ChromosOmics - Database

Icon by Leon Liehr              

                                                     - CHROMOSOME  19  -                                                   


Heterochromatic

- centromeric
- other heterochromatic variants
Euchromatic

- euchromatic deletions
- euchromatic duplications
References


Heterochromatic - (peri)centromeric variants

case no.
(molecular) cytogenetic result
clinical symptoms
reference
19-
p12p11+/
1-1 to many

der(19)(p12p11amp) = 19ph+
best visible in C-, Q-banding or inverted DAPI-banding (4% of cases)

none
{1, page 76}
19-
p12q12+/
1-1 to many

der(19)(p12q12amp) = 19qh+
best visible in C-, Q-banding or inverted DAPI-banding (9% of cases)

none
{1, page 76}
19-
q11q12+/
1-1 to many

der(19)(q11q12amp)
best visible in C-, Q-banding or inverted DAPI-banding (11% of cases)

none
{1, page 76}
19-
cen+/

1-1
19cen+
D19Z3 (stains 19p11.1 only!) = D1Z7 = D5Z2
here cases with D19Z3 enlargements have been seen which look in inverted DAPI like 19ph+ and 19qh+

none
{0; 1, page 76, Color Plate 4, VII}

Heterochromatic - other heterochromatic variants

case no.
(molecular) cytogenetic result
clinical symptoms
reference
19-
HHM-
own cep/
1-1 to many

D19Z3 (stains 19p11.1 only!)
gives always signals on 1p11.1q11 (=D1Z7) and 5p11 (D5Z2)

none
{1}
19-
HHM-
Xp11.1q11.1/
1-1

ins(19;X)(q10;p11.1q11.1)
none
{1, page 81; 59}

Euchromatic deletions

case no.
(molecular) cytogenetic result
clinical symptoms
reference
  19-
EHM-del
pterp13/

1-1
del(19)(p13)
none
{1}

Euchromatic duplications

case no.
(molecular) cytogenetic result
clinical symptoms
reference
19-
EHM-dup
p13.11q13.11/
1-1 to few

sSMC(19)
none
{sSMC
page}