Sanchís, JR Vermeesch, C Ramel, A Polityko, O Haas, J Anderson, U Claussen, F von Eggeling, H Starke.
Small supernumerary marker chromosomes - progress towards a genotype-phenotype correlation.
Cytogenet Genome Res 2006, 112:23-34.  		1.993 sSMC
192
 		T Liehr, H Starke, G Senger, C Melotte, A Weise, JR Vermeesch.
Overrepresentation of small supernumerary marker chromosomes (sSMC) from chromosome 6 origin in cases with multiple sSMC.
Am J Med Gen 2006, 140A:46-51.  		2.063 sSMC
191
 		M Gross, H Starke, V Trifonov, U Claussen, T Liehr, A Weise.
A molecular cytogenetic study of chromosome evolution in chimpanzee.
Cytogenet Genome Res 2006, 112:67-75.  		1.993 EVO
40% of publications of Institute of Human Genetics Jena in the actual year


2005
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
190
 		T Liehr.
Eine erste Genotyp-Phänotyp-Korrelation bei kleinen überzähligen Marker-Chromosomen (small supernumerary marker chromosomes = sSMC) des Menschen.
Medgen 2005, 17:454-456. 		n.a. sSMC
189
 		M Glaser, C Karst, M Gross, H Mkrtchyan, T Liehr.
Chromosome torsions in cytogenetic preparations of bone-marrow – artifacts or leukemia-specific?
Balk J Med Gen 2005, 8:27-31. 		n.a. TCG
188
 		F Sun, M Oliver-Bonet, T Liehr, H Starke, K Trpkov, E Ko, A Rademaker, R H Martin.
Discontinuities and unsynapsed regions in meiotic chromosomes have a cis effect on meiotic recombination patterns in normal human males.
Human Molecular Genetics 2005, 14:3013-3018.  		7.764 CG
187
 		T Kautenburger, G Beyer-Sehlmeyer, G Festag, N Haag, S Kuhler, A Kuchler, A Weise, B Marian, WH Peters, T Liehr, U Claussen, BL Pool-Zobel.
The gut fermentation product butyrate, a chemopreventive agent, suppresses glutathione S-transferase theta (hGSTT1) and cell growth more in human colon adenoma (LT97) than tumor (HT29) cells.
J Cancer Res Clin Oncol 2005, 131:692-700.  		2.503 TCG
186
 		C Gutiérrez-Mateo, J Benet, H Starke, M Oliver-Bonet, S Munné, T Liehr, J Navarro.
Karyotyping of human oocytes by cenM-FISH, a new 24-colour centromere-specific technique.
Hum Reprod 2005, 20:3395-3401.  		3.669 CG
185
 		A Weise, T Liehr, U Claussen, K-J Halbhuber.
Increased efficiency of fluorescence in situ hybridization (FISH) using the microwave.
J Histochem Cytochem 2005, 53:1301-1303.  		2.208 M
184
 		JC Barber, V Maloney, EJ Hollox, A Stuke-Sontheimer, G du Bois, E Daumiller, U Klein-Vogler, A Dufke, JA Armour, T Liehr.
Duplications and copy number variants of 8p23.1 are cytogenetically indistinguishable but distinct at the molecular level.
Eur J Hum Genet 2005, 13:1131-1136.  		3.251 CG
183
 		JR Vermeesch, C Melotte, I Salden, M Riegel, V Trifnov, A Polityko, N Rumyantseva, I Naumchik, H Starke, G Matthijs, A Schinzel, JP Fryns, T Liehr.
Tetrasomy 12pter-12p13.31 in a girl with partial Pallister-Killian syndrome phenotype.
Eur J Med Genet 2005, 48:319-327.  		0.625 sSMC
182
 		T Pramparo, T Mattina, S Gimelli, T Liehr, O Zuffardi.
Narrowing the deleted region associated with the 15q21 syndrome.
Europ J Med Gen 2005, 48:346-352.  		0.625 CG
181
 		L Rodriguez, H Starke, NM Guardia, H Tönnies, H Neitzel, P Kozlowski, ML Mazauric, A Heller, FL Grondona, E Mansilla, MJ Santos Munoz, T Liehr, ML Martinez-Frias.
Three new cases with a supernumerary ring chromosome 1.
Clin Dysmorphol 2005, 14:169-175.  		0.667 sSMC
180
 		T Liehr, K Mrasek, H Starke, U Claussen, G Schreiber.
Unusual small supernumerary marker chromosome (sSMC) 9 in a Klinefelter patient.
Cytogenet Genome Res 2005, 111:179-181.  		2.076 sSMC
179
 		A Polityko, H Starke, N Rumyantseva, U Claussen, T Liehr, S Raskin.
Three cases with rare interstitial rearrangements of chromosome 1 characterized by multicolor banding.
Cytogenet Genome Res 2005, 111:171-174.  		2.076 CG
178
 		ML Macedo Silva, M Land, A Heller, E Abdelhay, M do Socorro Pombo-de-Oliveira, K Ribeiro, G Alves, D Lerner, T Liehr.
New rearrangement t(3;17)(q26.3;q12) in an AML patient with a poor outcome.
Oncol Rep 2005, 14:663-666.  		1.572 TCG
177
 		G von Beust, SM Sauter, T Liehr, P Burfeind, I Bartels, H Starke, F von Eggeling, B Zoll.
Molecular cytogenetic characterization of a de novo supernumerary ring chromosome 7 resulting in partial trisomy, tetrasomy, and hexasomy in a child with dysmorphic signs, congenital heart defect, and developmental delay.
Am J Med Gen 2005, 137:59-64. 		1.913 sSMC
176
 		C Karst, A Heller, U Claussen, E Gebhart, T Liehr.
Detection of cryptic chromosomal aberrations in the in vitro non-proliferating cells of acute myeloid leukemia.
Int J Oncol 2005, 27:355-359.  		2.681 TCG
175
 		S Schmidt, U Claussen, T Liehr, A Weise.
Evolution versus constitution: Differences in chromosomal inversion.
Hum Genet 2005, 117:213-219.  		4.331 EVO
174
 		V Trifonov, C Karst, U Claussen, K Mrasek, S Michel, P Avner, T Liehr.
Microdissection derived murine mcb probes from somatic cell hybrids.
J Histochem Cytochem 2005, 53:791-792.  		2.208 M
173
 		T Liehr, E Brude, G Gillessen-Kaesbach, R König, K Mrasek, F von Eggeling, H Starke.
Prader-Willi syndrome with a karyotype 47,XY,+min(15)(pter->q11.1:) and maternal UPD 15 - case report plus review of similar cases.
Europ J Med Genet 2005, 48:175-181.  		1.614 sSMC
UPD
172
 		A Kuechler, M Ziegler, C Blank, B Rommel, J Bullerdiek, J Ahrens, U Claussen, T Liehr.
A highly complex chromosomal rearrangement between five chromosomes in a healthy female diagnosed in preparation for ICSI.
J Histochem Cytochem 2005, 53:355-357. 		2.208 CG
171
 		T Liehr, M Ziegler.
Rapid prenatal diagnostics in the interphase nucleus – procedure and cut-off rates.
J Histochem Cytochem 2005, 53:289-291.  		2.208 PRE
CG
170
 		M Trimborn, T Liehr, B Belitz, L Pfeiffer, R Varon, H Neitzel, H Tönnies.
Prenatal diagnosis and molecular cytogenetic characterisation of a complex structural rearrangement in a pregnancy following intracytoplasmic sperm injection (ICSI).
J Histochem Cytochem 2005, 53:351-354.  		2.208 CG
169
 		H Starke, K Mrasek, T Liehr.
3 cases with enlarged acrocentric p-arms – 2 cases with cryptic partial trisomies.
J Histochem Cytochem 2005, 53:359-360.  		2.208 CG
HET
168
 		I Schreyer, A Neumann, V Beensen, K-H Eichhorn, A Heller, U Claussen, T Liehr.
dup(13)(q14.2-q14.3) - yet another new differential diagnostic aspect for short stature like phenotype.
J Histochem Cytochem 2005, 53:365-366.  		2.208 CG
167
 		K Mrasek, H Starke, T Liehr.
Another small supernumerary marker chromosome (sSMC) derived from chromosome 2 – towards a genotype/ phenotype correlation.
J Histochem Cytochem 2005, 53:367-370.  		2.208 sSMC
166
 		T Liehr, H-UG Weier.
14th Workshop on Fetal Cells and Fetal DNA.
J Histochem. Cytochem 2005, 53:253-254.  		2.208 CG
165
 		JCK Barber, NS Thomas, MN Collinson, NR Dennis, T Liehr, A Weise, B Belitz, L Pfeiffer, M Kirchhoff, B Krag-Olsen, C Lundsteen.
Segmental haplosufficiency: transmitted deletions of 2p12 include a pancreatic regeneration gene cluster and have no apparent phenotypic consequences.
Europ J Hum Gen 2005, 13:283-291.  		3.251 CG
164
 		M Oliver-Bonet, J Benet, F Sun, J Navarro, C Abad, T Liehr, H Starke, C Greene, E Ko, RH Martin.
Meiotic studies in two human reciprocal translocations and their association with spermatogenic failure.
Human Reproduction 2005, 20:683-688.  		3.669 CG
163
 		A Weise, H Starke, K Mrasek, U Claussen, T Liehr.
New insights into the evolution of chromosome 1.
Cytogenet Genome Res 2005, 108:217-222.  		2.076 EVO
56% of publications of Institute of Human Genetics Jena in the actual year


2004
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
162
 		T Liehr.
14. Fetal Cell Workshop.
Down’s Screening News 2004, 11:42. 		n.a.
 		PRE
161
 		T Liehr.
14. Workshop on fetal Cells and fetal DNA.
ECA-newsletter 2004, 14:16. 		n.a. PRE
160
 		 T Liehr.
Pränataldiagnostik – Zwischen Gen-check und Ultraschall – Tagungsbericht.
Uni-Journal Jena 2004, 07/04:28.		 n.a. PRE
159
 		T Liehr.
14 Workshop on Fetal Cells and Fetal DNA – Tagungsbericht;
Med Genetik 2004, 16:132. 		n.a. PRE
158
 		T Liehr, A Heller, KH Eichhorn, V Beensen, E Schulze, H Starke, U Claussen, I Schreyer.
Inherited cryptic chromosomal aberrations may be more easily detected in their balanced forms: a case report with hidden der(1)t(1;17)(q44;p13.2).
Prenat Diagn 2004, 24:1022-1024.  		1.612 CG
157
 		E Gebhart, J Ries, J Wiltfang, T Liehr, T Efferth.
Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas.
Arch Med Res 2004, 35:385-394.  		1.286 TCG
156
 		A Polityko, O Maltseva, N Rumyantseva, O Khurs, J Seidel, U Claussen, A Weise, T Liehr, H Starke.
Two further AHO-like syndrome patients with deletion of glypican 1 gene region in 2q37.2-q37.3.
Int J Mol Med 2004, 14:977-979.  		3.190 CG
155
 		C Rudolph, D Steinemann, N Von Neuhoff, D Gadzicki, T Ripperger, HG Drexler, K Mrasek, T Liehr, U Claussen, M Emura, E Schröck, B Schlegelberger.
Molecular cytogenetic characterization of the mantle cell lymphoma cell line GRANTA-519.
Cancer Genet Cytogenet 2004, 153:144-150.  		1.577 TCG
154
 		W Zumkeller, M Volleth, P Muschke, H Tönnies, A Heller, T Liehr, P Wieacker, M Stumm.
Genotype/phenotype analysis in a patient with pure and complete trisomy 12p.
Am J Med Genet A 2004, 129A:261-264.  		0.815 CG
153
 		T Liehr, U Claussen, H Starke.
Small supernumerary marker chromosomes (sSMC) in humans.
Cytogenet Genome Res 2004, 107:55-67.   		1.341 sSMC
152
 		H Lehrer, A Weise, S Michel, H Starke, K Mrasek, A Heller, A Kuechler, U Claussen, T Liehr.
The hierarchically organized splitting of chromosomal bands into sub-bands analyzed by multicolor banding (MCB).
Cytogenet Genome Res 2004, 105:25-28.  		1.341 INT
151
 		M Codina-Pascual, M Oliver-Bonet, J Navarro, H Starke, T Liehr, C Gutierrez-Mateo, JF Sanchez-Garcia, O Arango, J Egozcue, J Benet.
FISH characterization of a dicentric Yq (p11.32) isochromosome in an azoospermic male.
Am J Med Genet A 2004, 127:302-306.  		0.815 CG
150
 		J Camps, K Mrasek, E Prat, A Weise, H Starke, J Egozcue, R Miró, T Liehr.
Molecular cytogenetic characterisation of the colorectal cancer cell line SW480.
Oncol Rep 2004, 11:1215-1218.  		1.356 TCG
149
 		U Keller, A Kuechler, T Liehr, E Müller, G Grabenbauer, R Sauer, L Distel.
Impact of various parameters in detecting chromosomal aberrations by FISH to describe radiosensitivity.
Strahlenther Onkol 2004, 180:289-296.  		3.121 TCG
148
 		T Liehr, K Mrasek, A Weise, A Kuechler, F von Eggeling, U Claussen, H Starke.
Characterization of small supernumerary marker chromosomes (sSMC) in human.
Current Genomics 2004, 5:279-286. 		n.a. sSMC
147
 		T Liehr, G Hickmann, P Kozlowski, U Claussen, H Starke.
Molecular-cytogenetic characterization of the origin and presence of pericentromeric euchromatin on minute supernumerary marker chromosomes (SMCs).
 Chromosome Res 2004, 12:239-244.  		2.346 sSMC
146
 		D Boehm, S Herold, A Kuechler, T Liehr, F Laccone.
Rapid detection of subtelomeric deletion/duplication by novel real-time quantitative PCR using SYBR-green dye.
Hum Mutat 2004, 23:368-378.  		6.845 CG
M
145
 		F Sun, M Oliver-Bonet, T Liehr, H Starke, E Ko, A Rademaker, J Navarro, J Benet, RH Martin.
Human male recombination maps for individual chromosomes.
Am J Hum Genet 2004, 74:521-531.  		12.340 CG
144
 		T Liehr, H Starke, A Weise, H Lehrer, U Claussen.
Multicolor FISH probe sets and their applications.
Histol Histopathol 2004, 19:229-237.  		1.931 M
143
 		A Heller, HJ Fricke, H Starke, IF Loncarevic, U Claussen, T Liehr.
Characterization of a highly aberrant plasma cell leukemia karyotype: A case report.
Oncol Rep. 2004, 11:89-92.  		1.356 TCG
142
 		A Heller, IF Loncarevic, M Glaser, E Gebhart, U Trautmann, U Claussen, T Liehr.
Breakpoint differentiation in chromosomal aberrations of hematological malignancies: Identification of 33 previously unrecorded breakpoints.
Int J Onc 2004, 24:127-136.  		3.056 TCG
66% of publications of Institute of Human Genetics Jena in the actual year
          

2003
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
141
 		U Grasshoff, S Singer, T Liehr, H Starke, B Fode, M Schoning, A Dufke.
A complex chromosomal rearrangement with a translocation 4;10;14 in a fertile male carrier: ascertainment through an offspring with partial trisomy 14q24-->1q22 and partial monosomy 4q27-->q28.
Cytogenet Genome Res 2003, 103:17-23.  		0.497 CG
140
 		T Liehr, A Nietzel, A Weise, K Mrasek, F von Eggeling, U Claussen, H Starke.
A strategy for the characterization of small supernumerary marker chromosomes (SMC).
Balk J Med Gen 2003, 6:69-72.  		n.a. sSMC
139
 		A Weise, A Heller, H Starke, K Mrasek, A Kuechler, BL Pool-Zobel, U Claussen, T Liehr.
Multitude multicolor chromosome banding (mMCB)- a comprehensive one-step multicolor FISH banding method.
Cytogenet Genome Res 2003, 103:34-39.  		0.497 M
138
 		A Weise, O Rittinger, H Starke, M Ziegler, U Claussen, T Liehr.
De novo 9-break-event in one chromosome 21 combined with a microdeletion in 21q22.11 in a mentally retarded boy with short stature.
Cytogenet Genome Res 2003, 103:14-16.   		0.497 CG
137
 		H Starke, A Nietzel, A Weise, A Heller, K Mrasek, B Belitz, C Kelbova, M Volleth, B Albrecht, B Mitulla, R Trappe, I Bartels, S Adolph, A Dufke, S Singer, M Stumm, R-D Wegner, J Seidel, A Schmidt, A Kuechler, I Schreyer, U Claussen, F von Eggeling, T Liehr.
Small supernumerary marker chromosomes (SMC): genotype-phenotype correlation and classification.
Hum Genet 2003, 114:51-67.   		4.022 sSMC
136
 		E Gebhart, T Liehr, E Wolff, J Wiltfang, S Koscielny, J Ries.
Loss of 9p21 is embedded in a complex but consistent pattern of genomic imbalances in oral squamous cell carcinomas.
Cytogenet Genome Res 2003, 101:106-112.  		0.497 TCG
135
 		I Bartels, G Schlueter, T Liehr, F von Eggeling, H Starke, R Glaubitz, P Burfeind.
Supernumerary small marker chromosome (SMC) and uniparental disomy 22 in a child with confined placental mosaicism of trisomy 22: Trisomy rescue due to marker chromosome formation.
Cytogenet Genome Res 2003, 101:103-105.  		0.497 CG
134
 		M Volleth, M Stumm, VM Kalscheuer, K Reschke, T Liehr, P Wieacker.
Prämature Ovarialinsuffizienz bei einer Patientin mit einem ungewöhnlichen pseudoisodizentrischen X-Chromosom.
Geburtshilfe Frauenheilkd 2003, 63:1054-1057.  		n.a. CG
133
 		M Oliver-Bonet, T Liehr, A Nietzel, A Heller, H Starke, U Claussen, M Codina-Pascual, A Pujol, C Abad, J Egozcue, J Navarro, J Benet.
Karyotyping of human synaptonemal complexes by cenM-FISH.
Europ J Hum Genet 2003, 11:879-883.  		3.669 INT
132
 		A Heller, V Trifonov, N Rubtsov, A Sauerbrey, H Starke, IF Loncarevic, U Claussen, T Liehr.
Complex chromosomal rearrangements in a secondary acute myeloblastic leukemia after chemotherapy in TRAPS.
Oncol Rep 2003, 10: 1789-1792.  		1.256 TCG
131
 		H Starke, B Mitulla, V Beensen, V Trifonov, N Rubtsov, A Heller, M Ziegler, A Neumann, U Claussen, T Liehr.
First postnatal case of mosaic del(22)/r(22).
Prenat Diagn 2003, 23:765-767.  		1.475 CG
130
 		A Heller, L Brecevic, M Glaser, I Loncarevic, E Gebhart, U Claussen, T Liehr.
Trisomy 8 as the sole chromosomal aberration in myelocytic malignacies: a comprehensive molecular cytogenetic analysis reveals no cryptic aberrations.
Cancer Genet Cytogenet 2003, 146:81-83.  		1.542 TCG
129
 		F von Eggeling, S Langer, C Hoppe, T Liehr, A Weise, G Lederer, D Kotzot.
Presumed mutation in a microsatellite marker mimicking segmental uniparental disomy in a case of a small supernumerary marker chromosome detected at prenatal diagnosis.
Clin Genet 2003, 64:168-171    		2.025 sSMC
UPD
128
 		S Sauter, G von Beust, P Burfeind, A Weise, H Starke, T Liehr, B Zoll.
Autistic disorder and chromosomal mosaicism 46,XY[123]/46,XY,del(20)(pter->p12.2)[10].
Am J Med Genet 2003, 120A:533-536.   		2.603 CG
127
 		RW Kinne, W Kunisch, V Beensen, T Zimmermann, F Emmrich, P Petrow, W Lungershausen, G Hein, RK Braun, M Foerster, C Kroegel, R Winter, E Liesaus, RA Fuhrmann, A Roth, U Claussen, T Liehr.
Synovial fibroblasts and synovial macrophages from patients with rheumatoid arthritis and other inflammatory joint diseases show chromosomal aberrations.
Genes Chromosomes Cancer 2003, 38:53-67. 		4.192 CG
126
 		T Liehr, M Ziegler, H Starke, A Heller, A Kuechler, G Kittner, V Beensen, J Seidel, H Häßler, J Müsebeck, U Claussen.
Conspicuous GTG banding results of the centromere near region can be caused by alphoid DNA heteromorphism.
Clin Genet 2003, 64:166-167.  		2.025 HET
125
 		K Mrasek, A Heller, N Rubtsov, V Trifonov, H Starke, U Claussen, T Liehr.
Detailed Hylobates lar karyotype defined by 25-color FISH and multicolor banding.
Int J Mol Med 2003, 12:139-146.  		1.940 EVO
124
 		J Seidel J, A Heller, G Senger, H Starke, I Chudoba, C Kelbova, H Tonnies, H Neitzel, C Haase, V Beensen, F Zintl, U Claussen, T Liehr.
A multiple translocation event in a patient with hexadactyly, facial dysmorphism, mental retardation and behaviour disorder characterized comprehensively by molecular cytogenetics. Case report and review of the literature.
Eur J Pediatr 2003, 162:582-588. 		1.157 CG
123
 		A Kuechler, M Dreidax, SU Piegorsch, T Liehr, U Claussen, TG Wendt, J Dunst.
Residual chromosomal damage after radiochemotherapy with and without amifostine detected by 24-color FISH.
Strahlenther Onkol 2003, 179:493-498.    		2.634 TCG
122
 		A Heller, N Rubtsov, S Kytölä, TV Karamysheva, OV Sablina, MM Degtyareva, H Starke, H Metzke, U Claussen, T Liehr.
Highly complex karyotypic changes in acute myelogenous leukemia: a case report.
Int J Onc 2003, 23:139-143.  		2.536 TCG
121
 		V Trifonov, J Seidel, H Starke, M Prechtel, V Beensen, M Ziegler, I Hartmann, A Heller, A Nietzel, U Claussen, T Liehr.
Enlarged chromosome 13 p-arm hiding a cryptic partial trisomy 6p22.2-pter.
Prenat Diagn 2003, 23:427-430.  		1.475 CG
120
 		A Schaeferhenrich, G Beyer-Sehlmeyer, G Festag, A Kuechler, N Haag, A Weise, T Liehr, U Claussen, Marian, W Sendt, J Scheele, BL Pool-Zobel.
Human adenoma cells are highly susceptible to the genotoxic action of 4-hydroxy-2-nonenal.
Mutat Res 2003, 526:19-32.  		1.748 TCG
119
 		T Liehr, H Starke, A Heller, A Weise, V Beensen, G Senger, G Kittner, M Prechtel, U Claussen, J Seidel.
Evidence for a new microdeletion syndrome in 15q21.
Int J Mol Med, 11:575-578.   		1.940 CG
118
 		G Houge, T Liehr, J Schoumans, GO Ness, K Solland, H Starke, U Claussen, P Strømme, B Åkre, S Vermeulen.
Ten years follow up of a boy with a complex chromosomal rearrangement: Going from a > 5 to 15-breakpoint CCR.
Am J Med Genet 2003, 118A:235-240. 		2.603 CG
117
 		A Schaeferhenrich, W Sendt, J Scheele, A Kuechler, T Liehr, U Claussen, A Rapp, KO Greulich, BL Pool-Zobel.
Putative colon cancer risk factors damage global DNA and TP53 in primary human colon cells isolated from surgical samples.
Food Chem Toxicol 2003, 41:655-664.  		1.898 TCG
116
 		A Weise, P Harbarth, U Claussen, T Liehr.
Fluorescence in situ hybridization (FISH) on human chromosomes using PHOTOPROBE(R) biotin labeled probes.
J Histochem Cytochem 2003, 51:549-551.  		2.408 M
115
 		A Nietzel, B Albrecht, H Starke, A Heller, G Gillessen-Kaesbach, U Claussen, T Liehr.
Partial hexasomy 15pter->15q13 including SNRPN and D15S10: first molecular cytogenetically proven case report.
J Med Genet 2003, 40:E28,1-4 . 		6.368 CG
114
 		T Liehr, A Nietzel, H Starke, A Heller, A Weise, A Kuechler, G Senger, S Ebner, T Martin, M Stumm, R Wegner, H Tönnies, C Hoppe, U Claussen, F von Eggeling.
Characterization of small marker chromosomes (SMC) by recently developed molecular cytogenetic approaches.
J Ass Genet Techn 2003, 29:5-10.  		n.a. sSMC
113
 		A Kuechler, A Weise, S Michel, A Schaeferhenrich, BL Pool-Zobel, U Claussen, T Liehr.
Precise breakpoint characterization of the colon adenocarcinoma cell line HT-29 clone 19A by means of 24-color fluorescence in situ hybridization and multicolor banding.
Genes Chromosomes Cancer 2003, 36:207-210.  		4.192 TCG
112
 		H Starke, B Mitulla, A Nietzel, A Heller, V Beensen, G Grosswendt, U Claussen, F von Eggeling, T Liehr.
First case of trisomy 21 accompanied by an additional der(4)(:p11->q11:) plus partial uniparental disomy 4p15-16.
Am J Med Genet 2003, 116A:26-30. 		2.603 sSMC
62% of publications of Institute of Human Genetics Jena in the actual year


2002
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
111
 		U Claussen, S Michel, P Mühlig, M Westermann, UW Grummt, K Kromeyer-Hauschild, T Liehr.
Demystifying chromosome preparation and the implications for the concept of chromosome condensation during mitosis.
Cytogenet Genome Res 2002, 98:136-146.  		1.114 CG
M
110
 		A Weise, T Liehr, T Efferth, A Kuechler, E Gebhart.
Comparative M-FISH and CGH analyses in sensitive and drug-resistant human T-cell acute leukemia cell lines.
Cytogenet Genome Res 2002, 98:118-125.  		1.114 TCG
109
 		R Trappe, D Böhm, J Kohlhase, A Weise, T Liehr, G Essers, M Meins, B Zoll, I Bartels, P Burfeind.
A novel family-specific translocation t(2;20)(p24.1;q13.1) associated with recurrent abortions: molecular characterization and segregation analysis in male meiosis.
Cytogenet Genome Res 2002, 98:1-8. 		1.114 CG
108
 		U Steinhaeuser, H Starke, A Nietzel, J Lindenau, P Ullmann, U Claussen, T Liehr.
Suspension S-FISH  a new technique for interphase.
J Histochem Cytochem, 2002 50:1697-1698.  		2.283 M
INT
107
 		H Starke, J Seidel, W Henn, S Reichardt, M Volleth, M Stumm, C Behrend, KR Sandig, C Kelbova, G Senger, B Albrecht, I Hansmann, A Heller, U Claussen, T Liehr.
Homologous sequences at human chromosome 9 bands p12 and q13-21.1 are involved in different patterns of pericentric rearrangements.
Eur J Hum Genet 2002, 10:790-800.  		3.136 HET
106
 		J Lemke, J Claussen, S Michel, I Chudoba, P Mühlig, M Westermann, K Sperling, N Rubtsov, UW Grummt, P Ullmann, K Kromeyer-Hauschild, T Liehr, U Claussen.
The DNA-based structure of human chromosome 5 in interphase.
Am J Hum Genet 2002, 71:1051-1059.  		10.649 INT
105
 		T Liehr, A Weise, A Heller, H Starke, K Mrasek, A Kuechler, H-UG Weier, U Claussen.
Multicolor chromosome banding (MCB) with YAC/BAC-based probes and region-specific microdissection DNA libraries.
Cytogenet Genome Res 2002, 97:43-47 . 		1.114 M
104
 		T Liehr, A Nietzel, H Starke, A Heller, A Weise, K Mrasek, U Claussen.
Characterization of small human marker chromosomes by centromere-specific multicolor-FISH (cenM-FISH) and high resolution multicolor banding (MCB).
ECA-newsletter 2002, 10:3-8. 		n.a. sSMC
103
 		F v Eggeling, C Hoppe, U Bartz, H Starke, G Houge, U Claussen, G Ernst, D Kotzot, T Liehr.
Maternal uniparental disomy 12 in a healthy girl with a 47,XX,+der(12)(:p11->q11:)/46,XX karyotype.
J Med Gen 2002, 39:519-521.  		7.774 sSMC
UPD
102
 		T Liehr, I Schreyer, A Neumann, V Beensen, M Ziegler, I Hartmann, H Starke, A Heller, A Nietzel, Claussen.
Two more possible pitfalls of rapid prenatal diagnosis using interphase nuclei.
Prenat Diagn 2002, 22:497-499.  		1.802 CG
PRE
101
 		A Weise, H Starke, A Heller, H Tönnies, M Volleth, M Stumm, G Senger, A Nietzel, U Claussen, T Liehr.
Chromosome 2 aberrations in clinical cases characterized by high resolution multicolor banding (MCB) and region specific FISH probes.
J Med Genet 2002, 39:434-439.
 7.774 CG
100
 		T Liehr, U Claussen.
Current developments in human molecular cytogenetic techniques.
Curr Mol Med 2002, 2:283-297.  		n.a. M
99
 		T Liehr, U Claussen.
Multicolor-FISH approaches for the characterization of human chromosomes in clinical genetics and tumor cytogenetics.
Current Genomics 2002, 3:213-235.  		n.a. CG
TCG
98
 		T Liehr, A Heller, H Starke, U Claussen.
FISH banding methods: applications in research and diagnostics.
Expert Review Mol Diagn 2002, 2:217-225.
 		n.a. M
97
 		A Heller, H Starke, V Trifonov, N Rubtsov, U Wedding, I Loncarevic, C Bleck, U Claussen, T Liehr.
A complex translocation event between the two homologues of chromosomes 5 leading to a del(5)(q21q33) as a sole aberration in a case clinically diagnosed as CML – characterization of the aberration by multicolor banding (MCB).
Int J Onc 2002, 20:1179-1181.  		2.931 TCG
96
 		IF Loncarevic, J Römer, H Starke, A Heller, C Bleck, M Ziegler, W Fiedler, T Liehr, JH Clement, U Claussen.
 Heterogenic molecular basis for loss of ABL1-BCR transcription: Deletions in der(9)t(9;22) and variants of standard t(9;22) in BCR-ABL1-positive chronic myeloid leukemia.
Genes Chr Cancer 2002, 34:193-200.  		4.199 TCG
95
 		A Kuechler, S Neubauer, GG Grabenbauer, U Claussen, T Liehr, R Sauer, TG Wendt.
Is 24-color-FISH-detection of in vitro radiation-induced chromosomal aberrations suited to determine individual intrinsic radiosensitivity?
Radiother Oncol 2002, 178:209-215.  		2.838 TCG
94
 		T Liehr, M Schmidt, H Starke, M Ziegler, G Kittner, A Heller, N Rubtsov, V Trifonov, U Claussen.
First case of trisomy 13 plus mosaic trisomy 1q.
Fetal Diag Ther 2002, 17:133-136.   		1.053 CG
93
 		T Liehr, A Heller, H Starke, N Rubtsov, V Trifonov, K Mrasek, A Weise, A Kuechler, U Claussen.
Microdissection based high resolution multicolor banding (MCB) for all 24 human chromosomes.
Int J Mol Med 2002, 9:335-339.  		2.063 M
92
 		A Weise, H Starke, A Heller, U Claussen, T Liehr.
Evidence for interphase DNA decondensation transverse to the chromosome axis – a multicolor banding (MCB) analysis.
Int J Mol Med 2002, 9:359-361.  		2.063 INT
91
 		T Liehr, A Heller, H Starke, U Claussen.
High quality CGH slides irrespective of used lymphocyte suspension.
Technical Tips Online Internet: (http://www.elsevier.com/locate/tto) TTO 2002, 1:138, T02436 
no longer available.
 		13.216 M
61% of publications of Institute of Human Genetics Jena in the actual year


2001
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor
 		Topic
90
 		A Kuechler, CR Mueller, T Liehr, U Claussen.
Detection of microdeletions in the short arm of the X chromosome by chromosome stretching.
Cytogenet Cell Genet. 2001, 95:12-16.   		1.271 CG
89
 		H Starke, G Senger, M Kossakiewicz, H Tittelbach, D Rau, N Rubtsov, V Trifonov, A Heller, I Hartmann, U Claussen, T Liehr.
Maternal insertion of 18q11.2-q12.2 in 18p11.3 of the same chromosome analysed by microdissection and multicolour banding (MCB).
Prenat Diag 2001, 21:1049-1052.  		1.792 CG
88
 		S Scheil, S Brüderlein, T Liehr, H Starke, J Herms, M Schulte, P Möller.
Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1.
Genes Chr Cancer 2001, 32:203-211.   		4.416 TCG
87
 		K Mrasek, A Heller, N Rubtsov, V Trifonov, H Starke, M Rocchi, U Claussen, T Liehr.
Reconstruction of the female Gorilla gorilla karyotype by Zoo-FISH using 25-color FISH and multicolor banding (MCB).
Cytogenet Cell Genet 2001, 93:242-248.   		1.271 EVO
86
 		RW Kinne, T Liehr, V Beensen, E Kunisch, T Zimmermann, H Holland, R Pfeiffer, H-D Stahl, W Lungershausen, G Hein, A Roth, F Emmrich, U Claussen, UG Froster.
Mosaic chromosomal aberrations in synovial fibroblasts of patients with rheumatoid arthritis, osteoarthritis, and other inflammatory joint diseases.
Arthritis Res, 2001, 3:319-330.  		3.436 CG
85
 		A Dufke, C Walczak, T Liehr, H Starke, V Trifonov, N Rubtsov, M Schöning, H Enders, T Eggermann.
Partial tetrasomy 12pter-12p12.3 in a girl with Pallister-Killian syndrome: extraordinary finding of an analphoid, inverted duplicated marker.
Europ J Hum Genet 2001, 9:572-576.   		3.173 sSMC
84
 		T Liehr, V Beensen, H Starke, R Hauschild, E Hempel, V Fritsche, C Hoppe, G Großwendt, M Prechtel, M Ziegler, U Claussen, F von Eggeling.
Tetrasomy 21 due to a de novo Robertsonian translocation t(14;21) and an additional free trisomy 21.
Clin Genet 2001, 60:83-86.   		2.395 CG
83
 		H Starke, M Raida, V Trifonov , J H Clement, IF Loncarevic, A Heller, C Bleck, A Nietzel, N Rubtsov, U Claussen, T Liehr.
Molecular cytogenetic characterization of an acquired supernumerary minute marker chromosome as sole abnormality in a case clinically diagnosed as Philadelphia negative chronic myelogenous leukaemia.
Br J Haematol 2001, 113:435-438.   		2.815 TCG
82
 		T Liehr, V Beensen, R Hauschild, M Ziegler, I Hartmann, H Starke, A Heller, C Kähler, M Schmidt, W Reiber, M Hesse, U Claussen.
Pitfalls of rapid prenatal diagnosis using the interphase nucleus.
Prenat Diagn 2001, 21:419-421.  		1.792 PRE
CG
81
 		A Bleichert, W Fiedler, U Claussen, G Ernst, IF Loncarevic, A Heller, T Liehr, C Kunert, F von Eggeling.
A long distance-PCR derived FISH probe detects a deletion between p15 and p16 in CML and T-ALL patients.
Int J Mol Med 2001, 7:591-595.   		1.689 TCG
80
 		A Rump, G Kasper, C Hayes, G Wen, H Starke, T Liehr, R Lehmann, D Lagemann, A Rosenthal.
Complex arrangement of genes within a 220-kb region of double-duplicated DNA on human 2q37.1.
Genomics 2001, 73:50-55.  		3.418 CG
79
 		YX Yu, A Heller, T Liehr, L Aurelian.
Expression analysis and chromosome location of a novel gene (H11) associated with the growth of human melanoma cells.
Int J Onc 2001, 18:905-911.   		2.330 TCG
78
 		G Alves, A Heller, W Fiedler, M Mendes Campos, U Claussen, AA Ornellas, T Liehr.
Genetic imbalances in 26 penile SCC cases.
Genes Chr Cancer 2001, 31:48-53.  		4.416 TCG
77
 		T Liehr, LT Reiter, JR Lupski, T Murakami, U Claussen, B Rautenstrauss.
Regional localization of 10 mariner transposon like ESTs by means of FISH – evidence for a correlation with fragile sites.
Mamm Genome 2001, 12:326-328. 		2.318 INT
76
 		A Nietzel, M Rocchi, A Heller, H Starke, I Wlodarska, V Beensen, U Claussen, T Liehr.
A new multicolor-FISH approach for the characterization of marker chromosomes: Centromere-specific multicolor-FISH (cenM-FISH).
Hum Genet 2001, 108:199-204.  		3.209 sSMC
M
75
 		S Stein, T Liehr, K Eschrich.
Characterization of the mouse liver fructose-1,6-bisphosphatase gene.
Gene 2001, 264:215-224.  		3.041 CG
74
 		V Bureau, S Marionneau, A Cailleau-Thomas, B Le Moullac-Vaidye, T Liehr, J Le Pendu.
 Comparison of the three rat GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferases FTA, FTB and FTC.
Eur J Biochem 2001, 268:1006-1019.   		2.849 CG
33% of publications of Institute of Human Genetics Jena in the actual year


 2000
Number
 Authors/ Title/ Where Contribution was Published
 Impact Factor Topic
73
 A Dufke, J Seidel, M Schöning, M Döbler-Neumann, C Kelbova, T Liehr, V Beensen, C Backsch, U Klein-Vogler, H Enders.
Microdeletion 4p16.3 in three unrelated patients with Wolf-Hirschhorn-syndrome.
Cytogenet Cell Genet 2000, 91:81-84.  		1.409 CG
72
 NB Rubtsov, TV Karamisheva, NM Astakhova, T Liehr, U Claussen, NS Zhdanova.
Zoo-FISH with region-specific paints for the mink chromosome 5q: delineation of inter- and intrachromosomal rearrangements in human, pig, fox, and Iberian shrew.
Cytogenet Cell Genet 2000, 90:268-270.  		1.409 EVO
71
 C Kebelmann-Betzing, K Seeger, A Kulozik, G Henze, T Liehr, A Heller, A Teigler-Schlegel.
Secondary acute myeloid leukemia after treatment of acute monoblastic leukemia.
N Engl J Med 2000, 343:1897-1898.   		29.512 TCG
70
 S Jakubiczka, B Mitulla, T Liehr, J Arnemann, H Lehrach, R Sudbrak, M Stumm, PF Wieacker, T Bettecken.
Incidental prenatal detection of an Xp deletion using an anonymous primer pair for fetal sexing.
Prenat Diagn 2000, 20:842-846.  		1.647 CG
69
 C Helmken, A Wetter, S Rudnik-Schöneborn, T Liehr, K Zerres, B Wirth.
An essential SMN interacting protein (SIP1) is not involved in the phenotypic variability of spinal muscular atrophy (SMA).
Europ J Hum Genet 2000, 8:493-499.  		3.175 CG
68
 A Heller, J Seidel, A Hübler, H Starke, V Beensen, G Senger, M Rocchi, J Wirth, I Chudoba, U Claussen, T Liehr.
Molecular cytogenetic characterisation of partial trisomy 9q in a case with pyloric stenosis and a review.
J Med Genet 2000, 37:529-532.  		3.290 CG
67
    H Tillmann, S Stein, T Liehr, K Eschrich.
Structure and chromosomal localization of the human and mouse muscle fructose-1,6-bisphosphatase genes.
Gene 2000, 247:241-253.  		2.461 CG
66
 A Hübler, J Seidel, E Kauf, D Schramm, V Beensen, A Heller, T Liehr, F Zintl.
Insulin-like growth factor serum concentrations reflect insufficient growth in a hypoplastic infant with partial trisomy 9q in the 12th week of life.
J Pediatr Endocrinol Metab 2000, 13:445-450.  		0.638 CG
65
 K Bayerlein, T Rith, I Verdörfer, T Liehr, E Wolff, S Girod, E Gebhart.
I-FISH control of CGH-detected gain of DNA sequence copy number in oral squamous cell carcinomas.
Anticancer Res 2000, 20:427-432.    		1.331 TCG
64
 K König, A Göhlert, T Liehr, I F Loncarevic, I Riemann.
Two-Photon Multicolor FISH: a versatile technique to detect specific sequences with in single DNA molecules in cells and tissues.
Single Molecules 2000, Vol 1:41-51.   		n.a. M
63
 A Heller, I Chudoba, C Bleck, G Senger, U Claussen, T Liehr.
Microdissection based comparative genomic hybridization (micro-CGH) analysis of secondary acute myelogenous leukemias.
Int J Onc 2000, 16:461-468. 		2.142 TCG
62
 E Gebhart, T Liehr.
Patterns of genomic imbalances in human solid tumors (Review).
Int J Onc 2000, 16:383-399.  		2.142 TCG
44% of publications of Institute of Human Genetics Jena in the actual year


 1999
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
61
 		H Starke, I Schreyer, C Kähler, W Fiedler, V Beensen, A Heller, A Nietzel, U Claussen, T Liehr.
Molecular cytogenetic characterization of a prenatally detected supernumerary minute marker chromosome 8.
Prenatal Diagn 1999, 19:1169-1174.  		1.885 sSMC
60
 		D Carbonnelle, T Liehrr, C Jacquot, D Masson, P Lustenberger, MG Denis, C Roussakis.
Assignment of the serologically defined colon cancer antigen 1 gene (SDCCAG1) to human chromosome band 14q22 by in situ hybridization.
Cytogenet Cell Genet 1999, 86:248-249.  		1.604 CG
59
 		K Hühne, O Park, T Liehr, B Rautenstrauss.
Expression analysis of the PMP22 gene in glioma and osteogenic sarcome cell lines.
J Neurosci Res 1999, 58:624-631. 		3.126 TCG
58
 		LT Reiter, T Liehr, B Rautenstrauss, HM Robertson, JR Lupski.
Localization of mariner DNA Transposons in the Human Genome by PRINS.
Genome Res 1999, 9:839-843.  		7.062 CG
57
 		E Gebhart, T Liehr.
Clonality determined by fluorescence in situ hybridization of single-cell aberrations in hematopoietic neoplasias.
Cancer Genet Cytogenet 1999, 113:193-194.  		1.756 TCG
56
 		F von Deimling, JM Scharf, T Liehr, M Rothe, AR Kelter, P Albers, WF Dietrich, LM Kunkel, N Wernert, B Wirth.
Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma.
Hum Genet 1999, 105:17-27.  		3.145 TCG
55
 		T Liehr, G Kuhlenbäumer, P Wulf, V Taylor, U Suter, C Van Broeckhoven, J R Lupski, U Claussen, B Rautenstrauss.
Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3.
Genomics, 1999, 58:106-108. 		3.386 CG
54
 		T Liehr, U Claussen, E Gebhart.
Nucleus extraction from single mounted tissue section.
Genetic Analysis (Biomolecular Engeneering), 1999, 15:65-69.  		0.778 M
53
 		M Döbler, J Schuh, F Kiesewetter, H Schell, T Liehr, E Gebhart.
Deletion monitoring in skin tumors by interphase-FISH using band-specific DNA probes.
Int J Oncol 1999, 14:571-576.  		1.381 TCG
52
 		T Liehr, H Starke, V Beensen, C Kähler, M Harbich, E Bude, M Ziegler, U Claussen.
Translocation trisomy dup(21q) and free trisomy 21 can be distinguished by interphase-FISH.
Int J Mol Med 1999, 3:11-14.  		1.058 CG
8% of publications of Institute of Human Genetics Jena in the actual year
coauthor or author in 25% of publications of Institute of Human Genetics Erlangen in the actual year


 1998
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
51
 		C Fuchs, T Liehr, S Özbey, A Ekici, B Rautenstrauss.
Charcot-Marie-Tooth disease type 1A and hereditary neuropathy with liability to pressure palsies: a SacI polymorphism in the proximal CMT1A-REP elements may lead to genetic misdiagnosis.
Neurogenetics 1998, 2:43-46.  		2.094 CG
50
 		S Neubauer, T Liehr, S Birkenhake, E Gebhart, R Fietkau, R Sauer.
Estimation of DNA single strand breaks by single cell gel electrophoresis in tumor cells.
Genetic Analysis (Biomolecular Engineering) 1998, 14:121-124.  		0.778 TCG
M
49
 		A Taubald, T Liehr, E Haßfurther, J Ries, S Girod, E Gebhart.
CGH-detected DNA sequence copy number amplifications can be confirmed by interphase-FISH: new possiblities for prognostic approaches in oral squamous cell carcinomas.
Int J Mol Med 1998, 2:555-560.  		1.058 TCG
48
 		T Liehr, M Kirsch, U Trautmann, E Gebhart.
Fluorescence in situ hybridization on G-banded chromosome preparations mounted with Eukitt in a retrospective study and in routine diagnostics.
Cancer Genet Cytogenet 1998, 107:85-86.  		1.756 TCG
47
 		C Lange, T Liehr, M Goen, E Gebhart, B Fleckenstein, A Ensser.
New eukaryotic semaphorins with close homology to semaphorins of DNA-viruses.
Genomics 1998, 51:340-350. 		3.386 CG
46
 		T Liehr, J Ries, E Wolff, W Fiedler, R Dahse, G Ernst, H Steininger, S Koscielny, S Girod, E Gebhart.
Gain of DNA copy number on chromosomes 3q26-qter and 5p14-pter is a frequent finding in head and neck squamous cell carcinomas.
Int J Mol Med 1998, 2:173-179.  		1.058 TCG
45
 		E Wolff, S Girod, T Liehr, U Vorderwülbecke, J Ries, H Steininger, E Gebhart.
Oral squamous cell carcinomas are characterized by a rather uniform pattern of genomic imbalances detected by comparative genomic hybridization.
Europ J Cancer 1998, 34:186-190.  		2.537 TCG
44
 		T Liehr, RA Pfeiffer, U Trautmann, E Gebhart.
Centromeric alphoid DNA heteromorphisms of chromosome 22 revealed by FISH-technique.
Clin Genet 1998, 53:231-232.  		1.391 HET
43
 		E Gebhart, T Liehr, E Wolff, J Ries, W Fiedler, H Steininger, S Koscielny, S Girod.
Pattern of genomic imbalances in oral squamous cell carcinomas with and without an increased copy number of 11q13.
Int J Onc 1998, 12:1151-1155.  		1.381 TCG
42
 		B Rautenstrauss, C Fuchs, A Ekici, E Nelis, C Van Broeckhoven, T Liehr.
Assay of transfection rate in insect cells on a single cell level.
Genetic Analysis (Biomolecular Engineering) 1998, 14:103-104.  		0.778 M
41
 		B Rautenstrauss, U Zechner, H Hameister, H Grehl, T Liehr.
Expression pattern of the peripheral myelin protein 22kDa (PMP22) in neural and non-neural tissue types of adult wildtype and trembler mice - a comparative study.
J Periph Nerv Syst 1998, 3:117-124.  		n.a. CG
40
 		B Rautenstrauss, T Liehr, C Fuchs, A Bevot, A Bornemann, E Postler, R Meyermann, S Uhlhaas, W Friedl, R Michaelis.
Mosaicism for Charcot-Marie-Tooth disease type 1A: Onset in childhood suggests somatic reversion in early developmental stages.
Int J Mol Med 1998, 1:333-337.  		1.058 CG
39
 		KG Michels-Rautenstrauss, CY Mardin, W M Budde, T Liehr, J Polansky, T Nguyen, V Timmerman, C Van Broeckhoven, GOH Naumann, RA Pfeiffer, BW Rautenstrauss.
Juvenile open angle glaucoma: fine mapping of the TIGR gene to 1q24.3-25.2 and mutation analysis.
Hum Genet 1998, 102:103-106.   		3.145 CG
38
 		F Pröls, T Liehr, B Loser, B Rautenstrauss.
Regional localization of rat Flic1, a calcyclin/S100A6-like gene to rat chromosome 7q22-31 by means of FISH.
Mamm Genome 1998, 9:94-95. 
1.890 CG
18% of publications of Institute of Human Genetics Jena in the actual year
coauthor or author in ~40% of publications of Institute of Human Genetics Erlangen in the actual year


 1997
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
37
 		F Pröls, T Liehr, R Rinka, B Rautenstrauss.
Assignement of microvascular endothelial differentiation gene 1 (MDG1) to human chromosome band 14q24.2->q24.3 by fluorescence in situ hybridization.
Cytogenet. Cell Genet 1997, 79:149-150.
 		1.604 CG
36
 		T Liehr.
Two-color or one-color FISH? - Comment to: A rapid method for the diagnosis of Charcot Marie Tooth disease type 1A by FISH.
Trends in Genetics 1997, 13:p??
16.342 CG
M
35
 		T Liehr, H Grehl, B Rautenstrauss.
Accumulation of periperal myelin protein 22 (PMP22) in onion bulbs of nerves biopsied from patients with different subtypes of Charcot-Marie-Tooth (CMT) disease type 1.
Acta Neuropathol 1997, 94:514-516.
 		2.402 CG
34
 		B Rautenstrauss, C Fuchs, T Liehr, H Grehl, T Murakami, J R Lupski.
Visualization of the CMT1A duplication and HNPP deletion by FISH on streched chromosome fibers.
J Periph Nervous Syst 1997, 2:319-322.
n.a. CG
33
 		B Rautenstrauss, T Liehr, UMH Schrell, H Grehl.
Use of FISH analyzis for prostate tumors and other tissue types.
Am J Pathol 1997, 151:1171-1172.
 		6.436 TCG
32
 		B Rautenstrauss, T Liehr, K D Bathke, H Lauffer, A Ekici A, C Fuchs, E Nelis, C Van Broeckhoven, H Grehl.
Fortschritte in der molekulargenetischen Diagnostik der Charcot-Marie-Tooth’schen Erkrankung (CMT) sowie der tomakulösen Neuropathie (engl.: hereditary neuropathy with liability to pressure palsies, HNPP).
Med Genetik 1997, 9:501-504.
n.a. CG
31
 		T Liehr, H Grehl, B Rautenstrauss.
Molecular diagnosis of PMP22-associated neuropathies using fluorescence in situ hybridization (FISH) on archival peripheral nerve tissue preparations.
Acta Neuropathol 1997, 94:266-271.
 		2.402 CG
30
 		E Wolff, T Liehr, U Vorderwülbecke, A H Tulusan, E M Husslein, E Gebhart.
Frequent gains and losses of specific chromosome segments in human ovarian carcinomas shown by comparative genomic hybridization.
Int J Onc 1997, 11:19-23.
1.381 TCG
29
 		C Fuchs, T Liehr, B Rautenstrauss.
High-resolution FISH of streched chromosome fibers.
Trends in Genetics 1997, 13:287.
 		16.342 CG
M
28
 		T Liehr, O Park, B G Feuerstein, E Gebhart, B Rautenstrauss.
The peripheral myelin protein 22kDa (PMP22) gene is amplified in cell lines derived from glioma and osteogenic sarcoma: a new candidate for an oncogene?
Int J Onc 1997, 10:915-919.
1.381 TCG
27
 		T Liehr, F Hallouin, B Rautenstrauss, J LePendu, M G Denis.
Mapping of two different alpha-1,2-fucosyltransferase genes to rat chromosome 1q22-31.
Mamm Genome 1997, 8:297-298.
1.890 CG
26
 		C Chadéneau, T Liehr, B Rautenstrauss, M G Denis.
The Tage4 gene maps to rat chromosome 1q22.
Mamm Genome 1997, 8:157-158.
1.890 CG
25
 		H Grehl, B Rautenstrauss, T Liehr, A Ekici, A Bickel, K Bathke, B Neundörfer.
Clinical and morphological phenotype of HMSN 1A mosaicism.
Neuromusc Disord 1997, 7:27-31.
 		2.749 CG
24
 		J Draeger, H Schell, F Kiesewetter, T Liehr, E Gebhart.
Chromosome gain and loss in paraffin sections from malignant melanomas of the skin.
Int J Onc 1997, 10:89-92.
1.381 TCG
23
 		A Dimmler, F Kiesewetter, T Liehr, S Neubauer, H Schell, E Gebhart.
Interphase-FISH examinations in paraffin sections from benign, precancerous, and cancerous lesions of the skin and oral mucosa.
Int J Onc 1997, 10:83-88.
1.381 TCG
22
 		V Timmerman, B Rautenstrauss, L T Reiter, T Koeuth, A Löfgren, T Liehr, E Nelis, K D Bathke, P De Jonghe, H Grehl, J-J Martin, J R Lupski, C Van Broeckhoven.
Detection of the CMT1A/HNPP recombination hotspot in unrelated patients of European descent.
J Med Genet 1997, 34:43-49.
2.986 CG
coauthor or author in ~40% of publications of Institute of Human Genetics Erlangen in the actual year


 1996
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
21
 		F Pröls, T Liehr, M Marx, B Rautenstrauss.
Regional localization of rat microvascular endothelial differentiation gene 1 (Mdg1) to chromosome 6q16-23 by means of FISH.
Mamm Genome 1996, 7:867-868.
1.890
 		CG
20
 		E Gebhart, P Hofbeck, Y Hofmann, R Lerch, G Schmitt, T Liehr.
Recovering of archival tumor cytogenetic slides for two-color-interphase FISH.
Appl Cytogenet 1996, 22:146-148.		 n.a. M
19
 		T Liehr, B Rautenstrauss, H Grehl, K D Bathke, A Ekici, A Rauch, H D Rott.
Mosaicism for the Charcot-Marie-Tooth disease type 1A duplication suggests somatic reversion.
Human Genet 1996, 98:22-28.		 3.145 CG
18
 		T Liehr.
PMP22-expression in Nervus suralis biopsies of CMT1A- and HNPP-patients studied by means of immunohistochemistry.
Futura 1996, 2:158-160.		 n.a. CG
M
17
 		T Liehr, H Grehl, B Rautenstrauss.
A rapid method for FISH analysis on interphase nuclei extracted from cryofixed tissue.
Trends in Genetics 1996, 12:505-506.		 16.342 M
coauthor or author in ~18% of publications of Institute of Human Genetics Erlangen in the actual year


 1995
Number
 		Authors/ Title/ Where Contribution was Published
 		Impact Factor Topic
16
 		T Liehr, K Thoma, K Kammler, C Gehring, A Ekici, K D Bathke, H Grehl, B Rautenstrauss.
Direct preparation of uncultured EDTA-treated or heparinized blood for interphase FISH analysis.
Appl Cytogenet 1995, 21:185-188. 		n.a. M
15
 		T Liehr, A Ekici, R Hillenbrand, B Rautenstrauss.
Regional localization of rat myelin protein zero Mpz gene to chromosome 13q24-25 by means of FISH.
Mamm Genome 1995, 6:824-825. 		1.890 CG
14
 		T Liehr, H Grehl, B Rautenstrauss.
FISH analysis of interphase nuclei extracted from paraffin-embedded tissue.
Trends in Genetics 1995, 11:377-378.		 16.342 M
13
 		D Bächner, T Liehr, H Hameister, H Altenberger, H Grehl, U Suter, B Rautenstrauss.
Widespread expression of the peripheral myelin protein-22 gene (pmp22) in neural and non-neural tissues during murine development.
J Neuroscience Res 1995, 42:733-741.		 3.126 CG
12
 		T Liehr, B Rautenstrauss.
Regional localization of rat peripheral myelin protein 22 (Pmp22) gene to chromosome 10q22 by FISH.
Mamm Genome 1995, 6:489.		 1.890 CG
11
 		E Gebhart, T Liehr, P Harrer, S Reichardt, G Schmitt, K Thoma, M Gramatzki, U Trautmann.
Determination by interphase FISH of the clonality of aberrant karyotypes in human hematopoietic neoplasias.
Leukemia and Lymphoma 1995, 17:295-302.		 1.140 TCG
10
 		T Liehr, H Altenberger, B Rautenstrauss.
Rapid fluorescence in situ detection of heterologous expression in E. coli and counterstaining with diaminophenylindol.
Trends in Genetics 1995, 11:129.		 16.342 M
coauthor or author in 35% of publications of Institute of Human Genetics Erlangen in the actual year

1994
Number
 Authors/ Title/ Where Contribution was Published
 Impact Factor Topic
9
 C Kraus, T Liehr, J Hülsken, J Behrens, W Birchmeier, KH Greschick, WG Ballhausen.
Localization of the human ß-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development.
Genomics 1994, 23:272-274.		 3.386
 TCG
8
 U Trautmann, M Gramatzki, M Krauß, A Fritz, T Liehr, E Gebhart.
Tetrasomy 8 as a clonal anomaly in myeloic neoplasias.
Cancer Genet Cytogent 1994, 72:101-104.		 1.756 TCG
7
 T Liehr, A Stübinger, K Thoma, H A Tulusan, E Gebhart.
Comparative interphase cytogenetics using FISH on human ovarian carcinomas.
Anticancer Research 1994, 14:183-218.		 1.375 TCG
6
 S Neubauer, T Liehr, H A Tulusan, E Gebhart.
Interphase cytogenetics by FISH on archival paraffin material and cultured cells of human ovarian tumors.
Int J Onc 1994, 4:317-321.		 1.381 TCG
coauthor or author in ~20% of publications of Institute of Human Genetics Erlangen in the actual year
 
1993
Number
 Authors/ Title/ Where Contribution was Published
 Impact Factor
Topic
5
 E Gebhart, U Trautmann, S Reichardt, T Liehr.
Chromosomal heterogenety of aneuploid leukemic cell populations detected by conventional karyotyping and by fluorescence in situ hybridization (FISH).
Anticancer Res 1993, 13:1857-1862.		 1.375 TCG
4
 E Gebhart, U Trautmann, S Reichardt, T Liehr.
Use of fluorescence in situ hybridization (FISH) for the estimation of the aberrant cell clone in leukemias with trisomy 8 or monosomy 7 detected by karyotyping.
Int J Onc 1993, 3:191-195.		 1.381 TCG
3
 T Liehr, N Atanasov, A H Tulusan, E Gebhart.
 Amplification of proto-oncogenes in human ovarian carcinomas.
Int J Onc 1993, 2:155-160.
 1.381 TCG
coauthor or author in ~15% of publications of Institute of Human Genetics Erlangen in the actual year
 
1992

Number
 Authors/ Title/ Where Contribution was Published
 Impact Factor
 Topic
2
 A Rauch, R A Pfeiffer, U Trautmann, T Liehr, H D Rott, R Ulmer.
A study of ten small supernumerary (marker) chromosomes identified by fluorescence in situ hybridization (FISH).
Clin Genet 1992, 4:84-90. 		1.391 sSMC
1
 T Liehr, RA Pfeiffer, U Trautmann.
Typical and partial cat eye syndrome: identification of the marker chromosome by FISH.
Clin Genet 1992, 42:91-96. 		1.391
 sSMC
coauthor or author in ~8% of publications of Institute of Human Genetics Erlangen in the actual year





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